Best Large Grants for Nonprofit Organizations in District of Columbia

The DoW Rare Cancers Idea Development Award promotes innovative research ideas for rare cancers, encouraging applicants to provide preliminary data and exploratory aims. This funding opportunity, offered by the US DOD: U.S. Army Medical Command, seeks projects with the potential for high-impact findings that can significantly benefit the patient community. It aims to foster new avenues of investigation and support discovery-driven research in the field of rare cancers.

The 2026 Rare Cancers Research Program Resource and Community Development Award aims to enhance rare cancer research through improved resources and datasets. It addresses critical gaps in research resources, communication strategies, and data sharing infrastructures. Key features include engaging patient advocates throughout the research process and ensuring sustainability of community platforms. This funding opportunity emphasizes community building and the dissemination of findings to benefit scientific and patient communities alike.

The FY26 Joint Warfighter Medical Research Program's Military Medical Research and Development Award aims to fund the continuation of previous Department of War-funded research addressing high-priority medical needs for Service Members and Military Health System beneficiaries. It supports various projects, including late-stage preclinical studies and clinical research. Eligibility requires prior DOD funding, and a Clinical Research Option is available for studies involving human subjects or biological samples.

The James B. Linsmayer Foundation Grant supports programs in arts, culture, education, health, and human services primarily within the Twin Cities of Minnesota. Established in memory of James B. Linsmayer, the foundation aims to be a strategic partner in these vital areas. Eligible grantees include public charities recognized under IRC guidelines, with no geographic limitations but a preference for local organizations. While start-ups may be considered, funding for organizational expenses is not permitted.

The USPOULTRY Research Grants program, sponsored by the U.S. Poultry and Egg Association, aims to enhance the poultry industry through comprehensive research funding. Established in 1963, it supports diverse projects related to poultry and egg production. With over $30 million invested, the program emphasizes improving product quality and safety. Proposals are evaluated by a panel of experts, with a funding rate of 15-20%. Eligible projects typically have budgets under $80,000 and timelines of 1-2 years.

The BMC Expedition Grant supports British climbers for international expeditions, prioritizing those who have been BMC members for at least two years. Grants are aimed at younger climbers and under-represented groups, promoting sustainable practices in expedition planning. Eligible teams must demonstrate a commitment to climbing and innovative objectives, while ineligible projects include commercial expeditions and those failing to adhere to grant conditions. This funding aims to foster significant personal development and environmentally conscious climbing.

The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.

The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders 

There remains a scientific gap in understanding of the role of anti-TFP Imediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Geographic Scope

Brazil, China, Europe, Israel, Japan, Saudi Arabia, South Korea, Turkey, USA

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

The Alpha Omega Alpha/Pharos Poetry Award

To encourage students to write effective poetry. Winning poems are published in The Pharos.

The Award

Up to 5 poems will receive a $1,500 award. The winning entries will be published in The Pharos.

Summer Medical Internship Program (SMIP)

Fosters an interest in research by funding a summer research project conducted by a medical student.

The SIR Foundation Summer Medical Internship Program introduces medical students to interventional radiology research and medical device development. The goal of this program is to foster an interest in research by funding a summer research project conducted by a medical student.

Students applying for the program must show strong potential for a career in IR with proven academic success. Selected students will have an opportunity to intern with an interventional radiologist research mentor or corporate research and development mentor for 8 weeks during the summer.

SIR Foundation will provide a $6,000 stipend to help ease the financial burdens throughout their internship experience.

• Budget: Up to $6,000
• Grant Length: Eight weeks

Investigating the Benefit of Early Treatment with Ritlecitinib in Alopecia Areata: A Real-World Evidence Approach

Alopecia Areata (AA) is a chronic, immune-mediated condition causing nonscarring hair loss that affects about 2% of the global population and can lead to substantial psychosocial burden if disease is severe and untreated. The treatment landscape has recently evolved with the approval of ritlecitinib, a systemic therapy for severe AA in adults and adolescents aged 12 years and older, based on efficacy demonstrated in the ALLEGRO phase 2b/3 program.

Despite this advance, important questions remain regarding the optimal timing of therapy initiation. Emerging post-hoc analyses from the ALLEGRO program indicate that patients with shorter disease duration and lower baseline severity achieve higher response rates, suggesting that earlier intervention with ritlecitinib may lead to improved outcomes.

Geographic Scope

United States 

Funding Range and Project Length

Individual projects requesting up to $100,000 USD will be considered.

Maximum project length is 24 months.

Hemophilia Fellowship

This competitive grant program seeks to support an institution-based fellowship that emphasizes shared decision making (SDM), patient education, and multidisciplinary team-based care. The intent is to strengthen the hemophilia care through equitable education, and patient-centered shared decision making in a rapidly evolving treatment landscape.

Geographic Scope

• United States 

Funding Range and Project Length

• Grant funding is available to support a one year fellowship up to $100.000 USD. 

The SPARK-EHS initiative aims to broaden the reach of NIEHS training by launching innovative environmental health programs for predoctoral trainees at institutions without recent NIEHS T32 funding. This initiative focuses on research regarding the impact of the environment on biological systems and seeks to translate findings into practical health solutions. Eligible institutions will receive support for developing and implementing these targeted training programs, fostering advancements in environmental health research.

Clinical Research Training Scholarship in Autoimmune Neurology

This award recognizes the vital importance of rigorous clinical and translational research and aims to inspire and support early-career investigators pursuing clinical studies in autoimmune neurology — specifically immune-mediated diseases of the nervous system other than multiple sclerosis.

The scope of this award encompasses research on autoimmune neurologic disorders, including neural antibody-associated diseases of the nervous system, autoimmune encephalitis, immune-mediated epilepsy, autoimmune movement disorders, inflammatory myelopathies, NMOSD, MOGAD, paraneoplastic neurological syndromes, neurological complications of cancer immunotherapies, and inborn errors of immunity/autoinflammatory syndromes affecting the nervous system.

This award will consist of a commitment of $65,000 per year for two years, plus a $10,000 per year stipend to support education and research-related costs for a total of $150,000. Supplementation of the award with other grants is permissible, but to be eligible to apply for this award, the other grant source(s) cannot exceed $75,000 annually.

The Oak Foundation's Learning Differences Grant Programme aims to foster equitable educational experiences for students with learning differences, particularly those marginalized by racism and poverty. Through strategic partnerships with not-for-profit organizations, the program enhances understanding of diverse learners' needs, translates knowledge into effective practices, and influences systemic changes to create supportive learning environments. The initiative emphasizes the importance of community involvement, ensuring that students' voices are heard and their educational needs are met.

Bob Brittain Memorial Scholarship/CCHS Alumni Scholarship

Presented by the Columbia City High School Alumni Association

Criteria are the same for a two year degree and four year degree. This scholarship is one-time and non-renewable.

The ideal recipient of this scholarship will be a CCHS graduate who has been actively involved in several extra-curricular activities, major service activities, and have a grade point average reflective of respectable academic growth. This student will have a four year involvement in the activities listed below. This student will also be fully involved in high school classes during the final trimester of the senior year

Community Foundation of Noble County

At the Community Foundation of Noble County we are passionate about making Noble County an even better place to call home. Since 1991, area residents have been turning to the Community Foundation of Noble County to make their philanthropic giving as effective as possible, as we see it as our mission to serve as a catalyst for positive change. The Community Foundation of Noble County is a public charity 501 (c) 3 entity.

Scholarships

The Community Foundation of Noble County offers a wide range of scholarships to support local students in achieving their academic and career aspirations. 

Kile, David O. & Marjorie B. Kile Scholarship

This scholarship is available to any Noble County resident who is at least 19 years of age with a high school diploma, or GED, in pursuit of higher education in a field of their choice. This scholarship is available to applicants planning to attend, or are currently enrolled, either full-time or part-time, in an accredited vocational school, or two-year or four-year college or university. The award is given one time, with no restriction on applying in subsequent years, for educational purposes only.

Community Foundation of Noble County

At the Community Foundation of Noble County we are passionate about making Noble County an even better place to call home. Since 1991, area residents have been turning to the Community Foundation of Noble County to make their philanthropic giving as effective as possible, as we see it as our mission to serve as a catalyst for positive change. The Community Foundation of Noble County is a public charity 501 (c) 3 entity.

Scholarships

The Community Foundation of Noble County offers a wide range of scholarships to support local students in achieving their academic and career aspirations. 

Schermerhorn, John and Mary Memorial Scholarship Fund

For a high school senior who is a Noble County resident who will graduate from Central Noble High School or East Noble High School or West Noble High School and is pursuing a career in an agriculture-related field. One-time payment of $500. 

Community Foundation of Noble County

At the Community Foundation of Noble County we are passionate about making Noble County an even better place to call home. Since 1991, area residents have been turning to the Community Foundation of Noble County to make their philanthropic giving as effective as possible, as we see it as our mission to serve as a catalyst for positive change. The Community Foundation of Noble County is a public charity 501 (c) 3 entity.

Scholarships

The Community Foundation of Noble County offers a wide range of scholarships to support local students in achieving their academic and career aspirations. 

Slater, Jonah W. Memorial Scholarship Fund

For a resident of Noble County who is pursuing any sort of post-secondary education. Pays $500 one time for the fall.

Community Foundation of Noble County

At the Community Foundation of Noble County we are passionate about making Noble County an even better place to call home. Since 1991, area residents have been turning to the Community Foundation of Noble County to make their philanthropic giving as effective as possible, as we see it as our mission to serve as a catalyst for positive change. The Community Foundation of Noble County is a public charity 501 (c) 3 entity.

Scholarships

The Community Foundation of Noble County offers a wide range of scholarships to support local students in achieving their academic and career aspirations. 

Sneary, M.D. Max Memorial Scholarship Fund

Awards $2,500 one-time for a high school senior from Noble County to pursue a career in the medical field, with preference given to East Noble applicants.

Rochester Area Community Foundation

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission: We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Victor and Janet Salitan BOCES 2 Scholarship

Purpose of Scholarship

To provide scholarship assistance for BOCES 2 Career and Technical Education students planning to pursue post-secondary education.

Allowed Use of Award

Awards may be used for tuition, fees, books, and other expenses associated with higher education.

Renewability

This scholarship is a one-time award and is not renewable.

Donor Information

This scholarship was established in 1979 to honor Victor Salitan. Victor served for 30 years as a school district attorney for several school districts and specifically for the Monroe 2-Orleans BOCES.

United Negro College Fund

“A mind is a terrible thing to waste.”®

For more than seven decades, this principle has remained at the heart of UNCF, enabling us to raise more than $5 billion and help more than 500,000 students and counting not just attend college, but thrive, graduate and become leaders.

We do this in three ways: By awarding more than 12,000 students scholarships, worth more than $65 million, each year. By providing financial support to 37 historically Black colleges and universities (HBCUs). And by serving as the nation’s leading advocate for the importance of minority education and community engagement.

MetLife Foundation Legacy Endowed Scholarship

The MetLife Foundation Legacy Endowed Scholarship Program was established by the MetLife Foundation to provide need-based scholarship support to college junior enrolled at US four-year HBCUs. Successful applicants must be currently pursuing a STEM, business, finance, or accounting degree, as a full-time student at a four-year HBCU.

Community Foundation of Monroe County

The Community Foundation of Monroe County (CFMC) builds a thriving, inclusive community through the power of philanthropy. By connecting generous donors with local causes, we help ensure Monroe County remains a place where everyone can thrive. Since our founding, we’ve been a trusted steward of community resources, fostering impactful collaborations and sustainable solutions to address challenges in education, health, poverty, and community development.

Scholarship Opportunities

We award over 120 scholarships each year to Monroe County residents. Whether you’re heading to college, pursuing a technical career, or furthering your education as an adult, there’s a scholarship for you.

Charles and Virginia Whitten Scholarship

For Monroe County high school seniors pursuing skilled trades.

Community Foundation of Monroe County

The Community Foundation of Monroe County (CFMC) builds a thriving, inclusive community through the power of philanthropy. By connecting generous donors with local causes, we help ensure Monroe County remains a place where everyone can thrive. Since our founding, we’ve been a trusted steward of community resources, fostering impactful collaborations and sustainable solutions to address challenges in education, health, poverty, and community development.

Scholarship Opportunities

We award over 120 scholarships each year to Monroe County residents. Whether you’re heading to college, pursuing a technical career, or furthering your education as an adult, there’s a scholarship for you.

Graceful Memories Memorial Endowed Scholarship

For Monroe County residents pursuing a career in medicine.

The Frances M. Culbertson Travel Grant provides essential funding for women from developing countries at the beginning of their psychology careers. This grant helps address the challenges posed by limited resources, allowing recipients to attend international and regional conferences. Eligible applicants must hold a doctoral degree and be within ten years postdoctoral, promoting diversity in the field. Preference is given to those attending key psychology conferences, fostering professional growth and networking opportunities.