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Best Large Grants for Nonprofit Organizations in Indiana

Find the perfect Large Grants for Nonprofit Organizations in Indiana on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Indiana in the United States.

10,000+

Available grants

$2.62B

Total funding

$5K

Median grant

10,000+ grants
$2.62B total
$5K median

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9,901 Results based on applied filters

Youth Climate Justice Fund

Climate Group Inc.
Private
Africa, Americas +2 more
Up to US $40,000

About Us

The Youth Climate Justice Fund aims to support climate justice young leaders with trust-based funding, resources, and capacity strengthening, enabling them to amplify their voices and to keep their vision and influence alive.

Collectively, we have the power to ignite meaningful change and build equitable and sustainable futures. Despite the challenges posed by the current crisis, youth climate justice organizers remain determined to address current issues and explore new approaches.

Mission & Purpose

We work to strengthen existing organizing efforts and support emerging youth-led initiatives with a focus on bridging funders and organizers to enable flexible and impactful support. Through capacity strengthening and resource sharing, we empower and support young people to drive change and build a just and sustainable future.

How To Apply

The Youth Climate Justice Fund provides funding to emerging youth-led climate justice and socio-environmental groups through a participatory decision-making process.

Environmental Justice & Advocacy Climate Change Resilience & Equity Sustainability +3 more

AWWA Scholarship Program - GFT Forces of Change Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $5,000
The AWWA Scholarship Program offers the GFT Forces of Change Scholarship, providing $5,000 to undergraduate or graduate engineering students passionate about advancing the water industry. This scholarship underscores AWWA's commitment to nurturing future professionals who will tackle critical infrastructure challenges. By investing in education, AWWA aims to empower the next generation to innovate and lead in water supply solutions. This initiative highlights the importance of skilled engineers in shaping a sustainable future.
Sanitation & Clean Drinking Water Water Resource Management Engineering +2 more

Brower Youth Awards for Environmental Leadership

Earth Island Institute Inc
Private
North America
US $3,000
The Brower Youth Awards for Environmental Leadership honors young leaders aged 13 to 22 in North America who excel in environmental initiatives. Awardees receive a $3,000 cash prize, training, and networking opportunities to enhance their impact. This prestigious program fosters youth leadership and amplifies diverse voices within the environmental movement, encouraging innovative solutions to pressing ecological challenges. Over the past 25 years, the awards have celebrated over 100 emerging leaders dedicated to making a difference in their communities.
Environmental Justice & Advocacy Environmental Stewardship Youth Development & Leadership +3 more

Elizabeth Furber Scholarship

Native Forward Scholars Fund
Association/Society
United States
US $100 - US $30,000
The Elizabeth Furber Scholarship honors the legacy of Elizabeth Furber by providing financial assistance to American Indian and Alaska Native female graduate students. This scholarship supports students pursuing full-time degrees in various fields, including fine arts, music, and creative writing. As a need-based award, it requires applicants to demonstrate Tribal affiliation through a Tribal Eligibility Certificate. This opportunity empowers eligible students to achieve their academic goals.
Academic Scholarship Programs Writing & Literature Performing Arts +6 more

Hazen and Sawyer Scholarship

American Water Works Association (AWWA)
Association/Society
United States
US $10,000
The Hazen and Sawyer Scholarship, valued at $10,000, is awarded annually to a graduate-level candidate dedicated to addressing critical challenges in drinking water, water reuse, and water resources. Sponsored by the American Water Works Association (AWWA), this scholarship supports students who are permanent residents of the U.S., Mexico, or Canada. Eligible funds cover tuition, books, and related educational expenses, enhancing the recipient's ability to contribute to the water industry.
Environmental Contamination & Pollution Water Resource Management Environmental Policy

HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HIV Prevention and Alcohol R61/R33 funding opportunity aims to advance innovative HIV prevention strategies through a phased research approach. The R61 phase focuses on developing and pilot testing interventions, addressing key implementation questions for diverse populations. Following successful milestones, the R33 phase expands testing of these interventions and explores their effectiveness and sustainability, particularly in relation to alcohol use and related health issues.
Infectious & Parasitic Diseases HIV / AIDS Preventative Healthcare

Old National Bank Foundation Sponsorships

Old National Bank
Corporate
Allen County, Indiana, Berrien County, Michigan +58 more
Unspecified amount
The Old National Bank Foundation provides sponsorships to enhance community initiatives in Indiana, Illinois, Kentucky, Michigan, Minnesota, and Wisconsin. Their mission focuses on social responsibility, supporting underrepresented groups, and aligning with the Community Reinvestment Act. Sponsorships cover events such as fundraisers and sporting events, emphasizing active engagement and measurable impact. The Foundation aims to improve quality of life through strategic partnerships and meaningful contributions.
Financial Literacy Economic Services & Development Workforce Preparation & Job Readiness +2 more

NIHCM: Journalism Grants

The National Institute for Health Care Management
Private
United States
Unspecified amount
The NIHCM Journalism Grants support projects that enhance health reporting and education, targeting critical issues such as healthcare affordability, pharmaceutical pricing, provider market dynamics, and chronic disease management. This initiative emphasizes the importance of informing policymakers and the public on how to improve healthcare quality and access in the U.S. Proposals may also explore the role of artificial intelligence in healthcare delivery. Applications are welcome from journalists, nonprofits, and universities.
Journalism Health Information Technology Health Policy & Advocacy +5 more

Grants for Processors/Materials Recovery Facilities (MRF)

The Recycling Partnership
Private
United States
Unspecified amount

About Us

The Recycling Partnership is a team of experts, practitioners, and thought leaders who are deeply invested in protecting our natural resources, creating more sustainable communities, and delivering on our mission of building a better recycling system. We work alongside communities, companies, and policymakers to enact meaningful change across the entire recycling industry.

We firmly believe that if you want to recycle, you should be able to recycle. A robust and accessible recycling system is how we achieve this goal. A better system will deliver the true economic and environmental benefits that our people, our communities, and our entire recycling industry deserve.

This is our mission. This is our purpose. This is who we are. 

Grants for Processors/Materials Recovery Facilities (MRF)

Designed to help equipment manufacturers and MRFs boost throughput and increase capacity. 

Waste Management Recycling

15 and the Mahomies Foundation Grants

15 And The Mahomies Foundation
Private
United States
Up to US $15,000
The 15 and the Mahomies Foundation Grants aim to enhance the lives of children by supporting health, wellness, and community initiatives. This private foundation seeks to fund 501(c)(3) non-profit organizations, focusing on charitable causes. Grant requests are reviewed quarterly, and applicants must meet eligibility criteria. However, the foundation does not accept applications from individuals or for non-charitable items such as autographs or game tickets.
Children’s Health & Pediatrics Children’s Mental Health Children With Disabilities +4 more

Hamilton County Community Foundation Competitive Grants

Central Indiana Community Foundation
Private
Hamilton County, Indiana
Up to US $50,000
The Hamilton County Community Foundation offers competitive grants to nonprofit organizations aiming to strengthen community welfare. Priorities include childcare, housing, social services, and workforce education. Eligible applicants must be 501(c)(3) organizations with an EIN and can only lead one proposal at a time. Ineligible entities include individuals and organizations with discriminatory practices or those involved in political lobbying. All interested parties are encouraged to consult with community leadership before applying.
Education Basic Human Needs Workforce Preparation & Job Readiness +3 more

Lilly Endowment GIFT IX Community Project Grant

Community Foundation of Morgan County
Private
Morgan County, Indiana
Up to US $500,000

Community Foundation of Morgan County

The Community Foundation of Morgan County (CFMC) was founded on January 5, 2000, thanks to a grant from Lilly Endowment. CFMC was originally a partnership with the Mooresville Community Foundation and Morgan County Community Foundation. The historic Academy Building on the Newby Campus in Mooresville was CFMC’s original location.

After 25 years of service, the Community Foundation of Morgan County continues to grow our community endowment for purposes of enhancing the lives of all Morgan County citizens, now and for those in the future. We address community needs through grantmaking, including scholarships, connect donors to local needs, and provide leadership on key community issues.

Lilly Endowment GIFT IX Community Project Grant

The Community Foundation of Morgan County is committed to strengthening the long-term vitality of our community by addressing critical needs. The Community Project Grant Program, funded by Lilly Endowment Gift IX, provides strategic funding opportunities for transformative initiatives aligned with three key pillars:

  • Affordable Housing- Temporary & Permanent
  • Childcare Access & Affordability
  • Food Insecurity & Poverty Relief

Up to $500,000 in funding is available per pillar to support high-impact, collaborative, and sustainable solutions that directly benefit residents of Morgan County.

Poverty Alleviation & Services Food Security Child Welfare Services +2 more

Improving Health Decision Making With Comparative Clinical Effectiveness Research: Retrospective Observational Studies Leveraging Existing Data Sources PCORI Funding- Cycle 1 2026

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $2,000,000
This funding opportunity from the Patient-Centered Outcomes Research Institute aims to enhance health decision-making through comparative clinical effectiveness research, focusing on critical areas such as cancer, maternal health, and mental health. The initiative encourages robust observational studies that utilize existing data to derive patient-centered insights. Applications must address specific themes approved by PCORI and demonstrate potential benefits to the U.S. healthcare system, thus ensuring relevance and stakeholder engagement in research efforts.
Cancer / Oncology Maternal And Perinatal Health Endocrine & Metabolic Diseases +2 more

Medical and Graduate Student Preceptorship

Rheumatology Research Foundation
Private
United States
US $4,000
The Medical and Graduate Student Preceptorship provides a unique opportunity for students to engage in rheumatology through either clinical or research experiences lasting 4 to 8 weeks. Participants will observe practices in a shadowing role, gaining invaluable insights without direct patient management. The program supports students with financial awards of $2,000 or $4,000, depending on the duration of their preceptorship, and includes additional funds for travel expenses to attend professional conferences.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Rheumatology Scholarship – Undergraduate Students and Post-Baccalaureate Training

Rheumatology Research Foundation
Private
United States
US $2,000
The Rheumatology Scholarship supports undergraduate and post-baccalaureate students in attending ACR Convergence 2025, a premier event for rheumatology. Awardees gain exposure to innovative research and networking opportunities, enhancing their understanding of rheumatic diseases. The scholarship includes $2,000 for travel expenses and complimentary registration, encouraging future professionals to explore careers in this essential field. This initiative aims to strengthen the rheumatology workforce, ensuring better care for patients with musculoskeletal diseases.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Rheumatology Scholarship – Workforce Expansion

Rheumatology Research Foundation
Private
United States
US $2,000
The Rheumatology Scholarship – Workforce Expansion aims to recruit future rheumatology professionals by supporting students and residents from underserved areas to attend ACR Convergence 2025. Awardees receive $2,000 for travel, registration, and a one-year ACR/ARP Membership. This initiative fosters networking opportunities and educational experiences crucial for enhancing patient care in rheumatology. It is part of a broader campaign to address the growing shortage of rheumatologists and improve patient access to care.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Student & Resident Research Award

Rheumatology Research Foundation
Private
United States
US $2,000
The Student & Resident Research Award, part of the Choose Rheumatology campaign, recognizes outstanding students and residents for significant contributions in rheumatology. Eligible applicants must be authors of abstracts submitted to ACR Convergence 2025 and can receive up to $2,000 in funding for travel and registration. This award promotes engagement in rheumatology through innovative learning experiences at ACR Convergence, enhancing the understanding and care for patients with rheumatic diseases.
Musculoskeletal Diseases Immune System Diseases Arthritis +1 more

Centers for Structural Biology of HIV and other Infectious Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount

The Centers for Structural Biology of HIV and Other Infectious Diseases aims to support innovative frontier science research that establishes new technologies and methodologies to provide insight into the mechanisms of hostpathogen interactions, as well as translational research to inform the development of novel and/or improved preventive interventions, therapeutics, diagnostics, and curative interventions across a broad spectrum of infectious diseases. These Centers focus on understanding the dynamics of molecular complexes, with the intention of informing mechanistically based discovery and/or design of interventions for the prevention, treatment, and cure of HIV and other infectious diseases. The goal is to facilitate the discovery of new therapeutic targets, new classes of interventions ranging from diagnostics, to small molecules and protein therapeutics, to neutralizing antibodies, and novel vaccine candidates, including nanoparticle vaccines, elucidate the mechanisms of action of interventions, and to determine the structural basis for interventional failures, but not support end-to-end preclinical development.

Of particular interest are the components of infectious agents and/or hosts for which sufficiently complete structureshave yet to be determined, including macromolecular complexes of proteins, nucleic acids, carbohydrates, lipid membranes, and/or small molecules. The Centers will be responsible for the validation of structural data using biological, biochemical, and computational methods and artificial intelligence (AI) models to help understand the biological mechanisms and structure-function relationships of these complexes.

Sexually Transmitted Diseases HIV / AIDS

Wildlife Annual Grants - Established Investigator ( Avian/Fish/Invertebrates)

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Approximately US $100,000
Morris Animal Foundation invites Established Investigators to submit pre-proposals for research focused on reptile and amphibian health. This initiative emphasizes the importance of animal health and welfare while facilitating impactful conservation efforts. Proposals must demonstrate clear animal health needs, collaborative strategies, and potential benefits to wildlife populations. Funding for these projects is anticipated to average around $100,000 over a maximum duration of 36 months, fostering innovative solutions for pressing health challenges in these species.
Herpetology Wildlife Health

Wildlife Health (Reptile and Amphibian) - First Award

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Up to US $120,000
The Morris Animal Foundation invites research pre-proposals for the Wildlife Health (Reptile and Amphibian) - First Award, aimed at enhancing the health and welfare of amphibians and reptiles. This initiative focuses on impactful research, particularly in chytrid disease. Eligible applicants include early career researchers with appropriate qualifications and a clear understanding of animal health challenges. Projects should demonstrate collaboration with relevant stakeholders and provide direct benefits to wildlife populations, emphasizing conservation through an animal health perspective.
Herpetology Wildlife Health

Wildlife Health (Reptile and Amphibian) - Pilot Study Awards

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Up to US $20,000
The Morris Animal Foundation is offering Pilot Study Awards focused on reptile and amphibian health and welfare, particularly for chytrid research. These awards aim to fund innovative, proof-of-concept studies that demonstrate a clear understanding of animal health issues and collaboration with stakeholders. Proposals must have a direct impact on wildlife populations and adhere to strict health study policies. The maximum funding is $20,000 for a duration of 12 months, ensuring significant contributions to wildlife health advancements.
Herpetology Wildlife Health

Highland Orchestra Scholarship

Legacy Foundation: Lake County's Community Foundation
Private
United States
US $500

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Highland Orchestra Scholarship

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

Symphony / Orchestra Education - Higher Education Education - High School +1 more

Jeanette Zaichkin NRP Nursing Grant for Excellence and Innovation in NRP Education

American Academy Of Pediatrics
Private
Canada, United States
Up to US $10,000
The Jeanette Zaichkin NRP Nursing Grant for Excellence and Innovation in NRP Education supports nurses dedicated to enhancing neonatal resuscitation training. This grant, offered by the American Academy of Pediatrics, provides up to $10,000 for innovative projects addressing key gaps in transitional physiology and evidence-based practices. Eligible applicants must be current NRP Instructors and work in neonatal care settings. The initiative aims to empower nurses in teaching essential skills for successful newborn resuscitation.
Nursing Obstetrics & Neonatal Care Medical Education & Professional Training +1 more

Grants for Community Recycling Programs

The Recycling Partnership
Private
United States
Unspecified amount
The Recycling Partnership offers grants for community recycling programs, providing nearly $50 million to support 370 communities since 2014. Their mission is to create a robust and accessible recycling system that benefits people and the environment. Eligible applicants include publicly, privately, and non-profit owned MRFs in the U.S. This initiative aims to enhance curbside, drop-off, and multifamily recycling, ensuring that everyone can participate in sustainable practices.
Waste Management Recycling

AAAAI Allied Health Recognition Award

American Academy of Allergy, Asthma & Immunology (AAAAI)
Association/Society
United States
Unspecified amount
The AAAAI Allied Health Recognition Award honors non-physician members who have significantly contributed to allergy and immunology education or research. As part of the American Academy of Allergy, Asthma & Immunology, this award emphasizes the importance of allied health professionals in advancing patient care. Eligible recipients include AAAAI Allied Health members who demonstrate excellence in their field, ensuring that contributions to the specialty are recognized and celebrated.
Immune System Diseases Asthma Allergies & Allergic Diseases +1 more

Wisdom Family Foundation Grant Program

Wisdom Family Foundation
Private
Anoka County, Minnesota, Ashland County, Wisconsin +34 more
US $1,000 - US $5,000
The Wisdom Family Foundation Grant Program supports organizations that empower children and strengthen communities. Founded in 2007, this 501(c)(3) nonprofit focuses on providing essential resources such as food security and educational assistance. Grants typically range from $1,000 to $5,000, with larger capital grants considered on a case-by-case basis. The Foundation operates primarily in Greater Chicago, Northern Wisconsin, and the Twin Cities, promoting a spirit of generosity and collaboration within communities.
Child Care Services Children’s Health & Pediatrics Children’s Mental Health +4 more

Large Grants for Nonprofit Organizations in Indiana Highlights

Looking for large grants for nonprofit organizations in Indiana?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Indiana recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in Indiana

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in Indiana grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

49 Large Grants for Nonprofit Organizations in Indiana over $25K in average grant size

37 Large Grants for Nonprofit Organizations in Indiana over $50K in average grant size

33 Large Grants for Nonprofit Organizations in Indiana supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in Indiana supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Indiana?

Most grants are due in the second quarter.

Q1
24.6%
Q2
28.1%
Q3
23.6%
Q4
23.7%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Indiana?

Grants are most commonly $14,375.

$375 $375 Min.
$14,375 $14.4 K Median
$429,344 $429.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Indiana?

Grants are most commonly $158,271.

$158,271

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Indiana year over year?

In 2024, funders in Indiana awarded a total of 42,920 grants.

2022 40,294

2023 39,261

2024 42,920

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Indiana given out in Indiana, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Indiana changing over time?

Funding has increased by 35.58%.

2022 $4,633,293,808

2023 $4,997,384,462
7.86%

2024 $6,775,520,204
35.58%

Indiana Counties That Receive the Most Funding

How does grant funding vary by county?

Marion County, Monroe County, and Tippecanoe County receive the most funding.

County Total Grant Funding in 2024
Marion County $5,951,081,269
Monroe County $587,464,361
Tippecanoe County $370,158,455
St Joseph County $332,109,828
Allen County $235,684,076