Best Unrestricted Grants for Nonprofits in Michigan

The Prince Hall Award, managed by the Albion Community Foundation, is designed to foster youth leadership, character, and moral development in the greater Albion area. This grant supports local nonprofits and institutions with a maximum request of $150. Eligibility extends to 501(c)(3) organizations and faith-based entities serving the community. Since its inception, the foundation has distributed over $3.7 million to advance community improvement, cultural heritage, and youth development.

The Jack Hoaglin Family Fund, managed by the Albion Community Foundation, supports math and science education specifically for girls in the Albion area, alongside early childhood education initiatives. Eligible applicants include 501(c)(3) nonprofits and faith institutions within the community. Grants up to $450 are available, fostering educational growth and empowerment. The foundation prioritizes community improvement and development, having granted over $3.7 million to various causes since its inception.

The Boggan/Holland African American Community Fund, established by the Albion Community Foundation, aims to empower African American youth through targeted programs. Grants up to $1,000 support initiatives that enhance community engagement and cultural heritage. Eligibility extends to 501(c)(3) nonprofits within the greater Albion area, including faith institutions and schools. The fund prioritizes projects that directly benefit the African American community, fostering growth and development while ensuring applicants are in good standing with previous grants.

The America’s Horse Cares Grant Program, provided by the American Quarter Horse Association, aims to enhance the welfare and training of American Quarter Horses in therapeutic settings. By funding educational workshops from March to September 2026, the program seeks to elevate horsemanship standards and ensure proper horse care. Organizations eligible for funding must be 501(c)(3) tax-exempt, focusing on equine-assisted activities for individuals with various challenges, thereby fostering transformative experiences through education and responsible practices.

The Engagement Award: Convening Support fosters meaningful collaboration among patients, caregivers, clinicians, and other stakeholders in research. Initiated by the Patient-Centered Outcomes Research Institute (PCORI), this program aims to enhance patient engagement throughout the research process. By providing tools and resources, the award supports initiatives that improve healthcare delivery and outcomes, ensuring that patient perspectives are integral to research efforts.

Evidence Based Safety Contextualization of JAK inhibitors in the Treatment of Moderate to Severe Atopic Dermatitis

Primary Area of Interest:

Dermatology – Atopic Dermatitis

General Area of Interest for this RFP:

Potential applicants should describe their initiative to synthesize the existing medical literature on the safety data available for JAKis indicated for the treatment of M2S AD and distill it into a concise, practical communication for the community of providers who treat AD. The educational initiative should be based on the body of scientific evidence available in the literature including the following, but not limited to:

• Retrospective, cohort analyses evaluating the background risk of adverse events of special interest (infections, cardiovascular events, malignancies etc.) in patients diagnosed with M2S AD.
• Clinical trial safety data for use of JAKis for the treatment of M2S AD, including assessments of subpopulations (i.e. adolescents, elderly; cardiovascular risk factors etc.).
• Observational analyses, network meta-analyses, or other safety analyses, including comparative safety analyses and/or real-world assessments to examine the rate of adverse events of special interest in patients receiving JAKis for treatment of AD.

Funding Range and Project Length

Individual projects requesting up to $75,000 USD will be considered. Maximum project length is 1 year.

This grant opportunity invites applications for Large Health Services Research Demonstration and Dissemination Projects aimed at combating antibiotic-resistant bacteria (CARB). The projects should focus on promoting the appropriate use of antibiotics, minimizing the transmission of resistant bacteria, and preventing healthcare-associated infections (HAIs). Applications must be submitted by 5:00 PM local time of the applicant organization, as specified in the announcement.

This grant opportunity supports large-scale research projects aimed at combating antibiotic-resistant bacteria (CARB). It focuses on promoting the appropriate use of antibiotics, reducing the transmission of resistant strains, and preventing healthcare-associated infections (HAIs). Funded by the US Department of Health and Human Services' Agency for Healthcare Research and Quality (AHRQ), this initiative encourages innovative approaches to address these critical public health challenges.

The New Music Organization Fund Grant supports non-profit organizations and performance groups dedicated to promoting new music and nurturing creators. This grant prioritizes artistic merit, community impact, immediate funding needs, and a commitment to inclusion. Eligible entities can apply for assistance to sustain their vital programming and resources for artists, ensuring the continued development of a vibrant music community.

The Terry Farrell Firefighters’ Fund, established post-9/11, provides vital educational and financial support to families of firefighters across the U.S. With over $10 million distributed in grants and surplus gear, the fund offers scholarships, emergency assistance, and training for first responders. It also supplies rural fire departments with necessary equipment and sponsors health initiatives like blood and bone marrow drives, ensuring comprehensive support for those who serve our communities.

Kappa Alpha Psi Foundation Scholarships

The Foundation Scholarships are merit-based and awarded to qualified students with a consideration of financial need. All recipients shall be in pursuit of a baccalaureate degree from an accredited college or university and as described by the respective scholarship criteria. Most scholarships are for one year, non-renewable unless otherwise indicated in the award description. 

The Libraries Transforming Communities: Accessible Small and Rural Libraries' Grant, initiated by the American Library Association (ALA), aims to enhance accessibility and community engagement in small and rural libraries serving people with disabilities. With funding up to $20,000, selected libraries will receive support for projects that improve library services and facilities. This initiative promotes collaboration with community members to identify and address accessibility needs, ensuring libraries effectively serve diverse populations.

The Vince Lombardi Cancer Foundation (VLCF) has played a pivotal role in cancer research and education since its inception in 1971, raising over $21 million to support innovative treatments and compassionate care. This private foundation invites applications from recognized healthcare institutions, focusing on funding scientific and medical fellowships. VLCF is dedicated to preventing cancer and improving patient care, ensuring that the spirit of excellence continues in the fight against this disease.

The Trauma Care Readiness and Coordination Cooperative Agreement aims to enhance trauma system resilience, aligning with ASPR's vision for a prepared nation in the face of disasters and public health emergencies. This program supports innovative and scalable trauma system models, ensuring communities are equipped with robust healthcare responses. By fostering collaboration and effective planning, it seeks to protect lives and reinforce national security through well-coordinated trauma care strategies.

The Mark Foundation Emerging Leader Award supports innovative cancer research led by early career investigators. Aimed at high-impact, high-risk projects, this grant is available to those employed by U.S. or Canadian non-profit academic institutions. Eligible applicants must be within three to eight years of starting their independent faculty research appointment. This award emphasizes multi-year independent funding and is not intended as the main funding source for the laboratory, ensuring that diverse research efforts are encouraged.

The Youth Programming Grant, offered by the Native American Agriculture Fund (NAAF), aims to support Native American farmers and ranchers through various projects. This grant focuses on providing essential business assistance, agricultural education, and advocacy services. By funding diverse initiatives, the NAAF seeks to promote the ongoing involvement of Native communities in agriculture, ensuring their sustainable growth and development within the sector.

The Investigators in the Pathogenesis of Infectious Disease Grant Program, funded by the Burroughs Wellcome Fund, aims to support early-career assistant professors studying human infectious diseases. With a budget of $505,000 over five years, it encourages innovative research on the interplay between human systems and infectious agents, fostering multidisciplinary approaches to enhance our understanding of disease mechanisms and health maintenance.

The Republic Services Community Grant Program supports local nonprofit organizations focused on neighborhood revitalization, safety, disaster relief, and social services. Eligible 501(c)(3) organizations can apply once annually through an online application process. The program emphasizes a non-discrimination policy, ensuring services are provided without bias. However, funding is not available for individuals, government entities, schools, or religious organizations. This initiative reflects Republic Services' commitment to community engagement and support.

The Petco Foundation offers disaster relief support for animal welfare organizations affected by disasters. Eligible applicants include authorized members of IRS-designated 501c3 nonprofits, government agency representatives with operational insight, and invited for-profit entities focused on animal welfare. However, the foundation does not fund individuals, organizations outside the U.S., or those whose primary mission does not relate to animal welfare. This initiative aims to provide critical assistance during times of crisis.

The Rauschenberg Medical Emergency Grants, administered by the New York Foundation for the Arts, provide one-time funding up to $5,000 for artists facing unexpected medical emergencies. This program aims to alleviate financial burdens caused by medical costs, ensuring that artists can receive necessary care without delay. Eligible applicants must be practicing artists in visual arts, film, or choreography, and demonstrate financial need. This initiative supports artists of color, LGBTQ+ individuals, and those outside major coastal cities.

The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.

The AFAR Grants for Junior Faculty and Glenn Foundation for Medical Research offer up to $160,000 for one- to two-year research projects focusing on the biology of aging. Aimed at early career faculty, these grants support innovative studies not limited to age-related diseases but rather the fundamental mechanisms of aging. Approximately 10 grants will be awarded in 2026, with funding starting July 1. Applicants must be independent investigators within 10 years of their postdoctoral training.

The McKnight Endowment Fund for Neuroscience offers Scholar Awards to early-career neuroscientists focusing on learning and memory disorders. The awards provide up to $225,000 over three years, emphasizing research that could lead to significant clinical advancements. Eligible candidates must work as independent investigators at U.S. non-profit institutions, hold an Assistant Professor position for less than four years, and demonstrate their research program's potential. The program aims to foster innovative solutions in neuroscience.

The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.

The Myelodysplastic Syndromes (MDS) Research Fund Grant, established by the Vera and Joseph Dresner Foundation, aims to enhance research and treatment of MDS and related blood disorders. This fund supports innovative projects addressing etiology, biology, genetics, prognosis, treatment, symptom management, and quality of life. It offers up to $125,000 for Early Career Awards and $250,000 for Established Investigator Awards, facilitating significant advancements in the field.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

The Placement and Coordination Program, administered by the Office of Refugee Resettlement, invites eligible organizations to enhance refugee resettlement services. By diversifying service providers, the program aims to strengthen the national resettlement framework. Key responsibilities include managing the Program of Initial Resettlement and Intensive Case Management for vulnerable refugees, ensuring comprehensive support from arrival through initial resettlement, and addressing barriers to self-sufficiency.