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Best McCook County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in McCook County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.26B

Total funding

$5K

Median grant

9,000+ grants
$3.26B total
$5K median

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8,985 Results based on applied filters

National Animal Disease Preparedness and Response Program (NADPRP) FY 2027 Industry Preparedness Funding Opportunity

USDA: Animal and Plant Health Inspection Service (APHIS)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $4,000,000
The USDA Animal and Plant Health Inspection Service (APHIS) has announced a funding opportunity of up to $40 million for the National Animal Disease Preparedness and Response Program (NADPRP) FY 2027. This initiative aims to bolster readiness against foreign animal disease outbreaks by supporting high-value projects that enhance prevention, preparedness, response, and recovery capabilities in the agricultural sector. Eligible organizations include livestock producer and veterinary groups, with further details available on the USDA APHIS NADPRP website.
Agriculture Livestock & Ranching Veterinary Science & Services +2 more

OVW Fiscal Year 2026 Grants to Tribal Domestic Violence and Sexual Assault Coalitions Program

US DOJ: Office on Violence Against Women (OVW)
Federal Government
American Samoa, Guam +4 more
Up to US $342,358
The OVW Fiscal Year 2026 Grants to Tribal Domestic Violence and Sexual Assault Coalitions Program aims to support nonprofit, nongovernmental Tribal coalitions focused on domestic violence and sexual assault. Eligible applicants are recognized coalitions invited by OVW to apply. Each coalition will receive a base funding amount, with additional funds available for projects emphasizing sexual assault. This initiative seeks to strengthen resources for Indian Tribes and Native Hawaiian communities in addressing these critical issues.
Domestic Violence Sexual Assault / Abuse Human Trafficking +2 more

Flexible Funding Model - Advancing Domestic Mutual Reliance Through Strengthened Infrastructure Development and Maintenance for Manufactured Food Regulatory Programs

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
Puerto Rico, United States
Up to US $450,000
The Flexible Funding Model aims to enhance manufactured food regulatory infrastructure and foster mutual reliance in food safety. This initiative will support both new and existing programs in achieving compliance with the Manufactured Food Regulatory Program Standards (MFRPS). By promoting collaboration between manufactured food programs and the FDA, the initiative seeks to improve regulatory efficiency and effectiveness through shared data and coordinated enforcement efforts, ultimately ensuring high-quality food safety oversight.
Epidemiology & Public Health Community / Public Safety Food Safety +2 more

Project Rental Assistance Program of Section 811 Supportive Housing for Persons with Disabilities FY 2027

US HUD: Office of Housing-Federal Housing Commissioner
Federal Government
American Samoa, Guam +4 more
Up to US $7,094,211
The Project Rental Assistance Program of Section 811 supports innovative strategies to enhance access to affordable supportive housing for individuals with disabilities. This initiative fosters collaborations between State Housing Agencies and Health Services, aiming to increase the availability of supportive services. By empowering states to manage funds flexibly, the program addresses the critical shortage of integrated housing options, ensuring that eligible individuals receive necessary rental assistance effectively.
Disability Care & Services Community Development & Revitalization Real Estate & Housing +2 more

National Center on Elder Abuse Resource Center (364112)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $856,250 - US $1,000,000
The National Center on Elder Abuse Resource Center aims to enhance the readiness of communities to combat elder abuse, neglect, and exploitation. By offering resources, training, and information, the center empowers professionals and the public to effectively prevent and respond to elder maltreatment, ensuring that older Americans can live with dignity and independence. This initiative, supported by the US HHS Administration for Community Living, emphasizes best practices and awareness to mitigate risks associated with elder fraud and scams.
Senior Services Human & Social Services Violence Prevention

Alzheimer's Disease Programs Initiative (ADPI) - States and Community Grants (364113)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $850,000 - US $1,000,000
The Alzheimer's Disease Programs Initiative (ADPI) offers State and Community Grants to enhance dementia-capable home and community-based service systems. Option A targets state agencies to develop sustainable HCBS systems, while Option B focuses on community-based organizations to fill service gaps for individuals with dementia. Both options aim to provide quality support for those living with dementia and their caregivers, fostering independence and safety in their communities.
Disability Care & Services Senior Services Neurological Diseases & Disorders +2 more

Elder Justice Innovation Grants FY2027

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $250,000 - US $500,000
The Elder Justice Innovation Grants for FY2027 aim to foster innovative solutions to elder justice issues, enhancing prevention and intervention strategies against elder abuse. Projects funded under this program will focus on developing and disseminating effective materials and programs, contributing to a robust evidence base in the field. This initiative by the US HHS: Administration for Community Living supports efforts that can be replicated across communities, promoting greater awareness and support for elder individuals.
Senior Services Human & Social Services Crime Victim Services +1 more

Alzheimer's Disease Programs Initiative (ADPI) - Dementia Capability in Indian Country (364115)

US HHS: Administration for Community Living (ACL)
Federal Government
United States
US $200,000 - US $300,000
The Alzheimer's Disease Programs Initiative (ADPI) aims to develop dementia-capable home and community-based service systems in Indian Country over a 36-month period. This initiative is designed for federally recognized tribes and organizations, promoting person-centered services that support individuals with dementia and their caregivers. Applicants can choose between two options: enhancing existing programs or establishing new dementia services, ensuring tribal leadership support and community engagement throughout the process.
Senior Services Neurological Diseases & Disorders Health Care Access & Delivery +2 more

Alheimer's Disease Programs Initiative (ADPI) - State Programs for Dementia Specific Respite (364114)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $4,000,000
The Alzheimer's Disease Programs Initiative (ADPI) aims to enhance support for unpaid family caregivers by expanding access to high-quality, dementia-specific respite services. This initiative, funded by the US HHS Administration for Community Living, focuses on reducing caregiver burden and delaying institutionalization for individuals with Alzheimer's disease or related dementias. By partnering with aging service providers, the program ensures caregivers receive necessary training and support, fostering a sustainable and responsive respite care system.
Senior Services Neurological Diseases & Disorders Family Services +2 more

No Wrong Door System Modernization: Connecting People to Services

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
The No Wrong Door System Modernization funding aims to enhance access to services for older adults, people with disabilities, and caregivers. By modernizing NWD systems, states can improve service navigation through innovative strategies and technology, including AI. This initiative supports the Administration for Community Living's efforts to connect individuals to vital resources and build evidence on effective service access methods, ensuring a person-centered approach to community living.
Disability Care & Services Senior Services Health Care Access & Delivery +2 more

Evaluating Innovative Community Based Nutrition Models that Improve Health Outcomes for Older Adults in Senior Nutrition Programs

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $400,000 - US $439,520
This funding opportunity from the US HHS Administration for Community Living aims to support innovative community-based nutrition models that enhance health outcomes for older adults participating in Senior Nutrition Programs. Projects should focus on improving access to healthy foods, promoting healthy aging, and developing sustainable practices. By fostering community partnerships, the initiative seeks to replicate successful strategies across the Aging Network, ultimately improving the quality of life for seniors nationwide.
Disability Care & Services Senior Services Health Care Access & Delivery +2 more

Wine Marketing & Research Program Funding

Pennsylvania Department of Agriculture (PDA)
State/Local Government
Pennsylvania, United States
Unspecified amount

Pennsylvania Department of Agriculture

The Pennsylvania Department of Agriculture encourages, protects and promotes agriculture and related industries throughout the commonwealth while providing consumer protection through inspection services that impact the health and financial security of Pennsylvania's citizens.

Wine Marketing & Research Program

Introduction

The Pennsylvania Wine Marketing and Research Program Board (Board) annually, or more frequently as the availability of the fund permits, solicits applications for grants to conduct promotion, marketing and research projects to increase the quality, profitability, production and sale of wines, enhance the wine industry and benefit wine producers of this Commonwealth.

Research includes, but is not limited to:

  • Characterization of Accentuated Cut Edges (ACE)
  • Impacts of Spotted Lanternfly
  • Impact of Under-trellis Groundcover
  • Marketing Education and Professional Development for the PA Wine Industry
  • Pennsylvania Wine Land Statewide Marketing & Promotions
  • Spotted Wing Drosophila in Pennsylvania
  • Grapevine Leafroll Viruses
  • Tannin Extraction
Viticulture

Young Faculty Award (YFA) 2027

US DOD: Advanced Research Projects Agency
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The Young Faculty Award (YFA) 2027, sponsored by the Defense Advanced Research Projects Agency (DARPA), seeks to support emerging researchers in academia and non-profit research institutions. This program focuses on those without previous DARPA funding, aiming to align innovative research with national security needs. By providing significant funding, the YFA encourages the development of transformative capabilities for the Department of War, fostering the next generation of researchers dedicated to addressing critical national security challenges.
Engineering Education - Higher Education Science +1 more

FY 2027 - 2029 Broad Agency Announcement (BAA), Oceanic and Atmospheric Research (OAR)

National Oceanic and Atmospheric Administration (NOAA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The FY 2027 - 2029 Broad Agency Announcement by NOAA seeks proposals for innovative research and projects through the Cooperative Ecosystem Studies Unit (CESU) program. This initiative connects federal agencies with diverse partners to address ecological challenges. It encourages efforts that enhance understanding of weather and environmental systems while ensuring the conservation of marine resources. Funding is contingent on appropriations, and applications are subject to an administrative review process.
Natural Resources Atmospheric Sciences Marine / Ocean Conservation +1 more

Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource-Constrained Settings--Implementation Science Network (PATC3H-IN)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The PATC3H-IN initiative focuses on improving HIV care for adolescents in resource-constrained settings while generating evidence that can enhance care models in the United States. By developing scalable care delivery strategies and studying their impact, the project aims to address barriers faced by young people, such as stigma and access issues. This research is crucial for achieving effective interventions, ultimately helping to reduce new HIV infections and improve health outcomes for adolescents both domestically and globally.
Epidemiology & Public Health Infectious & Parasitic Diseases HIV / AIDS +1 more

Discovery Gateway to Reproductive Health Innovation

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Discovery Gateway to Reproductive Health Innovation, established by the NICHD, aims to create a comprehensive knowledgebase to advance research on various reproductive health conditions like preeclampsia and infertility. This initiative will integrate clinical and multi-omic data to bridge critical knowledge gaps, enabling scientists to generate insights that could lead to new treatments and commercial products, thereby accelerating public-private partnerships and improving health outcomes.
Health & Medicine Genetics & Genomics Women's Health +1 more

Learning Disabilities Research Centers

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Learning Disabilities Research Centers program, supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, aims to enhance outcomes for children with learning disabilities such as dyslexia and dyscalculia. This initiative promotes collaborative research to improve SLD identification, understanding genetic factors, and testing innovative interventions. By fostering mentorship and collaboration, the program seeks to empower the next generation of researchers and enhance educational strategies for affected youth.
Disability Care & Services Genetics & Genomics Education - K through 12

CAPSTONE Centers for Multidisciplinary Research in Child Abuse and Neglect

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The CAPSTONE Centers for Multidisciplinary Research in Child Abuse and Neglect aims to address the critical public health issue of child sexual abuse (CSA). This initiative focuses on overcoming research challenges and enhancing data infrastructure to support innovative studies on CSA interventions and long-term health outcomes. By emphasizing prevention and translational research, the Centers seek to create measurable impacts on public health, thus contributing to the well-being of affected children and communities.
Epidemiology & Public Health Crime Victim Services Violence Prevention

Agri-Business Access Grants Program

South Dakota Department of Transportation (SDDOT)
State/Local Government
South Dakota
Up to US $600,000

South Dakota Department of Transportation (SDDOT)

The mission of the South Dakota Department of Transportation is to provide a safe and efficient public transportation system. Our Vision is focused on better lives through better transportation.

Agri-Business Access Grants Program

The Department of Transportation Agri-Business Access Grants Program is a means for local governments to address road needs associated with new agri-business, such as ethanol plants, largescale elevators, etc. In many cases, these new agri-businesses create additional truck traffic that an existing road may not be built to take. SDDOT works closely with the staff of the Governor’s Office of Economic Development (GOED) regarding these grants. The grant amount is a maximum of $600,000. Grants apply to the construction of roads meeting minimum program criteria and serving as the primary access to an agriculture-related business. The state provides 80% of the project costs on a reimbursement basis. The local government is responsible for all right-of-way acquisitions, utility costs, and design and construction engineering costs. The local government is responsible to let the project to bid.

Agricultural Economics Agricultural Crops Public Infrastructure

Sawyer Foundation Grant

Sawyer Foundation Charitable Tr
Private
United States
US $1,000 - US $25,000

About Sawyer Foundation Charitable Trust Our mission is to support partner organizations that share the gift of clean drinking water to under-resourced communities. Our vision is to see all of our global community have access to clean, safe drinking water.Through our partnership with Sawyer, our nonprofit partners have access to affordable, point-of-use filters designed to provide reliable access to clean water for 10+ years.‍

Sawyer partners with over 140 non-profits in more than 100 countries, providing clean water to families lacking access to clean water – for long-term relief and in disaster situations.About Sawyer Foundation Grant We prioritize projects that demonstrate a strong commitment to:

  • Long-term sustainability in water filtration and access.
  • Training, follow-up, and local engagement that strengthen best practices.
  • Data collection or research that improves project implementation and outcomes.
  • Unique expertise, partnerships, or approaches that enhance global impact.
Sanitation & Clean Drinking Water

FY26 DRL/IRF Global Request for Statements of Interest

US Department of State: Bureau of Democracy, Human Rights and Labor (DRL)
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $3,000,000
The FY26 DRL/IRF Global Request for Statements of Interest invites organizations to submit proposals aimed at promoting religious freedom. This global competition allows for up to five statements of interest from each organization, focusing on addressing restrictions on religious freedom aligned with U.S. foreign policy. Programs funded will support the principles established by the International Religious Freedom Act and Executive Order 13926, emphasizing religious freedom as a moral and national security imperative.
Social Justice / Human Rights Interfaith Cooperation / Religious Freedom International / Foreign Affairs +1 more

Fiscal Year 2027 Counter Unmanned Aircraft Systems (C-UAS) Grant Program

Department of Homeland Security - FEMA
Federal Government
American Samoa, Guam +4 more
US $760,000 - US $25,000,000
The Fiscal Year 2027 Counter Unmanned Aircraft Systems (C-UAS) Grant Program allocates $250 million to enhance public safety through advanced UAS Detection, Identifying, Monitoring, Tracking, and Mitigation technologies. This funding focuses on supporting law enforcement agencies in safeguarding critical infrastructure and public events, particularly the 2028 Summer Olympics and Paralympics in Los Angeles, designated as a National Special Security Event. The program aims to build national detection capacity and ensure effective interagency coordination.
Domestic / Homeland Security Community / Public Safety Emerging Technology Development +1 more

Institute of Education Sciences (IES): National Center for Special Education Research (NCSER): Transformative Research in Special Education, Assistance Listing Number (ALN) 84.324T

US ED: Institute of Education Sciences (IES)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Institute of Education Sciences (IES) invites transformative research proposals aimed at addressing critical challenges in special education. The FY 2027 focus is on developing innovative preservice teacher education solutions that enhance the recruitment, training, and retention of both general and special education teachers. This initiative aims to significantly improve educational outcomes for students with disabilities, fostering high-quality instruction and scalable solutions to benefit future educators.
Disability Care & Services Education - K through 12 Special Needs Education +1 more

Institute of Education Sciences (IES): National Center on Education Research (NCER): From Seedlings to Scale, Assistance Listing Number (ALN) 84.305J (364086)

US ED: Institute of Education Sciences (IES)
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The Institute of Education Sciences (IES) is launching the From Seedlings to Scale (S2S) Grants program to foster innovative educational solutions. Focused on integrating evidence into policy and practice, the program invites Phase One applications under the Coordinating Systems to Translate Evidence into Policy and Practice (C-STEP) area. Projects must utilize AI and technology to enhance education systems, ensuring alignment with evidence-based practices for improved outcomes for students from prekindergarten to grade 12.
Education - K through 12 Community / Public Safety Emerging Technology Development +1 more

FY 2027 – 2029 Broad Agency Announcement (BAA), National Marine Fisheries Service

National Oceanic and Atmospheric Administration (NOAA)
Federal Government
Puerto Rico, United States +1 more
Unspecified amount
The FY 2027 – 2029 Broad Agency Announcement (BAA) by the National Marine Fisheries Service invites innovative research and educational projects that enhance NOAA's mission. This funding opportunity focuses on applied environmental and cultural resource research, technical assistance, and education to promote effective stewardship of public lands. Please note that the availability of funds is contingent on appropriations, and this announcement does not guarantee project funding or review beyond initial administrative checks.
Environmental Education Natural Resources Historic Preservation

Public Humanities Projects (364098)

National Endowment for the Humanities
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $2,000,000
The National Endowment for the Humanities (NEH) is inviting applications for the Public Humanities Projects program, aimed at enhancing public understanding of the humanities through exhibitions, historic site interpretations, and public lectures. For 2027, topics of interest include Western civilization, literature, the 250th anniversary of the American Revolution, civic education, and cultural literacy. This initiative seeks to foster civil discourse and engage communities in meaningful discussions.
Art & Culture Humanities & Social Science Historic Preservation +2 more

Perkins Reserve Grant

South Dakota Department of Education
State/Local Government
South Dakota
US $10,000 - US $50,000

South Dakota Department of Education

The South Dakota Department of Education is dedicated to enhancing learning through leadership and service. The South Dakota Department of Education's aspiration is for all students to leave the K-12 education system College, Career and Life Ready.

Perkins Reserve Grant

Applications may be submitted by public school districts with approved Career & Technical Education programs (or those wishing to add approved CTE program in the 2026-27 school year). Perkins Reserve Grants will provide funds to specifically target the following needs:

  • Special Populations:
    • How can you support and bridge the gap for: English learners, students on IEPs or 504 plans, economically disadvantaged, single parent or students caring for siblings, foster, homeless, and/or students with transportation concerns. Details how the grant will support student achievement and develop industry-related skills.
  • Industrial Alignment:
    • How can you enhance the current program with equipment industry or technical colleges are using right now? Selected equipment, curricula or professional development opportunities reflect current industry standards.
  • Innovative Delivery:
    • How the grant proposal fosters innovation in the CTE program. Examples: Work-based learning opportunities (summer, remote, etc.), solutions to overcome workforce desert challenges, remote CTE instruction, industry engagement, etc. 
Workforce Preparation & Job Readiness Vocational & Trade Education Academic Success & Enrichment +2 more

McCook County Grants for Nonprofits Highlights

Looking for McCook County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all McCook County grants recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in McCook County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the McCook County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for McCook County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538