Best Large Grants for Nonprofit Organizations in Massachusetts

The Dr. Anita L. Pinc Memorial Scholarship, administered by the Quad Cities Community Foundation, provides financial assistance up to $1,000 to female students pursuing a medical degree in the U.S. Applicants must be enrolled in a medical school and have ties to Scott County, Iowa, or Rock Island County, Illinois. This renewable scholarship supports students committed to practicing medicine in the Quad Cities region, helping to foster local healthcare professionals.

The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.

The Discovery Boost Grants (DBG) offered by the American Cancer Society support innovative and high-risk exploratory cancer research. These grants, available for up to two years with a funding limit of $125,000 annually plus indirect costs, aim to generate preliminary data that can lead to further funding opportunities. Eligible applicants include independent investigators with a doctorate and a full-time faculty position, fostering advancements in cancer research across multiple priority areas.

The Myelodysplastic Syndromes (MDS) Research Fund Grant, established by the Vera and Joseph Dresner Foundation, aims to enhance research and treatment of MDS and related blood disorders. This fund supports innovative projects addressing etiology, biology, genetics, prognosis, treatment, symptom management, and quality of life. It offers up to $125,000 for Early Career Awards and $250,000 for Established Investigator Awards, facilitating significant advancements in the field.

The Mission Boost Grants (MBG) by the American Cancer Society aim to enhance cancer research by funding projects that translate into human testing. These grants support investigators at all levels, offering resources for innovative clinical projects. The program consists of two funding stages: Stage I focuses on developing clear milestones for new treatments, while Stage II supports patient testing, ultimately contributing to advancements in cancer care and treatment.

The Lozier Foundation

The Lozier Foundation is a private family foundation based in Omaha, Nebraska, funded by Allan and Dianne Lozier. The Foundation supports nonprofit organizations working to expand opportunity, strengthen communities, and improve quality of life for people and families who have historically had less access to resources.

The Foundation’s grantmaking is grounded in a long-term commitment to Omaha and the surrounding region. We are especially interested in work that helps level the playing field, supports people during important moments of need or transition, and gives individuals and families greater ability to make choices about their own lives and futures.

The Foundation’s support has historically focused on established nonprofit organizations working in areas such as education, human services, youth development, health, family stability, and community well-being. While those areas describe much of our grantmaking, they are not intended to serve as fixed categories or a comprehensive list.

The Foundation is selective in its grantmaking. We generally support organizations with a meaningful operating history, capable leadership, sound governance, financial discipline, and a demonstrated ability to serve the community effectively. The Foundation does not typically support early-stage organizations, small projects or organizations with limited reach, or requests that fall outside our geographic and charitable priorities.

The Foundation also considers whether a request reflects a clear understanding of the existing community landscape. We are generally skeptical of efforts that duplicate services already being provided effectively by other organizations, particularly when collaboration, coordination, or partnership would better serve the community. Organizations seeking support should be prepared to explain how their work fits within the broader field, who they collaborate with, and why the proposed work is needed.

Grants

Grantseekers wishing to apply to the Lozier Foundation should begin by reviewing the Mission, Values, Funding Priorities and Funding Eligibility Statements.

The Lozier Foundation grant applications include: Capital Application; Education Application; General Application; and Program Application.

Organizations may receive general operating, program, and capital grants. While The Lozier Foundation prefers to provide ongoing general operating support, organizations can receive a program and/or capital grant in the same calendar year.

Lozier Foundation Program Application

Funding Priorities

• Education
• Women & Girls
• North Omaha Initiatives
• Human Services

The Program Application follows the foundation guidelines provided here.

The Lozier Foundation

The Lozier Foundation is a private family foundation based in Omaha, Nebraska, funded by Allan and Dianne Lozier. The Foundation supports nonprofit organizations working to expand opportunity, strengthen communities, and improve quality of life for people and families who have historically had less access to resources.

The Foundation’s grantmaking is grounded in a long-term commitment to Omaha and the surrounding region. We are especially interested in work that helps level the playing field, supports people during important moments of need or transition, and gives individuals and families greater ability to make choices about their own lives and futures.

The Foundation’s support has historically focused on established nonprofit organizations working in areas such as education, human services, youth development, health, family stability, and community well-being. While those areas describe much of our grantmaking, they are not intended to serve as fixed categories or a comprehensive list.

The Foundation is selective in its grantmaking. We generally support organizations with a meaningful operating history, capable leadership, sound governance, financial discipline, and a demonstrated ability to serve the community effectively. The Foundation does not typically support early-stage organizations, small projects or organizations with limited reach, or requests that fall outside our geographic and charitable priorities.

The Foundation also considers whether a request reflects a clear understanding of the existing community landscape. We are generally skeptical of efforts that duplicate services already being provided effectively by other organizations, particularly when collaboration, coordination, or partnership would better serve the community. Organizations seeking support should be prepared to explain how their work fits within the broader field, who they collaborate with, and why the proposed work is needed.

Grants

Grantseekers wishing to apply to the Lozier Foundation should begin by reviewing the Mission, Values, Funding Priorities and Funding Eligibility Statements.

The Lozier Foundation grant applications include: Capital Application; Education Application; General Application; and Program Application.

Organizations may receive general operating, program, and capital grants. While The Lozier Foundation prefers to provide ongoing general operating support, organizations can receive a program and/or capital grant in the same calendar year.

Lozier Foundation General Application

Funding Priorities

• Education
• Women & Girls
• North Omaha Initiatives
• Human Services

The General Application follows the foundation guidelines provided here.

The Lozier Foundation

Formed in 1986, The Lozier Foundation is a family foundation funded by Allan and Dianne Lozier. The foundation’s focus is education, social services and issues involving women and children with an emphasis on the inner city and underrepresented populations.

Our Mission: The Lozier Foundation’s mission is to improve the quality of life for the underrepresented communities in the Omaha/Metro area.

Grants

Funding Priorities

• Education
• Women & Girls
• North Omaha Initiatives
• Human Services

Grantseekers wishing to apply to the Lozier Foundation should begin by reviewing the Mission, Values, Funding Priorities and Funding Eligibility Statements.

The Lozier Foundation grant applications include: Capital Application; Education Application; General Application; and Program Application.

Organizations may receive general operating, program, and capital grants. While The Lozier Foundation prefers to provide ongoing general operating support, organizations can receive a program and/or capital grant in the same calendar year.

Lozier Foundation Education Application

The Education Application follows the foundation guidelines provided here.

The Gladys W. Cole Memorial Research Award, established by the Geological Society of America (GSA), supports research in geomorphology of semiarid and arid terrains in the U.S. and Mexico. Aimed at GSA Members or Fellows aged 30 to 65, it recognizes significant contributions to the field. Candidates can reapply if additional funding is needed. Notably, funds cannot be allocated for completed work. This award honors Dr. W. Storrs Cole's legacy and contributions to geosciences.

The Crop Science Graduate Student Scholarship, supported by the Gerald O. Mott family, offers financial assistance to outstanding graduate students pursuing M.S. or Ph.D. degrees in crop science. Candidates must demonstrate leadership potential and be enrolled in U.S. institutions, while also being members of CSSA or ASA. Self-nominations are allowed, but former recipients and members of the CSSA Awards Committee are ineligible. This scholarship aims to promote excellence in agronomic education.

The Clyde R. Alleman Memorial Scholarship, offered by the Community Foundation of the Ozarks, provides a $575 scholarship for postgraduate students from Greene County, MO. Applicants must demonstrate financial need and submit a FAFSA-SAI. Preference is given to those pursuing a Medical degree. This scholarship aims to enhance educational opportunities and support students committed to their academic and professional goals.

The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.

About the Foundation

Kern Community Foundation is a vibrant nonprofit enterprise with a powerfully simple mission of growing community and growing philanthropy.

Scholarships

Kern Community Foundation manages more than two dozen scholarship funds. Community stakeholders have created these scholarships to honor their loved ones, to support higher education, and to foster the improvement of students as they pursue their diverse ambitions. Students have access to all our scholarship resources through one simple application.

The Caratan Family Scholarship Fund

The Caratan Family Scholarship Fund was established in 2018. The permanently endowed scholarship fund provides academic support to graduates of Kern County high schools who wish to study STEM (Science, Technology, Engineering, or Mathematics).

KKR Event Sponsorships supports collaborations and programs that address current needs while fostering future growth. The Corporate Citizenship program emphasizes philanthropy, employee engagement, and sustainable community initiatives. Through KKR Cares, employees contribute their skills and time to benefit communities globally. The program focuses on economic opportunity and security, aiding small businesses, social enterprises, and underserved communities through grants, ultimately driving positive outcomes and resilience.

About the Foundation

Kern Community Foundation is a vibrant nonprofit enterprise with a powerfully simple mission of growing community and growing philanthropy.

Scholarships

Kern Community Foundation manages more than two dozen scholarship funds. Community stakeholders have created these scholarships to honor their loved ones, to support higher education, and to foster the improvement of students as they pursue their diverse ambitions. Students have access to all our scholarship resources through one simple application.

David Moore Agricultural Scholarship Fund

Established in 2005, the David Moore Agricultural Scholarship Fund (“Fund”), in memory of David Moore, is a permanently endowed scholarship fund. The Fund provides academic support to graduates of Kern County high schools who wish to pursue a career in agriculture. 

The Fund provides financial assistance to students who are U.S. citizens, and graduates of a Kern County high school who demonstrate motivation, perseverance, and a sincere desire to pursue a bachelor’s degree from an accredited college or university, and who wish to pursue a career in agriculture. Students are required to have a minimum cumulative grade point average of 3.0 at the time of application

The American Cancer Society's Mentored Research Grants for Postdoctoral Fellowships (PF) aim to support emerging researchers in their training programs, fostering their transition to independent cancer research careers. Eligible candidates include US citizens or non-citizens with valid visas who have completed their doctoral degrees within the last four years. The fellowship offers funding for up to three years, with stipends of $66,000 to $70,000 annually, alongside allowances for health insurance and professional development.

The NFL Foundation Grassroots Program, in partnership with the Local Initiatives Support Corporation (LISC), aims to enhance the quality, safety, and accessibility of community football fields. With grants up to $250,000, this initiative addresses the critical lack of safe recreation spaces in low-income neighborhoods, ensuring children and adults have access to well-maintained facilities for gathering and exercise, ultimately fostering community health and well-being.

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Excellence in Medicine Awards- Dr. Jacqueline A. Bello Friend of the AMA Foundation Award

Honors volunteers, AMA staff and donors for their active engagement and unwavering support of the AMA Foundation. Recipients are those who inspire hopefulness and encourage others to join them in giving their time and personal resources to further advance the Foundation’s mission.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Beatrice Prior Memorial Scholarship

The Beatrice Prior Memorial Scholarship Fund awards scholarships to the academically highest ranking graduating female students of Marion Harding High School.

This fund was created from the Mary Evelyn Prior Trust. Mary Evelyn (1924-2008) was a Marion resident. The fund honors her aunt, Beatrice, who was a 1905 graduate of Marion High School (which pre-dates Harding High School) and taught in Lakewood, Ohio, as well as the Marion City Schools’ elementary grades for many years.

The Helen M. McLoraine Foster Care and Emancipated Youth Scholarship provides financial support for youth from the foster care system in Colorado. With a minimum award of $1,000, the scholarship is aimed at those pursuing post-secondary education, including trade schools and universities. Recipients are selected based on academic performance, resilience, and financial need, ensuring that deserving individuals receive the assistance they need to succeed in their educational goals.

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Spenser Flowers Memorial Scholarship Fund

The Spenser Flowers Memorial Scholarship Fund was established at The Pittsburgh Foundation to provide scholarships for traditional and non-traditional students to assist with expenses for college, university or trade school to any youth member or youth who participates in church senior high youth activities (or has participated within the past 7 years) of St. Paul’s United Methodist Church in Allison Park, Pennsylvania.

Award Type: Single-Year Award

The Americana Foundation's American Heritage Grant aims to support projects that broaden inclusivity in early American art and narratives, especially for underrepresented groups. Recognizing the historical significance of Americana, the foundation prioritizes initiatives that promote understanding and appreciation of America's diverse heritage. Eligible applicants include nonprofit organizations and municipal entities. The foundation encourages innovative projects that reinterpret early American material culture, fostering a deeper connection to the past for future generations.

The Pre-College Education Grant from the United States-Japan Foundation aims to foster mutual understanding between young Americans and Japanese through innovative educational projects. The Foundation supports K-12 initiatives that enhance teacher training, develop curriculum materials, and promote Japanese language instruction. With a focus on engaging underserved regions and utilizing technology, this grant encourages collaborative efforts to build networks among educators and students, ensuring a rich exchange of cultural knowledge and experiences.

The Richard Newcomb and Janice Schreiber-Newcomb Scholarship, established by Effie Schreiber in memory of her children, supports students in the Shawano area pursuing higher education. Full-time students can receive $1,000, while part-time students are eligible for $500. This non-renewable scholarship encourages annual applications as long as students maintain enrollment at accredited institutions. The scholarship honors the legacy of Richard and Janice, who were community-oriented and dedicated to education.

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Jack B. McConnell, MD, Award for Excellence in Volunteerism

Honors senior physicians (55+ years old) who are committed to providing medical care to those without access to health care in the U.S.

The McCarthey Dressman Education Foundation offers Teacher Development Grants to support K-12 educators in enhancing their classroom instruction. With grants up to $10,000 per year, individuals or small teams can implement innovative teaching strategies that foster critical inquiry and improve student engagement. This initiative aims to boost educational experiences for diverse learners, encouraging teachers to document and share their methods, ultimately promoting a culture of continuous professional growth.

The 14th Quartermaster/Operation Desert Storm Scholarship Fund, established by The Pittsburgh Foundation, supports Westmoreland County High School students pursuing military careers or whose parents are veterans. Eligible applicants must maintain a minimum GPA of 3.0 and articulate the impact of military service on their family dynamics. This scholarship does not consider financial need, but applicants are encouraged to provide financial information. It aims to foster academic growth and honor military service within the community.