Best Large Grants for Nonprofit Organizations in Massachusetts

The Small Business Transition Grant for New Entrepreneurs supports new investigators transitioning into entrepreneurship, particularly in small business settings. This NIH initiative aims to bolster their development as Program Directors or Principal Investigators while fostering their research and entrepreneurial skills. By promoting training and mentorship, this grant encourages the growth of promising technologies that align with NIH's mission to enhance health and save lives. Applications are due by 5 PM local time, with optional Letters of Intent recommended 30 days prior.

City of Boston Office of Historic Preservation

The Office of Historic Preservation promotes and protects the City of Boston's cultural heritage. Part of the Environment, Energy and Open Space Cabinet, the department houses the Boston Landmarks Commission, the City Archaeology Program, and the Commemoration Commission.

Historic Marker Community Grants

Browne Fund grants supporting community research and proposals for permanent historic markers by Boston's Office of Historic Preservation.

In honor of the nation's 250th anniversary in 2026 and the city's 400th in 2030, the Edward Ingersoll Browne Fund is opening a special grant round.

The Browne Fund requests proposals from nonprofit organizations with experience in community engagement and historic documentation to research and propose potential historic markers in Boston.

These small grants ($7,500 per organization) will support the following scope of services:

• Community engagement;
• Research and documentation of a minimum of ten (10) possible historic markers; and
• Preparing and submitting at least one application to the Boston Historic Markers Program for consideration for a permanent marker.

Please note, all proposals will need to address the full scope of services.

The FY 2027 DoN HBCU/MI Program aims to enhance the research capabilities of Historically Black Colleges and Universities and Minority Institutions. This initiative promotes innovative solutions to naval science challenges while engaging students and faculty in STEM fields. Key objectives include strengthening research infrastructure and fostering collaborative efforts across institutions. White papers are due by September 18, 2026, and should clearly outline the proposed advancements in naval-relevant science and technology.

The Small Business Transition Grant for New Entrepreneurs, funded by the NIH, supports new investigators in entrepreneurship. This grant aims to enhance the entrepreneurial skills of researchers while facilitating their research and development efforts in small businesses. It encourages the employment of Program Directors/Principal Investigators (PDs/PIs) who possess strong scientific expertise but limited entrepreneurial experience, fostering innovation aligned with NIH's mission to improve health and save lives.

About Americans for the Arts

Building Collective Power for the Arts

Americans for the Arts is the nation's leading arts advocacy organization. We mobilize advocates, produce trusted research, and secure bipartisan wins that protect funding and expand arts access nationwide — work we've been doing for more than 65 years.

Americans for the Arts advances the people, organizations, and systems supporting arts and culture across America through advocacy, research, and national convening.

We envision a nation where freedom of creative expression is upheld as a fundamental human right, where arts and culture are woven into the fabric of civic life, resourced in every community, and accessible to everyone.

Request for Proposals (RFP)

Strengthening Leadership Capacity of Local Arts Agencies

Given the essential role of LAAs, and to meet this important moment, AFTA seeks an energized and experienced consulting team with expertise to help it develop a comprehensive strategy to strengthen leadership and field capacity across the LAA ecosystem. This work is not intended to operate in isolation, but rather to complement and build upon existing efforts already underway in the field. The focus is on identifying where AFTA can add value through targeted, strategic support that enhances and aligns with broader sector-wide initiatives. 

This effort will focus on empowering LAA agency leaders—a critical component of AFTA’s strategic direction—to expand their capacity, foster innovation, and advance equity in a rapidly evolving environment. Building on existing efforts across the field, AFTA will invest in strong, effective LAA leadership, broaden cultural access and participation nationwide, and position the field for a more vibrant, resilient, and sustainable future. 

With approximately 2,200 LAAs nationally validated in AFTA’s LAA Wayfinder, the selected consulting team will help AFTA gain a deeper understanding of the gaps, needs and opportunities shaping LAA leadership capacity, with attention to Native, rural, small, midsize, and large communities, and identify where AFTA is uniquely positioned to contribute. These insights will guide AFTA’s future direction in its service to LAAs nationwide and ensure AFTA’s contributions complement—rather than duplicate—the work of other entities, collectively strengthening the broader LAA ecosystem.  

In addition, by intentionally working in partnership with peer organizations and stakeholders across the field—and by understanding gaps in coverage and opportunities for growth—AFTA will be positioned to work with partners to support the expansion of the LAA network in communities where local public cultural infrastructure is limited or absent. This collaborative approach will help ensure more equitable access to arts and culture while reinforcing the role of LAAs as essential community anchors, particularly in underserved regions. 

Arnold Ventures

Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of Americans through evidence-based policy solutions that maximize opportunity and minimize injustice. We focus on improving systems where outcomes are falling short, incentives are misaligned, and the time is right for change.

To advance this mission, we invest in rigorous research to better understand the root causes of problems and strengthen the evidence base on what works to solve them. Using this evidence, we advocate for policy reforms at all levels of government and help build durable, bipartisan coalitions for lasting change.

Causal Research on the Impacts of Cell Phone Policies in K-12 Schools

The Opportunity

Smartphones are nearly universal among children and adolescents in the United States: 95% of teens reported having access to a smartphone, giving them regular exposure to social media, gaming, and video streaming platforms. While smartphones can support learning and social connection, emerging evidence suggests that using phones during school may also interfere with important educational goals, including student engagement, attendance, and academic performance.

In response, more than 30 states have passed laws restricting cell phone use in K-12 schools in recent years. These policies vary widely, ranging from “bell-to-bell” policies to classroom-level bans on phones only during instructional time. Despite the rapid adoption of these policies, rigorous evidence on academic, behavioral, and mental health impacts remains limited. In the absence of strong research, federal and state policymakers, as well as school and district leaders, lack the information needed to make informed decisions that effectively support student success. Building a robust evidence base is critical for shaping policies and practices that improve learning and well-being in both the short- and long-term.

This RFP seeks to address these gaps by supporting rigorous, causal research on the academic, behavioral, and mental health impacts of cell phone policies in K-12 schools in the United States. We seek studies that generate actionable insights for policymakers, as well as school and district leaders, who are deciding whether and how to implement or refine such policies. This RFP will support both Randomized Controlled Trials (RCTs) and Quasi-Experimental Designs (QEDs) that can credibly estimate causal effects. While we are open to a range of research questions, we highlight 2 areas of particular interest below.

What are the overall impacts of policies restricting cell phone use in K-12 schools?

• What are the short- and long-term impacts of cell phone policies on student-level outcomes, including academic achievement and attainment (e.g., standardized test scores, graduation rates), behaviors (e.g., engagement, attendance, disciplinary actions), and/or mental health (e.g., depression, anxiety, loneliness)?

• What are the short- and long-term impacts of cell phone policies on school-level outcomes, including school safety (e.g., reported incidents), school climate (e.g., bullying, social connections), and administrative factors (e.g., costs, logistics, communications with parents)?

• Do initial impacts persist, fade, or grow as schools refine their practices over time?

What factors explain variation in the impacts of cell phone policies?

• Which students, schools, and districts are most impacted by cell phone policies?

• Which policy design features (e.g., what devices are banned, when devices are banned, how devices are stored/locked) make cell phone policies more — or less — effective?

• Which implementation strategies (e.g., training and supports for school staff, consistent approaches for enforcement) make cell phone policies more — or less — effective?

• How do the resource and operational implications of different policy approaches (e.g., costs, staff time, infrastructure needs) influence their effectiveness? How do these factors affect the scalability and sustainability of effective approaches?

Armstrong County Community Foundation (The Community Foundation Serving the Heart of Western Pennsylvania)

In 1997 Merchants National Bank, an Armstrong County community bank, marked its 100th anniversary. The centennial celebration included a unique expression of gratitude to the community in the form of $100,000 to be used as a seed fund to initiate a community foundation for Armstrong County. The bank challenged the community to keep the principal balance of the endowed funds intact and spend only a portion of the interest earnings to ensure a lasting legacy.

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Kay Detrick Owen Scholarship

The Kay Detrick Owen Scholarship Fund was established in 2007 by The ARC Manor Foundation to support the education of students who plan to major in, or are currently studying for, a degree in human services.

A human services professional is a generic term for people who hold professional and paraprofessional jobs in diverse settings such as group homes, halfway houses, community mental health centers, programs concerned with drugs and alcohol, domestic violence, aging, correctional programs, programs for people with intellectual disabilities, social workers, and probation/parole officials. Human services is a field of study that assists individuals and communities to function as effectively as possible in major domains of living. Its objective is to meet human needs through an applied knowledge base, focusing on prevention as well as remediation of problems, and maintaining a commitment to improving the overall quality of life of service populations.

Suggested (but not limited to) acceptable examples of college majors and human services positions are psychology, sociology, social work, adult education, individual and family guidance counseling, behavioral management, criminal justice, probation officer, rehabilitation, mental health counselor, marriage and family therapist, substance abuse counselor, grief counselor, case manager, child advocate, child life specialist, etc. 

Bucks County Foundation

Since our founding in 1979, the staff at BCF have been working closely with donors, local leaders, and nonprofit organizations to improve the quality of life in Bucks County. Our work with local charitable organizations helps to improve the health and wellbeing of children and families across the county.

Scholarships

The Bucks County Foundation is proud to support students throughout Bucks County in their pursuit of higher education and attainment of academic, trade and life skills that translate into economic self-sufficiency. Through the generosity of donors in our region, we manage over 100 scholarship distributions for a wide variety of students with diverse educational journeys.

BC Chapter of the American Institute of Architects George J. Donovan Memorial Scholarship

Provides scholarships to students who attend high school in Bucks County and plan to pursue a career in Architecture by pursuing a major such as, but not limited to, Architecture, Architecture Engineering, Civil Engineering, CAD Technology Sustainable Design.

The Baugh Foundation supports progressive, inclusive, nonprofit organizations that reflect the love of Christ by providing assistance to those in need, enriching the lives of children and youth, keeping faith communities informed and engaged, and guarding the wall of separation between church and state.We welcome applications from progressive, faith-based organizations. At this time, the vast majority of our funding goes to progressive Baptist organizations or initiatives, and organizations that work to guard the separation of church and state. We believe that a free church in a free state is dependent upon a functioning democracy.Funding Priorities: 

• Social justice and advocacy
• Progressive faith-based journalism
• Meeting basic human needs
• Progressive faith-based post-secondary education
• Inclusivity initiatives
• Arts and enrichment

This funding opportunity aims to advance mechanistic research for precision probiotic therapies. It invites R33 applications focused on characterizing individual differences in probiotic responses, identifying responder subgroups, and enhancing clinical outcomes. The goal is to develop strategies addressing barriers to effective probiotic use, accounting for human variability. Proposals should include innovative studies using animal models or human subjects, supported by preliminary data to test biological patterns and their effects on health outcomes.

The EDA FY25 Disaster Supplemental program provides critical funding to support communities recovering from severe economic distress caused by natural disasters in 2023 and 2024. With no submission deadlines for Readiness and Implementation Paths, and a specific deadline for Industry Transformation applications, this initiative aims to enhance community resilience and improve economic trajectories through strategic projects that engage local stakeholders and private industries.

The Kretler Scholarship offers up to $1,000 to high school seniors from selected schools in Noble County pursuing degrees in Tool and Die or Mechanical Engineering. This scholarship aims to support students in achieving their educational goals, reflecting the commitment of its donors to invest in local talent. Eligible candidates must maintain a GPA of 3.00 and can reapply in subsequent years, fostering continued academic success in their chosen fields.

The ISF Narrative Film Grant, established by the Islamic Scholarship Fund, supports emerging Muslim filmmakers by providing funding for narrative films in production or post-production stages. With a focus on compelling storytelling and positive portrayals of the Muslim community, the grant offers mentorship and networking opportunities to enhance the filmmakers' projects. Since its inception in 2014, it has awarded $625,000 to over 111 filmmakers, promoting diverse narratives that resonate with audiences.

The Mifflin Memorial Fund Grant supports nonprofit organizations in human services and education, particularly those serving low-income and minority populations. This private fund also contributes to environmental and conservation initiatives, and occasionally cultural organizations for specific projects. Eligible applicants must be tax-exempt nonprofits, ensuring that grants are directed towards impactful community services and educational opportunities.

The Edward M. Nagel Endowed Scholarship, provided by the United Negro College Fund, supports undergraduate students pursuing business-related studies. With a focus on academic excellence and leadership, applicants must maintain a GPA of 3.0 or higher and demonstrate financial need. This scholarship plays a vital role in promoting education for future leaders, reflecting UNCF's mission to empower minority students for over seventy years.

The Celia C. Newcomb Memorial Scholarship, managed by the Crown Point Community Foundation, aims to enrich the lives of South Lake County residents. This scholarship supports Lake County, IN residents pursuing degrees in Education, including high school graduates and adult learners. Applicants must provide an additional essay and meet specific eligibility criteria. It embodies the foundation's mission to address community needs through charitable giving.

The ASPCA Fund to End Factory Farming Grant Program aims to transform the U.S. food system by promoting humane practices and reducing reliance on factory farming. By funding eligible projects, the program seeks to improve animal welfare, support farmers, and enhance public health. Projects must include educational components to raise awareness about their impact. This initiative reflects ASPCA's commitment to ethical treatment of animals and fostering a culture of compassion and inclusion.

The Pittsburgh Foundation provides scholarship opportunities for students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four–year universities, graduate schools, and career/technical schools.

Lightbown Family Scholarship Fund

The Lightbown Family Scholarship Fund was created at The Pittsburgh Foundation to provide scholarships for students from Allegheny County pursuing a career in education. Corinne Elsie Lightbown passed away peacefully on Jan. 7, 2017 at the age of 86 having lived a full and rewarding life. Connie, as she was known to friends, loved life, people, friends and family as well as traveling and discussing movies, political issues and literature. She was an English teacher for 34 years with the Mt. Lebanon High School and taught in London, England, and Japan. A firm believer in the value of a good education, she established this scholarship fund in her name to support students in their academic studies. She never married so had no children of her own, yet her many students became a part of her extended family through the years. Many remained in touch with her and considered her as a mentor and friend. It was her wish that this scholarship would continue beyond her life in this same spirit.

• Award varies
• Award Type: Single Year. Previous recipients are encouraged to re-apply in consecutive years.

The Canada Program Undergraduate Thesis Research Grants, supported by the William Lyon Mackenzie King endowment, provide funding of up to $6,000 for Harvard undergraduates conducting thesis research on Canadian issues. Awardees gain the title of Undergraduate Associates at the Weatherhead Center and are expected to present their findings at a spring conference. The program fosters academic engagement through seminars featuring experts from diverse fields, enhancing the understanding of Canadian societal, cultural, and political dynamics.

The Schilling Scholarship, offered by the Community Foundation of the Ozarks, provides six $3,000 scholarships to graduating high school seniors from select schools. Renewable for up to three years, recipients must maintain a 3.0 GPA, enroll in 12 credit hours, and major in Agriculture. An essay submission is required, and applicants must demonstrate financial need by submitting their FAFSA-SAI. This scholarship aims to support students pursuing degrees in various Agriculture fields.

The ROSES 2025: A.17 Hydrosphere program by NASA aims to enhance our understanding of Earth's water systems, focusing on Ocean Physics, Precipitation Science, and Terrestrial Hydrology. This initiative invites proposals targeting specific priorities within these disciplines to advance knowledge on water distribution and movement across the Earth. Proposals will undergo rigorous peer review to ensure transparency and scientific integrity, aligning with NASA's commitment to reproducible and collaborative research.

The GCA: Catherine H. Beattie Fellowship in Conservation Horticulture, provided by the Garden Club of America, offers an annual research grant of up to $4,500 for graduate students in biology or horticulture. This fellowship aims to promote the conservation of rare and endangered flora in the U.S., particularly focusing on the southeastern region. Eligible applicants must be U.S. citizens or permanent residents enrolled in a U.S.-based institution, with preference given to those studying plants native to the Carolinas.

The Martin Luther King Jr. (MLK) Corridor Community Grants, provided by Keep America Beautiful, aim to empower communities to revitalize and beautify MLK corridors across the U.S. These grants support various projects, including murals, community gardens, and cleanup efforts, contributing to the initiative's goal of beautifying 25,000 communities by 2026. Eligible applicants include nonprofits, local governments, and community organizations, with a focus on sustainable impacts and local engagement.

About The NRA Foundation

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

The NRA Foundation Supports Freedom, Family, and the Future of the Shooting Sports

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans.

The heart of The NRA Foundation’s mission is preserving the core of our American values and traditions in our steadfast effort to Teach Freedom.

Established in 1990, The NRA Foundation, Inc. (“NRA Foundation”) is a 501(c)(3) tax-exempt organization that raises tax-deductible contributions in support of a wide range of firearm-related public interest activities of the National Rifle Association of America and other organizations that defend and foster the Second Amendment rights of all law-abiding Americans. These activities are designed to promote firearms and hunting safety, to enhance marksmanship skills of those participating in the shooting sports, and to educate the general public about firearms in their historic, technological and artistic context. Funds granted by The NRA Foundation benefit a variety of constituencies throughout the United States including children, youth, women, individuals with physical disabilities, gun collectors, law enforcement officers, hunters and competitive shooters.

Awards

The NRA is proud to recognize the contributions of those who have demonstrated dedication to the promotion of the Second Amendment, significantly impacted the preservation of the shooting sports, advanced the purposes and goals of the NRA and exemplified leadership through public service. Each year, women, youth, clubs, law enforcement officers and NRA Foundation volunteers are awarded for their efforts in pursuit of these principles.

NRA Law Enforcement Officer Of The Year Award

NRA's Law Enforcement Officer of the Year Award was established in 1993 and recognizes an exceptional act or service by a law enforcement officer and is administered by the NRA Law Enforcement Division. Nominations are accepted from anyone having knowledge of the nominee's actions. This includes, but is not limited to, the nominee's agency head, other law enforcement officials, elected officials, fellow officers, community leaders, interested citizens, and NRA members.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Lee Shipman Engineering Scholarship

This scholarship has been made possible by the generosity of Lee Shipman who established the Lee Shipman Engineering Scholarship Fund of the Community Foundation for Mason County.

Lee Shipman has always had a love for all things electrical as far back as grade school when he added an additional phone in his family home so calls could be answered from more than one location! This eventually led him to get his degree in electrical engineering and a career at Dow Chemical in Ludington. He continued following his passion after retiring from Dow by working with a local Ludington business helping with the selection and modifications of equipment. Through this work, he recognized the real challenges that downtown merchants face. Lee is thankful for the people who have made a difference in his life, from his Latin teacher to coworkers to close friends and, because of this, he wants to give back to others. He established this Scholarship Fund for students pursuing electrical engineering.

Liberty Bank is committed to enhancing community engagement through its Corporate and Branch Sponsorships, supporting a variety of non-profit organizations and events. With a focus on cultural, educational, and health services, Liberty Bank contributes to initiatives within Connecticut and Greater Springfield, Massachusetts. Sponsorship opportunities include fundraisers, concerts, and sporting events, fostering long-lasting community ties. By investing in local programs, Liberty Bank aims to make a meaningful impact and support the causes that matter most to its communities.