Skip to main content
Main content

Best McCook County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in McCook County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.26B

Total funding

$5K

Median grant

9,000+ grants
$3.26B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,017 Results based on applied filters

Individual Grants for Speech Therapy, Therapeutic Summer Camps, or Assistive Devices

Small Steps in Speech
Association/Society
United States
Unspecified amount
Small Steps in Speech is offering Individual Grants for Speech Therapy, Therapeutic Summer Camps, or Assistive Devices. Effective February 2, 2024, families with a joint household income of up to $125,000 can apply. Eligible applicants are U.S. citizens aged 3-22. Grants are not solely based on financial need, and previous grant recipients from SSIS may not reapply. Detailed eligibility and application requirements are outlined to ensure fair access to necessary support.
Speech Rehabilitation Speech-Language Learning & Disorders

Special Angels Foundation Grant

Special Angels Foundation
Association/Society
United States
Unspecified amount
The Special Angels Foundation Grant provides essential support for children with special needs, focusing on accessible therapy within established networks. Due to high demand, applications from outside California are temporarily suspended. The grant covers therapy expenses and requires a letter of medical necessity from a pediatric professional. Applicants must be under 18 and reside in the U.S. The foundation aims to maximize impact by prioritizing in-network resources and ensuring financial clarity for families.
Disability Care & Services

UHCCF Medical Grant

Unitedhealthcare Children's Foundation
Private
United States
US $5,000 - US $10,000
The UHCCF Medical Grant provides financial assistance to families with children under 16 years old who need access to medical services not fully covered by insurance. The grant offers up to $5,000 per year, with a lifetime maximum of $10,000. Families can apply regardless of their insurance provider, and the grant covers a wide range of medical expenses, ensuring children receive essential health care. Applicants must meet specific income and eligibility criteria to qualify for funding.
Children With Disabilities

Varghese Summersett Autism Scholarship

Varghese Summersett
Association/Society
United States
US $500
The Varghese Summersett Autism Scholarship aims to support children diagnosed with autism who require financial assistance for educational or recreational opportunities. Offered by Varghese Summersett, this scholarship reflects the commitment to enhancing the quality of life for autistic children. It can be utilized for camps, tutoring, or educational tools to help them thrive. This initiative is particularly meaningful, as several members of the legal team have personal connections to autism, underscoring their dedication to this cause.
Autism Academic Scholarship Programs

Autism Care Today Grant

AUTISM CARE TODAY
Private
United States
Unspecified amount
The Autism Care Today Grant provides vital funding assistance to families affected by Autism Spectrum Disorders across the United States. Since its inception in 2005, it has supported over 1,562 families with more than $1.85 million in grants. The program focuses on enhancing the quality of life for children with autism through various initiatives, including safety measures, assistive technologies, and behavioral therapy funding, while also addressing the unique challenges faced by military families.
Autism

Autism Care Today SOS Program

AUTISM CARE TODAY
Private
United States
Up to US $5,000
The Autism Care Today SOS Program is dedicated to providing immediate assistance to families affected by autism across the United States. Established in 2005, this program addresses urgent needs for effective treatments and services for autism spectrum disorders. Unlike typical grant cycles that may take up to 12 weeks, the SOS Program prioritizes those in critical situations, ensuring timely support based on available funding. Eligibility includes a family income below $45,000 and a demonstrated immediate need for treatment.
Autism

Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) (357667)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,250,000
The Limited Competition: Clinical and Translational Science Award (CTSA) Program's Collaborative and Innovative Acceleration Award aims to enhance translational research by fostering collaboration in developing and implementing innovative solutions. This funding opportunity invites applications focused on new approaches and technologies that will improve research impact across various diseases and expedite treatment availability. Eligible applicants include organizations with active CTSA hub prime or partnering awards.
Health & Medicine Pharmacology Biomedical informatics +4 more

Outdoor Recreation Legacy Partnership Program (ORLP) Recurring Notice 5 Year

US Department of the Interior: National Park Service (NPS)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $15,000,000
The Outdoor Recreation Legacy Partnership Program (ORLP) is a competitive grant initiative by the National Park Service, aimed at enhancing parks and recreational opportunities in urban, underserved communities. This program supports the acquisition, development, and renovation of outdoor recreation areas through federal funding, addressing the needs of community organizations, local governments, and recognized tribes. Applications are accepted twice a year, before June 1 and November 1.
Parks & Public Spaces Outdoor Recreation Outdoor Equity

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 1

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement aims to enhance methods for conducting patient-centered comparative clinical effectiveness research. This initiative seeks to address critical methodological gaps, focusing on improving the use of artificial intelligence in clinical research, study design, data research networks, and ethical protections in patient-centered CER. With a budget of up to $750,000, successful proposals will contribute to the quality and strength of evidence generated in CER studies.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 2

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is offering funding up to $750,000 for studies aimed at addressing critical methodological gaps in patient-centered comparative clinical effectiveness research. This initiative focuses on enhancing the quality of evidence in clinical research by prioritizing areas such as artificial intelligence, study design improvements, support for data research networks, and ethical considerations. Successful proposals will contribute to advancing research methodologies and improving patient outcomes.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding - Cycle 3

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.
Health & Medicine Medical Ethics Artificial Intelligence (AI)

Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Risk and Protective Factors of Family Health initiative invites research proposals to explore family health and resilience, addressing health disparities in minority communities. Key submission deadlines are set for various dates from February 2025 to February 2027. This program is supported by the National Institutes of Health, highlighting the importance of family well-being as a critical area for advancing health equity. Proposals should focus on interventions that improve family health outcomes.
Family Services Minority Services Health Disparities & Social Determinants of Health

ASTS: Veloxis Fellowship in Transplantation Grant

American Society Of Transplant Surgeons
Private
North America
US $85,000
The ASTS: Veloxis Fellowship in Transplantation Grant offers $42,500 per year for two years to support clinical training in solid organ transplantation. This grant is aimed at current transplant surgery trainees who have completed their surgical residency and are committed to the field. Awardees must attend the ASTS Award Ceremony and complete their fellowship at the same institution for the duration of the award, ensuring a focused and comprehensive training experience.
Surgery Organ And Tissue Banks

Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,900,000
The National Cancer Institute (NCI) invites applications for the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program. This funding opportunity focuses on advanced pre-clinical research aimed at developing nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards will support the maturation of innovative nanomedicines using nanoparticles and nano-devices, enhancing cancer treatment efficacy. Successful projects will progress towards further NCI translational programs, such as the NExT initiative.
Cancer / Oncology Nanomaterials & Nanotechnology

Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional) (357744)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
This funding opportunity supports exceptionally promising Early Stage Investigators in genomics, encouraging innovative research across various fields such as genomic sciences and medicine. Applicants must submit their proposals by 5:00 PM local time of their organization. The initiative, led by the US Dept. of Health & Human Services through the NIH, aims to foster long-term career development in genomic research while addressing its ethical, legal, and social implications.
Genetics & Genomics Medical Ethics

Dean John A. Knauss Marine Policy Fellowship

Woods Hole Oceanographic Institution (WHOI)
Private
American Samoa, Guam +4 more
Unspecified amount
The Dean John A. Knauss Marine Policy Fellowship offers a unique opportunity for early career professionals to engage in marine and Great Lakes science and policy within the U.S. government. This one-year, paid fellowship encourages graduate students from accredited programs to explore impactful coastal resource issues. Interested applicants should connect with their local Sea Grant program or the National Sea Grant Office for guidance, especially if they are from Massachusetts, to ensure a competitive application.
Marine Biology Marine / Ocean Conservation Environmental Policy +2 more

The Transformational Partnerships Fund: Catalytic Grants

ECMC Foundation
Private
United States
Up to US $100,000
The Transformational Partnerships Fund offers catalytic grants of up to $100,000 for colleges and universities to explore innovative partnerships. These grants aim to enhance student success by facilitating collaborations that can significantly change institutional operations. Priority is given to partnerships involving diverse student populations and those expected to yield better outcomes. This opportunity supports institutions in assessing transformative possibilities, making it an essential resource for educational advancement.
Education System Policy & Reform College Success / Persistence

The Transformational Partnerships Fund: Seed Grants

ECMC Foundation
Private
United States
Up to US $10,000
The Transformational Partnerships Fund offers Seed Grants of up to $10,000 to colleges and universities seeking to explore partnerships that can enhance their operations. These grants support events aimed at fostering collaboration among leadership and stakeholders, paving the way for transformative initiatives. Applications are reviewed on a rolling basis, encouraging institutions to engage actively in crafting sustainable solutions centered on student success.
Education System Policy & Reform College Success / Persistence

CFWM: Scholarship Program

Community Foundation of Western Massachusetts
Private
United States
Up to US $3,000
The Community Foundation of Western Massachusetts offers a Scholarship Program aimed at assisting students in Franklin, Hampden, and Hampshire counties with their college education expenses. Annually, they provide over 1,000 scholarships, totaling approximately $1.4 million. Eligible applicants include undergraduate and graduate students enrolled in accredited institutions across the U.S. Scholarships can help cover tuition, fees, and living costs, with awards up to $3,000 available for one academic year.
All fields of work

ALF: Pilot Research Awards

American Liver Foundation
Private
United States
US $50,000
The ALF: Pilot Research Awards offer funding of $50,000 for one year to early career investigators focusing on innovative research in rare liver diseases. These awards aim to support junior faculty during the pilot phase of their projects, encouraging high-risk, high-reward ideas. Proposals should present clear, testable hypotheses without the need for extensive preliminary data, ultimately aiming to generate key findings that can lead to larger NIH grants.
Liver Disease

Junior Faculty Development Award

American College Of Gastroenterology Inc
Private
Canada, United States
Up to US $450,000
The Junior Faculty Development Award, funded by the American College of Gastroenterology, offers $450,000 over three years to support junior researchers in gastroenterology or hepatology. Aimed at ACG members, this award allows recipients to dedicate 50% of their time to clinical research, enhancing their skills and advancing their careers. Eligible candidates include those within seven years post-fellowship who can guarantee protected research time. The initiative fosters novel research that directly impacts gastrointestinal health.
Digestive System Health & Diseases

Established Investigator Bridge Funding Award

American College Of Gastroenterology Inc
Private
Canada, United States
Up to US $300,000
The Established Investigator Bridge Funding Award, supported by the ACG Institute for Clinical Research and Education and the American College of Gastroenterology, offers $300,000 in funding over two years for established researchers facing funding gaps. Designed for clinical gastroenterology and hepatology, this grant aims to sustain impactful research programs during federal funding lapses. Eligible applicants must be ACG members and have at least eight years of experience post-training, along with a proven track record of federal funding in relevant fields.
Digestive System Health & Diseases

Leonidas Berry Health Equity Research Award

American College Of Gastroenterology Inc
Private
Canada, United States
Up to US $75,000
The Leonidas Berry Health Equity Research Award, presented by the ACG Institute, honors Dr. Leonidas H. Berry and supports innovative research aimed at reducing health disparities among underrepresented groups in gastrointestinal health. With a funding opportunity of $75,000 over two years, this award encourages eligible U.S. or Canadian physicians to develop impactful research careers that enhance our understanding of health equity in gastrointestinal practice. Applications are open until June 30, 2028.
Digestive System Health & Diseases

ACG/ASGE Epidemiologic Research Award in Gastrointestinal Endoscopy

American College Of Gastroenterology Inc
Private
Canada, United States
Up to US $50,000
The ACG/ASGE Epidemiologic Research Award in Gastrointestinal Endoscopy supports research projects that study the use and outcomes of gastrointestinal endoscopy through the GI Quality Improvement Consortium (GIQuIC). Co-sponsored by the American College of Gastroenterology and the American Society for Gastrointestinal Endoscopy, this award is aimed at enhancing the quality and outcomes of GI endoscopic procedures, benefiting both practitioners and patients.
Digestive System Health & Diseases

Anonymous Was A Woman Environmental Art Grants

New York Foundation for the Arts
Private
United States
Up to US $20,000
The Anonymous Was A Woman Environmental Art Grants offer up to $20,000 for environmental art projects led by women-identifying artists in the U.S. and territories. Focused on themes like regeneration and eco-social engagement, the grants encourage projects that address ecological issues through ethical engagement. For the 2025 cycle, over $520,000 will be distributed, doubling previous funding. Eligible applicants must be 18+, lead artists, and not enrolled in degree programs during the grant term.
Environmental Conservation Public / Community Art Music +14 more

South Dakota: Community Development Block Grants: Community Projects (SD)

South Dakota Governor's Office of Economic Development
State/Local Government
South Dakota
Unspecified amount
The South Dakota Community Development Block Grant (CDBG) program provides essential funding for various community development needs, including water infrastructure and workforce training. Local governments are encouraged to collaborate with planning districts to identify projects and apply for funding. The program allocates funds across three accounts: Community Projects, Special Projects, and Urgent Needs, each targeting specific community challenges. Eligible projects must align with state objectives, emphasizing economic opportunities for low- and moderate-income residents.
Community Development & Revitalization Public Infrastructure Workforce Preparation & Job Readiness

South Dakota: Community Development Block Grants: Special Projects (SD)

South Dakota Governor's Office of Economic Development
State/Local Government
South Dakota
Unspecified amount
The South Dakota Community Development Block Grant (CDBG) program supports community projects that enhance infrastructure and job opportunities for low- and moderate-income individuals. Applications for Special Projects are accepted year-round until funding is exhausted or by December 31. Local governments are encouraged to collaborate with regional planning districts to identify viable projects. With various funding accounts, the program aims to address urgent community needs and promote economic development.
Job Creation Community Development & Revitalization

McCook County Grants for Nonprofits Highlights

Looking for McCook County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all McCook County grants recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in McCook County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the McCook County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for McCook County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538