Best Mellette County Grants for Nonprofits in South Dakota

Elizabeth Ratta, a brain aneurysm survivor and a Bee Foundation ‘share your story’ contributor is passionate about spreading brain aneurysm awareness and particularly in the populations they disproportionately affect- those who are Black, Hispanic and women. This research grant is named for Elizabeth’s grandma, Rita who had an unruptured brain aneurysm, but at a time when there was limited treatment and support.About Rita Skertich GrantThe Rita Skertich Grant is specifically intended to fund research topics that focus on prevention and treatment of brain aneurysms in the Black and Hispanic population and women; the populations most affected by brain aneurysms. African Americans and Hispanics are twice as likely to have a rupture compared to white Americans. Women are more likely than men (3:2 ratio) to have a brain aneurysm and 1.5 times more at risk of rupture than men. The research funded by this grant will support efforts to improve outcomes, accessibility and a greater understanding of discrepancies in the statistics for these populations with a focus on prevention. The preference is that this grant will be given to a Black, Hispanic and/or female researcher with other underrepresented research groups also considered.Grant Funding: 

• $15,000 total amount to be distributed, but not limited to only 1 awarded applicant
• Applicants may request up to $15,000

The Focused Discovery Awards (HHF-FDA) by the Hearing Health Foundation provide up to $50,000 annually for innovative research in hearing and balance. Targeted at early career investigators, these grants aim to foster groundbreaking projects that enhance understanding and treatment of hearing loss, benefiting millions. Applicants must demonstrate a strong research background and institutional support, ensuring that funds are directed towards high-impact projects that can lead to future funding from major research institutions.

The Focused Discovery Awards - Type 2 (HHF-FDA-2) provide funding of up to $50,000 for innovative research addressing hearing and balance issues. Open to investigators at any career stage, these grants aim to support new lines of inquiry in underfunded areas of otology. The Hearing Health Foundation encourages applications that demonstrate strong research training and institutional support, fostering advancements in hearing health for millions affected by related conditions.

The Expanded Discovery Awards (HHF-EDA) by the Hearing Health Foundation provide crucial funding up to $100,000 per year for innovative research in hearing and balance. These awards support both emerging and established investigators addressing specific topics in the field. With a focus on early career researchers, HHF-EDA aims to foster groundbreaking work that can lead to significant advancements in treatment and understanding of hearing loss, benefiting millions affected by these conditions.

Governor’s Office of Economic Development

Our Mission: The Governor’s Office of Economic Development drives the economic development environment that ensures the next generation can succeed in South Dakota.

No matter what your economic development needs are in South Dakota, the Governor’s Office of Economic Development can help. We have an array of resources at our disposal – from financing to research, from networking to cutting red tape – that you can use to help your new or existing business flourish.

Workforce Development Program

The South Dakota Workforce Development Program is a commitment by the State of South Dakota to extend education and training resources so that South Dakota employers will be provided with a well-trained and skilled workforce. Through matching grants, the Workforce Development Program funds industry-education partnerships through which customized training programs and short-term, job-specific training is delivered. The Workforce Development Program supports up to one-half the total cost of training. 

How it Works

When the applicant is approved, the award is made on a reimbursement basis upon completion of the training. Awards will be paid on a per-person basis with 85% of the grant paid upon receipt of the initial report and 15% paid upon receipt of the follow-up report.

Governor’s Office of Economic Development

Our Mission: The Governor’s Office of Economic Development drives the economic development environment that ensures the next generation can succeed in South Dakota.

No matter what your economic development needs are in South Dakota, the Governor’s Office of Economic Development can help. We have an array of resources at our disposal – from financing to research, from networking to cutting red tape – that you can use to help your new or existing business flourish.

Local Infrastructure Improvement Program

Purpose

The Board of Economic Development may provide grants to assist in funding the construction or reconstruction of infrastructure for the purpose of serving economic development projects.

Helping Infrastructure Support Investment

The Local Infrastructure Improvement Program provides grants to local development corporations, tribal governments, municipalities, counties, or other political subdivisions to construct or reconstruct public infrastructure associated with an economic development project.

How it Works

Applicants must identify an economic development project and then work with their area planning district to submit a completed application before funding is considered.

If the board approves the application, the applicant must comply with the conditions of approval to remain eligible for the grant. GOED will issue payment within 30 days of receiving the required compliance documentation.

The BJA FY 2026 Missing and Unidentified Human Remains (MUHR) Program aims to enhance public safety by improving the processes for reporting, transporting, and identifying missing persons and unidentified human remains. This funding opportunity supports efforts to locate missing individuals and address cases involving migrants, as authorized by Public Law 116-277. The program is part of the Office of Justice Programs' commitment to uphold justice and protect the rights of American citizens.

The Advancing State Implementation of the National Strategy to Support Family Caregivers grant aims to support state-level projects that align with the 2022 National Strategy to Support Family Caregivers. Grantees will form cross-agency partnerships to implement the Strategy's recommendations, focusing on sustainability through planning phases. The initiative encourages innovative solutions to enhance caregiver support while ensuring that project outcomes are maintained beyond federal funding.

The National Adult Protective Services Training Center (NATC) aims to enhance the skills of adult protective services professionals. By providing a cooperative agreement, the NATC will develop online learning modules through a web-based management system, focusing on evidence-informed practices and leadership development. This initiative seeks to improve the organizational climate of APS agencies and ensure better safety and well-being for individuals facing adult maltreatment.

The FY2027 Grants to Highest State Courts aim to enhance guardianship systems by evaluating and improving the fairness and effectiveness of adult guardianship proceedings. This initiative, funded by the US HHS Administration for Community Living, seeks to implement necessary changes based on assessments, streamline filing processes, and better detect fraud, ultimately ensuring the safety and integrity of protected individuals.

The National Center on Elder Abuse Resource Center aims to enhance the readiness of communities to combat elder abuse, neglect, and exploitation. By offering resources, training, and information, the center empowers professionals and the public to effectively prevent and respond to elder maltreatment, ensuring that older Americans can live with dignity and independence. This initiative, supported by the US HHS Administration for Community Living, emphasizes best practices and awareness to mitigate risks associated with elder fraud and scams.

About PLTW Computer SciencePLTW Computer Science students are technology trailblazers who are empowered through transportable skills and prepared to start their career, whether that is in computer science or not.

Lockheed Martin has committed funds to support PLTW grants to schools interested in adding PLTW.

Since 2007, Lockheed Martin has partnered with PLTW to address the nation's critical need for future engineers, computer scientists, and math- and science-trained professionals, and to equip all students with the knowledge and skills they need to thrive. Lockheed Martin supports PLTW programs in school districts across the nation and has contributed to the development of PLTW's middle school and high school courses focused on aerospace engineering and flight. Since the first school district partnership in 2014, over 855 PLTW programs have been implemented and more than 145,328 students have gained access to PLTW.Program Requirements:

• Grantee must use their grant funds to expand their existing PLTW Computer Science program.
  • Example expansion activities include but are not limited to adding an additional PLTW Computer Science course not previously offered,
  • and/or adding additional class periods of an existing PLTW Computer Science courses previously offered,
  • and/or training additional teachers in PLTW Computer Science courses for the 2027-2028 academic year. 

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

About PLTW Computer SciencePLTW Computer Science students are technology trailblazers who are empowered through transportable skills and prepared to start their career, whether that is in computer science or not.

Lockheed Martin has committed funds to support PLTW grants to schools interested in adding PLTW.Since 2007, Lockheed Martin has partnered with PLTW to address the nation's critical need for future engineers, computer scientists, and math- and science-trained professionals, and to equip all students with the knowledge and skills they need to thrive. Lockheed Martin supports PLTW programs in school districts across the nation and has contributed to the development of PLTW's middle school and high school courses focused on aerospace engineering and flight. Since the first school district partnership in 2014, over 855 PLTW programs have been implemented and more than 145,328 students have gained access to PLTW.Program Requirements:

• Grantee must offer at least one PLTW Computer Science course in the 2027-2028 academic year.
• Grantee may implement any PLTW Computer Science course of their choosing

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

The scholarships and fellowships provide recipients with the opportunity to attend and explore the operation of the field at the NRPA Annual Conference. A primary focus is to inspire future participation and leadership in NRPA and to develop professional contacts with leadership and members from around the nation. Recipients receive complimentary NRPA Annual Conference registration and a travel stipend.

Young Professional Fellowships

The fellowship provides selected young professionals (up to 4) with the opportunity to explore the operation of NRPA and its governing bodies at the NRPA Annual Conference through the support of Sourcewell. Participants will meet with mentors, be recognized at the awards ceremony and attend various conference sessions and meetings. A primary focus of the program is to inspire future participation and leadership in NRPA and to develop professional contacts.

About The Glaucoma Foundation

The Glaucoma Foundation is dedicated to improving the lives of people with glaucoma. The Foundation works to encourage and support basic and applied research in glaucoma with a goal of preserving and restoring vision. We strive to be an important resource to help patients, their families, and at-risk individuals to manage their glaucoma through education and outreach.

About Research to Prevent Blindness

The mission of Research to Prevent Blindness (RPB) is to preserve and restore vision by supporting research to develop treatments, preventives and cures for all conditions that damage and destroy sight. Since it was founded 60 years ago, in 1960, RPB has channeled more than $383 million into eye research. As a result, RPB has been identified with nearly every major breakthrough in vision research in that time.

The Glaucoma Foundation (TGF) and Research to Prevent Blindness (RPB) partner annually to provide a grant aimed at supporting women and under-represented racial and ethnic minority researchers in the pursuit of glaucoma research.

The TGF (sponsored by Patricia Hill) / RPB Fellowships in Glaucoma provide one-year $10,000 fellowships focused on substantive glaucoma research, including investigation into the etiology, diagnosis and/or treatment of glaucoma, to current ophthalmology fellows with an MD, MD/PhD, PhD or other relevant degree.

The Glaucoma Foundation: Advancing the Treatment of Glaucoma

The Glaucoma Foundation (TGF) is dedicated to accelerating breakthrough glaucoma research and helping move promising discoveries toward patients. By supporting innovative, next-generation research and connecting leading scientists and clinicians, TGF drives progress toward better understanding, diagnosis, and treatment of glaucoma, with the ultimate goal of finding a cure.

Exfoliation Syndrome and Exfoliation Glaucoma, Pressure Independent Mechanisms of Glaucoma, Neuroprotection, and the Genetics of Glaucomas that affect people under the age of 40

The Glaucoma Foundation offers grants to researchers striving to improve the lives of glaucoma patients through novel innovations and scientific advances. The areas of current focus for TGF’s Grant Research program are Exfoliation Syndrome and Exfoliation Glaucoma, Pressure Independent Mechanisms of Glaucoma, Neuroprotection, and Genetics of Glaucomas that affect people under the age of 40 years. Examples of research that may be considered range from basic science to clinical interventions, such as genetics and genomic medicine, disease modeling, assessment of ocular perfusion, artificial intelligence, and clinical research. A priority will be given to novel proposals with a viable study hypothesis leading to impactful results that are fundable at the NIH level. Initial grant funding for one year is for up to $75,000; a grantee is permitted to apply for a grant renewal of up to $75,000. A renewal grant is a one-year grant based on research findings from the initial research.

About

Raptor Research Foundation

The Raptor Research Foundation (RRF) is the world’s largest professional society for raptor researchers and conservationists. Founded in 1966 as a non-profit organization, our primary goal is the accumulation and dissemination of scientific information about raptors. The Foundation organizes annual scientific conferences and provides competitive grants and awards for researchers and conservationists. The Foundation also provides support and networking opportunities for students and early career raptor researchers.

Tom Cade Conservation Award

The Award:

The Tom Cade Conservation Award is the Raptor Research Foundation’s premiere conservation award. This non-monetary award recognizes an individual who has made significant advances in or exceptional contributions to the conservation of raptors. The award’s scope includes all aspects of conservation science and practice pertaining to raptors, including: implementing population restoration programs; advances in captive propagation and reintroduction techniques; identifying conservation biology problems and solutions; raptor biodiversity studies; and studies of rare, threatened, and endangered species. Nominations will open in the spring. Recipients will be announced at the annual meeting.

About Tom Cade:

Tom Cade was an icon and hero to us all. His passion for falcons knew no bounds. One of the founders of the Raptor Research Foundation, he was the driving force behind the reintroduction of the Peregrine Falcon east of the Mississippi and across much of its North American range. The Peregrine Fund, which he created with the recovery of a single endangered species—the Peregrine Falcon—as its goal, has grown into a conservation organization with a worldwide reach and global impact. 

About

Raptor Research Foundation

The Raptor Research Foundation (RRF) is the world’s largest professional society for raptor researchers and conservationists. Founded in 1966 as a non-profit organization, our primary goal is the accumulation and dissemination of scientific information about raptors. The Foundation organizes annual scientific conferences and provides competitive grants and awards for researchers and conservationists. The Foundation also provides support and networking opportunities for students and early career raptor researchers.

Early-career Raptor Researcher Travel Grants

The Award:

The selection committee must receive all application materials by the deadline for regular abstracts. That date is included in the announcement of RRF’s annual meeting sent each year to the membership.

• $700.
• The award will also include a free 1-year membership to RRF. 

up to three.

The FY 2027-2028 NESDIS Broad Agency Announcement (BAA) invites innovative research, education, and outreach projects that support NOAA's mission without directly benefiting the agency. With funding contingent on appropriations, applicants are notified that funds are not yet available. This announcement also emphasizes the importance of environmental and cultural resource stewardship, enabling informed decision-making for public lands and trust resources, while ensuring NOAA remains responsive to changes in our natural systems.

The Notice of Intent to Issue NOFO DE-FOA-0003649 aims to leverage domestic infrastructure to enhance the production of alternative chemicals, fuels, and feedstocks. This initiative by the DOE encourages innovative technologies that utilize existing biomass resources, aiming to advance energy innovation and expand energy production. The potential NOFO will support the creation of stable liquid products from biomass, establish pilot sites for hydrogen-natural gas blending, and promote the production of market-competitive commodity chemicals.

This funding opportunity invites applications for Testing Centers focused on evaluating somatic cell genome editing technologies for translational applications. These centers will provide essential resources and testing services to researchers, ensuring the efficacy and safety of novel genome editing methods. By developing innovative in vivo and in vitro models, the centers aim to enhance scientific rigor and reproducibility in biomedical research, ultimately supporting the advancement of therapeutics for human diseases.

The National Institute on Aging intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Coordinating Center (CC) of the Claude D. Pepper Older Americans Independence Centers (OAIC) program. The CC serves as a facilitator for OAIC site interactions and as a conduit for translating OAIC objectives and findings to both scientific and general audiences. The proposed CC must demonstrate an ability to work cooperatively with all OAIC sites and possess sufficient scientific expertise in geriatrics and related areas to serve the national coordination functions of the OAIC program. Applicants should have a demonstrated ability to coordinate multi-site projects.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.

Merck Foundation

The Merck Foundation is dedicated to advancing access to health by supporting innovative programs and partnerships to improve the health and well-being of people around the world.

Helping build stronger health systems and address barriers to high-quality care

Through our programs, we believe that by working closely with governments, donors, patient groups, healthcare professionals, nonprofit organizations, academic institutions, multilateral agencies, the private sector and others, we can help build stronger health systems that provide better care.

Community Collaborative for Reimagining HIV Care: Call for Proposals

Overview

The Merck Foundation (the “Foundation”) is pleased to announce the launch of the Community Collaborative for Reimagining HIV Care (the “Collaborative”), a five-year national initiative to improve timely access to and continuity of high-quality, person-centered care for people living with HIV in under-resourced communities across the United States.

Through this Call for Proposals, the Foundation will select eligible organizations to implement innovative, community-centered programs that address the evolving needs of people living with HIV.

The Foundation for Physical Therapy Research offers the Promotion of Doctoral Studies Scholarships for doctoral candidates, providing up to $15,000 annually. This scholarship supports students who have completed their coursework and exams, aiming to foster impactful research careers in physical therapy. Applicants may receive a total of $30,000 during their candidacy phase, with a maximum of $45,000 throughout their doctoral program. This initiative prioritizes academic excellence and alignment with APTA research priorities.

This project aims to develop a robust method for correcting solution chemistry interferences in electrochemical sensor measurements of complex environmental water matrices. By employing a ratiometric comparison approach, it seeks to enhance the detection of harmful contaminants like PFAS in drinking water. This initiative aligns with the priority of safeguarding public health through early detection and informed decision-making, ultimately ensuring access to safe, clean drinking water for communities.

The National Institute of Allergy and Infectious Diseases (NIAID) aims to enhance its mission through the Implementation and Evaluation of Databases to Examine AIDS Consortium. This initiative merges clinical, genomic, and epidemiologic data to foster evidence-based research and implementation science. By leveraging advanced data science and AI technologies, the consortium addresses HIV morbidity and mortality, improving prevention and treatment strategies. This work aligns with the U.S. Ending the HIV Epidemic initiative, ensuring impactful contributions to public health.

The OJP FY 2026 Integrity in American Elections Grant Program aims to enhance election integrity across the United States. This initiative, supported by the US Department of Justice, focuses on empowering state and local prosecutors to effectively prevent and prosecute voter fraud and maintain the integrity of voter rolls. By safeguarding elections against illegal voting and registration practices, this program is vital for upholding public confidence in democratic processes and ensuring that every American's vote counts.