Best Large Grants for Nonprofit Organizations in Missouri

The AI for Economic Opportunity Fund, established by the GitLab Foundation, aims to catalyze transformative economic opportunities using advanced AI technologies. This funding round invites bold proposals that leverage AI to enhance economic mobility, improve service delivery, and create new educational pathways. Grantees will receive $250,000 in funding, technical support, and access to a network of practitioners. The fund seeks projects that demonstrate ethical awareness and promote fairness in AI deployment.

The Blueprint Neurotherapeutics Network (BPN) supports the development of biologic-based therapies for nervous system disorders. This initiative encourages innovative research in biologics, including proteins, antibodies, gene therapies, and cell therapies. The program facilitates collaboration with NIH-funded experts and contract research organizations, ensuring institutions retain IP rights for developed candidates. Key deadlines for grant applications span from January 2025 to July 2027, emphasizing the importance of timely submissions for interested applicants.

The All Kids Play: Youth Sports Grant aims to support families and community-based organizations in low-income areas, ensuring access to recreational sports for children in grades K-12. This grant assists those who struggle to afford youth sports, providing essential funding on a first-come, first-served basis. Eligible organizations must demonstrate budget constraints and operate in areas with high low-income student percentages, promoting inclusivity in youth sports participation.

This grant opportunity from the NIH aims to enhance mechanistic research on precision probiotic therapies through a biphasic R61/R33 award mechanism. It encourages innovative studies to identify specific biological factors influencing probiotic responses, thereby improving clinical outcomes. The program supports up to five years of research, with the initial phase focused on discovering unique host characteristics and the second phase assessing improvements in probiotic efficacy through rigorous studies.

The Extramural Discovery Science Accelerator Award supports the commercialization of ongoing cancer research projects, focusing on experiments that facilitate technology validation and de-risking. Applications are accepted on a rolling basis, with a budget of up to $75,000 for one year. This award encourages independent investigators at any career stage to advance their technologies, with a strong emphasis on commercial viability and collaboration within a learning community.

The USA Swimming Foundation's Youth Learn-to-Swim Grant aims to increase access to swim lessons for children across the nation. By providing funding to swim lesson programs, the foundation ensures that financial barriers do not prevent children from learning this vital life skill. Grants can be used for free or reduced-cost lessons, addressing the needs of underserved communities and promoting safety through swimming education.

The Puffin Foundation's Annual Artist Grant Program, focused on odd years, supports individual artists and non-profit organizations in the genres of video/film and theater. Grants, typically around $1,750, aim to uplift marginalized voices in the arts. Applicants must be U.S. citizens or permanent residents with an SSN. The program excludes proposals in other disciplines and projects involving AI. This initiative prioritizes diverse artistic expression and aims to maximize funding impact for those with limited financial resources.

The NARMS Cooperative Agreement Program aims to enhance antibiotic resistance surveillance in retail food specimens, building on the National Antimicrobial Resistance Monitoring System initiated by the FDA in 1996. This program seeks to improve detection of antibiotic-resistant bacteria in food commodities and expand sampling sites. By strengthening monitoring efforts, it aims to protect public health and achieve measurable outcomes aligned with NARMS objectives, contributing to national efforts against antibiotic resistance.

The Lisa and Douglas Goldman Fund, a private foundation established in 1992, is dedicated to enhancing the Jewish community by awarding grants that foster inclusivity and vibrancy. The fund invites proposals from organizations committed to combating antisemitism and supporting progressive initiatives such as climate action and reproductive rights. Eligible applicants must hold 501(c)(3) status and can submit one request per year, focusing on projects in the San Francisco Bay Area or nationally.

The Advancing Research Careers (ARC) Predoctoral to Postdoctoral Transition Award (F99/K00) supports late-stage graduate students from diverse backgrounds in transitioning to postdoctoral positions. This phased award aims to facilitate doctoral dissertation completion and subsequent career development in biomedical research. Participants will engage in mentoring, networking, and professional development activities, preparing them for impactful careers that often require postdoctoral training. Key deadlines for applications span from February 2025 to January 2028.

The Pediatric Physical Therapy Research Grant, funded by the Foundation for Physical Therapy Research, supports innovative research to enhance physical therapy practices. By fostering early career researchers, the grant aims to build a strong evidence base in physical therapy. Over the past 46 years, this initiative has created a sustainable pipeline for research funding, benefiting patients and healthcare professionals alike, while advancing the profession's evidence-based practices.

The Betsy & Ryan Colwell Mentorship Scholarships for Women in Thoracic Surgery support early-career female cardiothoracic surgeons by facilitating mentor relationships and networking opportunities at the WTS Annual Conference. Each scholarship, valued at $2,500, covers conference registration, lodging, and travel expenses. Two scholarships will be awarded annually starting in 2025, aiming to empower women in a specialty where they are underrepresented and help them navigate their challenging career path.

The Future of Work program by the Russell Sage Foundation investigates the decline in quality of low-wage jobs in the U.S. It explores factors such as outsourcing, immigration, union decline, and technological changes. Current research focuses on minimum wage impacts, offshoring effects, and job search behaviors influencing employment outcomes, particularly for women and minorities in the post-recession labor market. This grant aims to enhance understanding of these critical issues affecting low-education workers.

The Moffat Geriatric Research Grant, offered by the Foundation for Physical Therapy Research, supports innovative physical therapy research. With a commitment to enhancing healthcare outcomes, this grant aims to fund both emerging and established researchers. By addressing health disparities and fostering a new generation of researchers, the program seeks to advance evidence-based practices that improve movement and health across diverse populations.

The Hearst Journalism Awards Program, established in 1960, supports journalism education by awarding scholarships to outstanding undergraduate students. With $700,000 available, this program includes competitions across writing, photojournalism, audio, television, and multimedia categories. Each participating university can submit two entries per competition, fostering excellence in journalism. The Hearst Foundation, a long-standing supporter of educational initiatives, underlines the importance of quality journalism and supports students actively engaged in media.

The Hearst Journalism Awards Program, established in 1960, supports journalism education at the collegiate level by offering scholarships for outstanding performance. The 2024-2025 program includes 14 competitions across various media forms, with awards totaling up to $700,000. Participation is open to undergraduate journalism majors and minors at ACEJMC-accredited institutions. The program aims to encourage excellence in journalism and provides financial support to both students and their schools.

The Hearst Journalism Awards Program, established in 1960, supports undergraduate journalism education with up to $700,000 in awards through various competitions. Open to ACEJMC-accredited students, it includes writing, photojournalism, audio, television, and multimedia contests. Each participating university can submit two entries per competition, promoting excellence in journalism while providing schools with stipends. While primarily for journalism majors, exceptions exist for photojournalism entrants, fostering inclusivity and creativity in the field.

The Hearst Journalism Awards Program offers significant support for aspiring journalists, providing scholarships and recognition for excellence in various media formats. Established in 1960 by the William Randolph Hearst Foundation, the program includes multiple competitions in writing, photojournalism, audio, television, and multimedia. With up to $700,000 in awards, it encourages undergraduate students at accredited institutions to showcase their talents, fostering the next generation of journalistic talent.

The Small Rural Hospital Improvement Program (SHIP) Grant, offered by the Minnesota Department of Health, aims to enhance healthcare quality in eligible small rural hospitals across the U.S. and its territories. With a total funding pool of $1,755,000, MDH plans to award 18 grants ranging from $45,000 to $125,000. This program, which requires no matching funds, supports hospitals in meeting Medicare data system requirements and improving overall healthcare services.

Lindsay Lloyd North Korea Freedom Scholarship

The Lindsay Lloyd North Korea Freedom Scholarship (supported by the George W. Bush Foundation) provides one or more annual scholarships for up to $10,000 to lawful permanent residents of the United States, U.S. citizens or refugees who were born in North Korea pursuing an educational program in the United States or its possessions. North Korean-born individuals pursuing a degree in accredited colleges and universities in the United States with South Korean citizenship are eligible to apply.

This scholarship may be renewed on an annual basis by completing the scholarship application in full. Renewal applications will be reviewed alongside first-time applicants.

The Kress Conservation Fellowships, offered by the Samuel H. Kress Foundation, support post-graduate training for emerging conservators in various specialty areas like paintings and textiles. The fellowships provide competitive grants to museums for supervised internships, running 9 to 12 months. Eligible applicants must have completed a master's degree in conservation. Preference is given to institutions without recent Kress Fellows, ensuring diverse opportunities across North America and beyond.

The JUF Springboard Access Grant aims to make Jewish programming more accessible for teens in grades 8-12 in the Chicago area. This grant covers up to 50% of the tuition costs for first-time participants in multi-day programs organized by approved Jewish nonprofits. It encourages teens to engage with their community and explore new interests while ensuring financial barriers are lowered. Eligible teens are expected to share their experiences with the organization after participating.

The Alexander H. & Helen V. Smith Research Award, presented by the Mycological Society of America, supports research on macrofungi specimens collected by Alexander H. Smith. This award facilitates access to crucial collections at the University of Michigan Herbarium, aiding mycologists and students in advancing their studies. Recipients are encouraged to attend the MSA annual meeting to engage with the mycological community, enhancing collaboration and networking opportunities.

The Health-Surgical Care Fund Grant, provided by the Orange County Community Foundation, aims to support underfunded, volunteer-driven organizations offering surgical care for various physical or cosmetic deformities. The Fund prioritizes programs with a significant long-term impact, ensuring services are free to the community. Eligible organizations must demonstrate accountability, transparency, and a commitment to serving U.S. citizens, while allocating at least 70% of their budget to direct program expenses.

The Grant and Bridget Daugherty Nursing Scholarship, administered by the Coral Gables Community Foundation, offers financial assistance to Coral Gables High School seniors pursuing a Nursing major. The scholarship ranges from $1,000 to $5,000 for one academic year. Recipients must maintain a minimum GPA of 3.0 and submit transcripts annually to retain funding. This initiative supports students committed to academic excellence and a career in healthcare.

The Community Foundation of Central Wisconsin offers a robust college scholarship program, providing over $325,000 annually to students in Portage and Waushara counties. Scholarships, ranging from $500 to $40,000, are available for high school seniors, college students, and non-traditional learners. Selection criteria include financial need, community involvement, academic achievement, and extracurricular activities, ensuring support for a diverse range of educational pursuits.

The Dave Ragan Jr. Memorial Golf Scholarship, managed by the Coral Gables Community Foundation, offers financial support to graduating seniors with a passion for golf. Applicants must have a minimum GPA of 3.0, demonstrate financial need, and intend to play golf at the collegiate level. This scholarship honors the legacy of Dave Ragan Jr. and aims to foster educational opportunities through sports. Over the years, the Foundation has awarded over $2.9 million in scholarships, emphasizing academic achievement and community engagement.