Best Mifflin County Grants for Nonprofits in Pennsylvania

501(c)(3) pet welfare organizations in Mifflin County, Pennsylvania that promote domestic animal and pet welfare can apply for Nestlé Purina’s support. Funding can help with capacity building, capital improvements, and program or spay/neuter costs, and eligibility is limited to U.S. groups within 50 miles of Purina facilities or its St. Louis headquarters.

Current or recent Regional Foundation grantees facing urgent disaster or crisis-related needs in Mifflin County, Pennsylvania can request short-term responsive funding for unforeseen tactical or strategic challenges. With a mission to back partners during critical moments, Regional Foundation provides up to US $25,000 for emergencies like natural disasters, emergent policy threats, or disruptive organizational events.

Nonprofit 501(c)(3) organizations in Mifflin County, Pennsylvania can seek US $500 - US $5,000 to enhance local quality of life through programs in health, education, social services, culture, environment, business development, and community beautification. Grants from Charles B. Degenstein Foundation support well-defined projects within 75 miles of Sunbury that show strong community backing.

Nonprofits and conservation partners restoring forests and streams in Mifflin County, Pennsylvania can apply for US $75,000 - US $500,000 to improve habitat for native birds and aquatic species. The National Fish and Wildlife Foundation’s Central Appalachia Habitat Stewardship Program funds voluntary forest management, riparian restoration, barrier removal, and landowner engagement to enhance wildlife populations and freshwater health.

State and local agencies, local governing boards, nonprofits, tribes, and higher education institutions in Mifflin County, Pennsylvania can seek funding to improve critical infrastructure and support business and workforce development. With a mission to strengthen Appalachian communities, Appalachian Regional Commission provides flexible, community-driven investments in water and wastewater systems, transportation, broadband, entrepreneurship, worker training, and related economic development projects.

Nonprofits and public entities in eligible Appalachian counties, including Mifflin County, Pennsylvania, can apply for Appalachian Regional Commission’s ARISE grants, offering up to US $10,000,000 for multi-state planning and implementation projects that strengthen regional economies. Funding supports economic development, workforce readiness, community revitalization, and tourism initiatives that span multiple Appalachian states.

2026 Medication-Assisted Substance Use Treatment Grant Program 

Overview:

This is a noncompetitive funding announcement open to the 61 counties in Pennsylvania with a county jail. The Pennsylvania Commission on Crime and Delinquency (PCCD) is now accepting applications for funding under the 2026 Medication-Assisted Substance Use Treatment Grant Program. The primary purpose of this funding is to support counties seeking to increase opportunities to provide Medication-Assisted Treatment (MAT), in combination with comprehensive substance use disorder treatment, to eligible offenders who meet the clinical criteria for an opioid use disorder or an alcohol use disorder, as determined by a physician, while incarcerated and upon release from a county jail. For purposes of this funding announcement, the term "Medication-Assisted Treatment" means the use of United States Food and Drug Administration-approved medications (buprenorphine, methadone, and naltrexone/Vivitrol), together with nonmedication treatment, as clinically indicated, to treat substance use disorders, including opioid use disorders and alcohol use disorders. Administration of these medications along with comprehensive substance use disorder treatment will allow newly released participants to focus on immediate reentry needs.

Funded counties will adhere to program activities and requirements as discussed in this funding announcement and work collaboratively with local and state partners to ensure effective program operations and successful project outcomes.

Successful projects will allow county jails to better equip reentrants as they transition to the community.

The Chesapeake Bay Green Streets, Green Jobs, Green Towns (G3) Grant Program, funded by the EPA and Chesapeake Bay Trust, supports innovative green infrastructure projects enhancing community livability. With funding opportunities ranging from conceptual plans to full project implementation, this program aims to reduce stormwater runoff, improve urban green spaces, and boost local water health within the Chesapeake Bay watershed. Eligible locations include parts of Delaware, Maryland, Pennsylvania, and Virginia, as well as New York.

The Santander Charitable Sponsorship Program focuses on supporting low- to moderate-income communities primarily in the Northeast and Florida. With a commitment of $100 million in charitable giving, the program addresses key community development needs, including affordable housing, job creation, financial education, and disaster relief. Eligible organizations must have IRS 501(c)(3) status or be public agencies, demonstrating capacity to meet community needs. Unsolicited applications are not accepted.

The Chesapeake Bay Small Watershed Grants, offered by the National Fish and Wildlife Foundation (NFWF) in collaboration with the EPA, aim to enhance water quality and restore vital habitats in the Chesapeake Bay watershed. Funding is available through two programs: SWG Implementation grants for direct on-the-ground actions, and SWG Planning and Technical Assistance grants to support community-based efforts. Projects must align with specific program priorities to qualify for funding.

Nonprofit and conservation organizations reducing nutrient and sediment pollution in the Chesapeake Bay watershed, including Mifflin County, Pennsylvania, can seek funding for water quality, freshwater conservation, and habitat restoration projects. National Fish and Wildlife Foundation provides up to US $2,000,000 for innovative efforts that improve rivers, streams, and related ecosystems in eligible counties.

Nonprofit 501(c)(3) public charities in Mifflin County, Pennsylvania working to expand access to abortion and contraception can apply for support from the Educational Foundation of America. The Reproductive Health & Justice program funds litigation, direct support for providers, abortion funds, and communications and advocacy efforts, with a particular emphasis on Appalachian communities.

Nonprofit 501(c)(3) organizations serving Mifflin County, Pennsylvania can apply for grants supporting charitable, scientific, literary, educational, and cultural programs. Grants from Josiah W & Bessie H Kline Foundation help South Central Pennsylvania nonprofits, with emphasis on Dauphin and Cumberland Counties, that work to improve individuals, families, and communities.

The Highmark Foundation provides high-impact grants aimed at enhancing community health in Pennsylvania and West Virginia. It supports evidence-based programs that address critical health issues, including chronic diseases, family health, and access to care. The Foundation prioritizes initiatives that demonstrate sustainable solutions and collaboration with community partners. By funding diverse health-related projects, it aims to improve the well-being of underserved populations, ensuring that vital health interventions reach those in need.

501(c)(3) nonprofits addressing hunger relief and food access in eligible rural East and West region counties can apply for Land O'Lakes Foundation’s Region Grants, with awards of US $1,000 - US $20,000 for local programs. Food banks, pantries, meal services, school meal programs, and community gardens in rural Pennsylvania, including nearby areas to Mifflin County, may benefit.

Nonprofit and conservation partnerships restoring and connecting fish and wildlife habitat in Mifflin County, Pennsylvania can seek funding to improve conditions for at-risk and federally listed species. The National Fish and Wildlife Foundation’s Chesapeake WILD Collaborative Conservation track offers up to US $200,000 to support landscape-scale habitat restoration, water quality improvements, and coordinated conservation efforts.

U.S.-based 501(c)(3) pet welfare organizations hosting cat and dog welfare events can request Nestlé Purina’s event sponsorship support, including monetary aid, pet food, litter samples, or giveaway items. Eligible events must occur within 50 miles of St. Louis or a Purina manufacturing location, so Mifflin County, Pennsylvania nonprofits may be eligible if they meet this requirement and apply six months in advance.

The Region Grants Open Grant Round: Community Vitality, supported by Land O'Lakes Foundation, aims to enhance the vibrancy of dairy communities in the East and West Regions. With a total investment of $500,000 annually, grants ranging from $1,000 to $20,000 are available for organizations focused on rural development, education, and community resources. Eligible applicants must have a 501c3 status and serve specific geographic areas, ensuring support reaches those in need.

Focused on habitat and wildlife conservation, National Fish and Wildlife Foundation invites Mifflin County, Pennsylvania nonprofits to apply for Chesapeake WILD implementation grants supporting on-the-ground restoration and stewardship projects. Eligible projects must enhance fish and wildlife habitats, improve water quality, and build climate resilience within the Chesapeake Bay watershed, with awards ranging from US $75,000 - US $500,000.

Nonprofit and conservation partners in eligible Chesapeake watershed areas, including parts of Pennsylvania, can seek planning and technical assistance funding to improve and connect habitats for at-risk and federally listed species. National Fish and Wildlife Foundation offers grants up to US $75,000 for community-based assessment, planning, design, and related technical assistance activities.

Nonprofit and public partnerships in Mifflin County, Pennsylvania working on economic diversification, workforce development, job creation, or broadband can seek up to US $2,500,000 for planning or implementation projects. With a mission to revitalize coal-impacted Appalachian communities, Appalachian Regional Commission supports regional, stakeholder-driven strategies that build competitive industries and high-quality employment opportunities.

Nonprofit organizations serving Mifflin County, Pennsylvania can seek competitive funding for community, health, education, arts, animal welfare, and human services programs through Centre County Community Foundation’s Field-of-Interest grants. Focused on donor-designated causes and geographies, these funds may support work with children, low-income residents, people with disabilities, and other local populations in need.

Grants from 1994 Charles B. Degenstein Foundation help Mifflin County, Pennsylvania 501(c)(3) nonprofits fund education, healthcare, environmental, and other strategic regional projects. Organizations within 75 miles of Sunbury can request more than US $10,000 for well-defined programs, especially when additional community or co-funding supports the project’s impact.

Focused on food access and hunger, Central Pennsylvania Food Bank invites Mifflin County, Pennsylvania nonprofits and school or community partners to participate in its youth nutrition programs. Organizations can collaborate on school pantries, Kids Cafe sites, BackPack food distributions, and summer meal programs to provide consistent, nutritious food to children and their families.

Focused on environmental conservation, Weconservepa invites Mifflin County, Pennsylvania nonprofits to apply for the Healing the Planet Grant Program. Eligible community projects use native trees, shrubs, and plants to improve local air and water quality, public health, and overall quality of life, with awards up to US $4,000.

Nonprofit 501(c)(3) organizations or those with a fiscal sponsor serving residents of Mifflin County, Pennsylvania can apply for The Foundation for Enhancing Communities’ Greater Harrisburg Foundation Benjamin Franklin Trust Fund, offering up to US $1,700 for one-year community services projects. Programs must enhance knowledge, quality of life, or inspire positive outcomes for local individuals and families.

The Louis J. Appell, Jr., Preservation Fund for Central Pennsylvania supports local preservation efforts by funding maintenance and restoration of historic places in specific Pennsylvania counties. Eligible applicants include public agencies and non-profit organizations, with a matching requirement for grant amounts. Grants aim to enhance public awareness of the region's heritage while addressing preservation challenges through technical assistance and financial support for essential restoration activities.