Best Large Grants for Nonprofit Organizations in Massachusetts

The Brees Dream Foundation Grant aims to enhance the lives of cancer patients while providing essential care, education, and opportunities for children and families in need. With the support of generous donors and partners, the Foundation is dedicated to advancing cancer research and offering vital resources to those facing challenges. This commitment reflects a profound dedication to improving quality of life and fostering hope in communities.

Oncology Nursing Foundation

The mission of the Oncology Nursing Foundation is to support cancer nursing excellence.

Since 1981, the Oncology Nursing Foundation(ONF), through generous contributions from individuals and institutions, has provided more than $33 million in funding to support oncology nursing education, research and leadership development. This funding has translated to career development awards, academic scholarships, research grants, a myriad of specialized educational initiatives, as well as nurse resiliency support. The Foundation’s activities have played a critical role in improving patient care and advancing the oncology nursing profession.

Radiation Oncology Certified Nurse (ROCN™) Exam Scholarship

Recipients receive funding to cover the ONCC ROCN™ Certification exam fee.

Purpose

To support registered oncology nurses who specialize in providing care for adult or pediatric patients with cancer undergoing radiation therapy by providing funding support to cover the ROCN™ Certification exam fee. 

The William C. Risser Charitable Trust Grants support mental health research, particularly in Schizophrenia. This private foundation assists 501(c)(3) nonprofit organizations across the U.S. with grants typically ranging from $25,000 to $55,000. Administered by Wells Fargo, the Trust awards 1-2 grants annually, focusing on program support for scientific and educational research. Eligible organizations must meet IRS exemption requirements.

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Funding

• Individual projects requesting up to $50,000 USD will be considered. Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.
• Maximum project length is 1 year.

The Delta Scholarship aims to support college-bound minority students in San Diego County who are dedicated to pursuing higher education. Established in memory of Jim Lewis, a passionate community leader, this scholarship offers up to $10,000 per student annually for four years, based on financial need. Eligible applicants must be graduating high school seniors with a minimum GPA of 3.0, planning to attend an accredited college or university.

The Innovations in Alzheimer’s Caregiving Awards, overseen by the Family Caregiver Alliance, recognize organizations that enhance support for family caregivers of individuals with Alzheimer’s disease. These awards highlight innovative approaches in three categories: Creative Expression, Increasing Access and Reducing Stigma, and Public Policy. Each award is valued at $20,000, and applicants must be non-profit organizations, government agencies, or universities operating within the U.S. that focus on the needs of unpaid caregivers.

The Alma Gilmore Doud Memorial Scholarship honors a dedicated community servant from Saginaw. Established by the Saginaw Community Foundation, this scholarship supports students pursuing Career and Technical Education (CTE) programs or undergraduate degrees. Applicants must have a minimum GPA of 3.0 and reside in the Great Lakes Bay Region. Priority is given to members of the First Congregational Church. Awards typically range from $500 to $4,000, addressing the growing demand for skilled trades in today's workforce.

The ESA Youth Scholarship Program, by the Electronic Security Association, provides financial support to children of first responders, having awarded over $941,500 to date. Eligible applicants are high school seniors with parents who are full-time active first responders. Each scholarship winner receives $1,000 and a chance to compete for larger awards of $14,000 for first place and $5,000 for second place. Applications are welcomed from students in participating states.

Gregory D. Spring Perseverance Scholarship

Established in memory of Gregory D. Spring, this scholarship is for a graduating senior from Allegany-Limestone Central School, Ellicottville Central School, Franklinville/Ten Broeck Academy, Portville Central School, Hinsdale Central School or Olean High School with a preference for a student who intends to pursue a degree or certification in a trade or technical program. 

Nebraska Community Foundation

Nebraska Community Foundation was established in 1994 by a group of visionaries determined to empower communities throughout the state to grow and prosper. They believed that with the right tools and resources, people could build the hometowns of their dreams.

Through philanthropy, our team helps communities develop strong local economies, high quality of life, and abundant leadership and volunteer opportunities. We empower local leaders to identify community assets, invest in their own resources, and bring about their own positive change. 

BCAFF Scholarships

The Butler County Area Foundation Fund is offering three scholarships to graduating seniors who meet individual scholarship criteria. These scholarships are the Butler County Clinic Scholarship (medical field major); Charles O. & Grace M. Stoops Scholarship in Agricultural or Environmental Studies; and Butler County Area Foundation Fund Scholarship.

Charles O. & Grace M. Stoops Scholarship in Agricultural or Environmental Studies

• Funding for this scholarship through the Butler County Area Foundation Fund has been provided by a gift of Grace M. Stoops and the late Charles O. Stoops of Montecito, California. Scholarship funds are available for students whose major field of study is agricultural or environmental studies.

• Two $1000 scholarships will be awarded annually to resident graduates of David City High School, Aquinas High School, or East Butler High School. Additionally, a student who is a resident of Butler County who attends a school outside of Butler County, is also eligible. Each applicant may be an entering freshman or an upperclassman enrolled for post-secondary education at an accredited school of higher education in the general areas of agriculture or environmental studies.

• Each scholarship must be used at a post-secondary accredited school of higher education.

• Scholarship funds will be paid directly to the school after the student has successfully completed the first semester.

Ginger D. Schroder Cattaraugus County Legislative District 2 Scholarship

The Ginger D. Schroder Legislative District 2 Scholarship is given to a graduating high school student residing in Cattaraugus County Legislative District 2 who will pursue a trade degree or 2-or 4-year college degree.

The NIGMS Institutional Biomedical Undergraduate Research Training Program aims to enhance the training of undergraduate students in biomedical research. By supporting institutions with limited NIH funding, the program provides trainees with 2–3 years of full-time research training. This initiative fosters a skilled workforce prepared for advanced biomedical degrees, addressing national health-related research needs through comprehensive educational and developmental programs.

The CareQuest Institute for Oral Health® is inviting proposals for school-based and school-linked initiatives aimed at improving oral health access for high-risk children. This grant opportunity seeks to address systemic barriers to oral health through innovative programs that engage schools and communities. Ideal projects may include workforce development, community engagement strategies, policy advocacy, and the use of technology. Proposals should focus on creating equitable oral health solutions that enhance both health and academic success for children and their families.

The MASOT Conney W. Berger Jr. Memorial Graduate Student Award, established in honor of a dedicated toxicologist, supports doctoral students in toxicology/pharmacology. Eligible candidates must present at the MASOT meeting and meet specific criteria, including GPA requirements and MASOT membership. This award, valued at $500, encourages academic excellence and is made possible through the generous support of SafeBridge Consultants, Inc.

The Cultural Capital Fellowship offers $10,000 grants to Native artists and culture bearers dedicated to community outreach and cultural preservation. This fellowship strengthens the Collective Spirit of First Peoples artists, emphasizing the importance of passing on ancestral knowledge and maintaining cultural sharing. Eligible applicants must have strong ties to their Native community and be committed to sustaining cultural practices. The fellowship aims to support those who promote generosity, wisdom, and integrity within their communities.

The Jennifer Easton Community Spirit Award honors Native artists who have dedicated their lives to sharing cultural knowledge and ancestral gifts. With a grant of $50,000, this award supports artists deeply rooted in their communities, fostering healing and resilience. Nominations are open for practicing artists across various mediums, including music, dance, and storytelling, ensuring the continuation of Indigenous traditions and the enrichment of Native culture.

The Native Performing Arts Fellowship (NPA) supports Native artists in enhancing their craft through grants of up to $10,000. This fellowship prioritizes personal artistic development over project-based funding, encouraging applicants to focus on growth through classes, workshops, and professional mentorship. Eligible candidates must be U.S.-based, 18 years or older, and enrolled members of recognized tribes. The program emphasizes Indigenous values in performing arts, fostering resilience and cultural expression.

The African-American Community Foundation - Major John F. Harris, Jr., Memorial Scholarship aims to support JROTC graduates from Dayton Public Schools in pursuing higher education. Established by The Dayton Foundation, it honors Major John Harris, Jr., a dedicated instructor who inspired students to achieve independence. Eligible applicants must demonstrate leadership and be accepted into accredited educational institutions. This scholarship reflects the Foundation's commitment to enhancing educational opportunities and empowering youth in the Greater Dayton area.

Building Capacity for Communicating Impact Learning Community RFA

Learn how to communicate about Public Health Infrastructure Grant impact through a new community of practice! Through peer learning, technical assistance, and practical tools, participating teams will build strategic leadership and communications skills to more effectively translate public health achievements into compelling messages for key audiences. All directly funded PHIG recipients (big-city, county, state/territory-level governmental public health professionals) are eligible to apply.

The Ollie Hinkle Heart Foundation's Technology Grant aims to improve pediatric heart care outcomes through innovative collaborations. By focusing on predictive technologies for early recognition, precision for personalized care, and preventive measures for quality of life, the foundation seeks to transform care for heart children and their families. Their mission emphasizes community support, education, and advocacy to ensure no family faces unmet needs alone, creating a legacy of love and courage in the heart community.

Jack Beaty Educational Scholarship Foundation Grant

Jack Beaty was a pillar of the community he lived in and loved. He was a successful businessman from an early age having founded two companies. One company supplied food to retail stores throughout New Mexico, where Jack became friends with all his customers and fell in love with the state. He founded an oil and gas company in Farmington, New Mexico as well.

Jack eventually became involved in politics in New Mexico where he served as the Bernalillo County Democratic Chairman and the New Mexico State Democratic Chairman. During the 1960 Presidential campaign, Jack became friends with John F. Kennedy and Robert Kennedy. Jack served as the Western States coordinator for the Kennedy campaign. After the 1960 election, Jack sold his food supply business and moved to Washington, D.C. Jack served in both the Kennedy and Johnson Administrations. Following this service, Jack formed the public relations firm Jack Beaty and Associates in Washington, D.C.

While in Washington, D.C., Jack met and married Rose Marie Beaty Martinez, the personal assistant to Senator Joseph M. Montoya, the United States Senator from Mexico. Jack and Rose Marie retired to New Mexico in 1979 where Jack devoted his time to managing Western Minerals and Oil. Jack desired that upon his and Rose Marie’s death that his estate be used to assist and provide access to education to less fortunate students in New Mexico.

In his estate plan, Jack desired that the Jack Beaty Educational Scholarship Foundation be established to carry out his charitable goal of assisting students to obtain a secondary education.

The VFW's Sport Clips Help A Hero Scholarship offers financial support of up to $5,000 to eligible veterans and service members pursuing their educational goals. This initiative, backed by the Veterans of Foreign Wars organization, aims to alleviate the burden of student debt for those who have served our country. By partnering with Student Veterans of America and Sport Clips, the VFW ensures that veterans receive the assistance they deserve to succeed in their academic endeavors.

The ASF Family Fund Grant, offered by the Angelman Syndrome Foundation, provides crucial financial assistance to families of individuals with Angelman syndrome. This rare neuro-genetic disorder affects approximately 500,000 people globally. The fund aims to enhance the quality of life for affected individuals, allowing caregivers to apply for up to $5,000 to cover essential needs. Limitations include restrictions on certain expenses and prior grant awards. This initiative aims to support families through education and necessary resources.

The CFF/NIH R01-Unfunded Award, offered by the Cystic Fibrosis Foundation, supports exceptional CF-related research projects that have been submitted to NIH but lack funding. This program aims to bridge the gap for meritorious projects, providing up to $125,000 per year for two years. By facilitating research in cystic fibrosis, the foundation helps ensure that innovative ideas can continue to progress toward improving care and outcomes for individuals affected by this disease.

The CF Foundation/NIH K-Unfunded Award aims to support exceptional research projects in cystic fibrosis (CF) that have been approved by the NIH but lack funding. This award provides temporary financial assistance of up to $80,000 per year for two years to ensure that promising CF research continues without interruption. The initiative focuses on fostering a new generation of researchers dedicated to advancing CF studies while encouraging the NIH to provide long-term support.

The Cystic Fibrosis Foundation's Student Traineeship Award supports students in engaging with cystic fibrosis research through hands-on projects. With a maximum funding of $4,000 for one year, the program aims to inspire students to pursue careers in CF research or care. Eligible applicants must be enrolled in a degree program and collaborate with a faculty mentor on a relevant project. This initiative also emphasizes the importance of maintaining interest in CF-related research among new generations.

The Cystic Fibrosis Foundation offers a Travel Award Supplement aimed at supporting Ph.D. students, postdoctoral fellows, and junior faculty. This funding of up to $3,000 enables trainees to participate in off-site workshops or training programs to enhance their research skills. Eligible applicants must be active researchers in CF projects, with a minimum of one year of experience. The program excludes conference attendance and for-profit entities, ensuring focused support for advancing cystic fibrosis research.