Best Large Grants for Nonprofit Organizations in Indiana

The Benjamin H. Smyser Foundation, established by Fort Wayne resident Benjamin H. Smyser, focuses on supporting various charitable causes primarily within the Fort Wayne area. The foundation, operational since 1968, emphasizes arts, education, environmental efforts, health, human services, and religious initiatives. Organizations must be 501(c)(3) compliant to qualify for funding, with a preference for local beneficiaries. While there are no strict geographic limitations, preference is given to those serving Indiana residents.

The Health Information Outreach Award, funded by the National Library of Medicine, aims to enhance access to essential health information for underrepresented populations and healthcare professionals. This initiative focuses on improving health literacy and equity through diverse projects, including training, technology access, and community outreach. Eligible organizations from select Midwestern states can apply, prioritizing innovative solutions that address health disparities and promote informed health decisions among vulnerable communities.

The James M. Cox Foundation Grant offers support to nonprofit organizations focused on conservation, early childhood education, family empowerment, and health. Organizations must be 501(c)(3) tax-exempt and located in areas where Cox Enterprises operates. Grant applications are accepted year-round, with deadlines before Trustee meetings. Preference is given to organizations with a history of local engagement. This foundation embodies the philanthropic spirit of its founder, James M. Cox, by giving back to the community.

The XENO PRIZE for Performance Arts, awarded by Franklin Furnace, supports early-career LGBTQ+-identifying performance artists creating new work in 26 states with restrictive gender-affirming laws. This annual prize, established in 2023, offers $5000 to a selected recipient from proposals submitted for the Franklin Furnace FUND for Performance Art. The deadline for submissions is April 1, 2025, encouraging innovative voices in the contemporary performance art landscape.

The Eric A. Baade and Mary C. Baade Charitable Purposes Trust, established in 1958, aims to support diverse charitable causes primarily in Allen County, Indiana. The trust encourages organizations that qualify under Section 501(c)(3) of the Internal Revenue Code, focusing on areas such as arts, education, health, and human services. While there are no strict geographic limitations, local initiatives are prioritized to enhance community impact.

SC Johnson Grants aim to enhance community welfare through charitable contributions, focusing on health, sustainability, and opportunity. Since 1937, the company has committed five percent of its pretax profits to support registered charities and nonprofit organizations, especially in areas where it operates. The grant program prioritizes initiatives addressing healthcare access, environmental conservation, and educational equity, ensuring that efforts align with the values of community service and corporate responsibility.

The Conservation Connect Fellowship Program, offered by the National Forest Foundation, invites graduate students to engage in hands-on conservation projects. This fellowship provides practical experience, mentorship from conservation professionals, and training in collaborative leadership. Fellows will gain a deep understanding of forest management and expand their professional networks. With a focus on developing future conservation leaders, the program seeks students passionate about public lands and community engagement.

About Us

Our Mission

We create lasting impact through asset development, nonprofit capacity building, and community leadership. 

Our Vision

To enrich the lives of Wabash County residents by fostering opportunity, inspiring generosity, and building a thriving connected community. 

Our Scholarships

For High School Seniors & Non Traditional Students who are beginning college more than one year after high school.

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.    

Terry D. and Carol A. Agness Memorial Scholarship Endowment

Terry and Carol Agness’ children created this scholarship to honor their parents who believed in supporting local community projects like Meals on Wheels, the Honeywell Center, education, and students. The scholarship is awarded to a Purdue student pursuing a degree in engineering or business and is based on academic performance, school activities, church involvement, work experience, and financial need.

The Republic Bank Grants program supports non-profit organizations in Kentucky, Indiana, Ohio, Tennessee, and Florida that enhance community welfare through various initiatives such as education, healthcare, and civic projects. By providing financial and in-kind donations, Republic Bank aims to strengthen community ties and foster impactful change. Eligible organizations must have IRS 501(c) status and submit grant requests in writing at least two months in advance, ensuring timely support for their initiatives.

The Formative (Interim) Assessment Grant by the Indiana Department of Education supports schools in utilizing formative assessments to enhance curriculum and instruction. This funding is aimed at public school corporations, charter schools, and accredited non-public schools serving students from kindergarten to grade 10. By focusing on data-driven practices, this grant aims to improve educational outcomes and ensure targeted support for individual student needs.

Trauma System Development Grant

Purpose

The Indiana Department of Health’s Division of Trauma and Injury Prevention has been provided funding to support quality improvement projects and the ongoing development of the statewide trauma system. To aid in the implementation of trauma system projects, the Indiana Department of Health will fund the following strategies. Applicants must implement projects that target at least one strategy but can address multiple strategies if appropriate.

• Strategy 1: Trauma System Development
• Strategy 2: Quality Improvement
• Strategy 3: Trauma and Non-Trauma Center Engagement
• Strategy 4: Injury Prevention Programming

This request for application (RFA) is designed for all interested entities wishing to submit proposals for trauma system development under the core strategies outlined above. Funding decisions for all proposals submitted under this program will be made following a review process by the Indiana Trauma Care Commission (TCC) and IDOH.

The Indiana Department of Health Trauma System Development Grant supports initiatives aimed at enhancing the statewide trauma care system. Funded by the Indiana Clinical and Translational Sciences Institute, this grant encourages projects that focus on trauma system development, quality improvement, engagement with trauma and non-trauma centers, and injury prevention programming. Applicants are encouraged to submit proposals addressing one or more of these strategies to improve patient outcomes and save lives across Indiana.

The Mighty Money Mini Grant from the AWS Foundation aims to empower individuals with intellectual, developmental, and physical disabilities in Northeast Indiana. By providing quick funding to 501(c)(3) organizations, this initiative supports innovative ideas that enhance community inclusion, education, and accessibility. The grant focuses on initiatives such as social enrichment, education, transportation, early diagnosis, and housing, ensuring that these individuals can live independently and thrive within their communities.

The Myron and Patsy Pattison Scholarship supports outstanding college freshmen from Montgomery County, Indiana, aiming to assist their transition into sophomore year. Established by local philanthropists, this scholarship emphasizes academic excellence and leadership. Eligible candidates must have graduated from a public high school in Montgomery County and maintain a minimum GPA of 3.00. The award is non-renewable and aims to encourage post-graduate studies.

The Norfolk Southern Corporate Giving: Thriving Communities Grant Program supports initiatives that promote sustainability, workforce development, and community resilience across a 22-state network. With grants ranging from $1,000 to $50,000, the program aims to foster economic development and ensure equal access to basic necessities. Eligible organizations include tax-exempt nonprofits, government entities, and public schools, emphasizing diversity and inclusion in their community-focused efforts.

Funded by the U.S Department of Health and Human Services, the Social Services Block Grant (SSBG) program works to assist residential domestic violence programs in providing emergency shelter to survivors of domestic violence and their dependents. The goal of the program is to help offset the cost of certain operational expenses to include housing, food and other basic necessities in order to give domestic violence shelters more flexibility and the potential to expand services in other areas, based on their needs.

ICJI awards SSBG dollars to supplement federal Family Violence and Prevention Services Act (FVPSA) grants and state Domestic Violence Prevention and Treatment (DVPT) grants, supporting comprehensive initiatives that address the needs of domestic violence victims in Indiana. SSBG funding is distributed to emergency domestic violence programs that provide emergency shelter services in the form of overnight shelter and congregate meals.

A “shelter night” is considered a unit rate for the indirect and direct costs expended per night, per client in the shelter facility. SSBG funding is the only funding source provided by ICJI that is solely dedicated to supporting domestic violence programs’ emergency shelter operations.

The Reach Your Potential STEM Scholarship, provided by the Hamilton County Community Foundation, aims to empower Indiana students by facilitating access to educational opportunities in STEM fields. This scholarship targets current high school seniors facing financial need and encourages community involvement. Eligible candidates must be Indiana residents for eight years, demonstrate academic commitment, and pursue degrees in science, technology, engineering, or mathematics. This initiative not only fosters individual growth but also strengthens the community as a whole.

The IU Health Values Fund Grant Pilot & Feasibility Program: Education aims to advance the development of healthcare professionals through innovative educational models. By focusing on critical areas such as healthcare disparities, rural health, and behavioral health, this initiative supports the continuous training of providers. The Indiana Clinical and Translational Sciences Institute (CTSI) leads this effort to ensure that the workforce is equipped to meet evolving healthcare needs and improve patient outcomes.

Bell's Brewery Small Grassroots Grants support projects focusing on water stewardship across the Great Lakes watershed. With grant amounts ranging from $500 to $5,000, eligible organizations can apply for funding to improve ecosystem health, enhance public health through better water resource management, and promote resilience against climate-related water risks. This initiative highlights Bell's commitment to environmental stewardship and community support in all 50 states and DC.

The Terry L. Hunsucker Scholarship, established by a Winchester native, aims to support graduates of Winchester Community High School pursuing a four-year degree. Offered by the Central Indiana Community Foundation, the scholarship prioritizes students demonstrating academic promise and community service. Eligible candidates may attend any Indiana college, with awards based on fund size and applicant qualifications. Strong preference is given to local students, ensuring the support of community-focused education.

About the Indiana State Department of Agriculture

The Indiana State Department of Agriculture (ISDA) was established as a state agency by the Legislature in 2005. ISDA reports to the Lt. Governor, who also serves as Indiana’s Secretary of Agriculture and Rural Development. Major responsibilities include advocacy for Indiana agriculture at the local, state and federal level, managing soil conservation programs, promoting economic development and agricultural innovation, serving as a regulatory ombudsman for agricultural businesses, and licensing grain firms throughout the state.

Resilient Food Systems Infrastructure (RFSI) Grant Program

The Indiana State Department of Agriculture (“ISDA”), Division of Economic Development is seeking applications for the Indiana Resilient Food Systems Infrastructure Grant Program (RFSI) to carry out projects that enhance the resilience of middle-of-the-food-supply-chain.  Applicants/Grantees applying for infrastructure program funding are permitted to claim indirect costs under the RFSI Program, not to exceed the 10% de minimis cap. Applicants/Grantees applying for special equipment-only funding are not eligible to claim indirect costs. ISDA encourages applications from woman or veteran owned businesses, socially disadvantaged businesses and historically underserved farmers, ranchers, and underserved communities.

Grant funding may not be used on meat, poultry, wild caught seafood, food for animal consumption or dietary supplements. If these items are included in your project, your project must clearly define what percentage of your project will include these items and you must be able to demonstrate that no grant or matching funds are used for those portions of the project.

Projects must choose ONE of two project options: Option 1- Special Equipment Only; Option 2- Infrastructure Projects. You may not do both project options.

Option 2- Infrastructure Projects

For this project pathway, grant funding requests must be between $100,000 and $3 million. Matching funds of 50% of the total project cost are required unless the applicant qualifies as a Historically Underserved Farmer or Rancher by the USDA standards or a Socially Disadvantaged Business, Women Owned or Veteran Owned business by SBA standards (See Section A for definitions), then you qualify for a 25% match of the total project cost. Infrastructure projects may include, but are not limited to: construction, transportation, equipment, training, renovation, or expansion. Please contact ISDA if you have questions regarding eligibility of your infrastructure project.

About the Indiana State Department of Agriculture

The Indiana State Department of Agriculture (ISDA) was established as a state agency by the Legislature in 2005. ISDA reports to the Lt. Governor, who also serves as Indiana’s Secretary of Agriculture and Rural Development. Major responsibilities include advocacy for Indiana agriculture at the local, state and federal level, managing soil conservation programs, promoting economic development and agricultural innovation, serving as a regulatory ombudsman for agricultural businesses, and licensing grain firms throughout the state.

Resilient Food Systems Infrastructure (RFSI) Grant Program

The Indiana State Department of Agriculture (“ISDA”), Division of Economic Development is seeking applications for the Indiana Resilient Food Systems Infrastructure Grant Program (RFSI) to carry out projects that enhance the resilience of middle-of-the-food-supply-chain.  Applicants/Grantees applying for infrastructure program funding are permitted to claim indirect costs under the RFSI Program, not to exceed the 10% de minimis cap. Applicants/Grantees applying for special equipment-only funding are not eligible to claim indirect costs. ISDA encourages applications from woman or veteran owned businesses, socially disadvantaged businesses and historically underserved farmers, ranchers, and underserved communities.

Grant funding may not be used on meat, poultry, wild caught seafood, food for animal consumption or dietary supplements. If these items are included in your project, your project must clearly define what percentage of your project will include these items and you must be able to demonstrate that no grant or matching funds are used for those portions of the project.

Projects must choose ONE of two project options: Option 1- Special Equipment Only; Option 2- Infrastructure Projects. You may not do both project options.

Option 1- Special Equipment Only

For this project pathway, grant funding requests must be between $10,000 and $100,000. The only eligible expense in the budget for this project is the special equipment to be purchased. The equipment does not have to be American made and can be a used piece of equipment as long as the equipment is in good, working order. You may not include training for the piece of equipment in the budget. You may include installation of equipment if it is included in the quote and does not require construction of the space the equipment will be placed in. Matching funds are not required for Special Equipment Only projects. 

INDOT Mission

Together, we plan, deliver, and maintain a safe, efficient, and innovative transportation system that:

• Enhances the daily lives of Hoosiers.
• Strengthens Indiana’s economy
• Embraces evolving transportation needs.

Rural Transit Programs

Purpose

The Federal Section 5311 Program was created to provide public transportation in non-urbanized areas (population of 50,000 or less). The purpose of the program is to provide transportation to people living in rural areas. The Federal Section 5311 Program supports rural public transportation through operating, capital, and intercity transit funding.

Capital Project Grants

Capital projects generally include expenses for purchasing vehicles, communication equipment, fare boxes, passenger shelters, and construction of and rehabilitation of transit facilities. Section 5311 capital assistance may fund up to 80 percent of the total capital costs.

INDOT Mission

Together, we plan, deliver, and maintain a safe, efficient, and innovative transportation system that:

• Enhances the daily lives of Hoosiers.
• Strengthens Indiana’s economy
• Embraces evolving transportation needs.

Rural Transit Programs

Purpose

The Federal Section 5311 Program was created to provide public transportation in non-urbanized areas (population of 50,000 or less). The purpose of the program is to provide transportation to people living in rural areas. The Federal Section 5311 Program supports rural public transportation through operating, capital, and intercity transit funding.

Operating Project Grants

Operating Grants provide assistance for the operations of the transit service. Section 5311 may fund up to 50 percent of the net operating costs.

INDOT will make Section 5311 funds available for operating expenses, which generally include salaries and wages, fringe benefits, purchase of transit service contracts, fuel, oil, lubricants, replacement parts, tires, vehicle insurance, licenses, and other expenses.

Indiana Criminal Justice Institute

The Indiana Criminal Justice Institute (ICJI) is the state planning agency for criminal justice, juvenile justice, traffic safety and victim services. The institute develops long-range strategies for the effective administration of Indiana's criminal and juvenile justice systems and administers state and federal funds to carry out these strategies.

Through the use of evidence-based decision-making, ICJI works to improve the efficiency of the criminal justice system, from calls for service through post-conviction. The agency accomplishes this by bringing together key leaders from the criminal justice system at the state, local, and national levels to identify critical issues facing Indiana. The agency evaluates policies, programs, and legislation designed to address these issues. ICJI is designated as the State Administering Agency for distribution of federal funds, and as the State Statistical Analysis Center for research.

Family Violence Prevention and Services Act

The Family Violence Prevention and Services Act (FVPSA) authorizes the FVPSA grant program, which is administered by the Department of Health and Human Services (HHS), Administration for Children and Families (ACF), Office of Family Violence Prevention and Services (OFVPS). FVPSA funds are designed to assist states in their efforts to support the establishment, maintenance, and expansion of programs and projects to 1) prevent incidents of family violence, domestic violence, and dating violence; 2) provide immediate shelter, supportive services, and access to community-based programs for victims of family violence, domestic violence, or dating violence, and their dependents; and 3) provide specialized services for children exposed to family violence, domestic violence, or dating violence, including victims who are members of underserved populations.

All grants from ICJI Victim Services are reimbursement grants.

The NAACP X Society Awards Scholarship

The NAACP x Society Awards Scholarship is one of many funding opportunities available to students through NAACP's Inspire Initiatives. We offer scholarships to outstanding and qualified students pursuing undergraduate degrees. Through the generosity of our donors, we advance efforts to ensure equity in educational opportunity that prepares students for success in school, work, and life.

Scholarship amount: $1,000 to $5,000

This is a non-renewable scholarship opportunity.

The River & The Rock Award, offered by the Muscular Dystrophy Family Foundation (MDFF), provides up to $2,500 to individuals in Indiana diagnosed with muscular dystrophy or a neuromuscular disease. This award encourages resilience and perseverance, assisting recipients in pursuing their dreams and goals. Eligible applicants must demonstrate courage and complete the enrollment process with MDFF. Since its inception in 1958, MDFF has been dedicated to enhancing the quality of life for those facing neuromuscular challenges.