Best Unrestricted Grants for Nonprofits in Indiana

Foundations of East Chicago offers General Operating Grants to support local nonprofits and agencies improving community quality of life. Eligible organizations must be 501(c)3 entities based in East Chicago, with funding for operational expenses from January 1 to August 31, 2026. The grant covers daily costs such as utilities, office supplies, and maintenance, ensuring community-focused initiatives are supported while adhering to strict eligibility criteria.

The McGraw Foundation offers annual grants to not-for-profit organizations, primarily in the greater Chicago area, focusing on education, conservation, and human services. Grant amounts typically range from $2,000 to $10,000, with larger grants available for particularly impactful projects. While supporting diverse initiatives, the Foundation does not fund individuals or specific events. Organizations must be tax-exempt under IRS regulations to qualify for funding. The Foundation encourages innovative approaches and partnerships in grant applications.

The Foundations of East Chicago provides annual program grants to support initiatives that enhance education, health, safety, and community enrichment. Eligible applicants must be recognized 501(c)(3) agencies in good standing. The grants focus on measurable outcomes and operational plans, prioritizing educational advancement, health awareness, and community safety. Notably, FEC does not fund speaker fees, conferences, landscaping, or general operational costs. This initiative aims to improve the quality of life in East Chicago by supporting impactful community programs.

The Cancer Center Community Outreach and Engagement Pilot Projects RFA invites proposals focused on the impact of demographics, social determinants of health, and behaviors on cancer risk and treatment. Special attention is given to high-incidence cancers in Indiana, aiming to reduce cancer's burden. Funding is available for one year with a maximum budget of $50,000, fostering innovative research to enhance community health and cancer survivorship.

The AWWA Scholarship Program, specifically the Dr. Philip C. Singer Scholarship, honors a graduate student dedicated to advancing research in drinking water quality, environmental science, and public health. Established in 2020 by the American Water Works Association, this $3,000 scholarship aims to support innovative research that addresses pressing challenges in the water industry. By investing in future leaders, AWWA reinforces its commitment to ensuring safe and sustainable water for all.

The Community Possible Grant Program by U.S. Bank aims to foster economic and workforce advancement, as well as safe and affordable housing. By partnering with 501(c)(3) nonprofit organizations, the program seeks to drive lasting change within communities through collaborative grantmaking. Priority is given to organizations that promote diversity, equity, and inclusion, and that address multiple pillars of work, home, and play. This initiative reflects U.S. Bank's commitment to creating a more equitable society.

The Environment Pillar Award by Honda supports nonprofit organizations and schools in the U.S. focused on sustainability. Grants aim to reduce environmental impact through programs in decarbonization, clean energy, and efficient resource use. Eligible projects must align with Honda's mission and primarily benefit communities where Honda associates live and work. Organizations can apply for up to two grants, provided they meet specific eligibility criteria, including tax-exempt status under the IRS.

The KeyBank Foundation Grants support nonprofit organizations focused on enhancing communities through education, workforce development, and affordable housing. Founded in 1969, the Foundation prioritizes diversity, financial capability, and sustainability. Their grants aim to empower individuals for success by improving access to resources, fostering economic inclusion, and creating safe environments. By partnering with community organizations, KeyBank Foundation seeks to make a measurable impact and ensure lasting positive change for families and small businesses.

The Father's Table Foundation Grant aims to glorify God by addressing the immediate and future needs of women and children globally. This selective grant process emphasizes building self-sufficiency and resilience among beneficiaries, focusing on proven partners capable of expanding their impact. The foundation supports a diverse range of projects, including employment assistance, education, humanitarian aid, and health care, ensuring that aid not only meets urgent needs but also fosters long-term sustainability.

The Cudahy Fund offers general community grants focusing on social services, health, education, environment, and arts for under-resourced populations in Metropolitan Chicago and Wisconsin. Eligible applicants include 501(c)(3) nonprofit organizations. The fund aims to support initiatives that enhance community well-being, providing safety nets for marginalized groups and promoting access to quality education and cultural experiences. This fund does not support individual grants or projects outside its geographic focus.

The Caesars Foundation supports community-focused organizations through monetary and in-kind donations, prioritizing strategic areas like social equity, climate action, and mental health. Eligible applicants include IRS-recognized nonprofits and educational institutions operating within the U.S. Requests must align with these focus areas to enhance community impact. Organizations that discriminate or operate outside the U.S. are ineligible. By fostering collaboration, the foundation aims to uplift vulnerable populations and promote sustainable practices.

The IUSCCC Community-Academic Collaborative Program Award invites proposals aimed at addressing cancer burdens in Indiana through evidence-based programs. These initiatives must focus on major cancer types such as lung, breast, and prostate, and include an evaluation component. Community-led projects that engage underserved populations are particularly encouraged. The funding duration is one year, with a budget cap of $15,000. Proposals require prior approval through a Letter of Intent.

The Academic Research Enhancement Award (AREA) supports small-scale research grants for institutions with limited NIH funding, emphasizing biomedical research experiences for undergraduates. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over the past seven years. This initiative aims to enhance the research environment at these institutions, fostering student involvement in research activities.

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

The IN Conservation Stewardship Program (CSP) empowers agricultural producers to enhance their conservation efforts while improving their operations. Offering year-round applications, CSP provides technical and financial assistance for various goals, including improving grazing conditions and wildlife habitats. Key benefits include increased crop yields, reduced agricultural inputs, and enhanced resilience to environmental challenges. This program, managed by the USDA's Natural Resource Conservation Service of Indiana, supports sustainable farming practices that benefit both land and communities.

The Emerging Global Leader Award (K43) offers essential research support and protected time for early career scientists in low- and middle-income countries. This program, aligned with NIH's clinical trials policy, aims to cultivate independent research careers by providing mentorship and funding over three to five years. Eligible candidates must hold a junior faculty position at an accredited LMIC institution, fostering the growth of research capacity in their regions.

The Cleveland-Cliffs Foundation, established in 1962, focuses on enhancing educational opportunities, environmental protection, and community health in the regions it operates. As a leading steel manufacturer, Cleveland-Cliffs is committed to sustainability and responsible corporate citizenship. The foundation supports 501(c)(3) organizations that address key challenges in education, the environment, and community well-being, ensuring impactful investments that help communities thrive across North America.

The Huntington Impact Investment Philanthropy Grant Program aims to strengthen communities by supporting nonprofit organizations that enhance self-sufficiency and social equality. With a focus on areas such as community revitalization, affordable housing, and economic development, the program prioritizes initiatives that serve low- and moderate-income individuals. Organizations with IRS tax-exempt status can apply for funding to address critical community needs, fostering a more equitable environment for all.

The Fogarty Emerging Global Leader Award supports early career research scientists from low- or middle-income countries (LMIC) by providing research funding and mentored career development for three to five years. This program encourages LMIC scientists in health-related fields to develop projects aligned with their country's health priorities, fostering independent research careers within their institutions. Applications are welcomed from junior faculty members, enhancing global health research and capacity in LMICs.

About CommonSpirit

A calling that defines and unites

At CommonSpirit Health, we passionately care for the most vulnerable, relentlessly innovate how and where healing can happen and believe in uniting to benefit the common good. Our expansive network spans diverse communities, uniquely positioning us to meet their changing needs, improve population health and help chart the path to health equity.

Our mission, vision and values inform every aspect of our work each day and remind us that we serve our patients, their families, our communities – and each other. Our community health, research and home health programs help us address the primary barriers to healthier communities.

Sponsorship requests

We’re proud to support nonprofits that expand access to care, advance health equity and healthier communities. Learn more about our priorities.

Supporting our communities

CommonSpirit Health and our local facilities support nonprofit organizations that share our mission, vision and values. We give priority to programs that improve access to care and promote health equity and healthier communities.

CommonSpirit is proud to support nonprofit organizations that help improve the health and well-being of our communities. Guided by our mission, vision and values, we prioritize projects that focus on advancing health equity, improving access to care and improving community wellness.

The Joyce Foundation's Environment Grants focus on addressing critical environmental challenges in the Great Lakes region, such as climate change and water safety. The foundation prioritizes equitable, carbon-free energy solutions and clean water access for all communities. Grants are awarded to organizations committed to environmental justice and innovation in climate policy, particularly in Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin, ensuring that the voices of affected communities guide project development.

The John Ben Snow Memorial Trust Grant supports educational programs and initiatives that assist individuals demonstrating financial need. Founded in 1975, it prioritizes funding for organizations that enhance educational opportunities, arts, culture, and community initiatives, particularly for youth and disadvantaged populations. The Trust encourages proposals from 501(c)(3) organizations, with grants typically ranging from $10,000 to $20,000. It also considers limited proposals in disabilities, environmental protection, and historic preservation, focusing on educational impact.

Biogen Corporate Sponsorships provide funding to support congresses, events, and initiatives in exchange for tangible benefits such as marketing opportunities and recognition. Applications are reviewed on a rolling basis, and requests must be submitted 50 days in advance. Biogen considers various disease areas for sponsorship, including Alzheimer’s and Multiple Sclerosis. Approval depends on funding availability, alignment with interests, and event details, ensuring transparency for all potential sponsors.

About Regions

Regions Financial Corporation is a member of the S&P 500 Index and is one of the nation's largest full-service providers of consumer and commercial banking, wealth management and mortgage products and services. Regions serves customers across the South, Midwest and Texas.

Regions Foundation

Regions Foundation supports community investments that positively impact the communities served by Regions Bank. The Foundation engages in a grantmaking program focused on priorities including economic and community development; education and workforce readiness; and financial wellness. The Foundation is a nonprofit 501(c)(3) corporation funded primarily through contributions from Regions Bank.

Matching Gifts Program

Full-time associates and recent retirees (up to 5 years after retirement) of Regions and its affiliated companies can request a Regions Matching Gift to eligible organizations. The recipient organization must be a 501(c) or 170(c) organization located in the Regions footprint (except for accredited educational institutions, which may be located anywhere in the United States) and has a primary mission that clearly fits one of these categories:

• Economic and community development: Supporting economic prosperity through affordable housing, job creation, small-business development, homebuyer education and retention, neighborhood revitalization and stabilization, food security/hunger relief.
• Education and workforce readiness: Supporting career prosperity through student competency and skill building, college and career readiness, educational access and success, credential building and employment and educator training and resources.
• Financial wellness: Supporting financial prosperity through K-12 and college financial education, adult and workforce financial empowerment.
• Arts and culture: Organizations that promote visual or performing arts, historic or science museums, zoos, botanical gardens, libraries, parks or public radio and television.
• Service members and Veterans: Organizations that have a primary mission of supporting U.S. military service members and veterans.
• Individuals with disabilities: Organizations that have a primary mission of supporting individuals with disabilities.

Regions Matching Gifts for Recent Retirees

Retirees of Regions and its affiliated companies are eligible for the Matching Gift Program for up to 5 years after retirement (the gift date must be within the first 5 years of retirement). Regions will match donations of $25 or more, up to a total of $1,000 per year per retiree.

The Regions Community Affairs team will contact the organization on your behalf to verify the gift and review eligibility.

About Regions

Regions Financial Corporation is a member of the S&P 500 Index and is one of the nation's largest full-service providers of consumer and commercial banking, wealth management and mortgage products and services. Regions serves customers across the South, Midwest and Texas.

Regions Foundation

Regions Foundation supports community investments that positively impact the communities served by Regions Bank. The Foundation engages in a grantmaking program focused on priorities including economic and community development; education and workforce readiness; and financial wellness. The Foundation is a nonprofit 501(c)(3) corporation funded primarily through contributions from Regions Bank.

Matching Gifts Program

Full-time associates and recent retirees (up to 5 years after retirement) of Regions and its affiliated companies can request a Regions Matching Gift to eligible organizations. The recipient organization must be a 501(c) or 170(c) organization located in the Regions footprint (except for accredited educational institutions, which may be located anywhere in the United States) and has a primary mission that clearly fits one of these categories:

• Economic and community development: Supporting economic prosperity through affordable housing, job creation, small-business development, homebuyer education and retention, neighborhood revitalization and stabilization, food security/hunger relief.
• Education and workforce readiness: Supporting career prosperity through student competency and skill building, college and career readiness, educational access and success, credential building and employment and educator training and resources.
• Financial wellness: Supporting financial prosperity through K-12 and college financial education, adult and workforce financial empowerment.
• Arts and culture: Organizations that promote visual or performing arts, historic or science museums, zoos, botanical gardens, libraries, parks or public radio and television.
• Service members and Veterans: Organizations that have a primary mission of supporting U.S. military service members and veterans.
• Individuals with disabilities: Organizations that have a primary mission of supporting individuals with disabilities.

Regions Matching Gifts for Full-Time Associates

Regions supports organizations important to our associates through the Regions Matching Gifts Program. This program, which is open for use for all full-time Regions associates, affiliate associates and recent retirees, allows you to make an even greater difference to your favorite charities by doubling your tax-deductible contributions to these organizations. 

The Clif Family Foundation Open Call invites 501(c)(3) organizations to apply for grants supporting general operating costs or specific projects. With a focus on regenerative farming, food worker health, climate justice, and food access, the foundation aims to empower grassroots initiatives. Grants range from $5,000 to $50,000, with applications reviewed twice a year. Deadlines are March 1 and August 1, and announcements occur about four months post-deadline.

The CFGFW Agile Grants program, offered by the Community Foundation of Greater Fort Wayne, provides funding up to $20,000 for innovative projects that enhance the community's quality of life. Emphasizing diversity and inclusion, these grants support various issue areas, including education, health, and arts. Applications are accepted from March to October, and organizations can apply for new initiatives or significant enhancements to existing programs. This initiative aims to create lasting, positive impacts across Allen County and Northeast Indiana.