Best Large Grants for Nonprofit Organizations in Minnesota

The SLEEP Travel Grant for AASM Patient Advocacy Roundtable, funded by the American Academy of Sleep Medicine Foundation, aims to enhance sleep health by supporting organizations with limited financial resources. This grant offers $2,000 for travel and registration to the SLEEP 2026 meeting, fostering connections among members of the AASM Patient Advocacy Roundtable. This initiative emphasizes the importance of advocacy in sleep medicine and encourages participation in vital discussions surrounding sleep health.

The National Quantum and Nanotechnology Infrastructure (NQNI) program by the NSF aims to enhance research in emerging technologies like quantum computing and AI. By establishing a nationwide network of accessible research facilities, NQNI will facilitate innovation and collaboration among researchers. The program emphasizes user facility capabilities and plans for outreach, education, and workforce development, ultimately supporting the nation's quantum and nanotechnology advancements.

The Alpha Foundation Grant, established in 1997, focuses on enhancing the human condition by supporting educational, scientific, and charitable organizations. With a strong emphasis on biotechnology, the foundation aims to aid in disease discovery and cure. Eligible applicants must be tax-exempt 501(c)(3) organizations, primarily operating in Madison County, Alabama. The foundation does not fund individuals or political activities, ensuring its resources directly benefit public charities.

The NSF Mid-scale Research Infrastructure-1 Program supports projects that enhance research capabilities in science and engineering. This program provides funding for both design and implementation of mid-scale research infrastructure, emphasizing the development of a diverse workforce. By addressing specific community needs and promoting competitive research environments, the program encourages innovative approaches to infrastructure development. Proposals may involve upgrades, new acquisitions, or design efforts aimed at successful implementation of vital research tools.

Individual Provider Grants empower medical providers to contribute to communities through medical mission trips. These grants fund nonprofit organizations to assist with program costs. Applications are accepted year-round, but should ideally be submitted 30-60 days prior to the mission for timely processing. The Making a Difference Foundation reviews all applications monthly; however, meeting eligibility does not ensure funding at the requested amount.

American Chemical Society

The American Chemical Society (ACS) is a non-profit organization founded in 1876 and chartered by the U.S. Congress. ACS is committed to improving all lives through the transforming power of chemistry. Our mission is to advance scientific knowledge, empower a global community, and champion scientific integrity. Our vision is a world built on science.

What We Do

More than 145 years after our founding, we remain a champion for chemistry, its practitioners and our global community of members.

We’re recognized as a leading publisher of authoritative scientific information. Our 80+ peer-reviewed journals are ranked the “most-trusted, most-cited and most-read.”

We empower our members to advance chemistry, elevate their career potential, expand their networks, inspire future generations, collaborate globally and build communities that provide scientific solutions.

We provide broader networks that facilitate connections and open doors in a way no other professional organization can match!

ACS Graduate Student Success Grant

Purpose

To support graduate students (M.S. and Ph.D.), within one year of degree completion, whose education and training were disrupted due to termination or cancellation of research grants. Funding will be given to the Principal Investigator (PI) of the lab. This one-year award, the ACS Graduate Student Success Grant, will enable students to complete their degree programs. The grant seeks to lower the risk of a declining number of U.S.-trained chemists with advanced degrees, thereby preserving the strength and continuity of the scientific community.

Description

The ACS Graduate Student Success Grant provides $25,000 for one year to a faculty member who lost funding after October 1, 2024, that supports one or more graduate students. The award will also connect supported graduate students to ACS career development resources and programming to catalyze their transition into the workforce.

The grant funds will be awarded to exclusively support graduate students (M.S. and Ph.D.) who are within one year of degree completion and in need of funds to ensure degree completion. This grant supports currently enrolled graduate students who conduct research related to the chemical sciences in a department at a U.S.-based institution of higher education. Each institution of higher education can receive a maximum of one ACS Graduate Student Success Grant.

Applicant must provide a signed letter on institutional letterhead from the Vice President of Research (or equivalent), confirming the institution’s support, including the following:

• The PI’s loss of funding due to grant termination or cancellation after October 1, 2024.
• The names, current academic status, and anticipated graduation time of the impacted graduate students.

John A. & Louise V. Maslin Scholarship

Essay:

• On the topic “The Importance of Art, Science or Math in Society.”

Award:

• One time award of $1,000.

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Richard and Mary Krauland Scholarship

This scholarship was established to provide scholarship funding to pursue a career in math or engineering.

Scholarship Details

• Available to High School Seniors
• Nonrenewable

All ACCF Scholarships are merit based.

Our Mission

Empower donors to fulfill their passions and dreams by establishing charitable vehicles designed to create a positive and enduring impact on Jewish Buffalo, Western New York and the World.

Dr. Louis Sklarow Award

The Dr. Louis Sklarow Award was established in 1995 in honor of prominent Buffalo Physician and State University of New York at Buffalo Medical School Graduate Dr. Louis Sklarow.

The award is given to an outstanding graduate of Jewish faith from the Jacob’s School of Medicine who has shown by character and medical accomplishment great promise in becoming a fine physician and a person most likely to make a contribution to mankind and bring honor to the Jacob’s School of Medicine.

The Louis Sklarow Memorial Fund continues to fund research for the treatment and cure of Down Syndrome, Alzheimer’s disease and cancer through research performed at the University of Buffalo, Roswell Park Comprehensive Cancer Center and other renown institutions.

The Bergel Institute Fellowship - FS1: Cutting Edge or Pseudoscience? invites individuals to explore the intersection of science and human potential. This immersive program seeks to rigorously analyze over a century of scientific advancement, examining theories from quantum mechanics to consciousness. Through intensive research and mentorship, fellows will develop a comprehensive study that aims to redefine the applications of validated scientific theories, fostering public understanding and contributing to the evolution of human knowledge.

The Remote Biomarker Measurements in Microphysiological Systems Grant seeks innovative proposals to enhance remote biomarker analysis technologies for microphysiological systems, crucial for deep space missions. It prioritizes non-invasive, adaptable methods that allow for continuous monitoring of biomarkers without sample return. This initiative aims to advance personalized healthcare and biological research, addressing astronaut health in challenging environments. Eligible entities include U.S. institutions and collaborations with foreign entities under specific conditions.

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds. 

Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

George H. McDonnell Scholarship Fund

To support South Hadley residents who are studying civil or environmental engineering at a four-year college.

Additional Guidelines

• Students can receive up to $3,000 in scholarships from the Community Foundation.
• Scholarship awards could impact the financial aid offered by a college, and students are advised to check with their college financial aid offices about this.
• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. Some part and/or all the award could be considered taxable income. It is advisable students check with the college or tax accountant regarding this matter.

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

The Congressman Mark Foley Scholarship for Political Science Education Fund

Must be enrolled in a degree program with a major in Political Science.

The Diversity and Inclusiveness Grant Program by the American Philosophical Association aims to enhance the participation of underrepresented groups in philosophy. With funding up to $20,000, the program seeks innovative projects that impact diversity across various demographics including women, racial minorities, and LGBTQ+ individuals. Proposals are evaluated on their philosophical quality, feasibility, and potential broader impact, particularly within the US and Canada, making this an essential opportunity for promoting inclusivity in philosophical discourse.

Helen Frankenthaler Foundation Inc

The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.

Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.

Visual Arts & Education Grant

The Helen Frankenthaler Foundation supports public engagement with the visual arts through philanthropic, educational, curatorial, and research initiatives. It has expanded its grantmaking to sustain museums and visual arts institutions, supporting exhibitions, scholarship, and education across the field. The Foundation’s grantmaking priorities are currently organized across three areas:

• Climate Action and Sustainability
• Cultural Resilience
• Visual Arts & Education
  • Project-based support for exhibitions, publications, public programs, and academic initiatives that advance the presentation, study, and interpretation of the visual arts.
  • The Foundation supports discrete, institutionally grounded projects that advance the presentation, study, and understanding of the visual arts. Competitive proposals typically include:
    • Exhibitions, publications, and public programs focused on modern and contemporary art
    • Projects that expand access to collections, archives, and curatorial research
    • Academic and institutional initiatives in art history, studio practice, visual studies, museum and curatorial studies, conservation, and related areas of scholarship and teaching—particularly those involving university museums, galleries, and special collections
    • Conferences, programs, or initiatives led by professional organizations whose missions address the visual arts
    • Exhibitions and scholarly or public programs related to the 2028 centennial of Helen Frankenthaler
    • Projects must be clearly defined in scope, duration, and outcomes, and supported by appropriate institutional capacity. Requests for Visual Arts & Education funds should not be framed as general operating support. 

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Sue Aplington Kreutz Scholarship Fund

This scholarship fund was established in 2020 to support first-year college students accepted into a four-year college or university.

Grand Traverse Regional Community Foundation

The Grand Traverse Regional Community Foundation began in 1992 when a group of community champions came together around a vision to give back to our region then, now, and forever.

This vision lives on within our organization today as we support the people and places of Antrim, Benzie, Grand Traverse, Kalkaska, and Leelanau Counties and the Grand Traverse Band of Ottawa & Chippewa Indians.

Together with our partners, we spark positive change for a variety of local causes, including youth, arts and culture, education, environment, and health and human services, across our region.

Regional Scholarships

We believe that post-secondary education is key to healthy, resilient, and thriving communities and are pleased to partner with generous community donors to create and offer a variety of scholarship opportunities for local students across the region.

Robert Paul Dost Scholarship Endowment (Regional)

Available to graduating high school seniors in Antrim, Benzie, Grand Traverse, Kalkaska and Leelanau Counties who are planning to pursue electrical engineering. 

The Clinical and Translational Science Award (CTSA) Program aims to enhance the translation of scientific research into effective health interventions by establishing a national network of academic medical centers. This program supports integrated research and training environments for clinical and translational science, promoting the development of innovative methods and technologies. The reissuance of the CTSA Notice of Funding Opportunity invites eligible organizations to apply, with peer-reviewed applications prioritized for funding.

The NASA Earth System Science Research Program (ESSRP) has transitioned to six Earth science research spheres, including Atmosphere, which focuses on understanding atmospheric composition and structure. This program aims to enhance comprehension of phenomena affecting air quality and weather, addressing critical issues like stratospheric ozone recovery and tropospheric dynamics. Through annual ROSES funding opportunities, NASA supports research to improve modeling efforts and observations in atmospheric sciences, ultimately benefiting public health and environmental quality.

The FY 2027 Service Area Competition (SAC) aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive primary and preventive care. This initiative will support health centers in delivering high-quality services, addressing the needs of populations that face barriers to care. Each funding opportunity will specify service areas available for competition, ensuring effective resource allocation to improve community health outcomes.

The NASA ROSES25: A.15 Biosphere program aims to enhance our understanding of terrestrial and aquatic ecosystems through innovative research. This initiative focuses on biogeochemical interactions, biodiversity, and ecosystem function, utilizing satellite data and field studies. The program encourages reproducible and transparent science, fostering collaboration and interdisciplinary approaches. Proposals will undergo rigorous peer review, ensuring high standards and integrity in research outcomes that contribute to our knowledge of global environmental changes.

The Association of Legal Writing Directors (ALWD) History Grant is designed to support projects that research, interpret, or celebrate the history of ALWD and its contributions to the legal writing discipline. These grants reflect ALWD’s commitment to preserving the history of ALWD, honoring community contributions, and making ALWD’s history accessible to scholars, teachers, and practitioners into the future.

Types of Fundable Projects

• Oral History & Interview Projects - Projects may include interviews with founders, early leaders, past presidents, award winners, or other members central to ALWD’s history. 
• Archival Preservation & Digitization - A project may include scanning, organizing, and preserving historical materials such as conference programs, newsletters, board minutes, and committee records, accompanied by the creation of searchable digital archives for long-term access.
• Creative Dissemination Projects - Short documentary films, podcasts, interactive digital exhibits, timelines, or “museum-style” digital or physical installations are possible projects.
• Conference Integration  - Projects may include the preparation of history-focused materials for ALWD’s biennial conferences, such as poster sessions, anniversary exhibits, or a temporary “history wall.”
• Publications & Reflections  - Written projects may include essays, case studies, memoir pieces, or historical analyses suitable for publication 

The FY 2027 Service Area Competition (SAC) funding aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive preventive and primary health care. The initiative supports health centers in delivering essential services, ensuring that vulnerable populations receive the care they need. Service areas for competition are announced periodically, and additional areas may be added if existing centers are unable to continue their services.

The Schneider Electric SkillPointe Scholarship aims to close the skills gap in America by providing $3,000 scholarships to individuals pursuing careers in building automation and related fields. Funded by the SkillPointe Foundation, this initiative is designed for students enrolled in relevant training programs who are passionate about energy and sustainability. With a proven success rate of 95% in training completion and 97% employment, this scholarship empowers workers to thrive in high-demand industries without requiring a four-year degree.

The NSF Expeditions in Computing program aims to foster transformative research in computer and information science. By funding projects up to $15 million over seven years, it encourages multidisciplinary teams to tackle ambitious research agendas that redefine the future of computing. The program supports innovative areas such as new architectures for intelligence, advanced robotics, and next-generation communication, emphasizing the importance of collaboration across various fields to achieve groundbreaking advancements.

Gulf Coast Community Foundation

The Gulf Coast Community Foundation (GCCF) is dedicated to fostering charitable giving, empowering donors, and enhancing our community by facilitating investments in a diverse array of charitable causes. We serve a pivotal role in attracting, managing and distributing substantial charitable funds to enrich the lives of residents across George, Hancock, Harrison, Jackson, Pearl River, and Stone counties.

Established in 1989 as a 501(c)(3) organization, GCCF has invested more than $110 million into South Mississippi, providing administrative services to more than 120 funds that support local grassroots organizations in achieving their charitable objectives.

Jack A. Wilson Engineering Scholarship Fund

The Jack A. Wilson Engineering Scholarship Fund was established in December 2001 by Ms. Gertrude A. Wilson through the Gulf Coast Community Foundation to honor Mr. Wilson. The purpose of the fund is to award a scholarship for a college, junior college, or graduate school student entering their third or more years of engineering education. Applicants must be residents of Jackson, Harrison or Hancock County. Students meeting the criteria will be awarded a scholarship to be used toward the following, in order of priority: tuition and fees, room and board, books and supplies.

The Dream Big Technology Grant by KindCause.org aims to empower registered 501(c)(3) organizations by funding the implementation of Salesforce CRM. This initiative enhances nonprofit operations, enabling better donor management and campaign efficiency. With automated workflows and integrated tools, nonprofits can improve fundraising efforts and save valuable resources. Successful applicants will receive tailored technology roadmaps and potential funding for essential packages, ensuring they maximize their impact in the community.