Best Large Grants for Nonprofit Organizations in Missouri

The Tommy Wilson Memorial Grant, established by Dr. George T. Wilson and his wife Irene, honors their son Tommy, who had cerebral palsy. This grant supports recreational programs for individuals with disabilities and aims to positively impact their lives. Applicants must be nonprofit organizations with a successful history of programming for individuals with disabilities. The grant prioritizes programs serving economically disadvantaged individuals and may only fund applicants once every five years.

The All of Us Research Program seeks to advance its mission by enabling access to biospecimens stored in the All of Us supported Biobank for researchers to conduct assays to evaluate associations between biomarkers and chronic diseases and add data to the All of Us resource for broad use by researchers. Biomarker analysis includes, but is not limited to, biomarker discovery; biomarker validation; novel disease stratification; and multiomics integration for disease risk, diagnosis, and prognosis, in support of advancing precision medicine. The All of Us Research Program is a historic effort to enroll 1 million participants who share data to accelerate research and medical breakthroughs, and enable individualized prevention, treatment, and care. Researchers use data from the program to learn more about how individual differences in lifestyle, environment, and genetics can influence health and disease.Grant authorities that allow the All of Us Research Program to forecast this opportunity are as follows: 42 USC 241 and 284.

The AWG Mid-Career Excellence Award honors outstanding mid-career women scientists contributing significantly to geosciences. It recognizes achievements across academia, industry, and government, with nominees evaluated on their scientific impact and community service. This prestigious award encourages nominations from the AWG membership and the broader geoscience community, fostering recognition of women's vital contributions in the field. With a commitment to diversity, the award aims to inspire future generations of women in geoscience careers.

The CHEERS Open Period 2 initiative invites white papers from researchers in various technical fields, focusing on projects that align with the objectives of the Continuing Enabling, Enhancing, Restoring, and Sustaining (CHEERS) MAA. This funding opportunity, backed by the US DOD's Air Force Materiel Command, is aimed at advancing national defense capabilities through innovative research and development in areas such as ordnance, telecommunications, and medical supplies.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Ronald Clark McDaniel Memorial Scholarship Fund

To honor the life and legacy of Ronald Clark "Ron" McDaniel, family and friends established the Ronald Clark McDaniel Memorial Scholarship Fund in 2008. Ron, born in Harlan, Kentucky, moved to Battle Creek, Michigan at the age of 5. He was involved in the National Honor Society, Boys State, played baseball and football and graduated in the top ten of his class at Pennfield High School. He then served in the United States Air Force obtaining presidential awards and honors before he made his home back in Battle Creek. Ron managed to balance his commitment and love for his family and sports while exhibiting an unequaled work ethic, often working 7 days a week, at the same company for 38 years. This fund was established to carry on his value of education. He believed that all young adults should participate in extra-curricular activities in or outside of school while focusing on education. Most of all Ron McDaniel believed education was the key to success. Scholarships in memory of Ron will be awarded to graduating seniors who have participated in high school athletics and are seeking educational opportunities in teaching/education.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Jeanette Elmer Scholarship

This opportunity is provided to honor the life and legacy of Jeanette Elmer.

The purpose of the Jeanette Elmer Scholarship program is to provide financial assistance to eligible American Indian and Alaska Native graduate students pursuing degrees full-time at an accredited institution in library science.

This opportunity is a need-based award.

The Air Force Fiscal Year 2027 Young Investigator Program (YIP) is designed to support early career scientists and engineers who have recently obtained their Ph.D. This initiative aims to promote innovative basic research in science and engineering while enhancing the professional growth of promising investigators. Awards are available to U.S. institutions where the principal investigator is a full-time employee. Eligible candidates must be U.S. citizens, nationals, or permanent residents.

The Brice and Teresa Moczygemba Engineering Scholarship Fund, established by the San Antonio Area Foundation, supports students pursuing a Bachelor's degree in Civil Engineering from accredited programs in the U.S. Eligible applicants include current high school seniors and college students residing in Bexar, Karnes, or Wilson counties, with a minimum GPA of 3.6. This renewable scholarship covers tuition, fees, books, and educational expenses, reinforcing the Foundation's commitment to enhancing community well-being.

The Ray Y Gildea Jr Award, provided by the Royal Geographical Society, offers grants of up to £1,000 to support innovative teaching methods in higher and secondary education. This endowed award aims to enhance geography education by funding projects that develop, research, or pilot new approaches, ultimately benefiting students directly. Eligible applicants must be actively teaching in the higher education or secondary school sectors in the UK or USA.

The OpenAI A People-First AI Fund supports U.S.-based nonprofits with 501(c)(3) status, focusing on AI literacy, community innovation, and economic opportunity. It aims to enhance public understanding of AI, promote participatory design in AI applications by communities, and expand access to meaningful work through inclusive practices. Organizations at all stages of AI adoption are encouraged to apply, especially those addressing the needs of traditionally marginalized populations. This initiative emphasizes equitable distribution of AI benefits.

Self-Defense Grants for MMIR Day

Facilitators, educators, organizers — May 5th is the Day of Awareness for Missing & Murdered Indigenous Women, Girls and Relatives. In honor of that day, we are offering mini grants to host a self-defense workshop for Indigenous girls and gender-expansive youth.

Why self-defense?

• Native women are murdered at 10x the national rate
• 84% experience violence in their lifetime
• Over 5,700 Native girls go missing each year

We also name the invisible crisis:

• Indigenous people from Mexico & Central America (Maya, Nahua, Zapotec, Mixtec, Lenca, and others) living in the U.S. face detention, deportation, and disappearances that are rarely counted in MMIR data.
• When a Tzotzil 18 year old like Royer Perez Jimenez dies in ICE custody, the silence is deafening.

Self-defense must include all Indigenous relatives.

XCNC has:

• $500 mini grants for stipends, space, supplies, and translation.

What we ask:

• Plan a workshop between May 5–31, 2026, rooted in community care.

The Edward C. Roy Jr. Award for Excellence in K-8 Earth Science Teaching, established by the American Geosciences Institute, honors educators who demonstrate exceptional leadership in earth science education. This prestigious award includes a $2500 prize for the winning teacher and a $1500 grant to attend the National Science Teaching Association's annual conference. The award celebrates the legacy of Dr. Edward C. Roy Jr., promoting innovation and excellence in teaching for future generations.

The Outstanding Earth Science Teacher (OEST) Award recognizes exceptional K-12 educators for their contributions to Earth Science education. Established in 1971 by the National Association of Geoscience Teachers, the award aims to stimulate interest in Earth Sciences among students. Eight national finalists are chosen annually, ensuring broad recognition and encouraging teaching excellence. Nominees can apply themselves or be nominated by colleagues, allowing for two awards in an educator's career to honor both early and late career achievements.

The Warren Alpert Foundation aims to enhance public health by funding medical research, education, and basic human services. With grants under $25,000, it supports initiatives that advance medical treatments and health education. The foundation is committed to fostering innovative research and solutions in healthcare, making a significant impact on community health and well-being.

The Ken W. Davis Foundation Grant provides essential funding to nonprofit organizations in the U.S. that align with the Foundation's mission of promoting basic human needs and education in line with Constitutional freedoms. With a minimum grant size of $2,500, the Foundation focuses on supporting human service organizations in Tarrant County, Texas, and the Permian Basin of West Texas and Southeast New Mexico, while also offering national support for grants related to Constitutional freedoms.

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Excellence in Medicine Awards- Dr. Edmond and Rima Cabbabe Dedication to the Profession Award

Honors physicians who are committed to expanding knowledge through teaching, conducting research and publishing. Other qualifying virtues include leadership, volunteerism and philanthropic activities in medical and other civic organizations.

Made possible by Edmond Cabbabe, MD, and Rima Cabbabe

The Eleanor Campbell Charitable Fund offers competitive scholarships to high school seniors and current college students from the Deering, Hillsborough, and Weare areas. With a history of over $900,000 awarded, the fund emphasizes academic achievement, financial need, and community involvement. Scholarships are available for full-time post-secondary education, with the potential for renewal based on continued eligibility. Announcements of winners occur during high school graduation ceremonies, ensuring recognition of their hard work and dedication.

Excellence in Medicine Awards

The AMA Foundation’s Excellence in Medicine Awards honor physicians and medical advocates who exemplify the highest values of the profession—volunteerism, community engagement, leadership, and service to underserved populations. Each recipient is recognized at a ceremony during the AMA Annual Meeting in Chicago and receives a $2,500 grant honorarium directed to a nonprofit health organization of their choice. Since 2005, more than 100 honorees have been celebrated through this program, with over $250,000 awarded to strengthen community health and advance equitable care nationwide. 

Excellence in Medicine Awards- Dr. Debasish Mridha Spirit of Medicine Award

Recognizes the work of U.S. physicians who demonstrate altruism, compassion, integrity, leadership and personal sacrifice while providing quality health care to destitute, distressed or marginalized populations in impoverished communities.

Made possible by Debasish Mridha, MD

The AWWA Scholarship Program, specifically the Neptune Technology Group Scholarship, offers a $5,000 award to undergraduate students pursuing degrees in mechanical, electrical, computer, or software engineering. This initiative, supported by the American Water Works Association, highlights the importance of investing in the future workforce of the water industry, fostering education and innovation among aspiring professionals.

The Safety, Security, and Privacy for Open-Source Ecosystems (Safe-OSE) program, launched by the National Science Foundation (NSF), addresses vulnerabilities in open-source products and their development infrastructure. It invites proposals to enhance safety, security, and privacy across various types of open-source ecosystems. The program aims to support initiatives that improve resilience against risks, attacks, and breaches, ensuring that OSEs can effectively manage current and future challenges.

Better World Scholarship Fund

The scholarship encourages women to acquire a degree in a science, technology, engineering, or math (STEM) field. The donor’s bachelor’s degree is in mathematics, followed 15 years later with a master’s degree in business administration. Her degree in mathematics provided opportunities for jobs in software development and application, medical research, technical documentation, organizational education and training, scientific research, and business. Her career was challenging, dynamic, encouraged creativity, never boring, offered schedule flexibility that allowed her to parent her four children, provided career choice independence, and was lucrative. Go STEM Girls!

Award Amount:

• Minimum $1,000

The HFM Foodservice Scholarship Fund supports students in Hawaii pursuing education in Culinary Arts or Agriculture. Applicants must demonstrate financial need, maintain a minimum GPA of 2.7, and attend an accredited institution in the U.S. Preference is given to prior recipients in good academic standing. This scholarship aims to empower future leaders in the foodservice industry by providing financial assistance to deserving candidates.

The Louisville Institute offers the Grant for Researchers to support academic research in North American Christianity and related fields. Grants of up to $55,000 are available for sabbatical leaves, research projects, and necessary resources. This flexible program combines previous grants to meet contemporary academic needs. Applicants can apply individually or as teams of up to three, provided they are based in the U.S. or Canada. Projects bridging scholarship and church life are of particular interest.

The Robanna Fund, established in 1992 by Robert and Deanna Levy, supports students pursuing careers in healthcare. Administered by the Hawai‘i Community Foundation, the fund awards scholarships averaging $6,000, depending on various factors such as the number of qualified applicants and donor preferences. Eligible applicants must maintain a minimum GPA of 2.0, reside in Hawai‘i, intend to major in a health-related field, and demonstrate financial need. This initiative aims to cultivate future healthcare professionals in the community.

The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.

The Robert C. Seamans, Jr. Fellowship in Science, Technology, and Public Policy at Harvard Kennedy School supports students excelling in research and management at the intersection of technology and public policy. This fellowship fosters future leadership in these critical areas, ensuring a commitment to addressing pressing public challenges. Applicants from diverse backgrounds are encouraged, as the program is designed to promote inclusivity and recognizes the importance of varied perspectives in policy-making.

The Classroom Research Grant PK-6, offered by the National Council of Teachers of Mathematics, aims to foster collaborative research between teachers and mathematics educators in Pre-K-6 classrooms. This grant supports innovative projects focusing on curriculum development, instructional methods for diverse learners, and technology integration in mathematics education. Successful proposals should lead to publishable research articles that demonstrate a significant impact on student learning outcomes.