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Best Grants for 501(c)(3) in Missouri

Find the perfect Grants for 501(c)(3) in Missouri on Instrumentl. 10,000+ Grants for 501(c)(3) in Missouri in the United States.

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Fred and Betty Worsh Scholarship Fund

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Fred and Betty Worsh Scholarship Fund, managed by the North Carolina Community Foundation, offers financial support to residents of New Hanover and Brunswick Counties who are U.S. citizens attending accredited four-year colleges or universities. Scholarships are available to undergraduates, graduates, and adult re-entry students, and may be renewed annually based on academic performance and financial need. Applications open on December 16, 2025, and close on March 3, 2026.
Education - High School Academic Scholarship Programs STEM / STEAM Education

AHS Headache & Migraine Competitive Grant Program - Adult Population RFP

American Headache Society (AHS)
Association/Society
Canada, United States
Up to US $250,000

American Headache Society

The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.

Headache & Migraine Competitive Grant Program

The Headache & Migraine Competitive Grant Program stands at the forefront of advancing headache medicine by funding groundbreaking quality improvement initiatives. This highly competitive grant program, offered through the collaboration between the American Headache Society and Pfizer, supports projects that have the potential to reshape the field by creating widely applicable tools and driving measurable improvements in patient care. 

Adult Population  RFP (Quality Improvement Solutions for the Diagnosis and Management of Migraine and Headache Disorder)

Seeking projects that drive meaningful impact in headache care through advancements in safety, clinical effectiveness, timely diagnosis, and equitable, patient-centered treatment. Submissions should feature bold, practical solutions in primary care and non-headache specialty settings, supporting adult populations with scalable, real-world innovations. 

Chronic / Acute Pain Neurological Diseases & Disorders

Postdoctoral Fellowships

American Diabetes Association Inc
Private
American Samoa, Guam +4 more
US $84,008 - US $252,024
The American Diabetes Association's Postdoctoral Fellowship Awards aim to foster emerging leaders in diabetes research. With a focus on innovative research, these fellowships provide up to three years of funding, including a stipend and allowances. Eligible applicants must hold a recent advanced degree and conduct research at U.S. affiliated institutions. This initiative not only supports career development but also contributes significantly to the mission of preventing and curing diabetes.
Diabetes

AGA-Gastric Cancer Foundation Ben Feinstein Memorial Research Scholar Award in Gastric Cancer

American Gastroenterological Association
Association/Society
North America
US $300,000
The AGA-Gastric Cancer Foundation Ben Feinstein Memorial Research Scholar Award provides $100,000 annually for three years to early-career faculty dedicated to gastric cancer research. Eligible candidates must have an MD, PhD, or equivalent and a full-time faculty position in North America. The award supports research in various areas related to gastric cancer, ensuring a minimum of 50% time commitment to the project, thus fostering independent careers in digestive diseases.
Gastrointestinal Cancers

Community Diversity Fellowship

American Psychiatric Association Foundation
Private
United States
Unspecified amount

Community Diversity FellowshipThe Community Diversity Fellowship is a unique opportunity for psychiatry residents from diverse backgrounds and residents who are committed to serving minority and vulnerable populations. The fellowship provides professional development, training, mentorship, and a field placement component (up to 15 hours per month) designed to add exponential impact in the delivery of culturally competent psychiatric care across hard to reach and traditionally underrepresented communities. These populations include—but are not limited to—American Indians/Native Alaskans, Asian Americans/Native Hawaiians/Native Pacific Islanders, Blacks/African Americans, Hispanics/Latinos, LGBTQ, and religious minorities.Program Benefits:

  • Attend one APA Annual Meeting
  • Attend one Fellowship Forum
  • Develop leadership skills in the field of psychiatry and advance understanding of the life experiences of racial ethnic minority communities
  • Gain hands on experience through field placement in a traditional underrepresented community mental health setting (up to 15 hours per month)
  • Gain an understanding of APA/APAF Governance through service on an APA Council, Committee, or APAF initiative 
  • Cultivate a professional network with psychiatrists interested in minority mental health and services through exclusive events through engagements with APA leaders.
    • Establish relationships and peer-mentorship with a diverse group of resident fellows with similar career interests and goals
Psychology Mental Health & Psychiatric Diseases

CLRA Research Grant Program

Childrens Leukemia Research Assn Inc
Private
United States
Up to US $30,000
The CLRA Research Grant Program, led by the Children’s Leukemia Research Association, focuses on funding innovative research aimed at uncovering the causes of leukemia and improving treatment options. Grants totaling $30,000 are awarded to U.S.-based researchers, with the intention of advancing scientific understanding and ultimately finding a cure. The program has made significant contributions to the high cure rates for childhood leukemia, showcasing the importance of continued research in this field.
Leukemia

NIMH Career Transition Award for Tenure-Track Intramural Investigators (K22 Independent Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.
Biology Health & Medicine Medical Education & Professional Training +1 more

Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional) (357550)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.
Cancer / Oncology Liver Disease Health Disparities & Social Determinants of Health

BRAIN Initiative: Brain-Behavior Quantification and Synchronization – Transformative Research on Behavior at the Organismal Level

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative's BBQS Program aims to revolutionize the study of brain function by facilitating high-resolution tracking of complex behaviors alongside neural activity. This transformative research opportunity seeks to develop innovative tools for minimally intrusive measurements of various biobehavioral functions while accounting for environmental variables. Emphasizing transdisciplinary collaboration, it focuses on creating new analytical frameworks that model neurobehavioral function as dynamic systems influenced by an organism's surroundings, thereby advancing our understanding of behavior at the organismal level.
Neuroscience Neurological Diseases & Disorders

Vanguard Resident Fellowship

American Psychiatric Association Foundation
Private
United States
Unspecified amount

Vanguard Resident FellowshipThe American Psychiatric Association has participated in the Minority Fellowship Program (MFP) since 1973. The program goals are to advance the quality of mental and substance use disorder prevention and treatment services and improve mental health care outcomes for all. The program seeks to increase the number and quality of psychiatrists who teach, administer services, conduct research, and provide direct mental and/or substance use disorder services to our Nation’s communities, and to treat and serve populations with higher prevalence of behavioral health challenges and conditions more effectively.Program Benefits: 

  • Funding to support your own innovative and creative Capstone Project
  • Monthly virtual professional development sessions
  • Gain access to employment opportunities through a virtual job fair
  • Gain an understanding of gaps in mental health care through the LEAD Institute curriculum
  • Receive mentorship from leaders in psychiatry through the Advocate & Protégé Program
  • Attend the Learning Lab, Fall Mental Health Summit, and Spring Leadership Summit, with the goal of enhancing your leadership skills in psychiatry by advancing your understanding of mental health inequities
  • Attend the APA Annual Meeting with the opportunity to present a poster or oral presentation of your Capstone Project
  • Gain understanding of APA Governance through service on an APA Council, committee or work group
  • Receive access to a lifetime network of psychiatrists
  • Establish long term relationships with resident fellows with similar career interests and goals
Addiction & Substance Use Disorders Wellness & Healthy Living Mental Health & Psychiatric Diseases

NCAA Jim McKay Graduate Scholarship

National Collegiate Athletic Association
Private
Canada, Puerto Rico +2 more
US $10,000
The NCAA Jim McKay Graduate Scholarship honors the legacy of journalist Jim McKay by awarding a one-time $10,000 scholarship to one male and one female student-athlete annually. Eligible candidates must have a minimum GPA of 3.5, demonstrate integrity, and show interest in sports communication. There is no limit to the number of nominations from institutions, highlighting the NCAA's commitment to supporting student-athletes in their academic and professional pursuits.
Sports & Athletics News Media & Communications Journalism

NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required) (357490)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33) invites research proposals for early phase clinical trials of natural products, including botanicals and dietary supplements, emphasizing scientific validity for further testing. Applicants may receive up to three years of funding for pharmacokinetics and bioavailability studies, with potential for an additional three years to evaluate clinical outcomes. This initiative aims to optimize natural product delivery through innovative study designs.
Food Safety Drug Safety

NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) (357492)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,050,000
The NCCIH Natural Product Early Phase Clinical Trial Award supports innovative clinical trials of natural products, such as botanicals and dietary supplements, with a strong scientific basis. Applications are encouraged to explore optimal delivery methods and combinations with other treatments. Funding is available for up to three years to assess the impact on target engagement and clinical outcomes, aiming to translate basic science findings into practical clinical applications.
Food Safety Drug Safety

NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) (357493)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $350,000
The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) grant invites applications for mid-phase clinical trials focusing on natural products such as botanicals and dietary supplements. It aims to advance scientific knowledge by determining optimal dosing and patient responses. Applicants must provide preliminary data demonstrating bioavailability and measurable impacts on target engagement. This initiative will not support efficacy trials for cancer treatments and encourages early contact with NCCIH scientific contacts.
Food Safety Drug Safety

NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22) aims to support postdoctoral fellows from underrepresented backgrounds in transitioning to tenure-track positions. This award provides essential funding for salary and research support for three years, enabling candidates to establish independent biomedical careers. Key deadlines for applications range from February 2025 to October 2027, ensuring ample opportunity for eligible researchers to secure funding for their career development.
Cancer / Oncology Medical Education & Professional Training Diversity, Equity & Inclusion

Promoting Population Health through Increased Capacity in Alcohol Epidemiology & the Prevention of Excessive Alcohol Use

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The CDC has announced funding for FY 2027 to enhance state capacity in alcohol epidemiology and prevent excessive alcohol use through the NOFO CDC-RFA-DP-27-0072. This initiative aims to equip states with essential tools and knowledge for effective public health measures against excessive alcohol use, a major preventable cause of death in the U.S. The program will also provide expert technical assistance and training on effective prevention strategies over a 5-year performance period.
Epidemiology & Public Health Addiction & Substance Use Disorders Preventative Healthcare

NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) (357462)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,000,000
The NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) aims to support innovative research in behavioral and social interventions for dental, oral, and craniofacial conditions. This funding opportunity includes a milestone-driven planning phase of up to 2 years, with potential transition to implementation for an additional 5 years, facilitating comprehensive trial development and assessment.
Dental Health Cognitive Intervention & Therapy Cognitive Science +1 more

Capacity Building for Global, Regional, and National Immunization Programs (363591)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Capacity Building for Global, Regional, and National Immunization Programs aims to enhance immunization efforts in key countries, focusing on the prevention and control of vaccine-preventable diseases like polio and measles. By strengthening immunization services and surveillance systems, the program will better address emerging health threats and reach under-immunized populations. Additionally, it will support sustainable practices through National Immunization Technical Advisory Groups and manage the National Stop Transmission of Polio program in Pakistan.
Preventative Healthcare Vaccines & Immunizations

Bridgestone Americas Trust Fund: Adaptive Sports in Schools Mobility Grants

Bridgestone Americas Trust Fund
United States
US $25,000

Adaptive Sports in Schools Mobility Grants

Request for Proposals

More than 7 million students in the U.S. receive special education services for disabilities in public schools. A 2010 study by the U.S. General Accountability Office found that students with disabilities participated in athletics at significantly lower rates than their peers. Currently, 2,490 k-12 public schools in the U.S. are members of the American Association of Adaptive Sports Programs schools and have adaptive sports programs for students.

The Bridgestone Americas Trust Fund seeks public schools pursuing funding to start adaptive sports programs or increase access to adaptive sports and equipment for children and youth. Bridgestone is offering eight $25,000 “mobility” grants to organizations that can establish new athletic programming for students with disabilities. Organizations must articulate a clear plan to provide access to new athletic programs for students with disabilities in one or more public schools for students grades K-12.

Education - K through 12 Sports & Athletics Youth Services +1 more

Pat R. Gereau R.N. Scholarship

Tulsa Community Foundation
Private
Tulsa County, Oklahoma, United States
Unspecified amount

Scholarship funds at TCF annually provide approximately $20 million in educational aid for students at institutions of higher learning. Each donor or group of donors determines the conditions for which the scholarships are awarded. The diversity of eligibility criteria reflects the variety of donor motivations to create or support scholarship funds.

Pat R. Gereau R.N. Scholarship

Available to students who are in an undergraduate program of study and pursuing a career in nursing at an accredited U.S. college, university, technical program or trade school in Tulsa, Oklahoma area.

Education - Higher Education Nursing Vocational & Trade Education

Greg Legg NEPA Diamond Scholarship

Scranton Area Foundation Inc
Private
United States
Unspecified amount

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating senior from a high school in Lackawanna, Luzerne, Wayne, or Pike county who plays baseball and plans to continue playing in college.

Education - Higher Education Sports & Athletics Baseball & Softball

The Alice M. Ditson Fund: Recording Projects

The Alice M. Ditson Fund
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Alice M. Ditson Fund supports recording projects that aim to document and promote the music of younger, lesser-known American composers. The fund prioritizes living composers of classical concert music, especially those in the early stages of their careers, while also recognizing established composers who deserve greater visibility. Eligible applicants include organizations with a fiscal sponsor or non-profit status, and projects must involve significant contemporary American music.
Classical Music

Elaine Sirkin Forbes Scholarship Fund

Pittsburgh Foundation
Private
United States
US $1,000

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Elaine Sirkin Forbes Scholarship Fund

The Elaine Sirkin Forbes Scholarship Fund was created at The Pittsburgh Foundation to provide scholarships for high school seniors graduating from Allegheny County Schools who wish to major in visual, performance or media art.

Award Type: Single-Year Award

Education - Higher Education Performing Arts Media Arts +1 more

Aim High Grant Program: One-Year Grants

New York Life Foundation
Corporate
United States
US $20,000
The Aim High Grant Program offers one-year grants of $20,000 to support out-of-school time programs for middle school youth. Funded by the New York Life Foundation, this initiative aims to enhance students' transition to high school by providing essential skills and guidance. Programs must demonstrate effective engagement strategies and serve low-income communities. This grant represents a vital investment in the future of young people, helping them develop academically, socially, and emotionally.
After School / Summer Educational Programs Education - Middle School

Friends of Reservoirs: Small Grant

Friends of Reservoirs
Private
United States
More than US $3,500
The Friends of Reservoirs: Small Grant program offers annual grants of $2,000 to member organizations of Friends of Reservoirs, with additional product donations bringing the total value over $3,500. This initiative, supported by generous sponsors, aims to enhance reservoir fisheries habitats. Applicants should note a $25 application fee, which contributes directly to the grant fund. This program focuses on fostering community engagement and improving aquatic ecosystems.
Fisheries

Pittsburgh ERG Scholarship Fund

Pittsburgh Foundation
Private
United States
Up to US $12,000

The Pittsburgh Foundation provides scholarship opportunities for students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four–year universities, graduate schools, and career/technical schools.

Pittsburgh ERG Scholarship Fund

The Pittsburgh ERG Scholarship formed by employees of Microsoft delivers on the mission of Microsoft’s local employee resource group to support diversity and inclusion. This scholarship enables high school students with disabilities and/or financial needs to go to college and pursue a career in technology. In addition, we hope to contribute to increasing the pool of people living with a disability enrolling in higher education and, in the long term, decrease the unemployment bias for this demographic. This scholarship will be awarded to promising high school seniors living in the city of Pittsburgh who plan to attend a vocational or academic college and have a financial need. The amount of this multi-year renewable scholarship is $12,000 payable over four years ($3,000 per year). (Immediate family members of Microsoft employees are not eligible for this scholarship.)

  • Average Award: $12,000 over 4 years.
  • Award Type: Multi-Year (up to 4 years). Recipients must maintain a cumulative GPA of 3.0 and enrollment in the stated major.
Education - Higher Education Physical Disabilities STEM / STEAM Education

Professional Nurses of Southwestern PA Scholarship Fund

Pittsburgh Foundation
Private
United States
Unspecified amount
The Professional Nurses of Southwestern PA Scholarship Fund, established by The Pittsburgh Foundation, supports nursing education for students in nine counties of southwestern Pennsylvania. This scholarship aims to assist those pursuing a Pre-Licensure RN, BSN, Master's, PhD, or DNP programs. Eligible applicants must have completed one semester in a nursing program and maintain a minimum GPA of 3.0. The fund continues the legacy of the Pennsylvania State Nurses Association, promoting leadership and service in nursing.
Education - Higher Education Academic Scholarship Programs Nursing

Grants for 501(c)(3) in Missouri Highlights

Looking for grants for 501(c)(3) in Missouri?


Read more about each grant below or start your 14-day free trial to see all grants for 501(c)(3) in Missouri recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grants for 501(c)(3) in Missouri

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Grants for 501(c)(3) in Missouri grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Grants for 501(c)(3) in Missouri over $25K in average grant size

29 Grants for 501(c)(3) in Missouri over $50K in average grant size

25 Grants for 501(c)(3) in Missouri supporting general operating expenses

100+ Grants for 501(c)(3) in Missouri supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for 501(c)(3) in Missouri?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Grants for 501(c)(3) in Missouri?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Grants for 501(c)(3) in Missouri year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Grants for 501(c)(3) in Missouri given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Grants for 501(c)(3) in Missouri changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081