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Large Grants for Nonprofit Organizations in Missouri

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Find the perfect Large Grants for Nonprofit Organizations in Missouri on Instrumentl. 100+ Large Grants for Nonprofit Organizations in Missouri in the United States

100+ grants

$7.5M total

$13.1K median

100+
Available grants

$7.5M
Total funding amount

$13.1K
Median grant amount

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Last updated: March 2, 2026. Next update: April 5, 2026.

Rolling deadline

Unspecified amount

BOK Charitable Contributions aims to enhance community life and economic wellbeing across several states, focusing on four key pillars: United Way, economic development, education, and basic needs. The foundation supports organizations that address poverty, education, and community health. Their strategic approach ensures impactful contributions, and they welcome grant applications year-round. BOK Financial's commitment is evident in its partnerships with local nonprofits, fostering sustainable growth and development in the regions they serve.

Rolling deadline

Unspecified amount

The Community Possible Grant Program by U.S. Bank aims to foster economic and workforce advancement, as well as safe and affordable housing. By partnering with 501(c)(3) nonprofit organizations, the program seeks to drive lasting change within communities through collaborative grantmaking. Priority is given to organizations that promote diversity, equity, and inclusion, and that address multiple pillars of work, home, and play. This initiative reflects U.S. Bank's commitment to creating a more equitable society.

Rolling deadline

Unspecified amount

The Costco Wholesale Charitable Contributions program prioritizes support for children, education, and health services within local communities. Nonprofit organizations seeking assistance must be 501(c)(3) certified and focus on monetary requests. Applications are reviewed within 4-6 weeks, factoring in community needs and collaboration. However, Costco limits grants to 10% of the program budget and typically restricts organizations to one request per fiscal year. They do not fund individuals or direct aid for various specific purposes.

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Rolling deadline

Up to US $300,000

The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.

Rolling deadline

Unspecified amount

State Farm's Good Neighbor Citizenship Company Grants aim to enhance community safety, development, and education. Focused on long-term impact, they support initiatives in auto and home safety, disaster preparedness, affordable housing, and educational programs. Eligible recipients include nonprofits, educational institutions, and government entities. However, funding is not available for individuals, religious programs, or organizations outside the U.S. By addressing critical community needs, these grants foster safer and more resilient neighborhoods.

Rolling deadline

More than US $100,000

The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.

Rolling deadline

More than US $100,000

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

Rolling deadline

Unspecified amount

The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.

Rolling deadline

More than US $50,000

The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.

Rolling deadline

Unspecified amount

The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.

Rolling deadline

Unspecified amount

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

Rolling deadline

Unspecified amount

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

Rolling deadline

Unspecified amount

The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.

Rolling deadline

Unspecified amount

The Stantec Community Engagement Grant is dedicated to enhancing the quality of life in communities where Stantec operates. Focused on arts, education, environment, and health and wellness, the grant supports initiatives that foster sustainable development and responsible practices. Organizations seeking funding must align with Stantec's values, emphasizing ethical practices and community impact. Preference is given to projects located near Stantec offices, ensuring a more significant local impact through their contributions.

Rolling deadline

Unspecified amount

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

Rolling deadline

Unspecified amount

The Tony Robbins Foundation Grant aims to empower individuals and organizations to improve the lives of marginalized communities, including youth, seniors, and the homeless. By providing financial support to aligned nonprofits, the foundation seeks to create impactful changes globally. Eligible organizations must be 501(c)(3) nonprofits or recognized international entities, with a mission statement that resonates with the foundation's goals. The foundation does not fund personal projects or startups.

Rolling deadline

Unspecified amount

Wells Fargo Community Giving supports nonprofit organizations focusing on financial health, housing affordability, small business growth, and sustainability. The grant cycle runs from February to October, inviting organizations with 501(c)(3) status or equivalent to apply. Funding is prioritized for programs addressing critical community needs, while limited support is available for local initiatives like disaster relief and arts. Organizations must demonstrate fiscal stability and potential impact to be considered for funding.

Applications due Apr 15, 2026

Unspecified amount

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

Applications due May 1, 2026

US $30,000 - US $350,000

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

Applications due May 15, 2026

Unspecified amount

The Robinson Foundation Grant, established in 2016, aims to alleviate hardships faced by individuals and communities, demonstrating God's love through charitable contributions. As a family-operated foundation, it focuses on creating meaningful, long-term impacts in various areas including animal welfare, education, and disaster relief. Organizations eligible for funding must be 501(c)(3) public charities. The foundation prioritizes fiscally responsible projects with the potential for tangible results, while not supporting capital projects.

Applications due May 29, 2026

Unspecified amount

The Kroger Foundation is dedicated to uplifting communities through significant charitable contributions, having donated over $1.9 billion in the past six years. Their focus on combating hunger through the Zero Hunger | Zero Waste initiative exemplifies their commitment to social impact. Annually, they provide over $300 million to nonprofit organizations aligned with their mission, promoting health, education, and disaster relief while fostering diversity and inclusion. This initiative reflects Kroger's belief that strong communities are a shared responsibility.

Applications due Jul 1, 2026

Unspecified amount

The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.

Applications due Sep 25, 2026

More than US $50,000

The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.

Applications due Oct 16, 2026

Unspecified amount

Insperity's Corporate Contributions program emphasizes community involvement and corporate citizenship, providing philanthropic grants and event sponsorships to 501(c)(3) nonprofit organizations. Eligible organizations must engage Insperity employees or contribute to the communities where they operate. The program aims to support nonprofits in achieving their service goals and enhancing community welfare. Applications must be submitted 90 days prior to events, and funding requests can be made once a year.

Applications due Oct 31, 2026

Unspecified amount

The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.

Letter of inquiry due Oct 31, 2026

Unspecified amount

The TJX Foundation Grants support nonprofit organizations located within 15 miles of a TJX store that align with their community mission. Eligible areas include basic needs, education for at-risk youth, workforce training, and safety from domestic violence. Organizations must be a registered 501(c)(3) for at least 12 months and have a nondiscrimination policy. Applications are invited through a Letter of Inquiry, with funding decisions based on community impact.

Applications due Nov 15, 2026

Unspecified amount

The United Way KGC Impact 100 Grant seeks proposals from local nonprofit organizations that address critical health and human service needs in the Kansas City region. Selected organizations will receive a one-year unrestricted grant, enhancing their visibility and connections within the United Way network. This initiative emphasizes diverse approaches in Health, Education, and Financial Stability, ensuring a comprehensive impact across various community sectors. Organizations are encouraged to apply based on alignment with United Way's funding goals and community needs.

Showing 27 of 100+ results.

Large Grants for Nonprofit Organizations in Missouri Highlights

Last updated: March 2, 2026. Next update: April 5, 2026.

Top Searched Large Grants for Nonprofit Organizations in Missouri

Large Grants for Nonprofit Organizations in Missouri from Private Funders

Large Grants for Nonprofit Organizations in Missouri over $20k

Large Grants for Nonprofit Organizations in Missouri for Projects & Programs

Large Grants for Nonprofit Organizations in Missouri from Government Funders

Grant Insights : Large Grants for Nonprofit Organizations in Missouri

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Missouri grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

36 Large Grants for Nonprofit Organizations in Missouri over $25K in average grant size

28 Large Grants for Nonprofit Organizations in Missouri over $50K in average grant size

30 Large Grants for Nonprofit Organizations in Missouri supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Missouri supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Missouri?

Most grants are due in the first quarter.

31.1%

27.4%

20.1%

21.5%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Missouri?

Grants are most commonly $13,125.

$375 $375 Min.

$13,125 $13.1 K Median

$96,717 $96.7 K Average

$1,250,000 $1.3 M Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $100,181.

$100,181

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Missouri year over year?

In 2024, funders in Missouri awarded a total of 20,179 grants.

2022 39,922

2023 39,688

2024 20,179

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Missouri given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Missouri changing over time?

Funding has increased by -61.86%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $2,016,605,547
-61.86%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County	Total Grant Funding in 2024
St Louis County	$1,060,800,664
Jackson County	$493,752,997
St Louis City	$372,479,568
Greene County	$134,480,889
Cole County	$77,030,794

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100+ Available grants

$7.5M Total funding amount

$13.1K Median grant amount

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Get matched with grants that actually fit.

Get new Large for Nonprofit Organizations in Missouri grants weekly

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La Roche, Inc.

Stantec

Insperity

Large Grants for Nonprofit Organizations in Missouri Highlights

Top Searched Large Grants for Nonprofit Organizations in Missouri

Grant Insights : Large Grants for Nonprofit Organizations in Missouri

Grant Availability

100+ Large Grants for Nonprofit Organizations in Missouri grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

36 Large Grants for Nonprofit Organizations in Missouri over $25K in average grant size

28 Large Grants for Nonprofit Organizations in Missouri over $50K in average grant size

30 Large Grants for Nonprofit Organizations in Missouri supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Missouri supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Typical Funding Amounts

Average Grant Size

Total Number of Grants

2022 39,922

2023 39,688

2024 20,179

Top Grant Focus Areas

Funding Over Time

2022 $4,698,402,122

2023 $5,287,874,816 12.55%

2024 $2,016,605,547 -61.86%

Missouri Counties That Receive the Most Funding

Browse Nonprofit Grant Resources

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Search Through Large Grants for Nonprofit Organizations in Missouri

100+
Available grants

$7.5M
Total funding amount

$13.1K
Median grant amount

2023 $5,287,874,816
12.55%

2024 $2,016,605,547
-61.86%