Best Operating Grants for Nonprofits in Indiana

The Forecast for Clinical Trial Readiness for Rare Diseases (R21) aims to enhance the development and testing of diagnostics and therapeutics for rare diseases. This funding opportunity invites researchers to facilitate clinical trial readiness by developing rigorous biomarkers and clinical outcome measures. Through collaborative efforts with various stakeholders, NCATS seeks to improve the efficiency of moving candidate therapeutics towards clinical trials, ultimately increasing the likelihood of successful treatments for rare diseases.

The Shared Decision Making in Hemophilia Patient Care grant program, funded by Pfizer, aims to enhance patient outcomes through Quality Improvement projects that integrate shared decision-making tools into hemophilia care. This initiative encourages multidisciplinary collaboration to address healthcare disparities and empower patients in their disease management. Eligible organizations include healthcare institutions and professional schools, fostering innovative approaches to improve care for individuals living with hemophilia.

The AAFP Foundation's Center for the History of Family Medicine Oral History Grant offers up to $3,000 annually for oral history interviews in family medicine. Aimed at researchers, physicians, and students, it encourages the documentation of family medicine's history in the U.S. The grant supports travel and research expenses to enhance the oral history collection, ensuring a diverse representation of experiences and perspectives in the field.

The AMVETS Veteran, Active Duty & Guard/Reserve Scholarship provides financial assistance up to $12,000 for qualified U.S. Veterans and active military members pursuing undergraduate degrees. This scholarship is designed to bridge the financial gap after all other federal and state aid has been utilized. Eligibility includes being an honorably discharged veteran or active service member, enrolled in an accredited institution, and demonstrating financial need. AMVETS is dedicated to serving those who have served our country.

The AMVETS Spouse Scholarship offers financial support to the spouses of honorably discharged veterans and active military personnel, including National Guard and Reserves. This scholarship aims to bridge financial gaps after other federal and state resources have been exhausted. Eligible applicants must be U.S. citizens enrolled in accredited undergraduate programs, demonstrate financial need, and not be in default on federal student loans. AMVETS stands committed to empowering military families through education.

The CIRI Foundation, established in 1982, promotes education and economic self-sufficiency for Alaska Natives through scholarships like the Cap Lathrop Scholarship. This award offers up to $2,000 to full-time students pursuing degrees in fields such as business, engineering, and media. Eligible applicants must be Alaska Native shareholders or descendants, maintain a minimum 3.0 GPA, and intend to work in Alaska's broadcast industry. The scholarship supports both educational and personal expenses.

The Achievement Annual Scholarship, offered by the CIRI Foundation, supports Alaska Native students pursuing higher education. This merit-based scholarship awards up to $8,000 for one academic year, covering direct educational costs and personal expenses. Applicants must maintain a minimum 3.0 GPA and be enrolled full-time in a 4-year undergraduate or graduate program. The scholarship aims to promote academic excellence and career development while honoring the cultural legacy of Alaska Natives.

The Chicago Innovation Awards celebrate outstanding innovations developed in the Chicago region over the past four years. This initiative, backed by the Chicago Innovation Foundation, fosters a vibrant ecosystem through education and connection among innovators. Key awards include the People's Choice Award and the Climate Champion Award, recognizing diverse contributions. Organizations are encouraged to self-nominate, promoting inclusivity and engagement in the innovation landscape. This event aims to inspire and acknowledge impactful solutions that drive positive change.

This grant opportunity invites applications for Large Health Services Research Demonstration and Dissemination Projects aimed at combating antibiotic-resistant bacteria (CARB). The projects should focus on promoting the appropriate use of antibiotics, minimizing the transmission of resistant bacteria, and preventing healthcare-associated infections (HAIs). Applications must be submitted by 5:00 PM local time of the applicant organization, as specified in the announcement.

This grant opportunity supports large-scale research projects aimed at combating antibiotic-resistant bacteria (CARB). It focuses on promoting the appropriate use of antibiotics, reducing the transmission of resistant strains, and preventing healthcare-associated infections (HAIs). Funded by the US Department of Health and Human Services' Agency for Healthcare Research and Quality (AHRQ), this initiative encourages innovative approaches to address these critical public health challenges.

The Steve Sullivan Professional Development Funding Grant, offered by the REALTOR® Foundation, aims to enhance the capabilities of 501(c)(3) non-profit organizations in central Indiana. With a commitment to combating homelessness, the grant provides resources for training in essential areas such as grant writing, leadership, and strategic planning. By focusing on professional development, the Foundation seeks to empower organizations to better serve vulnerable populations and create sustainable solutions for housing instability.

The New Music Organization Fund Grant supports non-profit organizations and performance groups dedicated to promoting new music and nurturing creators. This grant prioritizes artistic merit, community impact, immediate funding needs, and a commitment to inclusion. Eligible entities can apply for assistance to sustain their vital programming and resources for artists, ensuring the continued development of a vibrant music community.

The Retail Food Safety Regulatory Association Collaboration program supports state, local, tribal, and territorial (SLTT) food safety initiatives to mitigate food-borne illness risks. Funded by the FDA, this initiative aids SLTT agencies in research and intervention implementation, aiming to enhance public health and establish a cohesive national food safety framework. Eligible applicants include non-profit organizations connected to higher education institutions, focusing on retail food safety.

The Equus Veterinary Research Fellowship, established by the Equus Foundation and The Foundation For The Horse, offers a $5,000 scholarship and a $500 travel stipend to support equine research. Open to graduates of AVMA-accredited veterinary schools nearing residency or doctoral completion, this fellowship encourages innovative research in horse health care. Applications are accepted from mid-July to August, promoting the advancement of equine veterinary practices and the training of future researchers.

The Posey County Lilly Endowment Community Scholarship Program aims to enhance educational attainment in Indiana by providing scholarships for full tuition and fees for eligible students. Administered locally by community foundations, it supports those graduating from accredited Indiana high schools and encourages students to engage with their communities. Scholars receive financial assistance for books and equipment, fostering academic success and collaboration with local leaders, thereby improving overall quality of life in Indiana.

The Seymoure, Fred and Mildred (Young) Memorial Scholarship Fund offers a $500 scholarship to a Central Noble High School senior or graduate, or a resident of the Albion area pursuing a BS or MS in education. Established by the Noble County Community Foundation, this fund aims to support future educators in making a positive impact in their communities. Since 1991, the foundation has been dedicated to enhancing the quality of life in Noble County.

The USS ST. LOUIS (LCS 19) Scholarship, established by the Commissioning Committee in 2020, supports crew members and their dependents pursuing undergraduate degrees or technical training. Administered by The Scholarship Foundation of St. Louis, it awards up to $12,000 annually, renewable for up to ten semesters. This initiative honors the commitment of the USS ST. LOUIS crew while fostering educational advancement and community engagement.

The Terre Haute Day Nursery Endowment Fund Grant, offered by the Wabash Valley Community Foundation, aims to support quality childcare through program development and equipment funding. The foundation encourages impactful proposals that demonstrate measurable outcomes, collaborative efforts, and community commitment. While operational expenses and religious purposes are generally excluded, projects focused on enhancing childcare services for the community are welcomed. This initiative seeks to create lasting, positive changes in childcare accessibility and quality.

The Leaman, Pauline (McClish) Scholarship Fund, established by Will Leaman in memory of his wife, aims to support West Noble High School seniors pursuing education, especially in math. With a one-time award of $1000, this fund highlights the Community Foundation of Noble County's commitment to enhancing local education and fostering future teachers. It embodies the foundation's mission to drive positive change and improve the quality of life in Noble County through philanthropic efforts.

The Cromwell-Kimmell Lions Club Fund, established by community member Carol Stults, aims to provide scholarships for West Noble Seniors. This fund is part of the Noble County Community Foundation's mission to enhance the quality of life in the region. The Lions Club engages in various community activities, including fundraisers and training youth through the Leo Program. By supporting this fund, donors contribute to positive change and educational opportunities for local students.

The Terry Farrell Firefighters’ Fund, established post-9/11, provides vital educational and financial support to families of firefighters across the U.S. With over $10 million distributed in grants and surplus gear, the fund offers scholarships, emergency assistance, and training for first responders. It also supplies rural fire departments with necessary equipment and sponsors health initiatives like blood and bone marrow drives, ensuring comprehensive support for those who serve our communities.

The ACS - Fanconi Cancer Foundation Discovery Boost Grant invites innovative proposals for translational cancer research addressing the challenges faced by individuals with Fanconi anemia (FA). This grant supports high-risk, high-reward projects aimed at improving detection, prevention, or treatment of FA-related cancers. With funding of up to $135,000 per year for two years, it encourages research in early detection technologies, prevention mechanisms, and therapeutic strategies tailored to the unique sensitivities of the FA population.

The OCCF Teacher Mini-Grants Program, established in 1997, offers grants ranging from $50 to $300 for Spencer-Owen School Corporation teachers to enhance classroom learning. Grants can fund materials, assemblies, and collaborative projects, and are awarded on a first-come, first-served basis. Each teacher can apply for one grant annually, with the option to team up with colleagues for larger projects. This initiative, created by educators for educators, aims to enrich student experiences.

The Rural Health Fellows Leadership Program, offered by the National Rural Health Association (NRHA), is an intensive yearlong initiative aimed at cultivating a diverse network of rural health leaders. Selected participants engage in leadership training, policy advocacy, and collaborative projects. The program includes monthly virtual sessions, in-person meetings at key conferences, and opportunities for financial support, thereby empowering fellows to make a significant impact on rural healthcare.

The IATSE Local 600: Traditional Hardship Fund Grant provides emergency financial assistance to performing arts and entertainment professionals in times of unexpected need. This grant supports basic living expenses like healthcare and housing, aiming to prevent eviction or shut-offs. Eligible members must have been in good standing for at least two years and have faced work loss due to illness or disasters. The fund ensures support during critical times, promoting stability within the community.

The IATSE Local 700 Hardship Relief Fund provides emergency financial assistance to eligible members of the performing arts and entertainment industry during critical times. This support helps cover essential living expenses, such as housing and healthcare, to prevent eviction and utility shut-offs. To qualify, members must have met minimum dues requirements or be officially retired. The fund does not cover expenses like credit cards, loans, or business-related costs.

The Harry A. Saunders III Memorial Fund, established in 2025 by the Hawai‘i Community Foundation, supports Hawaii high school graduates pursuing higher education. This fund aims to empower students demonstrating financial need and maintaining a minimum GPA of 2.0. Preference is given to recipients who were awarded in the previous year, provided they continue to meet eligibility requirements. The fund embodies a commitment to fostering educational opportunities and enriching the lives of young Hawaiians.