Best Large Grants for Nonprofit Organizations in Indiana

The Zyne Family Foundation Grant aims to enhance and support Catholic faith-based organizations and other 501(c)(3) nonprofits dedicated to education, medical research, and family values. The foundation's mission focuses on making a direct impact on individuals' daily lives, ensuring that these initiatives can thrive both now and in the future, promoting community well-being and development.

The Space Technology Research, Development, Demonstration, and Infusion (SpaceTech REDDI-2026) initiative by NASA aims to advance transformational space technologies to meet critical stakeholder needs. This umbrella solicitation for FY 2026 will invite proposals across various technology topics, promoting innovation and competitiveness in the U.S. space sector. With a focus on economic growth and fostering a strong aerospace community, STMD supports ideas from diverse innovators nationwide.

American Chemical Society

The American Chemical Society (ACS) is a non-profit organization founded in 1876 and chartered by the U.S. Congress. ACS is committed to improving all lives through the transforming power of chemistry. Our mission is to advance scientific knowledge, empower a global community, and champion scientific integrity. Our vision is a world built on science.

What We Do

More than 145 years after our founding, we remain a champion for chemistry, its practitioners and our global community of members.

We’re recognized as a leading publisher of authoritative scientific information. Our 80+ peer-reviewed journals are ranked the “most-trusted, most-cited and most-read.”

We empower our members to advance chemistry, elevate their career potential, expand their networks, inspire future generations, collaborate globally and build communities that provide scientific solutions.

We provide broader networks that facilitate connections and open doors in a way no other professional organization can match!

ACS Graduate Student Success Grant

Purpose

To support graduate students (M.S. and Ph.D.), within one year of degree completion, whose education and training were disrupted due to termination or cancellation of research grants. Funding will be given to the Principal Investigator (PI) of the lab. This one-year award, the ACS Graduate Student Success Grant, will enable students to complete their degree programs. The grant seeks to lower the risk of a declining number of U.S.-trained chemists with advanced degrees, thereby preserving the strength and continuity of the scientific community.

Description

The ACS Graduate Student Success Grant provides $25,000 for one year to a faculty member who lost funding after October 1, 2024, that supports one or more graduate students. The award will also connect supported graduate students to ACS career development resources and programming to catalyze their transition into the workforce.

The grant funds will be awarded to exclusively support graduate students (M.S. and Ph.D.) who are within one year of degree completion and in need of funds to ensure degree completion. This grant supports currently enrolled graduate students who conduct research related to the chemical sciences in a department at a U.S.-based institution of higher education. Each institution of higher education can receive a maximum of one ACS Graduate Student Success Grant.

Applicant must provide a signed letter on institutional letterhead from the Vice President of Research (or equivalent), confirming the institution’s support, including the following:

• The PI’s loss of funding due to grant termination or cancellation after October 1, 2024.
• The names, current academic status, and anticipated graduation time of the impacted graduate students.

American Physical Society

The American Physical Society is a nonprofit membership organization working to advance physics by fostering a vibrant, inclusive, and global community dedicated to science and society. APS represents more than 50,000 members, including physicists in academia, national laboratories, and industry in the United States and around the world.

APS Honors recognizes and celebrates the accomplishments of the global physics community. Guided by our core values, APS Honors encourages nominations that reflect the full range of talent, distinction, and experience in our field, and supports broad canvassing for professional achievement across diverse backgrounds, perspectives, and expertise.

Improving Undergraduate Physics Education (IUPE) Award

The American Physical Society's (APS) Committee on Education (COE) seeks to recognize improvement in undergraduate physics education and support effective practices in education at the undergraduate level with the COE Award for Improving Undergraduate Physics Education.

This award will recognize up to three undergraduate physics programs, organizations, alliances, and networks each year and will focus on the entire undergraduate physics institution, organization, alliance, and/or network, rather than individual members of a department.

• Applicants may submit only one application per year.
• We encourage applicants not recognized in a particular year, to submit new applications after the award period has ended.
• To encourage broad participation and to motivate programs, organizations, alliances, and networks to commit to sustained improvement and achievement, awardees may submit new applications after three years.

About PLTW Computer SciencePLTW Computer Science students are technology trailblazers who are empowered through transportable skills and prepared to start their career, whether that is in computer science or not.

Lockheed Martin has committed funds to support PLTW grants to schools interested in adding PLTW.

Since 2007, Lockheed Martin has partnered with PLTW to address the nation's critical need for future engineers, computer scientists, and math- and science-trained professionals, and to equip all students with the knowledge and skills they need to thrive. Lockheed Martin supports PLTW programs in school districts across the nation and has contributed to the development of PLTW's middle school and high school courses focused on aerospace engineering and flight. Since the first school district partnership in 2014, over 855 PLTW programs have been implemented and more than 145,328 students have gained access to PLTW.Program Requirements:

• Grantee must use their grant funds to expand their existing PLTW Computer Science program.
  • Example expansion activities include but are not limited to adding an additional PLTW Computer Science course not previously offered,
  • and/or adding additional class periods of an existing PLTW Computer Science courses previously offered,
  • and/or training additional teachers in PLTW Computer Science courses for the 2027-2028 academic year. 

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

The Kenneth A. Scott Charitable Trust offers grants aimed at enhancing the lives of animals in the Ohio/Great Lakes region. It prioritizes projects that foster animal adoption, behavior training, and humane education. Eligible organizations must be 501(c)(3) certified and demonstrate a commitment to animal welfare. The Trust seeks innovative, collaborative initiatives that significantly improve the well-being of animals, particularly in underserved communities, ensuring a high quality of life for both individual animals and larger populations.

Artis offers exhibition grants to support contemporary artists from Israel, aiming to promote critical dialogue and cultural exchange in international settings. These grants facilitate presentations at renowned organizations globally, focusing on innovative and impactful projects that engage with pressing social and environmental issues. The program prioritizes proposals that demonstrate curatorial ambition and artistic experimentation, fostering collaboration across diverse disciplines. Artis is committed to shaping a sustainable art world while addressing urgent global challenges through artistic practice.

The NRC Research Associateship Grant Program, managed by the National Academies of Sciences, Engineering, and Medicine, provides prestigious research opportunities for postdoctoral and senior scientists at federal laboratories. This program promotes scientific excellence through mentorship and access to advanced facilities. Eligible candidates must hold a relevant doctorate and demonstrate significant research potential. With annual deadlines on February 1, May 1, August 1, and November 1, this initiative aims to enhance the career development of promising researchers.

Ann Lane Gates Scholarship Fund

Established by Ann Lane Gates to provide scholarships for Project GRAD Akron Public Schools students.

Amount:

• Varies $500-$1,500

Number of awards:

• Varies

Renewal:

• Renewable for three additional years. Must maintain a minimum 2.5 GPA, continue to pursue a degree in education, and reapply annually by submission of a new application.

The Classroom Education Grants provide funding for innovative projects that stimulate learning and help educators meet state standards. Individual teachers and collaborations can apply, promoting impactful projects within Huntington County schools. Administrators can also seek funding for school-wide initiatives that go beyond traditional budgets. This grant encourages creativity and collaboration, aiming to make a significant difference in the educational experiences of students.

Bengier Foundation

After lots of hard work and more than a bit of luck, Gary and Cynthia were able to retire from professional business careers at an early age. They decided then to try to give back a little to their community and to others less lucky than they. So the Bengier Foundation was formed in 2004 to give a helping hand to bright, hardworking young people who need a little help to find their own success.

One of our goals is to help – in a small way – to focus attention on the need to increase our American educational capital. The dropout rate statistics are shocking. We must do more to help the next generation prepare for the increasing demands of our ever-more sophisticated information economy. The Bengier Foundation believes that we must give everyone a chance to achieve their potential.

Bengier Foundation Grants

The foundation's mission is to provide educational experiences that motivate, broaden and qualify bright, hard working young people who have limited means and limited opportunities to enlarge their expectations of what they can accomplish in life.

• By motivate we mean to change a young person’s expectations about themself, by providing experiences which pique their interest, or that let them see themself in a role or career that they never previously imagined.
• By broaden we mean to allow a young person to have experiences that broaden their perspective of the world or cause them to view it and their role in it differently.
• By qualify we mean to help a young person gain the experiences and education that will allow them to succeed in college and in life.

Barbara McDowell Social Justice Center Inc.

The Barbara McDowell Social Justice Center litigates, educates, advocates, and provides grants to nonprofits to eradicate social injustices. 

We pursue litigation through our own efforts as well as funding others in the following fifteen issue areas: Access to Benefits, Children’s Rights, Disability Rights, Discrimination, Domestic Violence, Due Process, Environmental Justice, Healthcare, Homelessness, Housing, Native American Rights, Prisoners’ Rights, Refugee and Immigration Rights, Voting Rights, and Veterans’ Rights.

Barbara McDowell Social Justice Center Grant

We make grants to organizations that undertake systemic social justice litigation across fifteen issue areas. The Center funds litigation matters that are consistent with our namesake Barbara McDowell’s past legal efforts and her beliefs regarding social justice.

Applications must be for a specific social justice legal case, including the filing of an appeal. Grant funds are to be used only for attorney time charges and litigation expenses related to the specific case for which an organization is applying to be funded. 

The Stanley C. Israel Regional Award for Advancing Diversity in the Chemical Sciences recognizes individuals or institutions promoting inclusiveness in the chemical sciences. This award includes a medal, a $1,250 grant, and reimbursement for travel expenses up to $1,500 for attending the ACS regional meeting where the award is presented. Eligible nominees must foster programs that increase participation from diverse groups in the chemical enterprise.

The AJ Muste Foundation's Rapid Response Grants support U.S.-based organizations engaged in grassroots activism for social justice. These grants, up to $5,000, are aimed at addressing immediate needs of groups fighting for equality and liberation. The funding is designed for unexpected opportunities and emergencies, promoting powerful organizing efforts. The foundation prioritizes groups lacking traditional funding sources and those focused on systemic change rather than individual support.

The Limited Competition Small Grant Program for ORIP SERCA K01 Recipients provides funding to early-stage veterinary scientists to enhance their research capabilities and transition to independent investigator status. This initiative addresses challenges faced by these researchers, including reliance on funding from senior investigators. Grants support pilot studies, secondary data analysis, and development of research methodologies, aiming to foster independence within a two-year timeframe without funding clinical trials.

Helen Frankenthaler Foundation Inc

The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.

Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.

Visual Arts & Education Grant

The Helen Frankenthaler Foundation supports public engagement with the visual arts through philanthropic, educational, curatorial, and research initiatives. It has expanded its grantmaking to sustain museums and visual arts institutions, supporting exhibitions, scholarship, and education across the field. The Foundation’s grantmaking priorities are currently organized across three areas:

• Climate Action and Sustainability
• Cultural Resilience
• Visual Arts & Education
  • Project-based support for exhibitions, publications, public programs, and academic initiatives that advance the presentation, study, and interpretation of the visual arts.
  • The Foundation supports discrete, institutionally grounded projects that advance the presentation, study, and understanding of the visual arts. Competitive proposals typically include:
    • Exhibitions, publications, and public programs focused on modern and contemporary art
    • Projects that expand access to collections, archives, and curatorial research
    • Academic and institutional initiatives in art history, studio practice, visual studies, museum and curatorial studies, conservation, and related areas of scholarship and teaching—particularly those involving university museums, galleries, and special collections
    • Conferences, programs, or initiatives led by professional organizations whose missions address the visual arts
    • Exhibitions and scholarly or public programs related to the 2028 centennial of Helen Frankenthaler
    • Projects must be clearly defined in scope, duration, and outcomes, and supported by appropriate institutional capacity. Requests for Visual Arts & Education funds should not be framed as general operating support. 

This funding opportunity from the NIH encourages groundbreaking research to enhance, develop, and preserve animal models and related biological materials for studies impacting human health. The program seeks innovative methodologies that can improve the diagnosis and management of diseases affecting animal use in biomedical research. Projects must demonstrate relevance across multiple NIH Institutes to align with broader research goals, emphasizing diverse body systems and disease categories.

American Society of Civil Engineers 

The American Society of Civil Engineers represents more than 160,000 members of the civil engineering profession in 177 countries. Founded in 1852, ASCE is the nation’s oldest national civil engineering society.

ASCE stands at the forefront of a profession that plans, designs, constructs, and operates society’s economic and social engine – the built environment – while protecting and restoring the natural environment.

G. B. Mann Scholarship

All scholarships are awarded on an equal opportunity basis to current high school senior students who attend school in the Dallas Branch region (Collin, Cooke, Dallas, Denton, Ellis, Kaufman, Navarro, and Rockwall Counties) and who will be attending an institution of higher learning in the 2026 Fall Semester in pursuit of a degree in Civil Engineering.

About G. B. Mann

The (Dallas) Branch Scholarship Fund was established in the early 90s when David Schnurbusch was the Branch president. In 1993, the Fund received a large boost from George Boley Mann, when he contributed a large sum of his retirement investments to the Fund. Numerous Dallas area high school and college students have benefited from his large and kind endowment. He did not want any publicity for this contribution.

An ASCE Past President and Life Member, Mr. Mann received a degree in Civil Engineering from SMU. During WWII he worked in Ordinance Department at Aberdeen Proving Grounds in Maryland. He retired from Texas Department of Transportation after 34 years of service. He was active in ASCE and NSPE. He contributed to the construction of numerous Texas highways. He mentored many young engineers.

The National Library of Medicine (NLM) is seeking applications to establish Regional Medical Libraries within the Network of the National Library of Medicine (NNLM). Since 1965, the NNLM has enhanced public health information access through partnerships with libraries and health organizations. The initiative aims to improve community engagement, disseminate NIH research findings, and foster collaborations to promote health literacy and access to biomedical data, thereby supporting local clinical research efforts.

The FORUM Credit Union Foundation offers educator grants to enhance educational opportunities in Marion, Hamilton, Johnson, Boone, Hendricks, and Hancock counties. Each educator can receive up to $3,000 for classroom projects, supplies, and supplemental learning experiences, with a total of $30,000 allocated annually. Eligible applicants include K-12 teachers and administrators who are FORUM members in good standing. Preference is given to equitable distribution of grants across service areas.

The Kenneth A. Scott Charitable Trust Grants focus on enhancing the quality of life for companion animals and native wildlife. This private foundation supports innovative projects that go beyond basic care, ensuring the well-being of homeless and abused animals. Eligible organizations must have a 501(c)(3) status and be located in specific states, including Ohio and parts of Indiana and Michigan. The Trust emphasizes humane treatment and sustainable funding for animal welfare initiatives.

The Remote Biomarker Measurements in Microphysiological Systems Grant seeks innovative proposals to enhance remote biomarker analysis technologies for microphysiological systems, crucial for deep space missions. It prioritizes non-invasive, adaptable methods that allow for continuous monitoring of biomarkers without sample return. This initiative aims to advance personalized healthcare and biological research, addressing astronaut health in challenging environments. Eligible entities include U.S. institutions and collaborations with foreign entities under specific conditions.

Westfield Education Foundation

The Foundation was established in 1986 to assist with funding that would enrich the opportunities for our Westfield community. 

The mission of the Westfield Education Foundation is to work alongside Westfield Washington Schools and the Westfield community to empower and invest in our students and staff.

Rock Strong Award

The Westfield Education Foundation and Everwise Credit Union proudly announce a staff appreciation initiative: the Rock Strong Award! This is a quarterly award, given out at each school plus operations and student support programs, to recognize teachers, instructional assistants, instructional coaches, building secretaries, bus drivers, substitute teachers, food service staff, and operations staff for the great work they do for our children and our community!

Each quarter, all schools plus operations and student support programs (BAC/TOTS/All Aboard) will review nominations from staff, students, families, and the community and select someone representing its values and culture to receive the Rock Strong Award. Westfield Education Foundation and Everwise Credit Union will present the award winners with a commemorative plaque and a $50 Amazon gift card as a way to show appreciation for all that they do.

What it means to be Rock Strong can look different, but nominees should display dedication to students, staff and the Westfield community. 

If you would like to nominate someone for the Rock Strong award, please fill out the nomination form. 

John A. & Louise V. Maslin Scholarship

Essay:

• On the topic “The Importance of Art, Science or Math in Society.”

Award:

• One time award of $1,000.

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Richard and Mary Krauland Scholarship

This scholarship was established to provide scholarship funding to pursue a career in math or engineering.

Scholarship Details

• Available to High School Seniors
• Nonrenewable

All ACCF Scholarships are merit based.

American Chemical Society

The American Chemical Society (ACS) is a non-profit organization founded in 1876 and chartered by the U.S. Congress. ACS is committed to improving all lives through the transforming power of chemistry. Our mission is to advance scientific knowledge, empower a global community, and champion scientific integrity. Our vision is a world built on science.

What We Do

More than 145 years after our founding, we remain a champion for chemistry, its practitioners and our global community of members.

We’re recognized as a leading publisher of authoritative scientific information. Our 80+ peer-reviewed journals are ranked the “most-trusted, most-cited and most-read.”

We empower our members to advance chemistry, elevate their career potential, expand their networks, inspire future generations, collaborate globally and build communities that provide scientific solutions.

We provide broader networks that facilitate connections and open doors in a way no other professional organization can match!

ACS Catalyst Scholarship

Description

The ACS Catalyst Scholarship is an education initiative designed to support undergraduate students pursuing chemistry or chemistry-related fields. This scholarship offers support to undergraduate students who demonstrate financial need or hardship. This program provides $10,000 in funding, with the possibility of renewal in future years, to help students continue their academic journey.

Must plan to pursue a career in the chemical sciences.

Funding for this scholarship is paid directly to accredited colleges or universities to cover essential educational expenses, such as tuition, fees, and books.

The scholarships and fellowships provide recipients with the opportunity to attend and explore the operation of the field at the NRPA Annual Conference. A primary focus is to inspire future participation and leadership in NRPA and to develop professional contacts with leadership and members from around the nation. Recipients receive complimentary NRPA Annual Conference registration and a travel stipend.

Young Professional Fellowships

The fellowship provides selected young professionals (up to 4) with the opportunity to explore the operation of NRPA and its governing bodies at the NRPA Annual Conference through the support of Sourcewell. Participants will meet with mentors, be recognized at the awards ceremony and attend various conference sessions and meetings. A primary focus of the program is to inspire future participation and leadership in NRPA and to develop professional contacts.