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Best McCook County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in McCook County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

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$3.26B

Total funding

$5K

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9,000+ grants
$3.26B total
$5K median

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8,985 Results based on applied filters

The Canton Advertising Federation Endowment for Creative Enrichment Fund

Stark Community Foundation
Private
United States
More than US $500

Stark Community FoundationStark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.The Canton Advertising Federation Endowment for Creative Enrichment FundThe Canton Advertising Federation Endowment for Creative Enrichment Fund assists graduating high school seniors or current college students majoring in advertising, graphic design, communication or related fields. Applicants must reside in Stark County.Renewable Scholarship: Yes

Education - Higher Education Career / College Preparation

The Adrienne O'Neill Scholarship Fund

Stark Community Foundation
Private
United States
More than US $500

Stark Community FoundationStark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.Adrienne O’Neill Scholarship FundThe Adrienne O’Neill Scholarship Fund was established to assist students who are the first generation in their family to attend college. Applicant must have a cumulative GPA of 2.5, demonstrate financial need and intend to utilize this scholarship as the “last dollars” after all aid/scholarships have been awarded.Renewable Scholarship: Yes

Education - Higher Education College Success / Persistence

Giving Circle for the Advancement of Women (GCAW) Award

The Society of Interventional Radiology Foundation
Association/Society
Canada, United States
Unspecified amount

The Society of Interventional Radiology Foundation

SIR Foundation is a scientific foundation dedicated to fostering research in interventional radiology for the purposes of advancing scientific knowledge, increasing the number of skilled investigators, and developing innovative therapies that lead to improved patient care and quality of life. The foundation is committed to fostering the development and enhancement of innovative, minimally invasive, image-guided therapies from inception to mature clinical application and to conduct educational programs in the service of its mission.

Giving Circle for the Advancement of Women (GCAW) Award

Provide career development opportunities for women in interventional radiology. GCAW is dedicated to engaging all generations of women in interventional radiology through the power of community philanthropy.

Health & Medicine Biomedical Imaging

The Virginia C. Jack and Ralph L. Jack Scholarship Fund

Stark Community Foundation
Private
United States
More than US $500

Our Story

Since 1963 when Stark Community Foundation was formed, hundreds of thousands of people’s lives have been changed through the power of philanthropy.

Over the years, the role of the Foundation has grown from a simple grantmaker to a community leader seeking long-term solutions to diverse community challenges.

The Virginia C. Jack and Ralph L. Jack Scholarship Fund

The Virginia C. Jack and Ralph L. Jack Scholarship Fund was established to assist students who are residents of Stark County; admitted to technical school, college or university, or school of nursing (full or part-time); traditional or non-traditional students accepted. Applicants must have attained a GPA of at least 3.5 on a 4.0 scale and demonstrate financial need.

Education - Higher Education Academic Scholarship Programs Nursing +1 more

Health Promotion and Disease Prevention Research Centers: 2027 Special Interest Project Supplements (SIPS)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The Health Promotion and Disease Prevention Research Centers are offering supplemental funding for Special Interest Projects (SIPs) aimed at enhancing public health practices. These projects will focus on innovative health promotion and disease prevention strategies to mitigate leading health risks in the U.S. The initiative supports ten specific SIPs, including studies on cancer care, alcohol use reduction, and emergency preparedness, thereby fostering research that translates into real-world health improvements.
Cancer / Oncology

Expanded Surveillance for Pediatric Infectious Diseases

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $850,000 - US $1,140,000
This funding opportunity aims to establish a U.S. network for active surveillance of pediatric acute respiratory illnesses and gastroenteritis. The initiative will focus on respiratory and enteric viruses, assessing the effectiveness of prevention products such as vaccines. Recipients will follow CDC protocols to enroll patients and confirm viral infections, ultimately reducing hospitalizations and enhancing public health strategies for children's healthcare.
Infectious & Parasitic Diseases Children’s Health & Pediatrics

Improving Protection against Influenza and Other Respiratory Pathogens: the US Flu VE Network

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $1,350,000 - US $3,550,000
The US Flu Vaccine Effectiveness (VE) Network aims to enhance the effectiveness of vaccines against influenza and other respiratory pathogens, which are significant contributors to morbidity and mortality. This funding opportunity invites proposals for surveillance studies, including annual VE assessments, acute respiratory illness tracking, household transmission research, and immunogenicity studies. Applicants can apply for either Component A or B, with the option to include additional components based on their primary selection.
Respiratory Diseases & Systems

INCLUDE Project: Omics Phenotypes Related to Down Syndrome (X01 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The INCLUDE Project aims to enhance the health and quality of life for individuals with Down syndrome by generating comprehensive genomic and multi-omics data. This initiative encourages applicants to submit samples to NIH-supported resources, facilitating the exploration of molecular mechanisms related to health conditions associated with Down syndrome. The data will be shared via the INCLUDE Data Hub, promoting collaboration within the research community, though no direct funding is available to applicants.
Down Syndrome

Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The National Cancer Institute (NCI) is set to release a Notice of Funding Opportunity (NOFO) aimed at advancing informatics technologies for cancer research. This initiative will support the development of tools that enhance data acquisition, management, and analysis throughout the cancer continuum. By focusing on technologies with proven impact, the NOFO seeks to optimize and sustain resources critical for cancer biology, diagnosis, treatment, and epidemiology.
Cancer / Oncology Biomedical informatics

National Digital Newspaper Program (364030)

National Endowment for the Humanities
Federal Government
American Samoa, Guam +4 more
Up to US $325,000
The National Digital Newspaper Program (NDNP) invites applications to digitize historically significant newspapers published between 1690 and 1963 across the U.S. This initiative by the National Endowment for the Humanities and the Library of Congress aims to create a comprehensive online database accessible to the public. Successful applicants will convert approximately 100,000 pages into digital format over two years, following specific technical guidelines. This program enhances access to vital historical resources for research and education.
Humanities & Social Science Community Culture & Heritage Library & Information Science +2 more

Social Impact Partnerships to Pay for Results Act Demonstration Projects

U.S. Department of the Treasury
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Social Impact Partnerships to Pay for Results Act (SIPPRA) by the U.S. Department of the Treasury aims to enhance social service effectiveness through innovative funding strategies. Established in 2018, SIPPRA encourages state and local governments to apply for awards that redirect funds from ineffective programs to those that yield measurable outcomes. By promoting public-private partnerships and performance-based funding, SIPPRA seeks to address critical social issues and improve the lives of families and individuals in need.
Poverty Alleviation & Services Human & Social Services Community Development & Revitalization

Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), Research Program (U19 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is launching a funding opportunity for the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD). This program aims to foster multidisciplinary research on FASD, addressing critical needs such as early identification, intervention development, and mechanisms of alcohol exposure effects. By supporting integrated projects within the CIFASD consortium, the initiative seeks to enhance understanding and reduce the impact of FASD through coordinated research efforts.
Neurological Diseases & Disorders Addiction & Substance Use Disorders Preventative Healthcare

Community Development Block Grant Program for Indian Tribes and Alaska Native Villages (364031)

US HUD: Office of Public and Indian Housing (PIH)
Federal Government
United States
US $500,000 - US $2,250,000
The Community Development Block Grant Program for Indian Tribes and Alaska Native Villages aims to foster the development of viable communities by providing funding for housing, living environments, and economic opportunities, primarily benefiting low- and moderate-income individuals. The program is competitive, offering both single-purpose and imminent threat grants to address urgent public health and safety issues, ensuring that tribes can improve their community welfare effectively.
Economic Services & Development Community Development & Revitalization Community / Public Safety +2 more

Centers for Research on Neglected Infectious Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is launching the Centers for Research on Neglected Infectious Diseases (CReNIDs) to enhance research on neglected infectious diseases (NIDs). This initiative aims to tackle substantial health challenges posed by communicable viral, bacterial, and parasitic infections, especially in endemic regions. By fostering multidisciplinary research and sustainable local capacities, the program seeks to improve health outcomes and mitigate the spread of these diseases, ultimately safeguarding public health in the U.S. and globally.
Epidemiology & Public Health Infectious & Parasitic Diseases International / Foreign Affairs

Community Engaged Research Grant (NBCOT®)

The American Occupational Therapy Foundation Inc
Private
United States
Up to US $100,000

About AOTF

Established in 1965, AOTF is an independent 501(c)(3) charitable, scientific, and educational organization. We serve as the premier resource for occupational therapy research and scholarship, working alongside researchers, educators, practitioners, community partners, and students to build evidence-based practice that improves lives.

As the only foundation dedicated exclusively to advancing occupational therapy science, we bridge the critical gap between innovative research and real-world practice. Our work ensures that occupational therapy interventions are grounded in rigorous scientific evidence, ultimately improving outcomes for millions of people worldwide.

Community Engaged Research Grant (NBCOT®)

Background

It is imperative that occupational therapy research is grounded in the priorities and lived experiences of the individuals it aims to serve, particularly for historically marginalized or underrepresented communities.

Community-engaged research is a collaborative approach that establishes equitable and meaningful partnerships between researchers, community members, service providers, and other stakeholders throughout all phases of the research process. It centers on addressing community-identified priorities and co-creation of research that produces mutually beneficial outcomes.

By ensuring that research is culturally relevant, contextually appropriate, and responsive to community priorities, this approach enhances its impact while improving health, participation, and quality of life.

Program Mission

The Community Engaged Research Grant program supports studies that apply rigorous qualitative and/or quantitative methodologies to address research priorities and service or knowledge gaps identified in partnership with communities.

AOTF emphasizes the importance of equitable partnerships in which power, decision-making, and responsibility are shared between researchers, practitioners, community-based organizations, people with lived experience, and other relevant partners.

By fostering these inclusive practices, AOTF aims to ensure that occupational therapy scholarship remains scientifically rigorous, equitable, and responsive to the real-world needs of diverse communities.

Funding Priorities

All proposed projects must: 

  • Be led by a community-academic partnership.
  • Identify at least one community member as a Co-Investigator.
  • Demonstrate meaningful and equitable engagement of community partners.
  • Include a plan to compensate community partners.
  • Address potential barriers to engagement
  • Clearly align with the scope of occupational therapy practice.
  • Focus on original research.
Occupational Therapy

AOTF President’s Award

The American Occupational Therapy Foundation Inc
Private
United States
Unspecified amount

About AOTF

Established in 1965, AOTF is an independent 501(c)(3) charitable, scientific, and educational organization. We serve as the premier resource for occupational therapy research and scholarship, working alongside researchers, educators, practitioners, community partners, and students to build evidence-based practice that improves lives.

As the only foundation dedicated exclusively to advancing occupational therapy science, we bridge the critical gap between innovative research and real-world practice. Our work ensures that occupational therapy interventions are grounded in rigorous scientific evidence, ultimately improving outcomes for millions of people worldwide.

AOTF President’s Award

The President’s Award honors and recognizes Pi Theta Epsilon chapters that organize and implement outstanding scholarly activities. This award celebrates chapters whose events increase knowledge, develop professional skills, and help advance the occupational therapy profession.

Review Process: Applications are accepted on a rolling basis with an annual review beginning January 31. The national PTE Executive Board evaluates all submissions.

Multiple Awards: When appropriate, a second award may be considered to distinguish outstanding individual and interchapter accomplishments.

Occupational Therapy

PTE Grant for Excellence in Interchapter Collaboration

The American Occupational Therapy Foundation Inc
Private
United States
Unspecified amount

About AOTF

Established in 1965, AOTF is an independent 501(c)(3) charitable, scientific, and educational organization. We serve as the premier resource for occupational therapy research and scholarship, working alongside researchers, educators, practitioners, community partners, and students to build evidence-based practice that improves lives.

As the only foundation dedicated exclusively to advancing occupational therapy science, we bridge the critical gap between innovative research and real-world practice. Our work ensures that occupational therapy interventions are grounded in rigorous scientific evidence, ultimately improving outcomes for millions of people worldwide.

PTE Grant for Excellence in Interchapter Collaboration

The PTE Grant for Excellence in Interchapter Collaboration honors and recognizes Pi Theta Epsilon chapters that excel in creating meaningful partnerships with other chapters. This award celebrates collaborative efforts that support PTE’s mission and expand the impact of scholarly activities across multiple institutions.

This grant recognizes interchapter collaborations that:

  • Support and advance the Pi Theta Epsilon mission
  • Increase knowledge in occupational therapy
  • Develop professional skills among members
  • Contribute to the advancement of the OT profession
  • Foster connections between chapters and institutions

Collaboration Definition: Activities organized and implemented by two or more Pi Theta Epsilon chapters working together toward a common scholarly goal.

Examples of Qualifying Collaborations:

  • Joint events or conferences
  • Collaborative workshops
  • Co-authored educational or scholarly papers
  • Virtual symposiums
  • Multi-chapter research initiatives
  • Regional or national networking events
Occupational Therapy

BJA FY 2026 Justice Reinvestment Initiative: Strengthening State and Local Operations to Reduce Crime and Recidivism

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $4,000,000
The BJA FY 2026 Justice Reinvestment Initiative aims to enhance state and local operations to effectively reduce crime and recidivism. This funding opportunity encourages state, local, and tribal governments to optimize resource allocation within the justice system, targeting urgent challenges through data-driven project proposals. By addressing areas such as law enforcement, prosecution, and probation, applicants can focus on strategies that maximize public safety and reduce the inefficient use of funds.
Crime & Justice Community / Public Safety

Genesis Mission Graduate Fellowship Pilot

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
US $12,000,000 - US $25,000,000
The Genesis Mission Graduate Fellowship Pilot aims to empower American scientists and engineers in the super intelligence (SI) revolution by inviting applications from U.S. higher education institutions. This initiative focuses on developing innovative doctoral training programs integrating SI with other scientific disciplines. Participants will gain valuable research experience through collaborations with DOE National Laboratories and industry, preparing them as the next generation of skilled Ph.D. scientists and engineers to tackle pressing national science and technology challenges.
Education - Higher Education Workforce Preparation & Job Readiness Emerging Technology Development +2 more

ROSES 2025: B.7 The Heliophysics Low-Cost Access to Space

National Aeronautics and Space Administration (NASA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Heliophysics Low-Cost Access to Space (H-LCAS) program, under NASA, aims to foster innovative technologies and instruments for flight investigations utilizing sounding rockets, high-altitude balloons, and CubeSats. By advancing Heliophysics science, H-LCAS provides critical pathways for technology maturation and suborbital demonstrations. Proposals should align with the National Research Council's Decadal Strategy for Solar and Space Physics, emphasizing societal applications and supporting human exploration initiatives.
Physics Astronomy & Astrophysics Aerospace Engineering +2 more

OJJDP FY 2026 Emergency Planning for Juvenile Justice Residential Facilities

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The OJJDP FY 2026 Emergency Planning for Juvenile Justice Residential Facilities program aims to enhance emergency preparedness in juvenile justice facilities across the country. This funding opportunity supports the development and implementation of comprehensive emergency plans that prioritize the safety of youth and staff, ensure effective communication with families, and maintain operational continuity during crises. By empowering facilities to improve their response and recovery capabilities, the program seeks to mitigate risks associated with emergencies, whether natural or man-made.
Youth Services Crime & Justice Community / Public Safety +1 more

Operation Grant

Petfinder Foundation
Private
United States
Unspecified amount

About Us

We help shelters and rescue groups save pets.

Saving pets. Together.

The Petfinder Foundation has been helping animal shelters and rescue groups since 2003. We are the ONLY national organization that does nothing but give cash and product grants to adoption groups.

Operation Grant

Grants vary depending on the organization’s need to support the number of adoptable pets listed on Petfinder and are awarded on a monthly basis throughout the year until all funds are depleted.

Animal Welfare - Domestic Animals & Pets

Single Ventricle Research Fund (SVRF) - Career Development Track

Additional Ventures Foundation
Private
Countries
Up to US $300,000

Single Ventricle Research Fund (SVRF)

Our flagship funding program — the Single Ventricle Research Fund (SVRF) — is an annual research award program that supports foundational studies aimed at improving outcomes for individuals with single ventricle heart disease. By addressing the organ- and multi-organ-level complications and clinical sequelae that drive long-term morbidity and mortality, the SVRF seeks to close critical gaps in understanding and treatment, and accelerate progress toward better, more predictive, and preventative care.

In its sixth cycle, the SVRF welcomes foundational research that is directly relevant to improving outcomes for individuals with single ventricle heart disease.

What Fits

Through the SVRF, Additional Ventures aims to accelerate foundational research that will lead to improved care and new therapeutic opportunities grounded in a mechanistic understanding of single ventricle heart disease.

The 2027 SVRF welcomes research aligned with the focus areas and strategic topics described in the Additional Ventures’ 2026 Research Roadmap. We are particularly interested in proposals that seek to elucidate the mechanisms underlying, prevent, or reverse the interrelated organ- and multi-organ-level sequelae that contribute to long-term morbidity and mortality.

Eligible investigators include postdoctoral fellows or equivalents holding a mentored position. Collaborative proposals will not be accepted through this track.

Cardiovascular Diseases & Systems Heart Disease Preventative Healthcare

ROSES 2025: B.8 Heliophysics Spaceflight Science Foundations

National Aeronautics and Space Administration (NASA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The ROSES 2025 program is focused on enhancing the scientific and technical readiness of key Decadal Survey investigations in heliophysics, specifically 'Links' and 'Solar Polar'. It aims to support research that aligns with the 2024 Heliophysics Decadal Survey's goals by identifying completable science objectives. Proposals should include innovative mission architecture and science objectives, while leveraging existing capabilities of heliophysics missions, without soliciting specifications for observations or instrumentation.
Physics Astronomy & Astrophysics Aerospace Engineering +1 more

OJJDP FY 2026 Juvenile Justice System Enhancements

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $1,324,666
The OJJDP FY 2026 Juvenile Justice System Enhancements program aims to bolster the effectiveness of juvenile justice systems across the nation. By targeting high-cost drivers of crime and enhancing youth outcomes, this initiative encourages states and localities to develop strategic solutions. Applicants are invited to identify challenges within their systems and prioritize resource allocation for measurable improvements, ultimately aiming to prevent crime and improve operations within the juvenile justice framework.
Youth Services Crime & Justice Community / Public Safety

PLTW Engineering - New Program (Lockheed Martin)

Project Lead the Way inc.
Private
United States
US $10,000

About PLTW EngineeringPLTW Engineering students adopt a problem-solving mindset, are engaged in compelling, real-world challenges that help them become better collaborators and thinkers, and are prepared with skills to step into any career path they take. Lockheed Martin has committed funds to support PLTW grants to schools interested in adding PLTW.Since 2007, Lockheed Martin has partnered with PLTW to address the nation's critical need for future engineers, computer scientists, and math- and science-trained professionals, and to equip all students with the knowledge and skills they need to thrive. Lockheed Martin supports PLTW programs in school districts across the nation and has contributed to the development of PLTW's middle school and high school courses focused on aerospace engineering and flight. Since the first school district partnership in 2014, over 855 PLTW programs have been implemented and more than 145,328 students have gained access to PLTW.Program Requirements:Grantee must offer at least one PLTW Engineering course in the 2027-2028 academic year. Grantee may implement any PLTW Engineering course of their choosing. Grant Award and Distribution Schedule:

  • Total Award: $10,000
    • 2027-2028: $10,000
Engineering STEM / STEAM Education

McCook County Grants for Nonprofits Highlights

Looking for McCook County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all McCook County grants recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in McCook County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the McCook County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for McCook County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538