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Best Large Grants for Nonprofit Organizations in Indiana

Find the perfect Large Grants for Nonprofit Organizations in Indiana on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Indiana in the United States.

10,000+

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$2.62B

Total funding

$5K

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10,000+ grants
$2.62B total
$5K median

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Education & Advanced Manufacturing/Logistics, Apprenticeship Grant Opportunity

Indiana Department of Workforce Development
State/Local Government
Indiana
Up to US $400,000

Indiana DWD – Who We Are

The Indiana Department of Workforce Development (DWD) strengthens Indiana by understanding workforce needs, aligning resources, and providing access to services that empower Hoosiers to thrive in an ever-changing economy. By helping to ensure economic security and better employment outcomes for all Indiana residents, the state government agency prides itself on acting with integrity, accountability, and respectfulness while continuously striving to support employers, as well as guide and upskill job seekers.

Education & Advanced Manufacturing/Logistics Apprenticeship Grant Opportunity (Round 1)

The purpose of this RFA is to solicit applications from qualified non-profit organizations to facilitate the expansion of Registered Apprenticeship Programs (RAPs) and Certified Pre-Apprenticeship in both number of available programs and individual participants in the occupations of Education as well as Advanced Manufacturing and Logistics. The outcome of this expansion will focus on the number of programs created, number of participants assisted, as well as the development of communities of practice through award recipients. 

Funds not distributed in the first round will be available in subsequent rounds of grant opportunities.

Workforce Preparation & Job Readiness Vocational & Trade Education Apprenticeship & Internship Programs +2 more

Hearst Foundation: Social Service Grant

William Randolph Hearst Foundation
Private
United States
More than US $100,000
The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.
Sustainability Food Access & Hunger Family Services +10 more

Vulcan Materials Company Foundation Grant

Vulcan Materials Company Foundation
Corporate
Alabama, Arizona +21 more
Unspecified amount
The Vulcan Materials Company Foundation Grant focuses on enhancing community quality of life through education, environmental stewardship, and employee involvement. Established in 1988, the Foundation supports public charities and government units, prioritizing proposals that improve public education and promote sustainable practices. Special consideration is given to initiatives that engage Vulcan employees and integrate multiple focus areas, ensuring a positive impact in the local communities where Vulcan operates.
Education - Higher Education Education - K through 12 Environmental Stewardship +2 more

Employer Training Grant - Early Childhood Education

Indiana Department of Workforce Development
State/Local Government
Indiana
Up to US $50,000
The Employer Training Grant for Early Childhood Education, offered by the Indiana Department of Workforce Development, supports Hoosier employers in training and retaining staff in high-demand sectors. With reimbursements up to $50,000, the grant focuses on job skills training that aligns with eligible occupations and requires at least 40 hours of training. Employers must ensure new hires earn a minimum wage of $19 per hour and existing employees receive a 5% wage increase post-training.
Workforce Preparation & Job Readiness Education - Preschool / Early Learning Child Care Services

Mildred B. Price Nursing Scholarship

Hamilton County Community Foundation Inc
Private
Indiana
Unspecified amount
The Mildred B. Price Nursing Scholarship, established by William B. Price in honor of his mother, supports aspiring nursing students in Indiana. This scholarship aims to empower residents of Grant, Hamilton, Knox, Madison, Pulaski, Starke, or White Counties. Eligible applicants must demonstrate financial need and maintain a GPA of 2.5 or higher while pursuing a nursing degree at any Indiana college or university. This initiative fosters equitable opportunities in the nursing profession.
Education - Higher Education Academic Success & Enrichment Education - High School +2 more

Arbor Rising Grant

Arbor Brothers Inc
Private
Alabama, Arizona +43 more
US $125,000 - US $175,000
Arbor Rising Grant, established in 2010, is a NYC-based nonprofit providing unrestricted multi-year funding and capacity-building support to nonprofits focused on alleviating poverty. The grant process occurs every three years, with the next round in 2025 being invitation-only. Eligible organizations must demonstrate high potential and effective leadership, typically operating on a modest budget. Arbor Rising prioritizes applicants from the NYC metro area while expanding to cover the lower 48 US states.
Poverty Alleviation & Services Nonprofit Growth & Development Workforce Preparation & Job Readiness +1 more

Big Bets Fellowship: US

Rockefeller Foundation
Private
United States
US $5,000
The Big Bets Fellowship: Economic Opportunity in the United States is a transformative 4-month program designed to empower emerging leaders to tackle economic challenges head-on. With a focus on innovative solutions for job creation, affordable housing, and equitable access to resources, the fellowship equips participants with essential skills and a supportive network. The initiative aims to drive systemic change and promote sustainable economic prosperity, addressing inequalities while fostering resilient communities across the nation.
Basic Human Needs Food Access & Hunger Economic Services & Development +12 more

Therapeutic Giving: Immunology

Johnson & Johnson Innovative Medicine
Corporate
United States
Unspecified amount
The Therapeutic Giving program by Johnson & Johnson focuses on funding initiatives that enhance patient access to treatment and advance health equity, particularly in immunology. Eligible nonprofit organizations can apply for support aimed at improving health outcomes through innovative programs. The initiative prioritizes measurable impacts over fundraising activities, emphasizing the importance of addressing healthcare disparities and promoting disease awareness efforts for diseases like rheumatoid arthritis and psoriasis.
Immune System Diseases Crohn’s Disease And Colitis Skin Diseases & Dermatology +6 more

Major Richard L. Ridder Memorial Scholarship

Central Indiana Community Foundation
Private
Indiana
Unspecified amount
The Major Richard L. Ridder Memorial Scholarship, established by Mary Ann Ridder, honors her husband’s dedication to the Indiana National Guard and the value of education. Open to Indiana residents, it supports current or former members of the National Guard and their families. Applicants must show financial need and maintain a GPA of 2.0 or higher. Scholarships can be used for tuition, fees, and educational expenses at accredited institutions in Indiana.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Large Creative & Performing Arts Grants

University Of Notre Dame Du Lac
Private
Indiana
Up to US $25,000
The Large Creative & Performing Arts Grants, offered by the University of Notre Dame's Franco Family Institute, support innovative arts projects led by faculty in the College of Arts & Letters. These grants are awarded biannually and prioritize projects that foster social engagement, explore sacred themes, or integrate technology with the arts. Eligible faculty can use the grants for materials, travel, and exhibition costs, enhancing the creative landscape and encouraging collaboration among scholars and artists.
Performing Arts Visual Arts Architecture +3 more

CIF ; Impact awards

Endeavor Health
Private
United States
US $1,000,000

About

Being deeply connected to the community means more than providing access to excellent healthcare. It means understanding, and investing in, the health needs of our community.

Through our Community Investment Fund (CIF), Endeavor Health has awarded more than $38.5 million to 59 local partnerships dedicated to enhancing community health and wellbeing, advancing health equity and supporting local economic growth. Together, we’re committed to helping everyone in our communities be their best.

Award categories

Through the CIF, we will make meaningful and intentional investments through impact awards and capacity builder awards. These awards are intended to meaningfully advance the health of our community over time towards three bold aspirations through investments in five areas of focus.

We aspire to a future where:

  • A person’s zip code does not determine how long they will live
  • Hunger and homelessness in our communities are history
  • The healthcare workforce is thriving and representative of the communities we serve

To help advance these aspirations, the CIF will invest in the following areas:

  • Access to healthcare
  • Behavioral health
  • Food insecurity
  • Housing insecurity
  • Workforce development for careers in healthcare

Impact awards

  • Designed for 5-year initiatives where organizations come together to drive measurable impact and longer-term change in the communities we serve by improving existing systems and innovation
  • Emphasize strategic cross-sector and/or intra-sector partnerships between community-based organizations
  • Uplift community members of greatest need
  • Directly align with CIF areas of focus and meaningfully contribute to CIF goals
  • Award amount: $1 million per year, up to 5 years
Workforce Preparation & Job Readiness Food Security Health Care Access & Delivery +5 more

CIF : Capacity builder awards

Endeavor Health
Private
United States
US $100,000 - US $500,000
The CIF Capacity Builder Awards by Endeavor Health focus on enhancing community health through strategic investments. With over $38.5 million allocated to local partnerships, these awards aim to address critical areas like healthcare access, food insecurity, and workforce development. Designed for nonprofit organizations, the awards range from $100,000 to $500,000 annually for 1-2 years, fostering long-term community impact and advancing health equity in the service areas.
Homelessness Services Workforce Preparation & Job Readiness Food Security +5 more

NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Clinical Trial Required) (355399)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NHLBI Career Transition Award (K22) program supports postdoctoral fellows in transitioning their research to extramural institutions. The program includes a mentored intramural phase (up to two years) followed by an extramural phase (three years), totaling five years of support. Applications have multiple deadlines, including October 12, 2024, and February 12, 2025, among others. Successful transition depends on the awardee's progress during the mentored phase, evaluated by NHLBI.
Cardiovascular Diseases & Systems Hematological Systems Respiratory Diseases & Systems +10 more

Corporate Giving Program: Requests under $1000

Franklin P. and Arthur W. Perdue Foundation
Private
California, Canada +19 more
Up to US $1,000
The Corporate Giving Program by the Franklin P. and Arthur W. Perdue Foundation focuses on supporting nonprofit organizations within specific states. They prioritize initiatives that enhance community welfare, especially in agriculture, education, health, and environmental sustainability. Organizations must have 501(c)(3) status to apply, and preference is given to those involving Perdue associates. Ineligible requests include those from religious, political, or individual-focused groups. This program emphasizes broad community benefits over organizational affiliations.
Education Agriculture Poverty Alleviation & Services +5 more

Pinetop Assistance League (PAL) Grant

Pinetop Perkins Foundation
Association/Society
United States
US $500
The Pinetop Assistance League (PAL) Grant provides crucial financial support to elderly blues musicians, ensuring their well-being during emergencies. This grant, part of the Pinetop Perkins Foundation's mission, offers assistance for medical expenses, home care, and essential living costs. Eligible applicants must be professional artists aged 50 or older with a household income below $35,000. By addressing these needs, PAL plays a vital role in preserving the legacy and care of blues musicians.
Music Crisis Intervention Emergency Medical Care & Services +6 more

JBF Do Good Grant

Joe Burrow Foundation
Private
East Baton Rouge Parish, Louisiana, Indiana +3 more
Up to US $10,000
The JBF Do Good Grant, established by the Joe Burrow Foundation, aims to support innovative projects that assist underprivileged children, particularly those facing mental health challenges and food insecurity. Eligible organizations include nonprofits and public charities, with proposals up to $10,000 considered. The foundation encourages creative solutions that foster lasting impacts within communities in Greater Cincinnati and Baton Rouge. By fostering these initiatives, the foundation continues Joe Burrow's commitment to community service and social responsibility.
Children’s Mental Health Food Access & Hunger Poverty Alleviation & Services

Carol & Hugh Warnecke Teacher Scholarship

Central Indiana Community Foundation
Private
Indiana
Unspecified amount
The Carol & Hugh Warnecke Teacher Scholarship, provided by the Central Indiana Community Foundation, supports Indiana residents pursuing a degree in secondary education. This scholarship aims to assist individuals with academic promise and financial need, particularly those making a career change into teaching. Eligible expenses include tuition, fees, and, in some cases, room and board. Applications are encouraged from those attending any accredited Indiana college or university.
Education - Higher Education Academic Scholarship Programs College Success / Persistence +2 more

Nina Mason Pulliam Charitable Trust Grants (Environmental Requests)

Nina Mason Pulliam Charitable Trust
Private
Arizona, Indiana
Unspecified amount
The Nina Mason Pulliam Charitable Trust focuses on supporting nonprofit organizations in Arizona and Indiana through grants aimed at environmental initiatives. With a commitment of $19.5 million over five years, the Trust emphasizes the protection and restoration of critical waterways, particularly the Verde and White rivers. Eligible organizations must be 501(c)(3) public charities, and the Trust prioritizes projects that promote environmental awareness and stewardship, improving community engagement with nature.
Environmental Conservation Environmental Education Environmental Stewardship +1 more

J.W. Couch Foundation: Storytelling Grant

Jesse W Couch Charitable Foundation
Private
United States
More than US $50,000
The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.
Historic Preservation Environmental Conservation Renewable/Sustainable Energy +10 more

APN 2025 Call for Proposals: CRRP

Mountain Research Initiative
Association/Society
Australia, Bangladesh +23 more
Unspecified amount

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CRRP 

Through the competitive Collaborative Regional Research Programme (CRRP), we promote regional research that has potential to improve our understanding of global change and its implications while contributing to a sound scientific basis for policymaking in areas affected by global change. Under this pillar, APN supports collaborative research that contributes to the evolving science-policy arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction and the UN Decade of Ocean Science as well as ongoing and new global change and sustainability research programmes.

Activities of interest under the CRRP Programme

APN promotes regional collaborative research that improves understanding of the physical, biological and human dimensions of change in the Earth system and advances actionable science that informs decision-making. APN accepts proposals that engage at least 3 member/approved countries in the region, and prioritise collaboratively designed, actionable research with non-academic stakeholders. Proposals must address one or more of the following activities:

  • Collaborative research on global change and sustainability that particularly addresses GAPS, ANALYSIS, SYNTHESIS and ASSESSMENT work.
  • Collaborative research that develops PATHWAYS and MECHANISMS to achieve sustainable development, and develop adaptation strategies.
  • Collaborative PLACE-BASED INTEGRATIVE RESEARCH, particularly from developing countries.
  • Collaborative research that is CO-DESIGNED to contribute to the Paris Agreeemnt, Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, Post-2020 Global Biodiversity Framework, UN Decade of Ocean Science (2021-2030), and the accumulation of scientific knowledge at IPCC, IPBES, etc.
Environmental Contamination & Pollution Environmental Health Air Quality +4 more

MDFF Educational Scholarship

Muscular Dystrophy Family Foundation (MDFF)
Association/Society
Indiana
US $2,000
The MDFF Educational Scholarship, sponsored by Busey Bank, supports Indiana residents diagnosed with muscular dystrophy or neuromuscular diseases in achieving their educational goals. Established in memory of Andrew "Sparky" Seever, this $2,000 scholarship emphasizes financial need, academic achievement, leadership, community involvement, and character. The Muscular Dystrophy Family Foundation has been assisting individuals since 1958, ensuring that education remains accessible for all.
Academic Scholarship Programs Neurological Diseases & Disorders Muscular Dystrophy

Mental Wellness Grants

Community Foundation of White County (CFWC)
Association/Society
Indiana
Up to US $75,000

About Us

Community Foundation of White County

Your community foundation is a philanthropic, nonprofit 501c3 organization that partners with visionary donors who believe that philanthropy has power to positively transform our White County community … forever.

To strengthen and transform our White County community by fostering charitable giving, philanthropic aspirations, and leadership.

Grants Available

Mental Wellness Grants

Through this grant cycle, $75,000 is available to non-profit organizations serving White County with a focus on mental wellness initiatives. Awards to be announced 10/30/26.

Mental Health & Psychiatric Diseases Youth Services Health Care Access & Delivery +2 more

Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required) (357288)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health (NIH) is inviting applications for the Screening, Brief Intervention, and Referral to Treatment or Prevention (SBIRT/P) program. This funding opportunity aims to explore innovative methods for addressing alcohol, tobacco, and other drug use among adults facing health disparities. The initiative seeks research proposals that will implement and evaluate SBIRT/P strategies in collaboration with healthcare and community partners. This approach is crucial for enhancing public health and ensuring effective interventions.
Preventative Healthcare Health Disparities & Social Determinants of Health Addiction & Substance Use Disorders +3 more

Heart of Cook Grants

Berrien Community Foundation
Private
Berrien County, Michigan, Cass County, Michigan +6 more
US $100 - US $10,000
The Heart of Cook Grants support non-profit organizations, schools, and government units in furthering education, enhancing human services, and protecting the environment within Southwest Michigan and Northwest Indiana. With funding priorities focused on skill development, community independence, and environmental restoration, the grants aim to foster local leadership and innovative solutions. Eligible applicants may submit one application per cycle, with particular attention given to measurable outcomes and projects addressing emerging community needs.
Workforce Preparation & Job Readiness Youth Services Environmental Conservation +11 more

Quik Trip Charitable Grants

Quik Trip
Corporate
Alabama, Arizona +21 more
Unspecified amount

About QuikTripQuikTrip believes in investing in the communities in which our employees live and work. Every year, QuikTrip donates 5% of our annual net profit to qualified 501c3 non-profit agencies, which includes our United Way campaign match, support for National Safe Place agencies, Folds of Honor scholarships and many other agencies that support at-risk youth and early childhood education.Mission: To wisely invest dollars in community efforts that will help impact (in measurable terms) individuals in our society who are dependent on the charitable support of others. We believe the most effective way to do that is to invest our contribution dollars and volunteers in strategic efforts that help those at risk reach their functional capacity as successful, independent citizens.About QuikTrip Charitable GrantsQuikTrip funds 501c3 agencies located in the cities in which we have stores and our employees live and work. Funding can include: “in-kind” products (coupons, gift cards or product donation), formal grants, fundraiser/event sponsorships and employee volunteer time.Focus Areas:

  • Creating Safe Communities
    • First Responders: QuikTrip is proud to partner with law enforcement and first responders in every market we serve, making sure that they have the tools, training and support they need to keep our communities safe and to return home safely to their families after each shift.
    • Homeless Outreach & Alternatives to Police Response: To significantly reduce non-emergency calls and help people in crisis get back on their feet, QuikTrip funds dedicated homeless outreach teams across our communities. These teams engage individuals experiencing homelessness and living in encampments – connecting people to services, shelter, detox and long-term care.

    • Creating Strong Communities
      • Ending Homelessness: We support emergency, transitional and permanent supportive housing, diversion and prevention programs, and more.
      • Mental Health & Substance Abuse : We know that healthy communities are safe communities, which is why we invest in detox and substance abuse treatment centers, and behavioral health centers and services to end the perpetuation of cycles of trauma and addiction.
      • At-Risk Youth: We especially prioritize services for at-risk youth – those aging out of foster care, justice-involved or without stable support systems.
    • Additional Community Commitments
      • United Way: Employee donation matching in all markets.
      • Folds of Honor: Scholarships for families of fallen or wounded service members and first responders.
      • National Safe Place: QT stores serve as Safe Place locations for youth in crisis, with trained staff ready to assist.
    Homelessness Services Mental Health & Psychiatric Diseases Youth Services +2 more

    Margaret Martin Roth Endowed Scholarship

    Hamilton County Community Foundation Inc
    Private
    Indiana
    Unspecified amount
    The Margaret Martin Roth Endowed Scholarship, established by the Hamilton County Community Foundation, offers financial support to Indiana residents enrolled in nursing programs. This scholarship aims to empower students who are sophomores or above in their pursuit of post-baccalaureate degrees. Preference is given to those with a GPA of 3.5 or higher and demonstrated financial need, ensuring that dedicated individuals have the opportunity to succeed in their educational endeavors.
    Education - Higher Education Academic Success & Enrichment Education - High School +2 more

    Wabtec Direct Grant Program

    Wabtec Foundation
    Corporate
    Ada County, Idaho, Alamance County, North Carolina +70 more
    US $1,000 - US $10,000
    The Wabtec Direct Grant Program focuses on creating sustainable impacts in local communities by funding 501(c)(3) non-profit organizations. Emphasizing education and environmental stewardship, the program supports initiatives that improve literacy, academic outcomes, and workforce readiness. Grants range from $1,000 to $10,000, prioritizing organizations that engage local Wabtec employees in volunteerism. The program promotes equitable access and non-discrimination while ensuring measurable results in funded projects.
    All fields of work Literacy Academic Success & Enrichment +10 more

    Large Grants for Nonprofit Organizations in Indiana Highlights

    Looking for large grants for nonprofit organizations in Indiana?


    Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Indiana recommended for your specific programs.

    Last updated: October 5, 2026. Next update: November 1, 2026.

    Grant Insights : Large Grants for Nonprofit Organizations in Indiana

    Grant Availability

    How common are grants in this category?

    Common — grants in this category appear regularly across funding sources.

    200+ Large Grants for Nonprofit Organizations in Indiana grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

    49 Large Grants for Nonprofit Organizations in Indiana over $25K in average grant size

    37 Large Grants for Nonprofit Organizations in Indiana over $50K in average grant size

    33 Large Grants for Nonprofit Organizations in Indiana supporting general operating expenses

    200+ Large Grants for Nonprofit Organizations in Indiana supporting programs / projects

    600+ Grants on Instrumentl focused on Food Access & Hunger

    400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

    Grant Deadline Distribution

    Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Indiana?

    Most grants are due in the second quarter.

    Q1
    24.6%
    Q2
    28.1%
    Q3
    23.6%
    Q4
    23.7%

    Typical Funding Amounts

    What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Indiana?

    Grants are most commonly $14,375.

    $375 $375 Min.
    $14,375 $14.4 K Median
    $429,344 $429.3 K Average
    $40,331,313 $40.3 M Max.

    Average Grant Size

    What's the typical amount funded for Indiana?

    Grants are most commonly $158,271.

    $158,271

    Total Number of Grants

    What's the total number of grants in Large Grants for Nonprofit Organizations in Indiana year over year?

    In 2024, funders in Indiana awarded a total of 42,920 grants.

    2022 40,294

    2023 39,261

    2024 42,920

    Top Grant Focus Areas

    Among all the Large Grants for Nonprofit Organizations in Indiana given out in Indiana, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

    1. Education

    2. Philanthropy, Voluntarism & Grantmaking Foundations

    3. Human Services

    Funding Over Time

    How is funding for Large Grants for Nonprofit Organizations in Indiana changing over time?

    Funding has increased by 35.58%.

    2022 $4,633,293,808

    2023 $4,997,384,462
    7.86%

    2024 $6,775,520,204
    35.58%

    Indiana Counties That Receive the Most Funding

    How does grant funding vary by county?

    Marion County, Monroe County, and Tippecanoe County receive the most funding.

    County Total Grant Funding in 2024
    Marion County $5,951,081,269
    Monroe County $587,464,361
    Tippecanoe County $370,158,455
    St Joseph County $332,109,828
    Allen County $235,684,076