Best Large Grants for Nonprofit Organizations in Missouri

The Ann W. Dooley Advancement Scholarship supports individuals aged 18-25 with intellectual disabilities who reside in Boone, Ogle, Stephenson, or Winnebago County. This scholarship encourages empowerment through education, enabling recipients to enhance their life skills for employment and independence. Established in memory of Ann Dooley, a dedicated educator, this scholarship honors her legacy of service and commitment to helping others. Applicants must provide verification of their disability and enrollment in a post-secondary program.

The Down Syndrome – Aim High Scholarship, offered by The Community Foundation for the Greater Capital Region, empowers students pursuing careers in special education or therapy for individuals with Down Syndrome. This scholarship supports dedicated individuals committed to improving the lives of others through education and professional development. Since 1968, the foundation has focused on enhancing community well-being, making this scholarship a vital resource for aspiring professionals in the field.

The FY26 Tick-Borne Disease Research Program (TBDRP) Idea Development Award aims to fund innovative research that enhances understanding and treatment of Lyme disease and other tick-borne diseases. The program encourages creative approaches that challenge existing paradigms and fosters impactful discoveries. A special career development option is available for early-career investigators, offering mentorship and a tailored review process to support significant research advancements.

The Robert Silman Award, presented biennially by the James Marston Fitch Charitable Foundation, recognizes innovative proposals in the preservation, restoration, or adaptive reuse of the built environment. Open to professionals in various design fields, the award encourages originality and practical applications that advance preservation in the U.S. With a funding limit of $15,000, it seeks projects that demonstrate a clear plan for dissemination and positive community impact, especially for underrepresented groups.

The Policy Campaign Grants by the Deaconess Foundation empower organizations to drive systemic change through policy advocacy and grassroots efforts. With funding up to $100,000, these grants aim to support urgent campaigns that enhance voter engagement and community organizing. By strengthening local movements, the foundation seeks to address racial and structural inequities in Eastern Missouri and Southern Illinois, fostering a path towards liberation and community well-being.

The Elizabeth Furber Scholarship honors the legacy of Elizabeth Furber by providing financial assistance to American Indian and Alaska Native female graduate students. This scholarship supports students pursuing full-time degrees in various fields, including fine arts, music, and creative writing. As a need-based award, it requires applicants to demonstrate Tribal affiliation through a Tribal Eligibility Certificate. This opportunity empowers eligible students to achieve their academic goals.

The Emergency/Medical Workers Behavioral Health Fund aims to support emergency workers facing trauma and anxiety due to their roles. Established by the HealthWell Foundation, it provides financial assistance for treatment-related costs, including copayments for prescription drugs, counseling, and transportation. In 2024, the Foundation awarded over $1.2 billion to underinsured patients, ensuring no one is denied essential healthcare due to financial barriers. This initiative helps address the critical mental health needs of those who serve on the front lines.

The Zero Hunger | Zero Waste Foundation Grant supports nonprofit organizations focused on ending hunger and reducing food waste. Since its inception, the foundation has allocated over $59 million to enhance food security through innovative programs and community engagement. Eligible applicants include 501(c)(3) nonprofits addressing critical needs such as food access, nutrition education, and support for vulnerable populations. This initiative aims to create equitable food systems and ensure that no one goes hungry.

The Patterson Family Foundation offers Chronic Disease Prevention, Screening, and Education Grants aimed at community initiatives that enhance health management. This funding supports programs that increase awareness of chronic conditions, promote healthy behaviors, and provide access to screening and education in rural areas. Projects must demonstrate community impact and readiness for implementation, focusing on early detection and long-term health improvement for residents in Kansas and western Missouri.

The Hazen and Sawyer Scholarship, valued at $10,000, is awarded annually to a graduate-level candidate dedicated to addressing critical challenges in drinking water, water reuse, and water resources. Sponsored by the American Water Works Association (AWWA), this scholarship supports students who are permanent residents of the U.S., Mexico, or Canada. Eligible funds cover tuition, books, and related educational expenses, enhancing the recipient's ability to contribute to the water industry.

The Centers for Structural Biology of HIV and Other Infectious Diseases aims to support innovative frontier science research that establishes new technologies and methodologies to provide insight into the mechanisms of hostpathogen interactions, as well as translational research to inform the development of novel and/or improved preventive interventions, therapeutics, diagnostics, and curative interventions across a broad spectrum of infectious diseases. These Centers focus on understanding the dynamics of molecular complexes, with the intention of informing mechanistically based discovery and/or design of interventions for the prevention, treatment, and cure of HIV and other infectious diseases. The goal is to facilitate the discovery of new therapeutic targets, new classes of interventions ranging from diagnostics, to small molecules and protein therapeutics, to neutralizing antibodies, and novel vaccine candidates, including nanoparticle vaccines, elucidate the mechanisms of action of interventions, and to determine the structural basis for interventional failures, but not support end-to-end preclinical development.

Of particular interest are the components of infectious agents and/or hosts for which sufficiently complete structureshave yet to be determined, including macromolecular complexes of proteins, nucleic acids, carbohydrates, lipid membranes, and/or small molecules. The Centers will be responsible for the validation of structural data using biological, biochemical, and computational methods and artificial intelligence (AI) models to help understand the biological mechanisms and structure-function relationships of these complexes.

This funding opportunity from the Patient-Centered Outcomes Research Institute aims to enhance health decision-making through comparative clinical effectiveness research, focusing on critical areas such as cancer, maternal health, and mental health. The initiative encourages robust observational studies that utilize existing data to derive patient-centered insights. Applications must address specific themes approved by PCORI and demonstrate potential benefits to the U.S. healthcare system, thus ensuring relevance and stakeholder engagement in research efforts.

About Us

The Community Mental Health Fund makes grants to 501(c)(3) mental healthcare organizations. We are a public fund and services are audited. Care must meet standards set by the Board of Trustees and the State of Missouri. We also support multi-agency initiatives, including cultural competence and trauma-informed care. Services assist our community’s most vulnerable citizens. Abused children, battered women, and homeless families are among those we serve.

Our Mission

Our Mission is to support a network of quality mental health services for persons with mental illness that are equitably accessible and responsive to the varied and unique needs of Jackson County Missouri residents.

2027 Fee-for-Service Applications

CMHF request for 2027 funding proposals

The Board of Trustees requests mental health fee-for-service funding applications from agencies currently funded in these funding categories:

• Safety Net
• Children's Treatment Centers
• Community-Based Mental Health
• Families and Children
• Domestic and Sexual Violence
• Support Services

The MPPEP Phase 3 program aims to enhance processing capabilities for invasive, wild-caught catfish, benefiting both processors and fishers. By increasing processing capacity and volume, the initiative seeks to create fair wages and stable job opportunities, fostering economic growth in rural areas. This grant will support innovative strategies that ensure sustainable practices and elevate incomes within the community, thus contributing to the overall development of the meat and poultry sector.

The J.R. Simplot Company Foundation Grant supports U.S. non-profit organizations focused on art, education, youth, community, and global food and agriculture. Established in 1929, the foundation is committed to enhancing community welfare through creative cultural endeavors, educational initiatives, health services, and youth programs. Applications are reviewed quarterly, ensuring a timely response to organizations dedicated to making a positive impact in their communities.

The Paul L. Busch Award, provided by the Water Research Foundation, honors individuals for innovative research in water quality. This prestigious award supports promising researchers with a $100,000 grant to advance their work. The selection process is inclusive, with no restrictions based on race, gender, or nationality, and encourages applications from diverse candidates. Recipients are expected to collaborate with U.S.-based organizations, fostering practical applications of their research in the water environment.

The Jeanette Zaichkin NRP Nursing Grant for Excellence and Innovation in NRP Education supports nurses dedicated to enhancing neonatal resuscitation training. This grant, offered by the American Academy of Pediatrics, provides up to $10,000 for innovative projects addressing key gaps in transitional physiology and evidence-based practices. Eligible applicants must be current NRP Instructors and work in neonatal care settings. The initiative aims to empower nurses in teaching essential skills for successful newborn resuscitation.

The WaterSMART Cooperative Watershed Management Program offers funding to eligible entities for developing local solutions to water management issues. This initiative supports watershed group development, restoration planning, and project design, promoting stakeholder cooperation and improving water reliability. It aligns with key priorities from the Trump administration, addressing complex water challenges and enhancing federal grant oversight. By facilitating these efforts, the program aims to stretch limited water resources and foster collaborative solutions among diverse stakeholders.

The GLS Campus Suicide Prevention program aims to enhance behavioral health services for college students, addressing critical issues such as suicide, depression, and substance use disorders. By fostering a culture of help-seeking and reducing stigma, this initiative ensures that at-risk students receive timely intervention and support. The program represents a vital investment in the mental well-being of students, promoting a healthier campus environment through evidence-based strategies and comprehensive public health approaches.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 300 funds and approximately $80 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Highland Orchestra Scholarship

Use the chart below to see which scholarships are the best fit for you! You must complete the Legacy Universal Application to apply.

Scholarship eligibility requires students to attend an accredited 2 or 4 year public or private institution of higher learning. All scholarships are for full-time students, unless otherwise noted. Renewable awards are for 4 years of undergraduate study and cannot be used for post graduate coursework; all awards are paid directly to the school or may be used for book reimbursement.

The Confluence Grant Program, initiated by the Conservation Alliance in 2021, aims to strengthen partnerships with historically racially excluded groups. It awards four grants of $100,000 over two years to support projects that protect or restore natural places. The program emphasizes building meaningful relationships and sharing resources, ensuring that funded projects center on solutions led by impacted communities. By fostering collaboration and addressing funding gaps, the program enhances the conservation landscape for diverse voices.

About Foam Recycling

The process to recycle foam is like that of other recyclables. In the case of foam products, a special compactor – called a “densifier” – may be used in the processing of the material. Foam products are over 90% air, so densifying it allows the material to be transported more cost-effectively. To give you an example, a 48-foot truckload of baled foam polystyrene weighs only around 16,000 pounds, whereas a truckload of densified foam polystyrene weighs 40,000 pounds.

Innovative alternatives are being developed and deployed that are categorized as chemical recycling (vs. mechanical recycling). This will take the plastic resin back to its base state – in the case of foam PS, back to a styrene monomer. With chemical recycling, increased organic contamination will only impact the amount of foam for recovery (yield), but will not impact the recyclability of the plastic.

Foam Recycling Coalition Grant Program

Funding Source: Funding for the grant program comes from contributions from members of the Foam Recycling Coalition, a special interest group of the Foodservice Packaging Institute.

Grant Amounts: Funding amounts will be made on a case-by-case basis and will be dependent on equipment needs. The maximum amount per grant is $50,000.

Cash Match: No cash match is required, but additional costs by the grantee may be incurred for related items such as site preparation, provision of conveying system and electrical infrastructure, freight, and other installation costs.

The US Dept. of Health & Human Services, through the Eunice Kennedy Shriver National Institute of Child Health and Human Development, is set to announce a funding opportunity focused on HIV research for pediatric and maternal populations. This initiative aims to foster innovative clinical trials addressing critical research areas in HIV, inviting collaborations from experts in various fields. Applications are not currently solicited, but potential applicants are encouraged to prepare for this opportunity.

The Carl and Marilynn Thoma Foundation offers Special Project Funding to support innovative initiatives in the arts, particularly in under-resourced areas. This grant encourages collaborative projects that enhance community engagement and education, focusing on art exhibitions and scholarships in the greater Texas Panhandle. By fostering leadership and creativity, the Foundation aims to empower individuals and organizations to make a lasting impact in the fields of art and art history.

The Pierce's Disease and Glassy-winged Sharpshooter Board offers grants to support research and outreach aimed at safeguarding California vineyards from serious pests and diseases. Prior funding has varied from $4,300 to $383,000, with projects typically lasting one to three years. Emphasis is placed on solutions that effectively address pest issues, encouraging multi-disciplinary teams to enhance the impact of their work on winegrape health.

The H. Hovnanian Family Foundation Grant supports the Armenian community in Armenia and the U.S., focusing on Monmouth and Ocean Counties, New Jersey. The Foundation prioritizes education, healthcare, arts, and youth development through grants to registered non-profits. Proposals should demonstrate sustainability and community impact, with favorable consideration given to projects that engage local stakeholders and foster collaboration. Applications are accepted year-round, with a maximum funding limit of $10,000 for operational expenses.

The Alpha Gamma Delta Foundation provides grants aimed at combating hunger in the U.S. and Canada, focusing on direct food assistance, food rescue, and nutrition education. Eligible organizations can receive up to $10,000 in funding, with an average grant size of $5,000. Since its inception, the Foundation has awarded over $2 million to support local food programs, ensuring communities have access to essential resources and assistance for those in need.