Best Large Grants for Nonprofit Organizations in District of Columbia

The MIND Prize, funded by The Pershing Square Foundation, supports innovative research to combat neurodegenerative diseases like Alzheimer's. It empowers early-to-mid-career investigators to explore unconventional approaches and fosters collaboration across disciplines. Each winner receives $250,000 annually for three years, promoting advancements in neuroscience and creating a unique network for researchers. The initiative aims to enhance our understanding of brain health and tackle pressing societal challenges.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For technically ambitious or higher-risk, earlier-stage concepts focused on feasibility testing, assay or workflow prototyping, and initial cost-reduction validation. Intended approaches that require focused development to demonstrate viability.

The Ronald Barnes Memorial Grant, offered by The Guild of Carillonneurs in North America, supports North Americans pursuing studies in carillon performance, composition, music history, or instrument design. Established in 1998 to honor Ronald Barnes, a significant figure in carillon music, the grant has awarded over US$140,000 since 2007. For the 2025 cycle, grants of up to US$14,138 are available, depending on the number of successful applicants, promoting education in this unique art form.

The Jacquelin Goldman Congressional Fellowship offers developmental and clinical psychologists a unique opportunity to gain public policy experience while enhancing the application of psychological knowledge in government. Funded by the American Psychological Foundation, this fellowship supports one fellow annually with a stipend of $75,000 to $90,000, along with health insurance reimbursement and professional development funds. Applicants must demonstrate expertise in child psychology and policy issues, and have strong communication skills.

The Pediatric Visiting Professorship, funded by the Rheumatology Research Foundation, aims to recognize exceptional scientific abstracts from pediatric rheumatology fellows at ACR Convergence. This award facilitates knowledge sharing and promotes advancements in rheumatic disease care. The professorship spans two to three days and includes diverse teaching formats. Selected fellows receive a $1,000 honorarium for virtual visits or $1,500 for in-person engagements, along with reimbursement for travel expenses, enhancing the future of pediatric rheumatology education.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For concepts with preliminary feasibility evidence that are ready to advance from prototype toward an integrated workflow—optimizing performance, broadening assay or pathogen coverage, and generating more robust cost-reduction and performance data.

The Bob Skiera Memorial Fund Building Bridges Initiative Grant Program supports urban forestry research and collaboration. With a maximum award of $30,000, it aims to enhance communication between arborists, urban foresters, and various professionals. The program welcomes proposals that explore the benefits of urban forests, policy implementation, and ecosystem services. This initiative honors Bob Skiera's legacy, fostering trust and cooperation within the urban planning community for sustainable urban forestry practices.

The USA Dry Pea and Lentil Council (USADPLC) invites research proposals for pulse crops, focusing on breeding, nutrition, crop management, and product development for the 2023-24 fiscal year. Projects should adopt a transdisciplinary approach to tackle complex challenges, with average awards around $30,000. Researchers are encouraged to leverage industry funding for matching grants. Note that equipment purchases over $10,000 are not eligible. Compliance with specific proposal guidelines is essential.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For more mature concepts aimed at workflow refinement, performance optimization, and generation of proof-of-concept and validation data in relevant public-health use cases in LMICs.

The Melanoma Career Development Award (CDA) is offered by the Melanoma Research Foundation to support researchers dedicated to melanoma and its prevention. This award is designed for postdoctoral fellows with under five years of experience, research associates, scientists, staff scientists, assistant professors, and those focusing on melanoma prevention. The initiative promotes innovative research to advance understanding and treatment of melanoma, ultimately aiming to reduce its impact.

The NANFA Conservation Research Grant, offered by the North American Native Fishes Association, supports research focused on conserving North America's indigenous fish species, particularly those that are threatened or endangered. With a maximum funding of $1,000 per proposal, this grant is open to academia, conservation groups, and independent researchers. Since 2001, NANFA has aimed to enhance knowledge about native fishes and promote their conservation through scientific research and community engagement.

About Us

Driving Positive Change in Noble County!

At the Community Foundation of Noble County we are passionate about making Noble County an even better place to call home. Since 1991, area residents have been turning to the Community Foundation of Noble County to make their philanthropic giving as effective as possible, as we see it as our mission to serve as a catalyst for positive change. The Community Foundation of Noble County is a public charity 501 (c) 3 entity.

As a group of invested community members, we identify local current and emerging issues and stimulate resources to address those needs, helping our region prepare for the future. We then leverage gifts and bequests from generous donors like you to drive positive change through grants in such areas as arts and culture, education, health and human services, civic affairs and other charitable areas of interest.

Our Mission

To improve the quality of life in Noble County by serving as catalyst for positive change, enabling donors to carry out charitable intent, and making grants.

Donor Story – Joest, Brian H. Memorial Fund

Brian Henry Joest was born in Lagrange, Indiana in 1957. He grew up on the Atwood family farm that was settled by his ancestors in the mid-1800s. Now a historical Hoosier Homestead, the Atwood Farm provided him with all the outdoor activities possible for a farm boy in northern Indiana. Brian’s love of nature and the outdoors continued throughout his life. After high school, he attended Glen Oaks Community College and then Purdue University, where he earned a Bachelor of Science degree in Agricultural Economics

For decades, Brian went on annual backcountry camping and canoeing trips across the US and Canada. He paddled some of the most beautiful rivers in North America. He took a road trip to remote northern Alaska. He camped out on an active volcano in Guatemala. He explored most of the US National Parks. In his later years, his travels were less rustic but still adventurous as he and his wife, Cindy, checked off many items on his bucket list. They traveled to Paris, Rome, Florence, the Amalfi Coast of Italy, Ireland, and all around the US and Canada.

Brian began his professional career with management positions at Many Glacier Hotel at Glacier National Park in Montana; the Grand Hotel on Mackinac Island, Michigan; the Mountain View Grand Resort in New Hampshire; and Copper Mountain Ski Resort in Colorado. He also worked for Marriott Corporation where he opened new hotels across the Midwest.

Upon the birth of his first child, Brian moved his young family back to Lagrange County so his children could grow up on the Atwood Farm near their family. Brian worked for Life Care Center of Lagrange, was a substitute teacher for the Lakeland School District, and worked for fifteen years for East Noble School Corporation, most recently as an Instructional Assistant for high school students with special needs.

Brian enjoyed doing things for other people and took so much joy in their happiness. His career choices reflected his servant’s heart. He loved working in the hospitality industry and being able to make someone else’s vacation more memorable. He helped the patients and their families at Life Care Center. He spent years making a difference for students in our local schools.

Brian experienced first-hand the unique challenges faced by the families of individuals with special needs. He was a father, stepfather, and step-grandfather to children with different disabilities. He understood the difficulties of navigating support systems and knew there are gaps in these systems that result in unmet needs. At the end of his life, while he was fighting cancer, Brian dreamed of being able to return to the classroom to help special needs students. This was not to be. In 2022, his family created this fund in his honor with the intent of continuing his dream to help improve the lives of individuals with special needs.

The Melanoma Established Investigator Award offers up to $125,000 annually for two years, aimed at established melanoma researchers or senior researchers transitioning into melanoma research. Eligible applicants include Associate Professors or higher, with both tenured and non-tenured faculty encouraged to apply. U.S. citizenship is not a requirement for this funding opportunity provided by the Melanoma Research Foundation.

The MRFBC Young Investigator Team Award supports innovative research in immuno-oncology for melanoma, offering up to $150,000 annually for two years. This funding targets U.S.-based researchers aiming to enhance clinical outcomes for melanoma patients or deepen the scientific understanding of immuno-oncology. The MRF collaborates with key institutions to address challenges in melanoma research, fostering partnerships that maximize research potential and impact.

The NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44) invites small businesses to submit applications for investigator-initiated clinical trials. This program particularly supports high-risk, hypothesis-driven studies that may involve non-routine interventions or unlicensed products. Letters of Intent are encouraged and due 30 days prior to the full proposal deadline. All applications must be submitted by 5:00 PM local time of the applicant organization.

This funding opportunity aims to advance HIV/AIDS research by implementing human new approach methodologies (NAMs) to reduce the reliance on specific pathogen free (SPF) animal models. It emphasizes the integration of NAMs-enabled frameworks for in vitro testing while supporting essential SPF colony resources. The initiative seeks to enhance research rigor and reproducibility through innovative strategies that prioritize human-relevant models, ultimately improving HIV research outcomes and facilitating collaborative development in the field.

The SAF Technology Transfer Award honors exceptional contributions to technology transfer in forestry by an SAF member. It recognizes leaders who have significantly impacted forestry practices through innovation and quality work. The award includes a $1,000 honorarium, complimentary registration for the SAF convention, and up to $500 for travel costs. Presented at the SAF national convention, it emphasizes the importance of effective technology transfer for sustainable forest management.

The Limited Competition NOFO aims to provide ongoing support for specific pathogen-free (SPF) macaque colonies that facilitate vital HIV/AIDS research. Only recipients funded under previous ORIP-supported SPF colony announcements are eligible to apply. These breeding colonies are crucial for maintaining SPF macaques, which are free from certain viruses that could jeopardize research outcomes. The project emphasizes the genetic characterization of macaques to enhance understanding of immune responses related to HIV and SIV.

The Bob Zylstra STEM Scholarship, offered by the Grand Rapids Community Foundation, supports undergraduate students who identify as female or as students of color from West Michigan. This scholarship aims to empower students pursuing STEM majors by removing barriers to education and fostering diversity in these fields. Each year, the foundation awards scholarships ranging from $2,000 to $5,000 to help students achieve their academic and career aspirations.

The upcoming National Institute of Mental Health (NIMH) funding opportunity aims to explore the effects of HIV immunotherapies on central nervous system (CNS) outcomes. It seeks to identify mechanisms, benefits, and risks associated with these therapies, focusing on overcoming CNS-specific barriers. The initiative encourages collaborations to develop strategies for achieving sustained virologic remission and improving neurological outcomes for individuals with HIV, particularly targeting neurotoxicity and neuroinflammation.

The Cancer Prevention and Control Programs aim to eliminate cancer through collaborative efforts among state, territorial, and tribal organizations. Funded by the CDC, this program supports initiatives such as breast and cervical cancer screening, cancer control planning, and cancer surveillance. By fostering partnerships and community involvement, the program seeks to improve health outcomes and achieve the mission of 'All People Free of Cancer.' This comprehensive approach ensures that resources are effectively coordinated to address the cancer burden in communities.

Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre

Our Mission and Goals

The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).

ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:

• Subsidizing new, emerging, and underserved student theatre programs;
• Creating paths for theatre educators to develop new skills; and
• Commissioning research to showcase the value of a theatre education.

Grants for Educators & Theatre Programs

A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.

For EdTA Members

Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.

Production Grants

Show-specific financial assistance for educational theatre programs

Fiddler on the Roof Grant

The Fiddler on the Roof Grant covers performance royalties and support resources for middle or high school Thespian troupes to perform Fiddler on the Roof or Fiddler on the Roof JR. through Music Theatre International. Funders Helene and Edward Cole created the grant to help educate students and communities about Jewish heritage and culture.

The Friends Foundation for the Aging Grant supports innovative and impactful programs aimed at addressing the needs of older adults, particularly within underserved populations. This Quaker foundation prioritizes collaboration and sustainability in its funding efforts. Eligible applicants must be 501(c)(3) public charities focused on enhancing the quality of life for aging individuals. Grants are typically awarded for one year and target organizations that align with the foundation's mission and values.

The Special Wildlife Funds - Duck Stamp Grants program in Canada focuses on the development of waterfowl propagation areas specifically for the Mississippi Flyway. It supports projects in Manitoba and Saskatchewan aimed at enhancing breeding populations of migratory waterfowl. This initiative is funded through the sale of State Migratory Waterfowl Stamps and is targeted at not-for-profit organizations dedicated to the conservation and promotion of wild waterfowl, ensuring sustainable habitats and effective management practices.

The Elizabeth Taylor AIDS Foundation (ETAF) provides grants focused on HIV/AIDS care, advocacy, and education. Grants are awarded annually based on a review process, emphasizing projects that align with Ms. Taylor’s vision. Eligible organizations must have at least three years of experience in HIV/AIDS programs and can apply only once per year. ETAF prioritizes funding for direct care and prevention initiatives, while restricting support for multi-year proposals and non-HIV specific projects.

Alkermes

At Alkermes, we apply our deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders, including addiction, serious mental illness and sleep disorders. With our portfolio of marketed medicines and investigational pipeline candidates, we seek to make a meaningful difference in the way people manage these chronic diseases. Our patient-inspired science, integrated research strategy, sophisticated development capabilities and specialized commercial infrastructure enable us to pursue the development and commercialization of innovative new medicines, including those for people with conditions that have traditionally been overlooked or stigmatized.

Our greatest strengths at Alkermes are our people and our inherent empathy for patients, families and caregivers. Neurological and psychiatric disorders strike people at the core of who they are and impact many facets of their lives. We work with urgency to develop new treatment options for people living with these conditions.

Pathways APN Research Awards

The Alkermes Pathways Advanced Practice Nurse (APN) Research Awards™ program is designed to empower the advanced practice nursing community by offering funding opportunities that recognize their vital role in evidence-based care and the advancement of mental health research.

The Alkermes Pathways APN Research Awards provide opportunities for individual grants of up to $10,000 per project for licensed psychiatric-mental health nurse practitioners who are actively engaged in clinical, academic, and/or community health settings and are committed to advancing research in schizophrenia or bipolar I disorder.

The Alice M. Ditson Fund offers organizational support for summer festivals and conferences focused on contemporary American classical music. This funding opportunity encourages the appreciation of works by younger, relatively unknown American composers. Eligible applicants include performing organizations and institutions that promote artistic excellence. The Fund emphasizes supporting living composers at various career stages, ensuring a broader recognition of their contributions to classical concert music. It is crucial for applicants to align their projects with the Fund's mission of enhancing public knowledge and appreciation.