Best McCook County Grants for Nonprofits in South Dakota

About Father John Foundation GrantIn 1997 Monsignor John P. Hourihan established this perpetual charitable foundation for the purpose of funding care for the homeless and people with disabilities, especially the deaf and hard of hearing. The purpose of the Foundation is to financially assist churches and other non-profit organizations, that do not take more than insubstantial government funding, in administering their programs. Our giving focus is broad and considers programs that are: religious, educational, rehabilitational, social, and/or vocational. A priority is given to the deaf and homeless. All funding is given regardless of nationality, race or religion. The Foundation will continue its dedication to raising and distributing grants to be used by charities devoted to providing care and services to the homeless and disabled.

American Brain Foundation

The American Brain Foundation funds research across the spectrum of the brain and nervous system, because it is our best hope for improving treatments, advancing prevention strategies, and discovering cures. Brain diseases, disorders, and injuries are interconnected. When we cure one, we will cure many.

Next Generation Research Grants

The American Brain Foundation’s Next Generation Research Grants (NGRGs) support early career investigators conducting high-quality research aimed at better understanding, treating, and curing brain diseases. These grants are offered in collaboration with disease-focused partner organizations and reflect ABF’s Cure One, Cure Many research philosophy: the belief that breakthroughs in one area of research accelerate progress across many others.

Lawrence M. Brass, MD Clinical Research Training Scholarship in Stroke

This award aims to recognize the importance of good clinical research and to encourage early career investigators in clinical studies related to stroke, vascular neurology, and neurocritical care.

For the purpose of this scholarship, research is defined as “patient-oriented research conducted with human participants, or translational research specifically designed to develop treatments or enhance diagnosis of neurological disease. These areas of research include epidemiologic or behavioral studies, clinical trials, studies of disease mechanisms, the development of new technologies, and health services and outcomes research.” Disease-related studies not directly involving humans or human tissue are also encouraged if the primary goal is the development of therapies, diagnostic tests, or other tools to prevent or mitigate neurological diseases.

Agnes McCarthy Caregiver Foundation

The Agnes McCarthy Caregiver Foundation is a 501(c)(3) not-for-profit charity that provides hope and relief to caregivers who care for a loved one with mental health conditions.

Caregiver Grant

Family caregiving has become a public health issue that receives inadequate recognition in our country. While it can be rewarding to care for our loved ones, it often comes with significant physical, emotional and financial costs to the caregiver. On average, caregivers spend over 25% of their own income to support their loved one and provide 32 hours a week in unpaid care.

AMCF currently offers a $500 financial relief grant to assist family members with unexpected expenses due to their caregiving role. If you are a family caregiver to someone living with a mood or psychiatric condition like depression, anxiety, PTSD, bipolar, schizophrenia, or other mental health/co-occurring conditions, you are not alone, and we welcome you to apply for a caregiver grant today.

Additional Information

• To ensure our limited funds reach families with the greatest need, grants may require documentation confirming a diagnosed serious mental illness (SMI).  

• The $500 grant is limited to one award per household within a 12-month period.

• Applications are generally reviewed by our Board of Directors, with decisions made within 30 days of receipt.

T7 Social Impact GrantsThe T.D. Jakes Foundation (TDJF), in partnership with Wells Fargo, is proud to launch the Social Impact Grant Challenge, a transformative funding opportunity designed to identify, support, and amplify nonprofit organizations creating meaningful change in communities across the United States.

Designed around the T.D. Jakes Foundation's pillars of service (Educational Access & Workforce Readiness, financial inclusion, and community transformation and well-being), the Challenge seeks innovative nonprofit organizations that are addressing critical social issues through impactful, scalable, and sustainable solutions.

Finalists selected through this process will have the opportunity to showcase their organization through a live presentation at the inaugural Thriving Seven (T7) Summit, taking place November 12 –14 in Atlanta, Georgia. In addition to competing for grant funding, finalists will gain national visibility for their work and connect with nonprofit leaders, funders, and changemakers from across the country.Grant Funding: A total of $1,500,000 in grant funding is anticipated to be awarded: 

• One (1) - $500,000 grant
• One (1) - $250,000 grant
• Two (2) - $100,000 grant
• Eleven (11) - $50,000 grant

About Panorama GlobalPanorama Global is a social impact nonprofit that empowers changemakers through radical collaboration. We help our partners navigate the winding path from vision to impact. 

What We Do

• Collaboratives - Hosting and supporting collaborative efforts to achieve common goals.
• Fiscal Sponsorship - Financial and administrative support providing lean operating models to jumpstart projects.
• Funds - Philanthropic vehicles to manage and distribute funds that fuel global initiatives.

About  Innovative Postsecondary Models Fund

The Innovative Postsecondary Models (IPM) Fund supports innovative postsecondary education models that are rethinking how education is designed, delivered, financed, and assessed for learners in the United States.

The Fund is interested in innovations that benefit all learners, but especially learners whom the data show encounter the greatest obstacles to opportunity. The goal of this Fund is not only to provide funding to innovative models, but also to learn from selected grantees on how to reduce barriers to postsecondary access and increase student success outcomes to help inform the role philanthropy can play in supporting higher education innovation.

What We're Funding

We are seeking innovative postsecondary education models that demonstrate, or have the potential to demonstrate, meaningful improvements in how learners access, experience, and benefit from postsecondary education. We seek approaches with the potential to scale, influence the field, and inform how postsecondary education evolves nationally.

To help illustrate the types of innovations we hope to support, we have organized this opportunity around four broad themes. These themes reflect key dimensions of postsecondary innovation that have the potential to improve learner outcomes and inform broader systems change.

All four themes are grounded in a shared principle: student-centeredness. Truly innovative postsecondary models must be designed around learner needs, especially the needs of learners whom the data show face the greatest barriers to access and success in traditional postsecondary education.

Applicants are not expected to address all four themes, but should demonstrate strong alignment with at least one of the following:

Reimagining Instructional Design, Delivery, Assessment, and Student Support

• What success might look like:
  • Innovative instructional models improve student persistence, completion, and post-completion success, particularly for historically underserved learners, while maintaining or reducing costs.
  • Learners benefit from personalized, adaptive instruction and competency-based assessments that enable them to demonstrate and document skills in ways that are recognized by employers and other educational institutions.

Advancing Affordability and Financial Sustainability

• What success might look like:
  • Learners spend less overall, face reduced financial risk, and access high-quality education pathways that lead to credentials supporting economic mobility.
  • Successful models demonstrate affordability not only through reducing costs for learners, but also by maintaining or reducing the cost of delivering high-quality education through sustainable, efficient approaches.

Career and Workforce Alignment

• What success might look like:
  • Work and learning are more demonstrably connected and flexible, with evidence that skills are more directly tied to credentials and real career opportunities.

Removing Barriers for Underserved Learners

• What success might look like:
  • More learners from backgrounds and communities who the data show have faced the greatest barriers to accessing postsecondary education are able to access, complete, and benefit from high-quality credentials.

About  USA Track & Field Foundation IncThe USA Track & Field Foundation was established in 2002. Our Foundation provides a means to attract and guide funds to new and innovative track & field programs, with an emphasis on providing opportunities for youth and elite athletes.Mission: To support the development of emerging elite athletes, while fostering integration within the broader track & field community. To facilitate the physical, educational, social and character development of youth track & field athletes and to help prepare them to mature and succeed in adult life.About Youth Club GrantThe USATF Foundation considers providing opportunities for youth athletes to compete in track & field a top priority. We encourage youth track clubs and programs from all areas of the United States to apply for financial assistance.Examples of allowable expenses are as follows: equipment, uniforms, meet fees, travel, facility rental, staff and volunteer training and outreach.  

The USA Track & Field Foundation was established in 2002. Our Foundation provides a means to attract and guide funds to new and innovative track & field programs, with an emphasis on providing opportunities for youth and elite athletes.

Mission: 

To support the development of emerging elite athletes, while fostering integration within the broader track & field community. To facilitate the physical, educational, social and character development of youth track & field athletes and to help prepare them to mature and succeed in adult life.About USATF Maternity GrantTo be considered for a USATF Foundation Maternity Grant, please begin by filling out the Elite Grant Application. Our Maternity Grant Committee will utilize the application information to consider your grant request. In addition to the Elite Grant Application please send along a formal letter for the committee to review. USATF Foundation is accepting formal letters of request for funding throughout the year. The Maternity Grant committee will consider and award grants on a quarterly basis dependent on available funding.

Please include in your letter:

• A detailed description of your current situation (expecting or recovering from childbirth)
• Timeline including estimated due date and estimated time frame when your training became affected by pregnancy
• Include your intentions and plans for after child birth
• List your most recent competition date where you were in peak form and the time / mark of the performance
• Were you ever ranked in the top 20 in the US or top 50 in the world within the 2 years before you became pregnant? If yes, please list the ranking, month/year and by what source.
• How Foundation funding would benefit you personally and in your track & field/running career.

The OVC FY 2026 Housing Assistance for Victims of Human Trafficking program aims to provide vital housing and support services for victims of human trafficking. This initiative, led by the U.S. Department of Justice, focuses on rapid rehousing, ensuring victims transition quickly into stable, permanent housing. Organizations interested in applying must demonstrate their capacity to deliver comprehensive support aligned with federal guidelines. Applications are due by October 5, 2026, through JustGrants.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Amyloidosis

Help with healthcare costs for amyloidosis

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Amyloidosis is characterized by a build-up in amyloid protein in specific organs or throughout the body. It is a rare disease that affects multiple systems. Subtypes include hereditary amyloidosis, light chain amyloidosis (AL amyloidosis), and amyloid A (AA) amyloidosis (secondary amyloidosis).

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

HIV, AIDS, and prevention

Help with healthcare costs for HIV, AIDS, and prevention

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

HIV, also known as human immunodeficiency virus or acquired immunodeficiency syndrome, is a virus that attacks the immune system. When left untreated, it can develop into AIDS. HIV is a chronic disease that affects the immune system.

The Hypercholesterolemia Grant by the Patient Advocate Foundation offers financial assistance to individuals diagnosed with hypercholesterolemia, helping cover out-of-pocket healthcare costs such as medication copays and insurance premiums. This nonprofit aims to improve patient access to necessary care while supporting over 3.8 million patients since its inception. Eligible applicants must have health insurance and meet specific income requirements to receive assistance in managing their healthcare expenses effectively.

The Hyperkalemia Grant, provided by the Patient Advocate Foundation, offers crucial financial assistance to patients struggling with hyperkalemia. This grant covers out-of-pocket healthcare costs, including medication copays and health insurance premiums. Eligible applicants must have a confirmed diagnosis and meet specific income and residency requirements. Since its inception, the foundation has supported millions of patients, ensuring they can access the necessary treatment and resources for their health needs.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS)

Help with healthcare costs for Multiple sclerosis (MS)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS) health equity

Help with healthcare costs for multiple sclerosis (health equity)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code. 

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Help with healthcare costs for Paroxysmal Nocturnal Hemoglobinuria (PNH)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Paroxysmal Nocturnal Hemoglobinuria (PNH), also known as Marchiafava– Micheli syndrome, is a rare disease that is characterized by impaired bone marrow function and destruction of red blood cells. PNH is a rare disease that affects the circulatory system.

The Periodic Paralysis Grant, offered by the Patient Advocate Foundation, assists individuals diagnosed with periodic paralysis in managing out-of-pocket healthcare costs. Eligible applicants must be in treatment or planning to begin treatment for this rare muscle disease. The fund covers various expenses, including medication copays and insurance premiums, ensuring that patients can afford essential care. With a mission to empower and support patients, this grant plays a crucial role in navigating healthcare challenges.

The Philadelphia Chromosome Negative Myeloproliferative Neoplasms (MPN) Grant, offered by the Patient Advocate Foundation, provides crucial financial assistance to patients facing this cancer type. It covers out-of-pocket healthcare costs, including medication copays and insurance premiums, ensuring those affected can access necessary treatments. With a focus on personalized case management, the foundation has supported millions in navigating their healthcare needs, emphasizing the importance of timely and affordable care for patients diagnosed with MPN.

The Richard L and Freda K Flerlage Foundation

Our Mission

Working to empower underserved populations through small grants in support of literacy, healthcare, reduction of poverty, and the promotion of social and environmental justice.

We are a small family foundation, when possible we aim to support organizations with relatively small operating funds where our small grants will have their greatest possible impact.

Our average grant is $3,800.

Our Mission

UNCF envisions a nation where all Americans have equal access to a college education that prepares them for rich intellectual lives, competitive and fulfilling careers, engaged citizenship and service to our nation.

UNCF’s mission is to build a robust and nationally-recognized pipeline of under-represented students who, because of UNCF support, become highly-qualified college graduates and to ensure that our network of member institutions is a respected model of best practice in moving students to and through college.

UNCF’s North Star is to increase the total annual number of African American college graduates by focusing on activities that ensure more students are college-ready, enroll in college and persist to graduation. This is done through a three-pillar strategy. Positioning member institutions as a viable college option for students and investing in institutional capacity to improve student outcomes; creating transformational support programs to ensure students are enrolling and persisting through college completion; building awareness of educational attainment and cultivating college-going behaviors within the African American community.

About the UNCF Lighted Pathways Program

Increasing the number of Black investment management professionals one opportunity at a time

According to The American College and the CFP Board, African Americans only make up 5% of financial advisors and 2% of certified financial planners (CFP), even though African Americans represent 13.4% of the U.S. population.

The UNCF Lighted Pathways programs meets the disparity and lack of Black talent in asset management through the UNCF Lighted Pathways initiative which provides scholarships and internships to African American undergraduate students interested in the investment management industry. Through this initiative, UNCF Lighted Pathways aims to create a career pathway to attract, develop, and retain Black talent for the asset management industry.

The UNCF Lighted Pathways Program excites, educates, and empowers young people by supporting personal and professional development, driving company performance, and providing the asset management industry the talent they need to meet today’s challenges and tomorrow’s opportunities. This program offers students a glimpse inside the dynamic, global asset management industries and the career opportunities, potential and rewards within them.

Students are afforded the opportunity to receive $5,000 in scholarships and/or participate in internships in the financial industry provided by the program’s partners.

The FY26 Bollards Competitive Grant Program aims to enhance pedestrian safety by funding bollard installation projects. This initiative targets areas frequented by large crowds to prevent injuries and potential acts of terrorism. Eligible applicants include State Departments of Transportation and local government entities, with a 100% federal funding share for projects. This program is vital for improving public safety in urban environments.

The Community Forest and Open Space Conservation Program, offered by the USDA Forest Service, aims to support Indian Tribes, local governments, and qualified non-profits in acquiring private forest lands to establish community forests. This competitive grant program focuses on protecting forestland from non-forest uses while enhancing public access and community benefits such as recreation and education. Applications are due by October 13, 2026, requiring coordination with State Foresters or Tribal officials.

The BJS FY 2026 National Incident-Based Reporting System Estimation Program aims to enhance statistical protocols for crime and arrest data collection in the U.S. This funding opportunity supports the ongoing development of the NIBRS Estimation System, focusing on improving data quality, timeliness, and estimation methodologies. By refining these processes, the program seeks to address public safety challenges and provide reliable national estimates, thereby ensuring effective law enforcement and crime prevention efforts.

The BJS FY 2026 Annual Surveys of Probation and Parole (ASPP) from 2026 to 2030 will provide crucial insights into individuals under community supervision in the U.S. By collecting comprehensive data on probation and parole populations, this initiative aims to report accurately on the dynamics and characteristics of correctional supervision. The data collection process will address various challenges, ensuring that the information reflects the realities of both large and small supervising agencies across the country.

The Women's Initiative for Screening and Health (WISH) aims to enhance women's health by increasing access to preventive services. This initiative brings together healthcare providers, academic institutions, and patient-centered organizations to improve the adoption of evidence-based guidelines for women's preventive health. By raising awareness and ensuring the guidelines are integrated into clinical practice, WISH addresses key health challenges faced by women throughout their lives.

The Food and Agricultural Sciences National Needs Graduate and Postgraduate Fellowships program, managed by the USDA's NIFA, aims to enhance the training of new graduate students in food and agricultural sciences. It provides essential funding for master's, DVM, and doctoral students, focusing on developing the next generation of experts to address critical needs in agricultural sciences. This initiative supports U.S. citizens and residents in achieving their educational goals and contributing to the USDA's mission.

The BJS FY 2026 Criminal History Record Assessment and Research Program (CHRARP) aims to enhance the Bureau of Justice Statistics' ability to analyze recidivism and criminal history data. This program will support the standardization of criminal records across jurisdictions, enabling accurate statistical analyses. By refining existing data coding systems and addressing data quality issues, the CHRARP will improve research on offenders' patterns and careers, ultimately contributing to effective criminal justice policies.

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

• Promote and support legal research and education;
• Advance the science of jurisprudence;
• Facilitate the administration of justice;
• Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Community Outreach Grant

The Community Outreach Grants Program is designed to support projects and initiatives that provide legal services in local communities. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity) and other organizations to develop and support projects that make a lasting impact on their communities.

Applicants may only receive one (1) Foundation grant per year.