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Best Fayette County Grants for Nonprofits in Pennsylvania

Discover active funding opportunities in Fayette County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Westmoreland County, Washington County, and Greene County.

9,000+

Available grants

$2.65B

Total funding

$5K

Median grant

9,000+ grants
$2.65B total
$5K median

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9,471 Results based on applied filters

Wallerstein Foundation Grant

Wallerstein Foundation for Geriatric Life Improvement Inc.
Private
United States
Unspecified amount
The Wallerstein Foundation for Geriatric Life Improvement is dedicated to enhancing the lives of elderly individuals through targeted support for non-profit organizations. Grants focus on critical areas such as dementia care, wellness programs, and community engagement initiatives. The foundation prioritizes projects that meet the unique needs of seniors, promoting health and active lifestyles. By funding specific projects rather than general support, the foundation aims to make a meaningful impact on the quality of life for senior citizens.
Senior Services Aging / Gerontology Dementia & Alzheimer’s Disease +3 more

Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH is inviting applications for interventions aimed at enhancing cancer screening and preventive services in underserved populations. This initiative focuses on addressing barriers to healthcare access and promoting timely follow-up on abnormal findings. Collaborations with community partners are encouraged to foster effective outreach. The program particularly seeks to engage patients, clinicians, and healthcare settings in improving health equity and outcomes in cancer prevention.
Health Disparities & Social Determinants of Health Cancer / Oncology Preventative Healthcare

Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards (U01 - Clinical Trials Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites renewal applications for existing NINDS-supported clinical trial cooperative agreements (U01) that require additional time and resources. The National Institute of Neurological Disorders and Stroke (NINDS) expects applicants to request only what is necessary for trial completion, without introducing new aims. Discussions with NINDS prior to submission are encouraged. Eligible applications must be renewals of previously approved cooperative agreements under specified NIH funding announcements.
Neuroscience Neurological Diseases & Disorders Stroke

Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed) (356879)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.
Human Genome & Genetics Rare Diseases

Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This Funding Opportunity Announcement (FOA) aims to advance the identification and evaluation of candidate biomarkers for neurological and neuromuscular disorders. By facilitating the clinical development of neurotherapeutics, the FOA encourages research that includes both animal studies and preliminary human evaluations. The ultimate goal is to produce biomarkers ready for rigorous analytical and clinical validation, enhancing the effectiveness of treatments in clinical practice.
Biomedical informatics Neurological Diseases & Disorders Musculoskeletal Diseases

Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed) (356887)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Limited Competition: Basic Instrumentation Grant (BIG) Program, supported by the NIH, invites applications from institutions that have not received significant S10 funding in recent years. This program provides a minimum award of $25,000 and allows for a maximum of $350,000 to purchase specialized instruments essential for NIH-supported research. Eligible instruments include cell sorters, confocal microscopes, and more, promoting advancements in biomedical research.
Biology Health & Medicine Medical Technology, Devices, and Equipment

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) (356886)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Shared Instrumentation Grant (SIG) Program supports NIH investigators in acquiring high-cost, specialized instruments essential for research. With a minimum award of $50,000 and a maximum of $750,000, this program facilitates the purchase or upgrade of equipment like mass spectrometers and light microscopes. It encourages collaborative efforts among researchers to enhance capabilities and foster innovation in biomedical research.
Biology Health & Medicine Medical Technology, Devices, and Equipment

High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) (356883)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The High-End Instrumentation (HEI) Grant Program, funded by the NIH, supports NIH-supported investigators in acquiring high-end, specialized instruments. With a minimum award of $750,001 and a maximum of $2,000,000, this program aims to enhance research capabilities. Eligible instruments include nuclear magnetic resonance spectrometers, mass spectrometers, and advanced imaging systems, among others. Applications are due by 5:00 pm local time of the applicant organization.
Medical Technology, Devices, and Equipment Health & Medicine Biotechnology +1 more

Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed) (356888)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.
Biomedical informatics Epidemiology & Public Health Health Information Technology

Reboot Representation Grant

Reboot Representation Tech Coalition
Association/Society
United States
Unspecified amount
The Reboot Representation Tech Coalition aims to significantly increase the number of Black, Latina, and Native American women earning computing bachelor’s degrees. They invite qualified organizations to submit grant inquiries focused on recruiting and retaining these women in tech. Programs that leverage existing resources and operate across multiple regions will be prioritized, and the Coalition seeks initiatives backed by substantial research and community trust.
Computer Science & Engineering Diversity, Equity & Inclusion Women's Rights & Equality +4 more

Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program, funded by the NIH, aims to enhance the biomedical research landscape by supporting resource-limited organizations. It targets domestic institutions with limited research resources and few doctoral students in biomedical fields, promoting broader participation in research and boosting administrative capacities for sponsored programs. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submissions.
Biology Health & Medicine

Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional) (356925)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
This grant opportunity from the NIH aims to enhance mechanistic research on precision probiotic therapies through a biphasic R61/R33 award mechanism. It encourages innovative studies to identify specific biological factors influencing probiotic responses, thereby improving clinical outcomes. The program supports up to five years of research, with the initial phase focused on discovering unique host characteristics and the second phase assessing improvements in probiotic efficacy through rigorous studies.
Integrative & Alternative Health Microbiomes

Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional) (356927)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,400,000
This funding opportunity aims to advance mechanistic research for precision probiotic therapies. It invites R33 applications focused on characterizing individual differences in probiotic responses, identifying responder subgroups, and enhancing clinical outcomes. The goal is to develop strategies addressing barriers to effective probiotic use, accounting for human variability. Proposals should include innovative studies using animal models or human subjects, supported by preliminary data to test biological patterns and their effects on health outcomes.
Biology Microbiology Microbiomes

Extramural Discovery Science Accelerator Award

American Cancer Society
Association/Society
United States
Up to US $75,000
The Extramural Discovery Science Accelerator Award supports the commercialization of ongoing cancer research projects, focusing on experiments that facilitate technology validation and de-risking. Applications are accepted on a rolling basis, with a budget of up to $75,000 for one year. This award encourages independent investigators at any career stage to advance their technologies, with a strong emphasis on commercial viability and collaboration within a learning community.
Cancer / Oncology Medical Technology, Devices, and Equipment

Leukemia Exploration and Prevention Grant Program (LEAP) - Team Award

American Cancer Society
Association/Society
United States
Up to US $1,720,000
The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.
Leukemia

Leukemia Exploration and Prevention Grant Program (LEAP) - Research Scholar Grant

American Cancer Society
Association/Society
United States
Up to US $860,000
The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.
Leukemia

Green Chemistry Student Chapter Award

American Chemical Society
Association/Society
United States
Unspecified amount
The Green Chemistry Student Chapter Award recognizes ACS student chapters for their commitment to green chemistry initiatives. This award highlights the importance of green chemistry in education, encouraging students to engage in activities that promote sustainability. Eligible chapters must submit detailed summaries of at least three green chemistry projects, demonstrating their understanding of the principles and practices that contribute to a more sustainable future.
Chemistry

USF: Community Impact Grant

Usa Swimming Foundation
Private
United States
Up to US $5,000
The USF Community Impact Grant, established by USA Swimming and the USA Swimming Foundation, aims to enhance competitive opportunities in swimming clubs. Grants of up to $5,000 are available for registered USA Swimming clubs committed to fostering community engagement and collaboration. Eligible clubs can renew their grant for up to three years, promoting diverse access to swimming programs. This initiative particularly supports clubs that partner with educational or public entities and those led by women or minorities.
Swimming

Robert L. Wesley Award

Skidmore, Owings and Merrill Foundation
Private
United States
US $10,000
The Robert L. Wesley Award, established by the SOM Foundation in 2020, honors BIPOC undergraduate students in architecture and related fields. Each year, three students receive a $10,000 award along with mentorship from leading BIPOC professionals. This initiative aims to support the educational journey of these students, enabling them to pursue their aspirations in design without financial constraints. The award fosters a community of support, encouraging the next generation of licensed architects to thrive.
Architecture Indigenous Sovereignty & Rights

Emerging Global Leader Award (K43 Independent Clinical Trial Required) (356724)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
Afghanistan, Albania +125 more
Approximately US $140,000
The Emerging Global Leader Award (K43) offers essential research support and protected time for early career scientists in low- and middle-income countries. This program, aligned with NIH's clinical trials policy, aims to cultivate independent research careers by providing mentorship and funding over three to five years. Eligible candidates must hold a junior faculty position at an accredited LMIC institution, fostering the growth of research capacity in their regions.
Aging / Gerontology Cardiovascular Diseases & Systems Hematological Systems +15 more

Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed) (356723)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
Afghanistan, Albania +125 more
Approximately US $140,000
The Fogarty Emerging Global Leader Award supports early career research scientists from low- or middle-income countries (LMIC) by providing research funding and mentored career development for three to five years. This program encourages LMIC scientists in health-related fields to develop projects aligned with their country's health priorities, fostering independent research careers within their institutions. Applications are welcomed from junior faculty members, enhancing global health research and capacity in LMICs.
Cancer / Oncology Neurological Diseases & Disorders Mental Health & Psychiatric Diseases +14 more

NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional) (356763)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The NIDCD Early Career Research (ECR) Award (R21) supports new scientists establishing independent research careers in areas related to hearing, balance, smell, taste, voice, speech, or language. This grant encourages innovative projects such as secondary data analysis, small research initiatives, and technology development, aiming to generate preliminary data for future R01 applications. All applications must be submitted by 5:00 PM local time of the applicant organization.
Hearing Disorders & Audiology Communication Disorders

Rise for Education Grant Program

Rise Gardens
Corporate
United States
Unspecified amount in in-kind support
The Rise for Education Grant Program offers funding for hydroponic classroom gardens that enhance STEM education and nutrition. This initiative encourages hands-on learning, integrating STEM and arts through practical gardening projects. Eligible applicants include schools, homeschooling families, and educational organizations. The program fosters community building and entrepreneurship via activities like Farmer's Markets, while boosting student engagement and developing essential skills. By implementing this program, educators can create an engaging and interactive learning environment year-round.
Horticulture & Gardening

All Kids Play: Youth Sports Grant - Organization

All Kids Play
Private
United States
Unspecified amount
The All Kids Play: Youth Sports Grant aims to support families and community-based organizations in low-income areas, ensuring access to recreational sports for children in grades K-12. This grant assists those who struggle to afford youth sports, providing essential funding on a first-come, first-served basis. Eligible organizations must demonstrate budget constraints and operate in areas with high low-income student percentages, promoting inclusivity in youth sports participation.
Youth Services Sports & Athletics Education - K through 12

American-Made Promoting Registration of Inverters and Modules with Ecolabel (PRIME) Prize

United States Department of Energy (DOE)
Federal Government
United States
Up to US $450,000
The American-Made Promoting Registration of Inverters and Modules with Ecolabel (PRIME) Prize, backed by the U.S. Department of Energy, offers $2.7 million to enhance the registration of solar PV modules and inverters via the EPEAT ecolabel. This initiative encourages manufacturers to meet EPEAT standards, thus appealing to environmentally conscious buyers. With two phases, the competition aims to boost sustainable practices as the U.S. increases solar adoption in various sectors.
Renewable/Sustainable Energy Solar Energy

WAEF Scholarships - Danna Gebbers Guzman Memorial

Washington Apple Education Foundation
Private
United States
Unspecified amount
The WAEF Scholarships, supported by the Washington Apple Education Foundation, offer over $1 million in educational awards to more than 300 students this year. These scholarships are primarily for individuals with ties to the tree fruit industry in Washington, with a special focus on the Danna Gebbers Guzman Memorial Scholarship, aimed at nursing students. Eligible recipients can use the funds at accredited institutions with nursing programs.
Agricultural Crops Nursing

Fayette County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all Fayette County grants recommended for your specific programs in Pennsylvania.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Pennsylvania

Average Grant Size

What's the typical amount funded for Pennsylvania?

Grants are most commonly $120,832.

$120,832

Total Number of Grants

What's the total number of grants in Fayette County Grants for Nonprofits year over year?

In 2024, funders in Pennsylvania awarded a total of 114,767 grants.

2022 101,760

2023 105,380

2024 114,767

Top Grant Focus Areas

Among all the Fayette County Grants for Nonprofits given out in Pennsylvania, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Fayette County Grants for Nonprofits changing over time?

Funding has increased by 39.90%.

2022 $9,486,595,381

2023 $9,869,112,363
4.03%

2024 $13,806,751,647
39.90%

Pennsylvania Counties That Receive the Most Funding

How does grant funding vary by county?

Montgomery County, Philadelphia County, and Allegheny County receive the most funding.

County Total Grant Funding in 2024
Montgomery County $11,058,341,664
Philadelphia County $2,487,099,923
Allegheny County $1,915,534,930
Chester County $846,675,579
Centre County $563,407,306