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Best McCook County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in McCook County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.26B

Total funding

$5K

Median grant

9,000+ grants
$3.26B total
$5K median

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8,985 Results based on applied filters

DARRP Restoration Implementation Grants (2026)

National Oceanic and Atmospheric Administration (NOAA)
Federal Government
American Samoa, Guam +4 more
US $2,500,000 - US $100,000,000
The DARRP Restoration Implementation Grants aim to enhance marine and coastal habitat restoration through collaboration between NOAA and non-federal partners. These grants address oil spills and hazardous substance releases by supporting restoration activities authorized under various environmental laws. Eligible applicants will implement projects that promote sustainable fisheries, recover endangered species, and boost local economies. Through careful planning and evaluation, recipients will contribute to effective restoration strategies that align with NOAA's mission and the needs of coastal communities.
Habitat & Ecosystem Restoration Marine / Ocean Conservation Environmental Contamination & Pollution +2 more

ROSES 2025: A.16 Cryosphere

National Aeronautics and Space Administration (NASA)
Federal Government
United States
Unspecified amount
The ROSES 2025: A.16 Cryosphere program by NASA focuses on the vital role of Earth's ice within the global climate system. It aims to enhance understanding of cryospheric processes through satellite and airborne observations, addressing the challenges posed by the remoteness of icy regions. The program supports research on Antarctic and Greenland ice sheets, glaciers, and Arctic sea ice to monitor changes and their impacts on sea level rise, ocean biology, and climate feedback mechanisms.
Earth Science Climatology Glaciology +2 more

PFE: Research Initiation in Engineering Formation (PFE: RIEF)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
More than US $200,000
The Professional Formation of Engineers: Research Initiation in Engineering Formation (PFE: RIEF) program aims to foster research in the Professional Formation of Engineers (PFE) while expanding the community of researchers in this field. It targets early-career Principal Investigators (PIs) with limited experience in social science or education research, enabling them to develop expertise in engineering education research and address critical challenges in engineering formation.
Engineering Education - Higher Education Workforce Preparation & Job Readiness +2 more

Amy Adina Schulman Memorial Fund Grant

Amy Adina Schulman Memorial Fund
Association/Society
Canada, United States
Unspecified amount
The Amy Adina Schulman Memorial FundThe Amy Adina Schulman Memorial Fund is a Princeton, New Jersey-based endowment fund providing grants to individuals, young adults who volunteer or intern for progressive social action projects or programs in an area of their interest and commitment. The Amy Adina Fund also sponsors a lecture each year on a relevant and timely topic related to its educational mission.The Amy Adina Schulman Memorial Fund was started in 1987 one year after Amy Adina, 20, died suddenly while a student and activist at Rutgers University. It is a realization of her family and her communities’ desire to celebrate her life, to fulfill her dreams and her potential. Since its inception, almost 1,500 grants have been awarded for work in Africa, Asia, Latin America, the Middle East, and the United States—nearly $1,000,000 in total. The Amy Adina Schulman Memorial Fund is a 501(c)3 nonprofit organization.About Our GrantsSmall grants (depending on length of service), are awarded to as many applicants as possible rather than giving larger amounts to fewer individuals. The number of awards has grown each year thanks to annual contributions as well as to gifts sent to the Fund to honor special occasions and life cycle events.
Social Justice / Human Rights Environment Poverty Alleviation & Services +4 more

DoW Breast Cancer, Clinical Research Extension Award (363671)

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The FY26 Breast Cancer Research Program's Clinical Research Extension Award aims to enhance breast cancer clinical studies by extending data collection and follow-up. This funding mechanism emphasizes the importance of patient participation and addresses challenges from early trial terminations. Notably, applications must include two breast cancer consumer advocates and can feature either a single Principal Investigator or a duo. This initiative seeks to improve outcomes through comprehensive data analysis and patient engagement.
Breast Cancer

DoW Breast Cancer, Breakthrough Award Levels 1 and 2 (363670)

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $750,000 - US $3,350,000
The FY26 Breast Cancer Research Program's Breakthrough Award supports transformative research aimed at significant advancements in breast cancer treatment. This award offers various funding levels, including Population Science Studies, allowing for innovative approaches that can lead to clinical applications. Each application must align with overarching BCRP challenges, ensuring a focus on impactful research. The program acknowledges both individual and collaborative Principal Investigators, emphasizing the importance of timely submissions to avoid administrative issues.
Breast Cancer

Translational Research in Maternal and Pediatric Pharmacology and Therapeutics

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is set to renew a Notice of Funding Opportunity (NOFO) focused on advancing translational research in maternal and pediatric pharmacology. This initiative aims to enhance precision medicine by developing innovative tools and therapeutics for pregnant and lactating women, infants, and children. The goal is to improve the safety and efficacy of medications while ensuring effective patient-provider communications. Applications are not currently being solicited.
Pharmacology Children’s Health & Pediatrics Women's Health +1 more

Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC) program is designed to enhance research on muscular dystrophy through a collaborative, center-based approach. By fostering interdisciplinary projects and providing essential training for emerging scientists, the MDSRCs aim to drive innovation in both basic and clinical research. Engaging patient and advocacy communities is a key component, ensuring research is patient-centered and informed by real-world needs. This initiative is supported by various legislative authorities.
Muscular Dystrophy

Multimodal AI to Accelerate Precision Medicine for Type 1 Diabetes (U01- Clinical Trials Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health is funding a groundbreaking project to enhance our understanding of Type 1 diabetes (T1D) through multimodal AI. This initiative aims to integrate diverse datasets to explore the interactions of biological processes in T1D development. By leveraging advanced AI models, the research will uncover critical insights, identify biomarkers, and pave the way for personalized medicine approaches, ultimately improving prevention and treatment strategies for this complex disease.
Diabetes

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The SCORCH Program: Phase 2 aims to enhance the understanding of single cell biology in the context of HIV and Substance Use Disorder (SUD). Building on previous research, this initiative will explore new single cell approaches to investigate the interactions between SUD and HIV progression at various biological levels. By leveraging advanced techniques, the program seeks to identify candidate mechanisms and potential therapeutic targets, ultimately contributing to innovative solutions for SUDs and HIV-related challenges.
HIV / AIDS

Modernizing Violent Death and Suicide Surveillance Using the National Violent Death Reporting System (NVDRS)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $966,085
The National Violent Death Reporting System (NVDRS) is a crucial surveillance initiative by the CDC aimed at understanding violent deaths and suicides. This funding opportunity supports state and local entities in modernizing NVDRS, enhancing data collection and reporting processes. Key activities include timely data updates, modernization assessments, and pilot projects for improved data systems. The goal is to create a sustainable national surveillance system that provides reliable data to inform public health actions and enhance violence and suicide prevention efforts.
Computer Science & Engineering Suicide Prevention Violence Prevention

Team and Club Support

The Usa Track & Field Foundation Inc
Private
United States
Unspecified amount

About USA Track & Field Foundation Inc

The USA Track & Field Foundation was established in 2002. Our Foundation provides a means to attract and guide funds to new and innovative track & field programs, with an emphasis on providing opportunities for youth and elite athletes.

Mission: 

To support the development of emerging elite athletes, while fostering integration within the broader track & field community. To facilitate the physical, educational, social and character development of youth track & field athletes and to help prepare them to mature and succeed in adult life.Team and Club SupportThe USA Track & Field Foundation may be able to provide support to certain Elite Track & Field / Running clubs in the US.

Sports & Athletics

She Plus Foundation Grants

She Plus Foundation
Private
United States
Unspecified amount

About She+ Foundation The SHE+ Foundation, formerly known as The Patty Brisben Foundation for Women’s Sexual Health, was founded by Patty Brisben in 2005 after she recognized the profound need for a movement to address the too often ignored aspects of women’s sexual health. The SHE+ Foundation is committed to changing the narrative. We are here to advocate, educate, and fund research that advances the understanding and treatment for women’s sexual health, and improves quality of life for all women.Mission: Our mission is to advance women's sexual health and well-being through groundbreaking research, comprehensive education, and unwavering support. We strive to eradicate stigma, empower women with knowledge, and ensure equitable access to quality healthcare for all, regardless of socioeconomic status, race, or geography.About She+ Foundation GrantWe fund a wide range of projects that align with our mission to advance women's sexual health. This includes:

  • Research Studies: Clinical and academic research aimed at understanding and improving women's sexual health.
  • Educational Programs: Initiatives that provide education and awareness on topics related to women's sexual health.
  • Community Outreach: Programs that engage and support local communities, offering resources and support for women's sexual health.
  • Innovative Treatments: Development and implementation of new treatments and therapies for women's sexual health issues.

Women's Health

Geosciences Core Research: Atmospheric, Geospace, Earth and Ocean Sciences (GEO Core)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NSF Geosciences Core Research program funds innovative projects across atmospheric, geospace, earth, and ocean sciences. It encourages proposals that push the boundaries of knowledge in fundamental research, promoting interdisciplinary approaches. This initiative seeks transformative ideas that may not have immediate commercial applications but are crucial for advancing scientific understanding and addressing complex environmental challenges. Researchers are invited to explore various domains or integrate multiple disciplines to enhance our comprehension of the Earth and its systems.
Geoinformatics & Geospatial Sciences Earth Science Oceanography

Rural Communities Opioid Response Program - Overdose Response

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Up to US $300,000
The Rural Communities Opioid Response Program - Overdose Response aims to enhance healthcare access in rural areas by addressing urgent needs related to substance use disorder services. This initiative focuses on reducing overdose risks through targeted interventions and support, ensuring that rural communities receive necessary assistance. Funded by the Health Resources and Services Administration, this program is crucial for mitigating the opioid crisis in underserved regions, improving health outcomes, and promoting overall community well-being.
Community Services Rural Development Addiction & Substance Use Disorders +1 more

Rural Communities Opioid Response Program - Child and Adolescent Behavioral Health

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Up to US $1,000,000
The Rural Communities Opioid Response Program focuses on enhancing behavioral health care services for children and adolescents in rural areas. By providing essential funding, this initiative aims to tackle mental health and substance use disorders, ensuring that young individuals receive the support they need. The program, administered by the Health Resources and Services Administration, is crucial in addressing the unique challenges faced by rural communities, promoting healthier outcomes for future generations.
Community Services Addiction & Substance Use Disorders Drug Use Disorder

WEF Professional Development Grant

Wallingford Education Foundation (WEF)
Association/Society
United States
US $1,000 - US $2,000

Wallingford Education Foundation

Our Mission

The Wallingford Education Foundation is a non-profit, community-based partnership supporting educational innovation and excellence in our town.

Our Vision

The Wallingford Education Foundation empowers ideas and enhances educational experiences for students, educators and community members. It provides financial support outside the education budget that is aligned with the goals and focus areas of the school district’s strategic plan.

Professional Development Grant

Transformative impacts often result from staff members who choose to attend professional development programs. Typically, these opportunities are funded through the town’s annual school budget. However, the district may not be financially able to meet each request. Through the Professional Development Grant program, the Wallingford Education Foundation (WEF) provides additional funding for employees of Wallingford Public Schools to attend conferences hosted outside the district.

The Professional Grant program offers paired grants of $1,000 each for two Wallingford Public Schools staff members to attend the same professional development opportunity together OR single grants of up to $2,000 for an individual to attend a conference alone. Multiple grants are awarded yearly.

Teacher Development & Training

Spirit of Blue Safety Grant

Spirit of Blue Foundation
Private
U.S. Territories, United States
Unspecified amount

About Spirit of Blue

Our Vision

To become the nation’s leading supplemental provider of law enforcement safety equipment and training across the county.

Our Mission

Spirit of Blue is dedicated to the enhancement of officer safety throughout the law enforcement community by fulfilling unfunded safety equipment and training needs.

Safety Grant Program

Spirit of Blue’s primary initiative is the granting of safety equipment and training to municipal, county and state law enforcement agencies in an effort to protect their sworn personnel. 

Most grants are 100% funded, meaning that no match is required. In the majority of cases, Spirit of Blue conducts the procurement of the goods or services being granted so that the recipient agency isn’t burdened with having to negotiate prices, place orders or track delivery. Rarely, if ever, does Spirit of Blue provide cash awards. Once selected, Spirit of Blue will provide the recipient agency with an official grant award letter outlining everything that is contained in the award. The recipient agency must gain acceptance of the grant, whether on the authority of their agency head or by working with their local governing authority as their policy may dictate. There are no reporting requirements after the award of the grant, but agencies are asked to submit a photo to be used in the announcement of their grant.

Grant Application

The Spirit of Blue Safety Grant Program is designed to award equipment, or in some cases training, that will protect officers serving on duty. You should only request items that you can articulate will have a positive impact on officer safety.

Police & Law Enforcement Community / Public Safety

Al Lucas Memorial Scholarship Fund

Community Foundation of Central Georgia
Private
United States
US $1,000

About

The Community Foundation of Central Georgia was founded in 1993 by a group of citizens interested in encouraging philanthropy and strengthening communities.

The Foundation provides donors a simple, powerful, and highly personal approach to giving. Through their funds, CFCG donors support the causes and organizations that they care about, which enhances the quality of life for the people of Central Georgia.

Our vision is a Central Georgia where philanthropy thrives, communities are strong, and citizens work toward common goals.

Al Lucas Memorial Scholarship Fund

Albert James “Big Luke” Lucas was born September 1, 1978, to David E. and Elaine H. Lucas. He passed away on April 10, 2005, from a spinal cord injury he suffered during a Los Angeles Avengers arena football game. He was married to De’Shonda, and had a daughter, Mariah.

Al was a native of Macon, Georgia, graduating from Northeast High School in 1996. Following graduation, he attended Troy State University on a full athletic scholarship, and shined as a defensive lineman for the Trojans. Throughout college Al studied hard and cherished his time on the field and in 2000 was awarded the distinguished Buck Buchanan Award as the top defensive player in Division 1-AA. He was also an outstanding member of Omega Psi Phi Fraternity, Inc. He graduated in 2000 with a Bachelor of Science degree in Criminal Justice. Al went on to join the National Football League, signing as a free agent with the Pittsburgh Steelers and later playing for the Carolina Panthers. Later he joined the Arena Football League, playing for the Tampa Bay Storm, and finally the Los Angeles Avengers.

Al was a strong athlete with a heart of gold who believed in giving back to the community that supported him over the years. He especially loved working with children and served as a substitute teacher and coach at Northeast High School during the off-season. He was a member of Steward Chapel A.M.E. Church where he first learned the responsibility and power of tithing.

Al Lucas exemplified the characteristics of a scholar-athlete. He loved athletics, but knew his studies came first. He served his community and the Lord. He expected the best of himself and others. He excelled on the football field and in life. Recipients of the Al Lucas Memorial Scholarship will reflect Al’s ideals and carry on his legacy of excellence.

Purpose

  • To honor the memory of Al Lucas by providing college scholarships to scholar athletes in Al’s hometown of Macon, Georgia.

Awards

  • Amount of Award: $1,000, non-renewable.
  • Number of Awards: 7 per year. Two awards will be given to scholar-athletes graduating from Northeast High School, Al’s alma mater. One winner shall be female and one male. The other five awards will be given to student-athletes from each of the other five Bibb County public high schools. One will be awarded at each school.
Education - Higher Education Education - High School Academic Scholarship Programs

Epilepsy Wellness Advocates Research Grants

Epilepsy Wellness Advocates (EWA)
Private
United States
Unspecified amount

About 

Epilepsy Wellness Advocates (EWA) is a privately funded, research-informed organization focused on improving the quality of life for people living with epilepsy through collaborative partnerships and wellness-centered initiatives.

Free from pharmaceutical or institutional influence, we are committed to developing and supporting unbiased, evidence-based approaches to epilepsy management. Our efforts center on empowering individuals, families, and the organizations that serve them with practical tools, education, and support.

Epilepsy management extends far beyond clinical settings. Together with our partners, we’re building new ways to live well with epilepsy.

Epilepsy Wellness Advocates Research Grants

Epilepsy Wellness Advocates is dedicated to improving the quality of life for people with epilepsy by funding innovative research, and impactful programs with our long-term strategic partnerships for epilepsy management through alternatives to pharmacological or surgical avenues.

We collaborate with leading organizations, researchers, and wellness providers to understand and develop integrative and wellness health solutions that enhance the daily lives of those living with epilepsy. Our goal is to enable our partners and providers to impact as many people with epilepsy as possible and provide them with the tools and resources they need to reduce the impact of epilepsy on people’s lives.

Categories of Grant Funding:

  • Epilepsy Integrative Wellness Programs
  • Epilepsy Integrative Wellness Research Studies
  • Epilepsy Education and Toolkit Programs
  • Epilepsy Education Scholarships & Education Emergency Supports

Program Outcomes of Grants:

  • Improve quality of life and functional outcomes for people with epilepsy (PWE) and their caregivers.
  • Reduce seizure frequency, severity, and overall seizure burden through evidence-informed approaches.
  • Advance personalized, whole-person epilepsy management that reduces reliance on trial-and-error care.
  • Increase access to epilepsy wellness information, programs, and tools for PWE, caregivers, and providers.
  • Empower caregivers as essential partners by strengthening their education, tools, and ability to navigate care systems.
  • Translate research into practical, day-to-day resources that improve real-world epilepsy management and decision-making.
  • Drive innovation in epilepsy wellness and integrative care, including the development and validation of scalable management models.
  • Address comorbidities, side effects and other treatment burdens, and lifestyle factors that materially affect epilepsy outcomes and daily functioning.
  • Strengthen the epilepsy workforce and future provider pipeline, ensuring providers understand and are trained to treat epilepsy as a whole-person condition.
  • Reduce stigma and social isolation that negatively impact independence, dignity, and participation for PWE.
Brain Injuries Wellness & Healthy Living

Substance Abuse Prevention, Treatment, and Aftercare

Indian Health Service
Federal Government
United States
Unspecified amount
The Substance Abuse Prevention, Treatment, and Aftercare program aims to combat substance abuse in American Indian and Alaska Native populations. It focuses on enhancing care coordination, expanding culturally competent behavioral health services, and implementing early intervention strategies for at-risk youth. By supporting Tribal and community-led initiatives, the program fosters collaboration among families, youth, and community partners to create effective prevention, treatment, and recovery solutions.
Mental Health & Psychiatric Diseases Addiction & Substance Use Disorders Native American Services +1 more

McCook County Grants for Nonprofits Highlights

Looking for McCook County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all McCook County grants recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in McCook County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the McCook County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for McCook County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538