Best Des Moines Grants for Nonprofits in Iowa

Agnes McCarthy Caregiver Foundation

The Agnes McCarthy Caregiver Foundation is a 501(c)(3) not-for-profit charity that provides hope and relief to caregivers who care for a loved one with mental health conditions.

Caregiver Grant

Family caregiving has become a public health issue that receives inadequate recognition in our country. While it can be rewarding to care for our loved ones, it often comes with significant physical, emotional and financial costs to the caregiver. On average, caregivers spend over 25% of their own income to support their loved one and provide 32 hours a week in unpaid care.

AMCF currently offers a $500 financial relief grant to assist family members with unexpected expenses due to their caregiving role. If you are a family caregiver to someone living with a mood or psychiatric condition like depression, anxiety, PTSD, bipolar, schizophrenia, or other mental health/co-occurring conditions, you are not alone, and we welcome you to apply for a caregiver grant today.

Additional Information

• To ensure our limited funds reach families with the greatest need, grants may require documentation confirming a diagnosed serious mental illness (SMI).  

• The $500 grant is limited to one award per household within a 12-month period.

• Applications are generally reviewed by our Board of Directors, with decisions made within 30 days of receipt.

T7 Social Impact GrantsThe T.D. Jakes Foundation (TDJF), in partnership with Wells Fargo, is proud to launch the Social Impact Grant Challenge, a transformative funding opportunity designed to identify, support, and amplify nonprofit organizations creating meaningful change in communities across the United States.

Designed around the T.D. Jakes Foundation's pillars of service (Educational Access & Workforce Readiness, financial inclusion, and community transformation and well-being), the Challenge seeks innovative nonprofit organizations that are addressing critical social issues through impactful, scalable, and sustainable solutions.

Finalists selected through this process will have the opportunity to showcase their organization through a live presentation at the inaugural Thriving Seven (T7) Summit, taking place November 12 –14 in Atlanta, Georgia. In addition to competing for grant funding, finalists will gain national visibility for their work and connect with nonprofit leaders, funders, and changemakers from across the country.Grant Funding: A total of $1,500,000 in grant funding is anticipated to be awarded: 

• One (1) - $500,000 grant
• One (1) - $250,000 grant
• Two (2) - $100,000 grant
• Eleven (11) - $50,000 grant

About Panorama GlobalPanorama Global is a social impact nonprofit that empowers changemakers through radical collaboration. We help our partners navigate the winding path from vision to impact. 

What We Do

• Collaboratives - Hosting and supporting collaborative efforts to achieve common goals.
• Fiscal Sponsorship - Financial and administrative support providing lean operating models to jumpstart projects.
• Funds - Philanthropic vehicles to manage and distribute funds that fuel global initiatives.

About  Innovative Postsecondary Models Fund

The Innovative Postsecondary Models (IPM) Fund supports innovative postsecondary education models that are rethinking how education is designed, delivered, financed, and assessed for learners in the United States.

The Fund is interested in innovations that benefit all learners, but especially learners whom the data show encounter the greatest obstacles to opportunity. The goal of this Fund is not only to provide funding to innovative models, but also to learn from selected grantees on how to reduce barriers to postsecondary access and increase student success outcomes to help inform the role philanthropy can play in supporting higher education innovation.

What We're Funding

We are seeking innovative postsecondary education models that demonstrate, or have the potential to demonstrate, meaningful improvements in how learners access, experience, and benefit from postsecondary education. We seek approaches with the potential to scale, influence the field, and inform how postsecondary education evolves nationally.

To help illustrate the types of innovations we hope to support, we have organized this opportunity around four broad themes. These themes reflect key dimensions of postsecondary innovation that have the potential to improve learner outcomes and inform broader systems change.

All four themes are grounded in a shared principle: student-centeredness. Truly innovative postsecondary models must be designed around learner needs, especially the needs of learners whom the data show face the greatest barriers to access and success in traditional postsecondary education.

Applicants are not expected to address all four themes, but should demonstrate strong alignment with at least one of the following:

Reimagining Instructional Design, Delivery, Assessment, and Student Support

• What success might look like:
  • Innovative instructional models improve student persistence, completion, and post-completion success, particularly for historically underserved learners, while maintaining or reducing costs.
  • Learners benefit from personalized, adaptive instruction and competency-based assessments that enable them to demonstrate and document skills in ways that are recognized by employers and other educational institutions.

Advancing Affordability and Financial Sustainability

• What success might look like:
  • Learners spend less overall, face reduced financial risk, and access high-quality education pathways that lead to credentials supporting economic mobility.
  • Successful models demonstrate affordability not only through reducing costs for learners, but also by maintaining or reducing the cost of delivering high-quality education through sustainable, efficient approaches.

Career and Workforce Alignment

• What success might look like:
  • Work and learning are more demonstrably connected and flexible, with evidence that skills are more directly tied to credentials and real career opportunities.

Removing Barriers for Underserved Learners

• What success might look like:
  • More learners from backgrounds and communities who the data show have faced the greatest barriers to accessing postsecondary education are able to access, complete, and benefit from high-quality credentials.

About  USA Track & Field Foundation IncThe USA Track & Field Foundation was established in 2002. Our Foundation provides a means to attract and guide funds to new and innovative track & field programs, with an emphasis on providing opportunities for youth and elite athletes.Mission: To support the development of emerging elite athletes, while fostering integration within the broader track & field community. To facilitate the physical, educational, social and character development of youth track & field athletes and to help prepare them to mature and succeed in adult life.About Youth Club GrantThe USATF Foundation considers providing opportunities for youth athletes to compete in track & field a top priority. We encourage youth track clubs and programs from all areas of the United States to apply for financial assistance.Examples of allowable expenses are as follows: equipment, uniforms, meet fees, travel, facility rental, staff and volunteer training and outreach.  

The USA Track & Field Foundation was established in 2002. Our Foundation provides a means to attract and guide funds to new and innovative track & field programs, with an emphasis on providing opportunities for youth and elite athletes.

Mission: 

To support the development of emerging elite athletes, while fostering integration within the broader track & field community. To facilitate the physical, educational, social and character development of youth track & field athletes and to help prepare them to mature and succeed in adult life.About USATF Maternity GrantTo be considered for a USATF Foundation Maternity Grant, please begin by filling out the Elite Grant Application. Our Maternity Grant Committee will utilize the application information to consider your grant request. In addition to the Elite Grant Application please send along a formal letter for the committee to review. USATF Foundation is accepting formal letters of request for funding throughout the year. The Maternity Grant committee will consider and award grants on a quarterly basis dependent on available funding.

Please include in your letter:

• A detailed description of your current situation (expecting or recovering from childbirth)
• Timeline including estimated due date and estimated time frame when your training became affected by pregnancy
• Include your intentions and plans for after child birth
• List your most recent competition date where you were in peak form and the time / mark of the performance
• Were you ever ranked in the top 20 in the US or top 50 in the world within the 2 years before you became pregnant? If yes, please list the ranking, month/year and by what source.
• How Foundation funding would benefit you personally and in your track & field/running career.

The OVC FY 2026 Enhanced Collaborative Model (ECM) Task Force to Combat Human Trafficking aims to strengthen responses to human trafficking through multidisciplinary collaboration. This initiative provides essential resources for victim identification, service delivery, and case investigations, all supported by the U.S. Department of Justice. By fostering cooperative efforts, the program seeks to enhance the effectiveness of local jurisdictions in combating this critical issue and ensuring the safety and rights of affected individuals.

Mission: A non-profit, charitable, Private Foundation established in 1959 by the Long family to support local charities, schools, education events and general community needs.

Grants

Our approach to grant requests focuses on fostering local neighborhood vitality and excellence. The John F. Long Foundation supports local non-profit organizations that promote this objective. The Foundation looks for groups who are working to help themselves, help their own communities, and help others like themselves through self-empowering, community organizing efforts. To be eligible for consideration, the grant request must meet the following criteria:

• Funds’ use must have measurable benefits
• Your organization must have good management, a solid financial background, well-established administration policies and Board of Directors
• The grant request must be precise and complete, providing necessary detail
• The Foundation Questionnaire is to be completed in its entirety
• The grant request amount and time frame must be clearly communicated, i.e. one-time grant, ongoing support, or special project
• If your request is for a particular event or program, providing a budget is always helpful
• Requests for grants of $1,000.00 or more, as well as groups we have not funded within the past two years, must: (i) Provide financial reports/statements for past and current fiscal year; (ii) Provide a list of past donors going back no more than two years.

2026 ASPCA Grants for Shelters and Spay/Neuter Clinics

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) is offering up to $14 million in grants to support shelters and spay/neuter clinics in meeting the needs of vulnerable animals throughout the United States, including addressing the shortfall in available spay/neuter surgeries. We will fund qualified proposals that support:

• Critical shelter infrastructure
• Strengthening shelter essentials
• Increasing the number of spay/neuter surgeries year-over-year 
• Major capital projects that increase spay/neuter capacity
• Special projects that increase spay/neuter capacity

Shelter Grants

Critical Shelter Infrastructure

Only one application per agency/organization will be considered. 

Applicants may choose only one of the five funding categories. Our interest is in meeting your most pressing needs in one of the offered categories; we do not have our own preference for funding one category over another. We will fund the most compelling proposals, regardless of category chosen.

2026 ASPCA Grants for Shelters and Spay/Neuter Clinics

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) is offering up to $14 million in grants to support shelters and spay/neuter clinics in meeting the needs of vulnerable animals throughout the United States, including addressing the shortfall in available spay/neuter surgeries. We will fund qualified proposals that support:

• Critical shelter infrastructure
• Strengthening shelter essentials
• Increasing the number of spay/neuter surgeries year-over-year 
• Major capital projects that increase spay/neuter capacity
• Special projects that increase spay/neuter capacity

Shelter Grants

Strengthening Shelter Essentials

Only one application per agency/organization will be considered. 

Applicants may choose only one of the five funding categories. Our interest is in meeting your most pressing needs in one of the offered categories; we do not have our own preference for funding one category over another. We will fund the most compelling proposals, regardless of category chosen.

2026 ASPCA Grants for Shelters and Spay/Neuter Clinics

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) is offering up to $14 million in grants to support shelters and spay/neuter clinics in meeting the needs of vulnerable animals throughout the United States, including addressing the shortfall in available spay/neuter surgeries. We will fund qualified proposals that support:

• Critical shelter infrastructure
• Strengthening shelter essentials
• Increasing the number of spay/neuter surgeries year-over-year 
• Major capital projects that increase spay/neuter capacity
• Special projects that increase spay/neuter capacity

Spay/Neuter Grants

Increasing Spay/Neuter Surgeries

Only one application per agency/organization will be considered. 

Applicants may choose only one of the five funding categories. Our interest is in meeting your most pressing needs in one of the offered categories; we do not have our own preference for funding one category over another. We will fund the most compelling proposals, regardless of category chosen.

2026 ASPCA Grants for Shelters and Spay/Neuter Clinics

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) is offering up to $14 million in grants to support shelters and spay/neuter clinics in meeting the needs of vulnerable animals throughout the United States, including addressing the shortfall in available spay/neuter surgeries. We will fund qualified proposals that support:

• Critical shelter infrastructure
• Strengthening shelter essentials
• Increasing the number of spay/neuter surgeries year-over-year 
• Major capital projects that increase spay/neuter capacity
• Special projects that increase spay/neuter capacity

Spay/Neuter Grants

Spay/Neuter Major Capital Projects

Only one application per agency/organization will be considered. 

Applicants may choose only one of the five funding categories. Our interest is in meeting your most pressing needs in one of the offered categories; we do not have our own preference for funding one category over another. We will fund the most compelling proposals, regardless of category chosen.

The ASPCA is offering up to $14 million in Spay/Neuter Grants for shelters and clinics across the U.S. to enhance spay/neuter services for vulnerable animals. Proposals can address critical infrastructure needs and major capital projects to increase spay/neuter capacity. Only one application per organization is permitted, and applicants must choose one funding category. The focus is on compelling proposals that meet the most urgent needs.

The Amy Adina Schulman Memorial Fund

The Amy Adina Schulman Memorial Fund is a Princeton, New Jersey-based endowment fund providing grants to individuals, young adults who volunteer or intern for progressive social action projects or programs in an area of their interest and commitment. The Amy Adina Fund also sponsors a lecture each year on a relevant and timely topic related to its educational mission.

The Amy Adina Schulman Memorial Fund was started in 1987 one year after Amy Adina, 20, died suddenly while a student and activist at Rutgers University. It is a realization of her family and her communities’ desire to celebrate her life, to fulfill her dreams and her potential. Since its inception, almost 1,500 grants have been awarded for work in Africa, Asia, Latin America, the Middle East, and the United States—nearly $1,000,000 in total. The Amy Adina Schulman Memorial Fund is a 501(c)3 nonprofit organization.

About Our Grants

Small grants (depending on length of service), are awarded to as many applicants as possible rather than giving larger amounts to fewer individuals. The number of awards has grown each year thanks to annual contributions as well as to gifts sent to the Fund to honor special occasions and life cycle events.

The Fiscal Year 2027 AmeriCorps Seniors RSVP Competition invites communities to apply for funding aimed at engaging adults aged 55 and older in addressing pressing local needs. Through national service and volunteerism, AmeriCorps strengthens communities and fosters civic engagement. This open competition spans all states and territories, encouraging organizations to harness the skills and expertise of older adults to enhance community well-being and promote a culture of service.

The OVC FY 2026 grant aims to improve outcomes for child and youth victims of human trafficking by integrating policies at state and Tribal levels. This funding opportunity focuses on developing strategic plans to address the challenges faced by minor victims, enhance coordination among systems like child welfare and juvenile justice, and ensure effective identification and prosecution of traffickers. By fostering multidisciplinary approaches, the program seeks to provide comprehensive support and services to these vulnerable populations.

The FY26 Breast Cancer Research Program's Clinical Research Extension Award aims to enhance breast cancer clinical studies by extending data collection and follow-up. This funding mechanism emphasizes the importance of patient participation and addresses challenges from early trial terminations. Notably, applications must include two breast cancer consumer advocates and can feature either a single Principal Investigator or a duo. This initiative seeks to improve outcomes through comprehensive data analysis and patient engagement.

The National Fish Passage Program (NFPP) offers vital assistance for removing barriers to aquatic life, enhancing safety, and promoting local economies. By investing in projects like culvert replacements and floodplain restorations, the program not only supports native fish populations but also delivers significant economic benefits, estimated at $1.5 million for every $1 million invested. With a recent allocation of $15 million, including $5 million for specific restoration initiatives, NFPP continues to advance aquatic connectivity nationwide.

The Small Instruments and Modern Equipment program invites shared-use biomedical research facilities to apply for funding to purchase small instruments or scientific equipment. These resources, which may include core facilities and biorepositories, aim to enhance operational efficiency and support the use of innovative technologies. Funding is specifically targeted for instruments that produce outputs beyond traditional digital data, excluding highly specialized or building-level infrastructure equipment.

The Children and Youth with Special Health Care Needs Research Network aims to enhance the lives of children and youth with special health care needs (CYSHCN) and their families. By establishing a robust research infrastructure, the program will generate evidence-based solutions to foster well-being and community engagement. It focuses on identifying effective interventions and measures that can be integrated into essential services and supports, ultimately helping CYSHCN thrive throughout their lives.

The Regional Excellence for Access to Comprehensive Care for Hemophilia Networks (REACH Networks) aims to enhance access to coordinated, evidence-based care for individuals with hemophilia and related disorders. This initiative will broaden access to comprehensive care, implement quality improvement projects, and provide ongoing training and education for Hemophilia Treatment Center staff. The focus is on improving best practices for comprehensive, collaborative care, including effective lifespan transitions for patients.

About Americans for the Arts

Building Collective Power for the Arts

Americans for the Arts is the nation's leading arts advocacy organization. We mobilize advocates, produce trusted research, and secure bipartisan wins that protect funding and expand arts access nationwide — work we've been doing for more than 65 years.

Americans for the Arts advances the people, organizations, and systems supporting arts and culture across America through advocacy, research, and national convening.

We envision a nation where freedom of creative expression is upheld as a fundamental human right, where arts and culture are woven into the fabric of civic life, resourced in every community, and accessible to everyone.

Request for Proposals (RFP)

Strengthening Leadership Capacity of Local Arts Agencies

Given the essential role of LAAs, and to meet this important moment, AFTA seeks an energized and experienced consulting team with expertise to help it develop a comprehensive strategy to strengthen leadership and field capacity across the LAA ecosystem. This work is not intended to operate in isolation, but rather to complement and build upon existing efforts already underway in the field. The focus is on identifying where AFTA can add value through targeted, strategic support that enhances and aligns with broader sector-wide initiatives. 

This effort will focus on empowering LAA agency leaders—a critical component of AFTA’s strategic direction—to expand their capacity, foster innovation, and advance equity in a rapidly evolving environment. Building on existing efforts across the field, AFTA will invest in strong, effective LAA leadership, broaden cultural access and participation nationwide, and position the field for a more vibrant, resilient, and sustainable future. 

With approximately 2,200 LAAs nationally validated in AFTA’s LAA Wayfinder, the selected consulting team will help AFTA gain a deeper understanding of the gaps, needs and opportunities shaping LAA leadership capacity, with attention to Native, rural, small, midsize, and large communities, and identify where AFTA is uniquely positioned to contribute. These insights will guide AFTA’s future direction in its service to LAAs nationwide and ensure AFTA’s contributions complement—rather than duplicate—the work of other entities, collectively strengthening the broader LAA ecosystem.  

In addition, by intentionally working in partnership with peer organizations and stakeholders across the field—and by understanding gaps in coverage and opportunities for growth—AFTA will be positioned to work with partners to support the expansion of the LAA network in communities where local public cultural infrastructure is limited or absent. This collaborative approach will help ensure more equitable access to arts and culture while reinforcing the role of LAAs as essential community anchors, particularly in underserved regions. 

About the Foundation

There is no health without mental health. The APA Foundation is working in your community to provide the support and resources we all need to prioritize mental wellbeing where you live, learn, work, worship, and play.

Our Mission

Promote the mental health and well-being of individuals and communities.

Our Vision

A mentally healthy nation for all – where we live, learn, work, worship, and play.

Psychiatric Research Fellowship

The Psychiatric Research Fellowship provides funding for an early research career psychiatrist to design and conduct a health services/policy-related research study using national data housed at the APA. The Fellow's research activities will be carried out under the supervision and guidance of a mentor at his/her institution in collaboration with his/her mentor(s) at the APA Division of Research. This vital program will enable the APA and APA Foundation to actively participate in sustaining and strengthening the clinical investigators workforce specifically in psychiatry.

Program Benefits

• Receive funding (up to $45,000 per year) towards a research study that will address a major research topic impacting psychiatric practice.
• Receive mentorship from established researchers in the field of psychiatry in the design and implementation of his/her research study.
• Access to secondary national data (e.g., CMS Claims data; APA Registry data) to carry out his/her research study.
• Present his/her research at one or more APA meetings.
• Opportunity to attend additional meetings that provide further mentorship in psychiatric research (e.g., Early Research Career Breakfast).
• Have access to a lifetime network of APA member experts working in the field of psychiatric research.
• Establish relationships and peer-mentorship with a diverse group of residents and fellows with similar career interests and goals.
• Participate on an assigned APA Council or APAF initiative where organizational decisions are made.
• Gain an understanding of APA Governance through service on an APA Council, Committee or APAF initiative.
• Appear in the APA Convocation of Distinguished Fellows Program Book listings.

The National Institute on Minority Health and Health Disparities (NIMHD) is offering funding for innovative research aimed at improving health outcomes for Native Hawaiian and Pacific Islander populations. This grant will support preparatory and pilot activities that focus on understanding health disparities, testing interventions for chronic diseases, and promoting health behavior changes in collaboration with community partners. Projects should address critical health issues such as cancer, diabetes, and maternal health.

Pediatric Dermatology Research Alliance Inc 

PHACE syndrome is a neurocutaneous syndrome characterized by large segmental infantile hemangiomas of the face and scalp in association with congenital anomalies that may affect the posterior fossa of the brain, cerebral and cervical arteries, heart, and/or eyes. LUMBAR syndrome is the lower-body counterpart of PHACE, characterized by large segmental infantile hemangiomas of the lumbosacral, buttock or pelvic regions associated with urogenital, spinal, bony, anorectal, and/or renal abnormalities. Those affected experience a wide range of comorbidities with significant psychosocial impact. We invite proposals for clinical research that improves diagnostic approaches, enhances quality of life, and addresses key aspects of disease burden and management.

Applications may be submitted by either a single investigator or multiple investigators at multiple institutions. A total of $40,000 is available and may be awarded as one large-scale project or as multiple smaller awards, depending on the number and quality of applications received. Equal consideration will be given to projects in either of the two award formats with decisions to be based upon merit and available funds.

Focus

Research should focus on PHACE and/or LUMBAR syndromes. Priority will be given to investigators who have not previously served as the senior investigator on an R01 NIH grant or equivalent, and to studies that include multidisciplinary teams with active roles for early-career investigators. Proposals that meaningfully integrate patient perspectives are strongly encouraged.

Important Details

• Up to $40,000 will be funded to support one large-scale project for up to two years, or as multiple awards for smaller-scale projects

The Capacity Building Grants for Non-Land-Grant Colleges of Agriculture Program, administered by the USDA's NIFA, aims to enhance the capabilities of eligible institutions in agriculture and related fields. By providing financial support, the program encourages institutions to compete for federal funding, disseminate vital information, and foster community engagement in educational and research initiatives. This initiative is crucial for developing infrastructure, promoting faculty development, and establishing graduate assistantships to address national and regional agricultural priorities.

About Colin Farrell FoundationThe Colin Farrell Foundation is committed to transforming the lives of individuals and families living with intellectual disability through education, awareness, advocacy, and innovative programs. Inspired by his two sons, he is excited and deeply humbled by the hope that the Colin Farrell Foundation can help those who the larger systems of governance have neglected.

CFF Innovation GrantsWe’re looking for bold, scalable solutions focused on one or more of these priority areas:

• Affordable co-housing models for individuals and families
• Employer-partnered day programs and inclusive job opportunities
• Tools and technologies that enhance accessibility at home and in community spaces
• Cross-sector collaborations between public, private, and nonprofit organizations

The SEFSC Bluefin Tuna Research Program aims to enhance science-based fisheries management for Atlantic bluefin tuna by improving knowledge of their fisheries, biology, and population dynamics. This initiative encourages collaborations with ICCAT and its partners to support multi-year research efforts focused on the movement and mixing of eastern and western Atlantic bluefin populations, ultimately contributing to better management practices for sustainable fisheries.