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Best Middlesex County Grants for Nonprofits in Connecticut

Looking for grants for 501(c)(3) nonprofit organizations working in Middlesex County, Connecticut? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,361 Results based on applied filters

Discovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Gabriella Miller Kids First Pediatric Research Program invites applications for whole genome sequencing of pediatric cohorts. This initiative aims to explore the genetic basis of childhood cancers and congenital anomalies, enhancing our understanding of their etiology. Researchers are encouraged to propose sequencing methods, including whole genome and exome sequencing, to investigate genetic contributions and associations with cancer risk. The resulting data will be integrated into the Kids First Data Resource for broader research collaboration.
Children’s Health & Pediatrics Genetic Conditions & Birth Defects Pediatric Cancers

Restoring Joint Health and Function to Reduce Pain (RE-JOIN) 2.0

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a Notice of Funding Opportunity (NOFO) under the NIH HEAL initiative to enhance research on joint health and pain. This initiative aims to refine the understanding of joint tissues and pain mechanisms, expand clinical phenotyping, and support preclinical testing of novel therapies. Collaborations among experts in neurobiology, pain science, and rheumatic diseases are encouraged to foster innovative solutions for joint pain management.
Musculoskeletal Diseases Arthritis

Genomic Community Resources (U24 Clinical Trials Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Human Genome Research Institute (NHGRI) is launching a Notice of Funding Opportunity (NOFO) aimed at enhancing genomic research through the development and distribution of high-value resources. This initiative encourages collaborative efforts in genomic resource development and the integration of data science in clinical applications. While applications are not currently being accepted, prospective applicants are urged to prepare meaningful collaborations and projects ahead of the formal solicitation.
Cancer / Oncology Genetics & Genomics Human Genome & Genetics

Medical Scientist Training Program (MSTP)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Medical Scientist Training Program (MSTP) aims to cultivate skilled clinician-scientist leaders to meet the nation's biomedical research demands. It supports domestic organizations in developing dual-degree training that integrates clinical and research education, leading to both a clinical degree (e.g., M.D., D.O.) and a Ph.D. Through comprehensive mentoring and career development, MSTP prepares trainees for impactful careers in health-related research, ensuring a robust pipeline of qualified scientists.
Science Medical Education & Professional Training

Native American Research Centers for Health (NARCH)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Unspecified amount
The Native American Research Centers for Health (NARCH) program supports federally-recognized American Indian and Alaska Native Tribes and organizations in advancing health-related research. It aims to enhance research careers and infrastructure through a competitive application process. Funded by the US Dept. of Health & Human Services, this initiative invites eligible entities to apply, ensuring that only high-quality proposals undergo peer review for potential funding.
Native American Services Native American Culture & Heritage Indigenous Services

Network of the National Library of Medicine Regional Medical Libraries (UG4 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $600,000
The National Library of Medicine (NLM) is seeking applications to establish Regional Medical Libraries within the Network of the National Library of Medicine (NNLM). Since 1965, the NNLM has enhanced public health information access through partnerships with libraries and health organizations. The initiative aims to improve community engagement, disseminate NIH research findings, and foster collaborations to promote health literacy and access to biomedical data, thereby supporting local clinical research efforts.
Health & Medicine Library & Information Science Library Services

Network of the National Library of Medicine Training Center (U24 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The National Library of Medicine (NLM) is seeking applications for a Training Center under the Network of the National Library of Medicine (NNLM). This initiative aims to enhance professional development for librarians, community engagement, and access to health information. By fostering partnerships and disseminating NIH resources, the NNLM will broaden its impact and improve public understanding of health data and information. The NTC will develop innovative training curricula and materials to meet diverse audience needs.
Health & Medicine Library & Information Science Library Services

Network of the National Library of Medicine Coordinating Center (U24 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $1,500,000
The National Library of Medicine (NLM) is inviting applications for its Coordinating Center within the Network of the National Library of Medicine (NNLM). Established in 1965, the NNLM enhances public access to health information through collaboration with libraries and community organizations. The NCC will oversee network administration and evaluation, fostering partnerships and supporting local clinical research. This initiative aims to expand NIH engagement and improve public understanding of health resources and information available through the NNLM.
Health & Medicine Library & Information Science Library Services

HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $800,000
The HEAL Initiative Whole Joint Health Program aims to advance research on the biological mechanisms of joint pain by exploring the interactions of various tissues within the joint. This innovative program will support clinical studies that focus on non-pharmacological interventions to enhance healing and improve quality of life for individuals suffering from chronic joint pain. By fostering a comprehensive understanding of joint health, the initiative aligns with the NIH's broader goals to reduce chronic pain and opioid dependency.
Musculoskeletal Diseases Orthopedics

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Limited Competition Small Grant Program for the NCATS CTSA Program aims to empower KL2 scholars by funding diverse clinical and translational research projects. These grants support short-term studies, methodology development, and preliminary data collection, facilitating the transition to independent research careers. Applications will undergo NIH peer review, ensuring only high-quality proposals receive funding. This initiative fosters innovation in research methodologies and technology, ultimately enhancing the capabilities of emerging translational scientists.
Science Biology Health & Medicine +2 more

Collaborative Program Grant for Multidisciplinary Teams

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Collaborative Program Grant for Multidisciplinary Teams, funded by the US Dept. of Health & Human Services: National Institutes of Health (NIH), supports integrated teams of researchers tackling ambitious projects that individual efforts cannot achieve. This program promotes collaboration among experts with complementary skills, aiming for significant advancements in their fields. Teams are encouraged to pursue innovative objectives that have the potential to transform research landscapes.
Science Biology Health & Medicine

RAK Education Foundation Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The RAK Education Foundation Scholarship provides financial assistance to residents of Camden, Chowan, Gates, Pasquotank, or Perquimans Counties who have earned a high school diploma or GED. This scholarship supports students pursuing degrees or certificates in Career and Technical Education fields such as trade education, computer science, business, health science, and more. Applications open on December 16, 2025, and close on March 3, 2026, encouraging eligible students to apply.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Robert E. Barnhill, Sr. Scholarship Fund

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Robert E. Barnhill, Sr. Scholarship Fund provides financial support for North Carolina high school seniors who plan to attend a four-year college or university as full-time students. Eligible applicants are evaluated on leadership potential, community involvement, academic achievement, and financial need. The scholarship may be renewed for up to three additional years, contingent upon maintaining a 2.0 GPA and continuous enrollment. Applications open on December 16, 2025, and close on March 3, 2026.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Ruby A. Trivette Ruritan Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Ruby A. Trivette Ruritan Scholarship, administered by the North Carolina Community Foundation, supports graduating seniors from Ashe and Watauga counties in North Carolina. Eligible applicants must reside in Todd or be active members or children of active members of the Todd Ruritan Club. This scholarship opens for applications on December 16, 2025, and closes on March 3, 2026, providing crucial financial assistance for students pursuing higher education.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Sammy and Shirley Church Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Sammy and Shirley Church Scholarship supports students from Ashe County, NC, including those graduating from the NC School of Science and Math. Eligible candidates must demonstrate academic excellence, physical vigor, and leadership in various activities. Financial need is considered but not the only criterion. Applications open on Dec. 16, 2025, and close on March 3, 2026. Ensure to meet specific eligibility requirements set by the donor for successful application.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

The Bertha Sawyer Meiggs & Winfred B. Meiggs Sr. Family Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Bertha Sawyer Meiggs & Winfred B. Meiggs Sr. Family Scholarship supports graduating seniors from Camden, Gates, Pasquotank, and Perquimans counties, with a preference for Camden County residents. Eligible candidates must demonstrate strong academic performance, leadership skills, and community involvement while enrolling full-time in a two- or four-year college. The scholarship may be renewed at the discretion of the Scholarship Committee, subject to academic criteria and available funds.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Daniel Arnold Memorial Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Daniel Arnold Memorial Scholarship

Established in memory of Daniel Arnold, killed in action in Iraq in September, 2005. Provides a college scholarship for a student who has excelled in athletics and has exhibited patriotism for the United States.

Education - Higher Education

Gil Depew Memorial Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Gil Depew Memorial Scholarship

Established by the family of Mr. Depew to provide a college scholarship for a diabetic student from one of the six Susquehanna County high schools.

Education - Higher Education

Lawrence & Phyllis DeWolfe Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Lawrence & Phyllis DeWolfe Scholarship

Established by the family and friends of Mr. and Mrs. Lawrence DeWolfe to provide college scholarships to graduating seniors from Blue Ridge, Lackawanna Trail, and Mountain View school districts who will major in agriculture, education, a STEM field or law enforcement.

Education - Higher Education Police & Law Enforcement STEM / STEAM Education +1 more

Thomas Conaty Memorial Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Thomas Conaty Memorial Scholarship

Established by the family of Mr. Conaty to provide a college or post-secondary degree program scholarship to a student from Blue Ridge, Elk Lake or Montrose Area School Districts, including home schooled students from those districts. Preference will be given to a student who will pursue a degree in business or a related field.

Education - Higher Education Vocational & Trade Education

Robert and Diane Turrell Family Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Robert and Diane Turrell Family Scholarship

Established by Robert and Diane Hill Turrell. Provides a post-secondary scholarship to a high school graduate who is a student of good moral character and who demonstrates financial need through their Student Aid Report. Students from Lackawanna Trail, Tunkhannock, Elk Lake, Homeschooled and Wyalusing Valley High Schools may apply. Priority will be given to students living in Habitat for Humanity Housing. The recipient may re-apply during each of the remaining years of undergraduate study until reaching the age of 25.

Education - Higher Education

Scholarships for Careers Endowment

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount
The Scholarships for Careers Endowment, established by a local family in connection with the Community Foundation of the Endless Mountains, aims to support graduates of Elk Lake School District and the Susquehanna County Career & Technology Center. This scholarship prioritizes students with financial need and promise for future success, assisting them in pursuing vocational, technical, academic, or other post-secondary programs. Additionally, it contributes to special projects within the school district and community.
Education - Higher Education Vocational & Trade Education

Fred and Betty Worsh Scholarship Fund

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Fred and Betty Worsh Scholarship Fund, managed by the North Carolina Community Foundation, offers financial support to residents of New Hanover and Brunswick Counties who are U.S. citizens attending accredited four-year colleges or universities. Scholarships are available to undergraduates, graduates, and adult re-entry students, and may be renewed annually based on academic performance and financial need. Applications open on December 16, 2025, and close on March 3, 2026.
Education - High School Academic Scholarship Programs STEM / STEAM Education

Grayce Wills MacDonald and Ivan A. MacDonald Endowment

North Carolina Community Foundation Inc
Private
United States
More than US $1,000

Scholarships

We partner with donors to administer scholarships for students across the state. Most NCCF scholarships open for applications on Dec. 16, 2025, and close on March 3, 2026.

Undergraduates, graduates, medical and professional school students and adult re-entry students who are attending community colleges, four-year universities, career/technical schools, teaching credential programs and graduate, medical or professional schools in the United States are eligible for scholarships offered at NCCF.

Each scholarship has specific eligibility requirements defined by the donor when the scholarship was established. Be sure to read the requirements of each scholarship carefully as directed through the universal application and address those elements as needed in your application.

Grayce Wills MacDonald and Ivan A. MacDonald Endowment

Shall support students who attended high school in Cherokee, Graham, Clay, Swain, Macon, Jackson, Haywood, Buncombe, and Henderson counties, and who are pursuing a college or post-graduate level degree in the field of nutrition with emphasis on the study of natural foods and the vegetarian lifestyle. Scholarships may be based on both need and merit.

Education - Higher Education Education - High School Academic Scholarship Programs +2 more

JADE Learning Electrical Technologies Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The JADE Learning Electrical Technologies Scholarship supports students enrolled in North Carolina technical or occupational schools focused on electrical systems technologies. Eligible candidates include undergraduates, graduates, and apprentices who demonstrate financial need and strong academic performance. The scholarship application requires careful attention to specific donor-defined eligibility criteria. Applications open on December 16, 2025, and close on March 3, 2026, with preference given to those pursuing a two-year associate’s degree.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Joyce Price Johnson’s Samaritan Fund

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Joyce Price Johnson’s Samaritan Fund provides scholarships for young people in North Carolina who are exiting foster care or facing poverty. Eligible candidates include undergraduates, graduates, and adult re-entry students attending various accredited institutions. Applications for NCCF scholarships open on December 16, 2025, and close on March 3, 2026. Preference is given to applicants from Wayne County and adjacent areas, ensuring support for those with exceptional financial need.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Long Island Sound Community Impact Fund

Restore America’s Estuaries
Corporate
Connecticut, New York
US $5,000 - US $100,000

Long Island Sound Community Impact Fund 2026 RFA

About the Long Island Sound Community Impact Fund (LISCIF)

The Long Island Sound Community Impact Fund (LISCIF) is a partnership among Restore America’s Estuaries, the U.S. Environmental Protection Agency, and the Long Island Sound Partnership. The purpose of LISCIF is to provide technical and financial assistance to communities for addressing environmental issues and to improve the quality and accessibility of the Long Island Sound. Technical assistance will be provided through LISCIF and is available to communities/organizations even if one does not submit a proposal for funding.  

This is the third round of LISCIF funding. Up to $1,200,000 in competitive funding will be awarded to support projects in New York and Connecticut. Project proposals must incorporate Actions of the Comprehensive Conservation and Management Plan (CCMP).  

For LISCIF, the geographic region refers to the Long Island Sound watershed area within New York and Connecticut.

Funding Priorities

LISCIF’s funding priorities are aligned with the CCMP themes and Actions. For 2026, LISCIF’s main funding themes are:

  • Clean Waters and Healthy Watersheds  
  • Thriving Habitats and Abundant Wildlife  
  • Sustainable and Resilient Communities   
  • Informed and Engaged Public  

The Long Island Sound Community Impact Fund aims to build capacity for organizations located in communities affected by environmental and human health risks. The Fund seeks to provide technical assistance for communities and support proposals which ultimately improve access to the Long Island Sound, while reducing overall environmental health risks. Eligible projects and activities will be community-driven and address one of the funding priorities below:   

Funding is available for:   

  • Projects that result in quantifiable pollutant prevention or reduction.   
  • Restoring habitat within the Important Coastal Habitat Types targeted by LIS Partnership.  
  • Projects that foster a diverse balance and abundant populations of fish, birds, and wildlife.    
  • Public engagement, knowledge, and stewardship.  
  • Projects that enhance community resilience and sustainability.   
  • Planning and design that set-the-stage for implementation of water quality projects, eligible habitat restoration projects and resilience projects.   
  • Community-based science projects.  
  • Data management and integration projects.   
  • Other similar activities that the applicant proposes, and EPA approves, that are consistent with Section 119 of the Clean Water Act.
Sustainability Sanitation & Clean Drinking Water Environmental Conservation +7 more

Middlesex County Grants for Nonprofits Highlights

Looking for Middlesex County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Middlesex County grants recommended for your specific programs in Connecticut.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Connecticut

Average Grant Size

What's the typical amount funded for Connecticut?

Grants are most commonly $102,799.

$102,799

Total Number of Grants

What's the total number of grants in Middlesex County Grants for Nonprofits year over year?

In 2024, funders in Connecticut awarded a total of 44,963 grants.

2022 40,971

2023 41,714

2024 44,963

Top Grant Focus Areas

Among all the Middlesex County Grants for Nonprofits given out in Connecticut, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Middlesex County Grants for Nonprofits changing over time?

Funding has increased by 26.46%.

2022 $3,687,355,257

2023 $3,626,469,446
-1.65%

2024 $4,586,184,577
26.46%

Connecticut Counties That Receive the Most Funding

How does grant funding vary by county?

Fairfield County, New Haven County, and Hartford County receive the most funding.

County Total Grant Funding in 2024
Fairfield County $2,060,422,894
New Haven County $962,256,077
Hartford County $506,655,014
New London County $103,900,627
Litchfield County $100,804,200