Best Large Grants for Nonprofit Organizations in Massachusetts

The Clifford and Rubye Angleton Scholarship Fund, managed by the Central Kansas Community Foundation, supports graduating high school seniors and college students from Butler County, Kansas, pursuing higher education. Scholarships are based on available funds and applicants' merit. Recipients may renew their scholarships for up to three years with satisfactory academic progress. This initiative emphasizes the importance of rural philanthropy and aims to empower local students to achieve their educational goals.

The Colin and Sally Rowell Memorial Scholarship Fund, managed by the Central Kansas Community Foundation, offers financial assistance to graduating seniors from Butler County, KS high schools pursuing higher education or vocational training. This scholarship aims to support students with a demonstrated interest in education or agriculture, emphasizing financial need and potential for success in college. It reflects the foundation's mission to strengthen communities through charitable giving, promoting rural philanthropy in the central Kansas region.

The Rod's Tire and Service Scholarship Fund, managed by the Central Kansas Community Foundation, offers $2,500 to assist graduating Marion County high school seniors pursuing higher education or vocational training. The foundation, established in 1994, focuses on enhancing community welfare through charitable giving and emphasizes support for students majoring in agricultural fields. This scholarship aims to empower local youth and strengthen the community by investing in their educational futures.

Cures Within Reach

Cures Within Reach is the philanthropic leader in drug, device and nutraceutical repurposing research, which has the potential to transform the lives of patients with unsolved diseases by delivering treatments that can be used in the near-term. Our focus: we find and fund proof-of-concept clinical trials that, once successful, de-risk and catalyze follow-on funding, building the clinical evidence required for regulatory approval or to support off-label use by patients everywhere.

Clinical Repurposing Research to Impact US Veterans/Military

This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking clinical repurposing trials from US-based research institutions using already approved treatments to address unmet and high-priority medical needs of US veterans and/or active US military, such as mental health, post-traumatic stress disorder (PTSD) and brain injuries. Our strongest preference is for proof of concept, pivotal, Phase I or Phase IIA clinical repurposing trials. Eligible trials may be conducted at accredited US-based academic, nonprofit and governmental research institutions and/or health systems involved with medical research, including Veterans Administration (VA) health systems and hospitals. 

Repurposed therapies must be approved and/or generally recognized as safe for human use by some regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health Canada or Japan’s Pharmaceuticals and Medical Devices Agency, and may include drugs, devices, nutraceuticals or diagnostics, as well as combination therapies. These repurposed therapies must be tested in a new indication for which they are not already approved or used widely in clinical practice as standard of care. Repurposed therapies also may be added to current standard of care to improve patient outcomes and/or quality of life.

The BioMarin Medical Education Grant offers funding for educational activities aimed at enhancing the knowledge and skills of healthcare professionals. Eligible applicants include accredited providers, medical associations, and patient advocacy groups. The grant focuses on supporting initiatives related to rare diseases, ensuring timely access to treatments and education. Applications are accepted year-round, but a minimum of 60 days is required for review prior to events. This commitment underscores BioMarin's dedication to improving patient care and advancing medical knowledge.

The Vela Foundation Grant supports nonprofit organizations focused on improving nutrition and wellness in underserved communities, particularly those with annual budgets under $5 million. Preference is given to organizations operating in low-income areas and those with budgets under $3 million. The foundation aims to enhance access to healthy foods and provide nutrition education in the Greater Boston area and Gateway Cities, fostering entrepreneurial programs that promote community wellness.

The EMF EMRA Resident Research Grant, funded by the Society for Academic Emergency Medicine Foundation, aims to enhance research in emergency medicine by providing up to $10,000 for residents in accredited programs. This grant promotes the development of future researchers, improves patient care, and supports effective health policy through rigorous scientific inquiry. Eligible applicants must be ACGME-approved residents and secure a faculty preceptor's support, ensuring a robust educational experience in research methodologies.

 Cherokee Nation Nursing and Allied Health Scholarship

The Cherokee Nation Nursing and Allied Health Scholarship is to provide financial assistance to Cherokee Nation citizens pursuing college degrees in nursing and health care fields to support their readiness to contribute to and grow within the Cherokee Nation reservation labor market. 

About Levitt

The Levitt Family Foundation exists to strengthen the social fabric of America. We partner with communities to activate underused outdoor spaces, creating welcoming, inclusive destinations where the power of free, live music brings people together and invigorates community life.

Festival Grants

The Levitt Foundation is offering grants of up to $5,000 to U.S.-based 501(c)(3) nonprofits presenting free outdoor music festivals in 2026. 

The Brennan Family Foundation, established in 1990 by Edward J. Brennan, aims to support charitable, educational, and religious institutions. With a mission to inspire youth development, the foundation provides financial assistance primarily to health care and educational organizations, religious entities, and the arts. Their strategic annual review process ensures that contributions effectively serve our most valuable resource—children. The foundation continues to honor Brennan's legacy of charitable responsibility.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Peter V. Westhaysen Medical Education Scholarship

Scholarships are available for post-secondary undergraduate, graduate and post-graduate students pursuing a degree to become a physician or nurse at an accredited university. The purpose of the scholarship is to assist the student with the costs of tuition, fees, and books. The Advisory Committee consider two basic criteria: academic achievement and financial need.

Napa Valley Community Foundation

There are more than 800 Community Foundations in the US, each devoted to a specific region. We operate independently, with a common goal in mind: to be a platform for local people who want to pay it forward. To deliver resources to effective charitable programs. And to make our communities stronger and more successful by doing these two things.

Among our peers, Napa Valley Community Foundation ranks first on several key measures of donor satisfaction and impact, according to a recent donor survey conducted by the Center for Effective Philanthropy. Our donors say that we deeply understand their interests, and deeply understand the needs of Napa Valley. That, in a nutshell, is our job.

Ted Kohler Music Scholarship

The Ted Kohler Music Scholarship benefits Calistoga students who are committed to music and wish to advance their musical development. The scholarship can be used to pay for activities such as music lessons or summer camp, or for college tuition (where the student demonstrates their desire to continue their musical education). The Ted Kohler Scholarship was established in 1997 to promote musical participation and aspirations in honor of Ted, who upon retirement from San Francisco State University, became a full-time musician and leader of the Napa Valley Jazz Band. He encouraged people of all ages to express themselves musically.

The Jean T. Grant Scholarship, established by The Columbus Foundation, honors the legacy of Jean Terry Grant, a devoted librarian and arts advocate. Providing $1,000, this scholarship supports graduating seniors from Columbus City Schools pursuing studies in music or the arts. Jean's commitment to education and the arts inspires future generations, ensuring that her passion for creativity and philanthropy continues to impact the community positively.

The Robert L. Johnson Memorial Research Grant, offered by the Midwest Aquatic Plant Management Society, supports graduate students in aquatic plant management with grants of up to $10,000. This initiative promotes research that advances the management of aquatic ecosystems and fosters educational opportunities. Recipients are required to present their findings at the annual conference, contributing to the society's mission of sustainable aquatic resource management and ecological preservation.

Our Mission

The Sundance Institute is a nonprofit organization dedicated to the discovery and development of independent artists and audiences. Through its programs, the Institute seeks to discover, support, and inspire independent film and media artists from the United States and around the world, and to introduce audiences to their new work.

Sally Menke Editing Fellowship

Description of Fellowship

The Sally Menke Editing Fellowship will include the following elements:

• Two editing mentors; collaboration with Sundance Institute staff to identify the mentors who will be available from July 2026 through May 2027. You will engage in monthly meetings with one or both of the mentors for advice on the editing process and potential opportunities for career development. When appropriate, there might be a key moment to observe mentors at work during an essential part of their process.

• Invitation to join the American Cinema Editors as an associate member. Benefits include receiving the ACE CinemaEditor Magazine, invitations to events, and screeners, with the opportunity to vote for the Feature Film Best Editing categories as part of the ACE Awards.

• Invitations to join periodic informal gatherings of the cohort of Menke fellows.

• Invitation to join the Art of Editing event at the 2027 Sundance Film Festival, where the annual Menke fellow is announced.

• Participation as an editor for two of the directing fellows at the 2026 Sundance Directors Lab (fellow must be available to attend in person at the Stanley Hotel in Estes Park, Colorado, anticipated dates June 10–23, 2026).

The Inter American Press Association (IAPA) is inviting media professionals from North America, Latin America, the Caribbean, and Spain to participate in the Awards for Excellence in Journalism. This prestigious competition features 14 categories, including Migration Journalism and Sustainability, to highlight significant contributions in journalism. Open to works published in Spanish, English, or Portuguese, the contest encourages broad participation. Winners will receive awards, with many categories offering prizes of US$2,000.

Mission

To empower worthy nonprofits by providing critically needed, unrestricted funding that helps them fulfill their missions with confidence and sustainability.

How We Serve Nonprofits

AmFund partners with nearly 800 organizations annually—supporting causes related to health, education, the arts, human services, animal welfare, and more. We’re known for our:

• Signature silent and live auctions featuring once-in-a-lifetime travel experiences.
• National reach with personalized service at events in all 50 states.
• Comprehensive marketing toolkits, onsite staff support, and beautifully displayed materials
• No-cost platform development for virtual and hybrid fundraising
• In-house travel specialists who provide custom planning, extensions, insurance, and 24/7 emergency support.
• Ongoing educational resources, grants, and consulting support for nonprofit development.

Request Support

Our model is built on relationship, trust, and results. Every trip sold, every service provided, and every donor interaction is designed to maximize your fundraising impact—without adding burden to your team.

The PERF: CNS Bridge Grant Program aims to support emerging child neurology researchers by providing essential bridge funding while they seek independent research grants from NIH or CIHR. Established by the Pediatric Epilepsy Research Foundation in collaboration with the Child Neurology Society, this initiative seeks to retain talented investigators in the field of pediatric neurology. Since its inception, the foundation has awarded over $18 million to advance pediatric epilepsy research and related conditions.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Barbara Miller Meeker Art Scholarship

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

About

Created by the community for the good of the community, the GLCCF is here to turn problems into opportunities through strategic grant making and initiatives created to address our region’s most pressing needs. We work with you to identify your charitable goals, and we ensure that they are carried out efficiently.

Work with us to make the kind of impact you want to see in your community. Let us take on the financial complexities and paperwork, while you focus on the important things like fostering good works throughout our community.

When you give to the Greater Lake City Community Foundation, you are making an investment that will benefit the community, now and in the future.

GLLCF Nursing Scholarship

To award annually a scholarship to a qualified applicant who intends to further his/her education toward a degree in nursing.

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Robert J. O’Connor Memorial Scholarship Fund

The Robert J. O’Connor Memorial Scholarship Fund was created as a way to honor his long-standing relationship with the Community Foundation and the passion he held for helping local students pursue their educational goals. Bob’s connection to the Community Foundation started when he was the recipient of a scholarship as a 1962 graduate of East Aurora High School. He would later serve nine years as a Foundation Board member.

Native Voices Rising (NVR) offers grants to empower Native-led grassroots organizations in the U.S. With over $16 million awarded since inception, NVR focuses on enhancing lives through collective action and advocacy. Eligible organizations must be Native-led and engage community members in policy improvement efforts. NVR supports initiatives addressing environmental justice, health, and youth involvement, with a commitment to fostering leadership and social change within Native communities.

The US Acute Care Solutions Scholarship Fund, established by Stark Community Foundation, supports the dependent children of non-physician employees of US Acute Care Solutions and its affiliates. Eligible applicants must be accepted into or attending a college, university, nursing school, or vocational program, with a minimum GPA of 3.0. This initiative highlights the Foundation's commitment to empowering future generations through education and community service involvement.

The Ruth M. Cogan Foundation Trust Fund, established by the Stark Community Foundation, supports students from Stark County, Ohio pursuing college education in music. This fund aims to help graduating seniors or current college students who demonstrate a passion for music and embody the spiritual qualities exemplified by Ruth. Since 1963, the Foundation has evolved from a grantmaker to a community leader, transforming lives through philanthropy.

The Rotary Works Foundation Grant supports charitable projects primarily focused on children, youth, and families, emphasizing active Rotarian involvement. Grants range from $500 to $5,000, awarded prior to events. Eligible applicants include 501(c)(3) or 501(c)(1) organizations. Preference is given to projects engaging Rotarians. The application deadline is the 2nd Wednesday of each month, and all grantees must report outcomes post-project.

The Jennie K. Scaife Charitable Foundation Grant focuses on enhancing family support, women's and children's health, and animal welfare. It aims to fund programs that promote beneficial human-animal interactions and early intervention in addiction prevention. Eligible organizations must have a valid 501(c)(3) designation. Grants align with at least one of the foundation's focus areas, ensuring impactful contributions to community welfare and well-being.

The O'Jays Scholarship Fund, established by the Stark Community Foundation, supports Stark County seniors graduating high school or residents with a GED pursuing higher education. Eligible applicants must maintain a minimum GPA of 2.5 and demonstrate financial need. This initiative reflects the Foundation's long-standing commitment to enhancing educational opportunities and addressing community challenges since its inception in 1963. The program aims to empower students to achieve their academic goals and improve their futures.