Best Addiction and Substance Abuse Grants in Minnesota

Nonprofit 501(c)(3) organizations in the Minnesota Twin Cities metro can seek up to US $5,000 to combat systemic racism or support arts programming. With a mission to foster charitable, educational, and community initiatives, Archie D & Bertha H Walker Foundation provides Minnesota groups addressing racial justice or arts engagement with annual grant opportunities.

Provide Substance Use Prevention Program Services to Serve American Indian Populations RFP

DHS is seeking to provide Substance Use Prevention Program Services to Serve American Indian Populations

DHS, through its Behavioral Health Administration (STATE), is seeking Proposals from qualified Responders to provide substance use prevention program services to serve American Indian (AI) populations.

The term of any resulting contract is anticipated to be for four and a half years, from January 1, 2027 until September 30, 2031.

Total Funds Available: $1,620,000

• Maximum Amount: $180,000 per year or $900,000 total per contract 
• In-kind or matching funds are optional
• Total Number of Grantees Anticipated: 9

With a mission to address addiction and substance use disorders, the Minnesota Department of Human Services Behavioral Health Administration provides Minnesota organizations with funding to combat opioid overdose in underserved, high-risk communities. Eligible responders can request up to US $350,000 to design or expand programs targeting populations disproportionately impacted by opioid-related overdose deaths.

Minnesota nonprofits, local governments, and Tribal Nations can seek funding for addiction and criminal justice programs in Minnesota, including chemical dependency and mental health treatment, supervision, and drug court support. The Minnesota Department of Public Safety’s Community Justice Reinvestment Grant Program supports services for justice-impacted individuals to reduce recidivism and further system involvement.

Minnesota public health agencies and partners working on overdose prevention and review can receive approximately US $20,000 to develop or enhance Overdose Fatality Review processes in Minnesota. Minnesota Department of Health provides Minnesota addiction and substance use organizations with resources to build collaborative OFR teams, engage public safety partners, and strengthen community responses to overdose deaths.

Behavioral Health Division

The Behavioral Health Division (BHD) oversees Minnesota's mental health and substance abuse prevention and treatment services that are paid for with state and federal funds. To support these services, BHD awards grants to counties, tribes, and nongovernmental providers. Behavioral health services include prevention, treatment, short-term and long-term care, as well as home and community-based services. BHD manages about 700 grants annually.

Request for Proposals for a Grantee to Provide Opioid Epidemic Response Services

Objective of RFP

The Opiate Epidemic Response Advisory Council (OERAC), in conjunction with the Minnesota Department of Human Services, through its Behavioral Health Administration (STATE), is seeking Proposals from qualified Responders to provide services aimed at addressing the opioid epidemic in Minnesota. These services include prevention and harm reduction for opioid use disorder (OUD), expansion and enhancement of the continuum of care for opioid related substance use disorders (SUD), and chronic pain management and alternative treatments.

The term of any resulting contract is anticipated to be for three and a half (3.5) years. STATE may extend the contract up to a total of five (5) years.

OERAC and STATE have identified four categories to meet the purpose of this RFP, each containing multiple focus areas. The four categories available for funding under this RFP are:

• Category A– Primary Prevention and Education for Opioid Related Substance Use Disorders
• Category B – Harm Reduction Services
• Category C – Expansion and Enhancement of Continuum of Care for Opioid Related Substance Use
• Category D – Chronic pain and Alternative Treatments

Nonprofit and local government organizations working on addiction and substance use disorders can apply for funding that supports prevention, treatment, housing, health, public safety, and related services, including in Minnesota. Focused on community well-being, the Confederated Tribes of Siletz Indians also funds education, arts, environment, cultural activities, and other charitable purposes nationwide.

Minnesota nonprofits, local governments, higher education institutions, and Tribes hosting AmeriCorps service programs can access funding to run evidence-based initiatives, including youth mental health and substance use recovery efforts. Minnesota addiction and substance use organizations may be eligible if they engage AmeriCorps members in research-based interventions and provide outcome data for evaluation and public reporting.

Minnesota 501(c)(3) nonprofits, public/government agencies, and Tribal Nations can seek funding for behavioral health programs addressing serious mental illness and substance use disorders. Focused on improving health outcomes and reducing disparities, Medica Foundation prioritizes community-led, trauma-sensitive, and collaborative initiatives, with grants up to US $200,000 over two years for program support.

Grants from the National Institutes of Health help Minnesota addiction and substance use organizations test SBIRT/P approaches for adult alcohol, tobacco, and other drug use and misuse. Eligible research teams must conduct prospective SBIRT/P implementation studies with adult populations experiencing health disparities, partnering with healthcare and community settings; projects may be based in Minnesota or elsewhere in the U.S. and territories.

Organizations providing addiction and substance use disorder treatment in Minnesota can seek funding to expand access to medication for opioid use disorder services. Grants from Minnesota Department of Human Services help Minnesota addiction and public safety programs address opioid and stimulant use, support MOUD, and strengthen a continuum of care including prevention, treatment, naloxone distribution, and recovery support.

Eligible organizations improving access to medication for opioid use disorder services in Minnesota can apply for the Minnesota Department of Human Services’ competitive grants, with awards up to US $5,757,000. Funding supports efforts to address opioid and stimulant use disorders, reducing related morbidity and mortality through expanded treatment access and behavioral health services.

Minnesota addiction and substance use organizations conducting research on adult health disparities can access funding through the National Institutes of Health to test SBIRT/P approaches for alcohol, tobacco, and other drug use and misuse. Projects must prospectively evaluate screening, brief intervention, and referral to treatment or prevention in collaboration with healthcare and community partners; multiple application cycles run through 2027.

Minnesota community organizations working on addiction and substance use disorders can receive US $65,000 - US $97,500 to promote tobacco cessation services and support adults who use commercial tobacco. Minnesota Department of Health’s Quit Partner Ambassadors Program funds outreach that increases awareness and use of Quit Partner programs across Minnesota communities.

Nonprofit and for-profit providers in Minnesota offering culturally specific or responsive substance use disorder services can seek up to US $4,000,000 to build capacity and sustainability. With a mission to support thriving communities, Minnesota Department of Human Services provides technical assistance for licensure, MHCP enrollment, rate enhancement, grant writing, and peer consulting or training.

Universities, research institutions, and similar organizations in Minnesota and other eligible U.S. locations can seek funding to provide research education in substance use and addiction. Focused on skills-development courses and hands-on research experiences, the NIH program supports efforts to engage trainees from diverse and underrepresented backgrounds in addiction and related biomedical and behavioral sciences.

The National Cooperative Drug/Device Discovery/Development Groups (NCDDG) program invites applications to foster innovative research in treating mental disorders and substance use issues. This initiative promotes collaboration between academia and industry, supporting diverse, multidisciplinary projects aimed at developing rational therapies and neurostimulation techniques. Applicants are encouraged to submit Letters of Intent 30 days before the proposal deadline to enhance project alignment with funding goals.

Clinician-scientist training programs in addiction and substance use disorders in Minnesota and other eligible U.S. locations can apply for institutional career development support, with awards up to US $750,000. Grants from US Dept. of Health & Human Services: National Institutes of Health support K12 programs providing intensive, supervised research training toward independent substance use and substance use disorder research careers.

The High Priority HIV and Substance Use Research funding opportunity aims to support innovative research that addresses the intersection of HIV and substance use. Researchers are encouraged to submit proposals that include a detailed research plan and preliminary data, exploring new avenues for prevention, treatment, and potential cures for HIV among people who use drugs. Applications are due by 5 PM local time, with optional Letters of Intent recommended 30 days prior.

The NCDDG program supports innovative research aiming to discover and develop new treatments for mental disorders, including substance use and alcohol use disorders. This initiative encourages collaborations between academic and industry partners to advance neurostimulation techniques and drug/device development. Applicants are invited to submit proposals that focus on specific projects utilizing the U01 mechanism, with a clear emphasis on rationally designed candidate agents and cutting-edge technologies. Letters of Intent are encouraged 30 days prior to the submission deadline.

The Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use initiative aims to enhance prevention services for infectious diseases among people who use drugs (PWUD). It encompasses two components: a biennial survey to assess service gaps and capacity, and increased support for testing and treatment services. The initiative seeks to improve data utilization in service provision, ultimately increasing testing for HBV, HCV, and HIV, and ensuring more PWUD engage in treatment and care.

About Samba RecoverySamba Recovery is dedicated to empowering individuals recovering from alcoholism and drug addiction by restoring confidence and fostering resilience. Through a foundation of compassion, support, and holistic care, we guide individuals toward renewed health and wellness, meaningful relationships, and the discovery of their inner strengths—assisting them to achieve their fullest potential.Hope for Addiction ScholarshipSamba Recovery’s Hope for Addiction Scholarship is an annual $1,000 award dedicated to encouraging more young people to join the fight against addiction by pursuing degrees that directly support individuals and families affected by substance use disorders.

We welcome applications from all eligible students, with special encouragement for those who are in recovery themselves or who have been impacted by addiction within their families.Application requirements:

• Proof of college enrollment or acceptance
• Pursuing a degree with the goal of working with individuals and/or families impacted by addiction
• Completed application form
• An original 500 to 1000 word essay on how you are planning to use your degree to help individuals and families struggling with addiction, and why helping those affected by substance use disorder is important to you

The Cooperative Agreement to Support Activities Related to Analgesics, Anesthetics, and Addiction (U01) aims to enhance research in Anesthesia, Addiction Medicine, and Pain Medicine. It focuses on critical areas such as clinical trial endpoints for chronic pain, outcome measures in stimulant use disorders, and neurodevelopmental assessments in pediatric patients. The initiative encourages applicants to propose comprehensive, evidence-based plans to improve the prescribing of analgesic and anesthetic drug products, with multiple awards available.

The Drug-Free Communities (DFC) Support Program aims to foster collaboration among community coalitions to combat youth substance use. Established by the Drug-Free Communities Act of 1997, it encourages partnerships among various stakeholders, including governmental and non-profit agencies. The program focuses on reducing substance use among youth and promoting protective factors within communities. This funding opportunity is available for those who have completed the initial funding cycle or experienced funding interruptions, supporting their ongoing efforts to create a healthier environment for youth.

The Drug-Free Communities (DFC) Support Program, initiated by the Drug-Free Communities Act of 1997, aims to bolster community coalitions dedicated to preventing youth substance use. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this program focuses on collaboration among various stakeholders, including government and non-profit entities, to effectively reduce substance abuse among youth and promote protective factors within communities.

The Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional) aims to support pilot and exploratory research in urgent substance use areas, including responses to emerging drug crises and evolving healthcare systems. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged. This funding opportunity emphasizes the need for rapid review to address pressing public health issues related to substance use and addiction in a timely manner.

Minnesota research institutions and other eligible organizations studying addiction and substance use disorders can access funding through the National Institutes of Health to investigate acute exposure to ultra-potent synthetic opioids and related combinations. This U.S. Dept. of Health & Human Services program offers up to US $1,500,000 for basic research on immediate and longer-term pathophysiological effects.