Best Large Grants for Nonprofit Organizations in Missouri

The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.

The Bonnie Plants 3rd Grade Cabbage Grant Program inspires young students to cultivate a love for gardening by providing free oversized cabbage plants to 3rd grade classrooms across the continental U.S. Initiated in 1996, the program encourages hands-on learning about where food comes from. Each year, students compete for a $1,000 prize awarded to the best cabbage grown, fostering excitement and education about agriculture. This initiative not only promotes environmental awareness but also engages students in practical science.

The Creation & Development Fund, administered by the National Performance Network, supports the creation and mobility of artistic works that promote racial and cultural justice. It fosters collaboration between artists and communities through financial support, enabling artists to develop meaningful relationships and present their work. The fund emphasizes equity, access, and the importance of public engagement, ensuring that diverse voices are represented while addressing systemic injustices in the arts.

The John K. Fairbank Prize in East Asian History, awarded by the American Historical Association, recognizes exceptional scholarly work in the history of East Asia, particularly focusing on books published after 1800. Eligible works must demonstrate high literary merit and can be nominated by authors or publishers. The prize aims to highlight significant contributions to the historical disciplines, with recipients announced in October 2025 and honored at the January 2026 AHA annual meeting in Chicago.

The ACS-Hach High School Chemistry Classroom Grant aims to enhance chemistry education by providing funding for innovative teaching ideas. Since its inception in 2008, over 700 teachers have benefited from grants of up to $1,800. Eligible applicants are U.S. high school chemistry educators, and the funding can be used for laboratory supplies, instructional materials, professional development, and student-led field studies, fostering a deeper understanding of chemistry.

The Garden Club of Houston, established in 1924, promotes gardening and environmental conservation through various community initiatives. Their funding supports nonprofit organizations and government entities, focusing on projects that enhance public landscapes, educational resources, and community gardens. Grants are not awarded for operating funds or endowments, with preference given to projects within the greater Houston area. This commitment to civic improvement underscores their mission to foster a love of gardening and environmental stewardship.

The Asian Cultural Council (ACC) offers Organization Grants to arts and culture organizations in Asia and the U.S., promoting cultural exchange through travel and collaborative activities. These grants support immersive experiences, research, and access to artistic communities, fostering international dialogue and relationship-building. Organizations must be nonprofit or educational institutions, legally registered in eligible regions, and demonstrate a minimum of five years of relevant programming. ACC provides additional support to enhance project feasibility.

The Pop Culture Collaborative offers Major Grants to support initiatives that promote long-term narrative change and social justice through pop culture. Targeting U.S.-based nonprofits, for-profits, and individuals, these grants aim to engage mass audiences in transformative experiences. With a focus on communities often marginalized, the Collaborative's efforts are designed to foster a pluralistic society where everyone belongs. Grants range from $20,000 to $200,000, depending on project scope and duration, with applications reviewed biannually.

The American Australian Association's Graduate Education Fund offers scholarships for American and Australian students pursuing Masters, Ph.D., or Postdoctoral research in various fields, including Science, Technology, and Sustainability. Established in 2002, the fund has awarded nearly $11 million to over 350 scholars. Scholarships up to $40,000 support travel, living, and tuition costs. Applications are accepted biannually, with specific periods for each direction of study. It also includes scholarships for Indigenous students.

The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.

The Amy Clampitt Poet Residency Program, established by The Berkshire Taconic Community Foundation, offers a six-month residency for poets at Amy Clampitt's former home in Lenox, Massachusetts. This program aims to foster the study and promotion of poetry, providing a peaceful retreat for a poet to focus on their craft. Selected poets receive a monthly stipend of $4,000 and are encouraged to make their creative work a priority during their stay.

The Robanna Fund, established in 1992 by Robert and Deanna Levy, supports students pursuing careers in healthcare. Administered by the Hawai‘i Community Foundation, the fund awards scholarships averaging $6,000, depending on various factors such as the number of qualified applicants and donor preferences. Eligible applicants must maintain a minimum GPA of 2.0, reside in Hawai‘i, intend to major in a health-related field, and demonstrate financial need. This initiative aims to cultivate future healthcare professionals in the community.

The Civic Experiment Grant by the Trust for Civic Life supports innovative, community-driven projects aimed at enhancing civic engagement. It focuses on rural areas, empowering local leaders to tackle challenges collaboratively. Grants up to $25,000 are available for organizations that are non-partisan and primarily serve rural communities, emphasizing inclusivity and sustainable impact. The next nomination period begins in early 2026, following a closed cycle for 2025. This initiative fosters long-term civic infrastructure and community resilience.

The GHI Doctoral and Postdoctoral Research Fellowships offer support for European and North American scholars pursuing research in German and European history, German-American relations, and North American history. Awarded by the German Historical Institute, these fellowships prioritize projects requiring primary sources in North America and are available for one to four months. Monthly stipends are € 2,000 for doctoral students and € 3,400 for postdoctoral scholars, with additional airfare reimbursement for European recipients.

Alpha Omega Alpha Honor Medical Society

Alpha Omega Alpha, founded in 1902, is the national medical honor society. Its mission is:

• Alpha Omega Alpha — dedicated to the belief that in the profession of medicine we will improve care for all by:
• recognizing high educational achievement;
• honoring gifted teaching;
• encouraging the development of leaders in academia and the community;
• supporting the ideals of humanism; and
• promoting service to others.

Helen H. Glaser Student Essay Award

To encourage medical students to write scholarly essays relevant to medicine. Winning essays will be published in an issue of The Pharos.

Only one entry may be submitted per student.

Requirements

• Essays must be written while the student is in medical school, must be the work of a single author, and must be an original work. The essay must not be offered to, or published by, any other journal or entered in any other contest prior to submission or during, the AΩA selection process.
• The essay must be related to medicine.
• Essays should not be fictional or written in first person, but academic/scientific in theme.
• The essay must not exceed 15 double-spaced pages of 12-point type with minimum 1-inch margins, exclusive of reference listing. The author’s name and essay title must be on each page, and all pages must be numbered.
• Unique references, numbered consecutively, should be limited to 20. (Reference citation of a website is not acceptable unless a site is the sole source of the information or has official academic credentials. Examples of acceptable sites are official government web pages such as that of the National Institutes of Health.)
• The Pharos Editorial Board suggests that authors review George Orwell’s “6 Rules for Writing”.
• Essays that are not selected as award recipients may be submitted to other contests/publications after the winners are announced.
• Essays not meeting all requirements will not be considered.

The Community Heart & Soul Seed Grant Program offers $10,000 in startup funding for community-driven groups in small towns to adopt the Community Heart & Soul model. Applications are accepted until 11:59 p.m. EST on the last business day of each month, with funding decisions made the following month. This initiative aims to empower residents to engage in local development and foster community connections.

The Paul Purcell "Kids Win!" Annual Baird Education Grant honors the legacy of former Baird CEO Paul E. Purcell, who dedicated his life to educational causes. Established in 2020, this grant supports 501(c)(3) organizations that ensure all children, regardless of circumstances, have access to quality education. Funded by Baird and its associates, it prioritizes programs serving diverse and underserved populations, embodying Purcell's belief that every child deserves the opportunity to succeed.

Confederated Tribes of Siletz Indians

The Confederated Tribes of Siletz Indians is a sovereign nation and has three main branches of government – Judicial, Executive, and Legislative. One of our most important resources is our people.

Education

The Confederated Tribes of Siletz seeks to provide opportunities for Tribal members to reach potential, establish independence and improve quality of life through lifelong learning and education.

Arthur S. Bensell Memorial Scholarship

Arthur S. Bensell was an educator, civic leader, Tribal Council member and Tribal Chairman. He spent many years in service to his community and Tribe as Mayor of the City of Siletz and tribal leader.

Art attended Ohio State University and graduated from Heidelberg College in 1934. During his career with the Bureau of Indian Affairs, he served as a teacher, principal and reservation principal in Minnesota, Alaska and North Dakota. Upon returning to Siletz, Art became involved in tribal business affairs and served many years on the Tribe’s Education Committee and always strived for better educational opportunities for Tribal members.

A memorial scholarship fund was established through the Confederated Tribes of Siletz Indians to honor and award Tribal members in education. The $1000 scholarship is administered by the Tribal Education Committee and strengthened by various fund raising activities throughout the year.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Jeanette Elmer Scholarship

This opportunity is provided to honor the life and legacy of Jeanette Elmer.

The purpose of the Jeanette Elmer Scholarship program is to provide financial assistance to eligible American Indian and Alaska Native graduate students pursuing degrees full-time at an accredited institution in library science.

This opportunity is a need-based award.

This grant aims to enhance safety and health in U.S. mining operations through research in automation, robotics, and intelligent systems. It addresses critical issues like emergency communication and self-escape reliability while supporting the development of field-ready solutions. By leveraging advanced technologies, the initiative seeks to improve miner safety and health, reduce hazardous exposures, and foster community engagement. Applicants must be U.S. academic institutions with accredited mining programs, linking project goals to documented health burdens.

The AOAP Life Jacket Grant supports aquatic facilities in drowning prevention by offering funds for swim lessons and life jackets. Administered by the Association of Aquatic Professionals, the program aims to provide at least 100 free lessons and distribute 500 life jackets annually. This initiative promotes safety education and awareness of life jacket usage, ensuring that underserved communities have access to vital water safety resources. Applications are open to AOAP members meeting eligibility criteria.

The HFM Foodservice Scholarship Fund supports students in Hawaii pursuing education in Culinary Arts or Agriculture. Applicants must demonstrate financial need, maintain a minimum GPA of 2.7, and attend an accredited institution in the U.S. Preference is given to prior recipients in good academic standing. This scholarship aims to empower future leaders in the foodservice industry by providing financial assistance to deserving candidates.

The Bee a Rae of Sunshine Foundation – MaKenzi Rae Cash Memorial Animal Compassion Scholarship, offered by the Community Foundation of Carroll County, aims to support students dedicated to animal welfare. Eligible applicants must be graduating high school seniors from Carroll County, Maryland, with a minimum GPA of 3.0 and at least 125 service hours. This scholarship reflects MaKenzi Rae Cash's love for animals and her commitment to kindness and anti-bullying advocacy.

The Air Force Fiscal Year 2027 Young Investigator Program (YIP) is designed to support early career scientists and engineers who have recently obtained their Ph.D. This initiative aims to promote innovative basic research in science and engineering while enhancing the professional growth of promising investigators. Awards are available to U.S. institutions where the principal investigator is a full-time employee. Eligible candidates must be U.S. citizens, nationals, or permanent residents.

The J.M. Heberlig/B.J. Helterbran Scholarship Fund, established by dedicated educators, supports Pennsylvania residents pursuing degrees in Art Education or Recreation & Parks. This scholarship aims to alleviate the financial burden on students entering their second, third, or fourth year at a 4-year institution. With a focus on academic achievement, a minimum GPA of 2.8 overall and 3.0 in the major is required, alongside a demonstrated commitment to education and community service.

The Jason Reynolds / Simon & Schuster Travel Grant supports five black/African American youth and teen services librarians annually. Each grant, ranging from $1500 to $3000, covers expenses for travel, housing, registration, and attendance at the ALA Annual Conference, including the Coretta Scott King Awards Breakfast. This initiative aims to empower underrepresented librarians in their professional development and community engagement.

The Olney Medal, established in 1944 by the American Association of Textile Chemists and Colorists (AATCC), honors exceptional achievements in textile chemistry and related fields. It recognizes significant contributions to the development of chemical processes and agents in textile manufacturing. Open to all AATCC members for nominations, the award emphasizes the importance of innovation and public recognition in advancing textile sciences, a legacy of its founder, Dr. Louis Atwell Olney.