Best Indianapolis Grants for Nonprofits in Indiana

The Critical Needs List by Community Foundation Tampa Bay addresses urgent, unforeseen needs of nonprofits that threaten their ability to serve the community. This innovative program allows nonprofits to submit requests for funding up to $250,000 for critical expenses such as emergency repairs and essential equipment replacement. With a focus on supporting local organizations, the program aims to match funding with community philanthropists, ensuring timely assistance to those in need.

The Economics program by the National Science Foundation supports research to enhance understanding of the U.S. economy and global systems. It prioritizes interdisciplinary studies and encourages diverse proposals, including those from junior faculty and underrepresented groups. Funding opportunities range from individual projects to doctoral dissertation improvement grants, emphasizing rigorous economic analysis and data collection. The program aims to strengthen links between economics and other disciplines, fostering innovative research in various economic subfields.

The National Center for Construction Safety and Health Research and Translation (U54) aims to enhance worker safety in the construction industry through innovative research and intervention strategies. By fostering partnerships and focusing on evidence-based solutions, the Center will address critical safety and health challenges faced by construction workers. The initiative aligns with NIOSH's strategic objectives, promoting collaboration among academic institutions and organizations to improve health outcomes and reduce the occupational health burden in this vital sector.

The Music Man Foundation invites eligible organizations to apply for Advocacy and Research Grants aimed at supporting systemic change in the arts sector. Organizations must demonstrate their impact on music-related systems, showcase their priorities in the field, and outline their achievements. Grants will assist with research, advocacy training, and cross-sector initiatives to enhance community vitality and promote sustainable solutions, reflecting the Foundation's commitment to fostering positive arts engagement.

The National Meredith Willson Awards provide multi-year operating support to organizations using music for systemic change. The Music Man Foundation will award grants of $50,000 to $500,000 to 5-10 selected organizations in 2026, focusing on their impact through music. Eligible organizations must have 501(c)(3) status, a history of music programming, and a commitment to systemic change. Applications will be evaluated on leadership, organizational capacity, and alignment with grant criteria.

The Electronics, Photonics and Magnetic Devices (EPMD) Program, funded by the National Science Foundation, promotes cutting-edge research on innovative devices utilizing electronics, photonics, and magnetics. The program aims to enhance micro-, nano-, and quantum-based technologies across diverse fields such as healthcare, energy, and communications. EPMD emphasizes the importance of novel materials and energy-efficient designs, fostering advancements that ensure improved functionality and reliability in future applications.

The Joyce Foundation's Education & Economic Mobility Grants aim to close income and race disparities in college and career success. The foundation prioritizes equitable access to high-quality education, supporting policies for effective educators, high school graduation, and affordable college credentials. Focused on racial equity and economic mobility, it addresses the needs of historically underserved young people in the Great Lakes region and invests in research, policy development, and advocacy to help them recover from the COVID-19 pandemic.

The NDEP STEM Open NFO invites innovative proposals for research and implementation of effective STEM education and outreach programs. This continuously open announcement from the Department of Defense encourages submissions that align with key initiatives, including support for community colleges and strategic partnerships. As funding becomes available, amendments detailing specific topics and submission guidelines will be released. Applicants must submit white papers to express interest in full applications for potential funding consideration.

The National Book Fund (NBF) offers grants to support adult education and literacy programs across the U.S. by providing New Readers Press materials. Grants typically range from $500 to $2,000, with applications considered for higher amounts if justified. Eligible applicants must have a defined project and use materials directly with learners. Priority is given to nonprofit organizations providing free literacy instruction. Note that individuals and lending libraries are not eligible for funding.

The Action, Implementation, and Mitigation (AIM) Grants, offered by COCO, support organizations in enhancing wildfire risk reduction efforts. Since 2018, COCO has assisted over 90 groups, focusing on community resilience and restoration of fire-adapted ecosystems. Eligible applicants include nonprofits and local governments, with funding ranging from $10,000 to $75,000. Projects should align with broader wildfire strategies and require a 100% cash or in-kind match, promoting inclusive and effective community mitigation approaches.

The Communications, Circuits, and Sensing-Systems (CCSS) Program by the NSF funds innovative research in circuit hardware, signal processing, and system architectures. It aims to advance cyber-physical systems through cutting-edge technologies, including MEMS/NEMS and neurotechnologies. The program supports applications across diverse fields such as healthcare, environmental monitoring, and smart systems. Proposals are encouraged for high-speed communications, real-time sensing, and intelligent autonomous systems, fostering significant advancements in communication and sensing capabilities.

The Growing Research Access for Nationally Transformative Equity and Diversity program, funded by the National Science Foundation, aims to enhance the research enterprise by addressing structural barriers and promoting inclusivity. By focusing on administrative support and innovative strategies, the initiative seeks to empower diverse organizations to participate in research. Proposals should target institution-wide impacts and scalable models that strengthen human capital and research practices, fostering a more equitable and competitive research landscape.

The It Gets Better Project is offering 50 grants of up to $10,000 each to public and charter schools across the U.S. to enhance inclusivity for LGBTQ+ youth. Schools can propose projects such as enhancing library resources, artistic installations, or establishing support groups. The initiative aims to empower LGBTQ+ students and foster a supportive environment, ensuring that every school can participate in uplifting their communities and promoting equality.

The FY 2025 EDA Public Works and Economic Adjustment Assistance Programs aim to enhance economic growth and resilience in distressed communities. EDA invites ongoing applications for funding, focusing on innovative approaches that leverage regional strengths. The updated NOFO emphasizes timely reviews and outlines submission procedures for core programs under the Public Works and Economic Development Act. Grantees are encouraged to develop unique initiatives that foster lasting economic prosperity.

The Richard King Mellon Foundation invites innovative proposals that align with their 2021-2030 Strategic Plan, aiming to invest over $1.2 billion to enhance opportunities in southwestern Pennsylvania. Their funding focuses on conservation, economic development, economic mobility, health and well-being, organizational effectiveness, and social-impact investments. The General Application offers flexibility without deadlines, allowing for a variety of support types, including project-specific and general operating funding, aimed at enriching community vitality and environmental stewardship.

The Historically Black Colleges and Universities - Undergraduate Program (HBCU-UP) aims to enhance STEM undergraduate education and research at HBCUs. It offers various funding opportunities, including Research Initiation Awards, Targeted Infusion Projects, Implementation Projects, and Broadening Participation Research Centers, to support innovative educational goals and broaden participation in STEM fields. Proposals are due on various dates, ensuring multiple opportunities for institutions to engage with this vital funding.

The Health Information Outreach Award, funded by the National Library of Medicine, aims to enhance access to essential health information for underrepresented populations and healthcare professionals. This initiative focuses on improving health literacy and equity through diverse projects, including training, technology access, and community outreach. Eligible organizations from select Midwestern states can apply, prioritizing innovative solutions that address health disparities and promote informed health decisions among vulnerable communities.

The IAF Research Fellowship Program, administered by the Social Science Research Council, aims to support rigorous research on community-led development in Latin America and the Caribbean. The fellowship provides a $20,000 stipend for twelve months, fostering innovative solutions to pressing issues such as economic opportunity, migration, and social inclusion. Researchers are encouraged to explore how community-led models can create lasting impacts and respond to global trends, enhancing local resilience and development.

The Abbey Mural Prize, established in 1932, supports the creation and restoration of public murals across the United States. This prestigious award, administered by the National Academy of Design since 1940, emphasizes projects that enhance community engagement and social activism through art. Grants typically range from $10,000 to $40,000, with a total annual funding cap of $125,000. Eligible applicants include artists, architects, and nonprofit organizations committed to impactful mural projects.

The UEF Grant Program, offered by the United Engineering Foundation, supports innovative projects that enhance the engineering profession and public welfare. With an annual budget of nearly $800,000, the program awards 5 to 10 grants each year. Eligible applicants must be U.S.-based organizations with 501(c)(3) status. Preference is given to interdisciplinary proposals that engage the community and integrate various engineering fields, fostering collaboration and addressing important societal issues.

The SCI Research on the Translational Spectrum (SCIRTS) portfolio aims to promote innovative research that enhances function and alleviates complications following spinal cord injuries. It encourages studies that involve individuals with SCI, emphasizing translational significance in research designs. SCIRTS grants support diverse research areas, including mechanistic, preclinical, and clinical studies, to develop effective interventions. Funding categories include Postdoctoral Fellowships, Pilot Research Grants, and Senior Research Grants, targeting early-career and senior investigators to advance spinal cord injury research.

The Felix E. Martin Jr. Foundation Community Leadership Fund provides essential support for leadership development in Muhlenberg County, KY. It aims to empower individuals and groups seeking innovative solutions to local challenges. Eligible applicants include those pursuing personal leadership growth or researching effective community strategies. The fund underscores inclusivity, welcoming diverse applicants without discrimination. This initiative fosters a vibrant community by equipping leaders with the resources needed to effect positive change.

The TFish Fund Grant aims to alleviate poverty in East Asia by empowering small but impactful NGOs to achieve sustainability and transparency. Founded in 2011, the Transparent Fish Fund partners with select organizations that focus on poverty alleviation. By providing financial aid, capacity building, and promoting accountability, the fund bridges the gap between Western donors and local NGOs, fostering a philanthropic spirit while addressing the complex social issues faced in the region.

This funding opportunity aims to support Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using Nonhuman Primate (NHP) models. Eligible applicants must have at least two years of postdoctoral experience and be within ten years of their terminal degree. The initiative aligns with the NIH Strategic Plan for HIV and HIV-Related Research, targeting the reduction of HIV incidence, development of therapies, and advancement in research areas related to HIV.

The Research Experiences for Undergraduates (REU) program, funded by the National Science Foundation (NSF), promotes active research participation among undergraduate students across various research areas. It supports two mechanisms: REU Sites, which engage multiple students in ongoing research, and REU Supplements, which enhance existing NSF-funded projects. Participants must be U.S. citizens, nationals, or permanent residents, and each REU opportunity has its unique application process.

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

The Facility and Instrumentation Request Process (FIRP) enables the research community to propose projects requiring access to specialized instrumentation and facilities funded by the Facilities for Atmospheric Research and Education (FARE) Program. This solicitation offers three submission tracks: Education and Outreach, Single Facility Request, and Field Campaigns. Proposals are accepted anytime, with preference given to those submitted to programs within the Division of Atmospheric and Geospace Sciences (AGS) of the National Science Foundation.