Best Seed Grants for Nonprofits in Missouri

QBE Foundation Inc.

The QBE Foundation’s focus is on creating strong, resilient and inclusive communities. We work in partnership with community organizations, working in climate resilience and inclusion – two areas where we believe we can have the greatest impact.

The QBE Foundation is one component that reflects our company’s focus, involvement, and investment in the neighborhoods where we do business, and where our employees live and work. The QBE Foundation also empowers our employees to volunteer with colleagues and community partners to make a difference for those in need. Employees can also coordinate fundraisers that are matched by the foundation.

QBE Foundation Local Grant Program

This program supports high-impact, community-based initiatives aligned to our focus on climate resilience and inclusion.

• Climate Resilience:
  • Helping communities prepare for, adapt to, and recover from climate-related risks, including preparedness, financial resilience, and risk reduction solutions.
• Inclusion:
  • Expanding access to opportunity for underserved communities through economic inclusion, workforce pathways, and removing systemic barriers.

Multiple grants of $30,000 will be awarded across our two focus areas.

The Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant, provided by the National Scleroderma Foundation, aims to support research in scleroderma-related lung disease. With a funding amount of $200,000, the grant encourages established investigators to explore innovative solutions and enhance understanding of this condition, ultimately working towards improving the quality of life for affected individuals and advancing medical knowledge in the field.

The Alzheimer’s Association's Center for Dementia Respite Innovation Grant (CDRI) supports innovative respite care projects, aiming to improve person-centered dementia care across the U.S. With up to $20 million available over five years, the grant encourages local respite care providers to enhance their services through collaboration and innovative solutions. Recipients will receive training and assistance to ensure their programs are effective and sustainable, addressing the growing need for quality dementia care.

The NMDP Barbara Buchbinder Nurse Research Program Grant supports pediatric BMT nurses conducting research to enhance transplant experiences and outcomes for children. With only 4% of federal funding allocated to childhood cancer, this program, honoring a dedicated nurse, aims to attract new talent to the field. Each selected Buchbinder Scholar receives a $25,000 award to pursue relevant investigations, emphasizing the importance of supportive care in pediatric allogeneic hematopoietic cell transplants.

The 1890 Scholarships Program, overseen by the USDA's National Institute of Food and Agriculture (NIFA), aims to enhance the recruitment and retention of undergraduate and graduate students at 1890 Land-grant institutions. It supports students pursuing degrees in food and agricultural sciences, fostering a skilled workforce in this critical sector. By providing scholarships, the program encourages academic excellence and commitment to the agricultural field, ultimately contributing to the development of future leaders in food systems.

The Eastern Bird Banding Association is offering the Memorial Fund Research Grants to support research utilizing avian marking techniques, such as banding. Applicants must submit a detailed project proposal, including significance and budget, alongside their background in ornithology. Grants are open to all, particularly encouraging student applications, with no lifetime award limit per individual. Projects must focus on species within EBBA territory, ensuring marking techniques are integral to the research.

About

A History Of Making Waves

Carnival Foundation oversees the many philanthropic endeavors of Carnival Corporation as well as its employee-driven service group, the “Friends Uniting Neighbors” (F.U.N.) Team.

Carnival Foundation’s contributions are widespread, touching the communities where the brands visit and operate. From the cities where our brands are headquartered to ports we visit around the world, we endeavor to make a difference to the lives of many.

Through monetary and in-kind donations, innovative philanthropic programs, employee fundraisers and hands-on volunteer initiatives, Carnival Foundation and the brands of Carnival Corporation support a variety of organizations. Whether it’s providing meals to the homeless and abuse prevention or working toward medical advancement and educating youth, Carnival Foundation’s reach is communitywide.

Grants Or Sponsorships

To apply for a grant or sponsorship from Carnival Foundation, prospective applicants must complete an online application and include the following information and documents:

• A letter of request with a brief description of the organization, including its legal name, history, activities, purpose and governing board
• Purpose for which the grant is requested
• Grant amount requested
• Listing of other sources of financial support
• Operating budget of the project for which the funds are requested
• Organization’s annual budget
• Copy of the organization’s most recent audited financial statement
• Copy of organization’s most recent 990 filed with the Internal Revenue Service
• Copy of Internal Revenue Service determination letter indicating 501© (3) tax-exempt status as an organization that is not a private foundation
• Organization’s completed W-9 form
• Geographical area(s) served
• Organizations applying for a grant renewal must submit a final report detailing use of the prior grant award. Interim and final reports will be submitted through our online portal.

About

A History Of Making Waves

Carnival Foundation oversees the many philanthropic endeavors of Carnival Corporation as well as its employee-driven service group, the “Friends Uniting Neighbors” (F.U.N.) Team.

Carnival Foundation’s contributions are widespread, touching the communities where the brands visit and operate. From the cities where our brands are headquartered to ports we visit around the world, we endeavor to make a difference to the lives of many.

Through monetary and in-kind donations, innovative philanthropic programs, employee fundraisers and hands-on volunteer initiatives, Carnival Foundation and the brands of Carnival Corporation support a variety of organizations. Whether it’s providing meals to the homeless and abuse prevention or working toward medical advancement and educating youth, Carnival Foundation’s reach is communitywide.

In-Kind Donations

To apply for an in-kind donation from Carnival Foundation, submit an online application complete with the following information:

• A letter of request with a brief description of the organization including its legal name, history, activities, purpose and governing board
• Contact name and information, including phone number and address for the individual who is organizing the event
• Name and date of the event
• Average amount of funds raised from the auction in previous years and estimated number and demographics of the event audience
• Description of how funds raised from the donation will be used within the organization
• List of other cruise suppliers, if any, participating in the event
• An outline with details of Carnival’s publicity/promotional opportunities associated with the event
• Copy of Internal Revenue Service determination letter indicating 501© (3) tax-exempt status as an organization that is not a private foundation.
• Copy of organization’s most recent 990 filed with the Internal Revenue Service
• Geographical area(s) served

The Atlantic Salmon Federation Olin Fellowships support individuals aiming to enhance their knowledge and skills in salmon conservation and management. These fellowships are available annually for various pursuits, including research and graduate studies, without the requirement of being enrolled in a degree program. Eligible applicants must be legal residents of the U.S. or Canada, and the fellowships can be conducted at accredited institutions or active management programs.

The Melanoma Established Investigator Award offers up to $125,000 annually for two years, aimed at established melanoma researchers or senior researchers transitioning into melanoma research. Eligible applicants include Associate Professors or higher, with both tenured and non-tenured faculty encouraged to apply. U.S. citizenship is not a requirement for this funding opportunity provided by the Melanoma Research Foundation.

The MRFBC Young Investigator Team Award supports innovative research in immuno-oncology for melanoma, offering up to $150,000 annually for two years. This funding targets U.S.-based researchers aiming to enhance clinical outcomes for melanoma patients or deepen the scientific understanding of immuno-oncology. The MRF collaborates with key institutions to address challenges in melanoma research, fostering partnerships that maximize research potential and impact.

The NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44) invites small businesses to submit applications for investigator-initiated clinical trials. This program particularly supports high-risk, hypothesis-driven studies that may involve non-routine interventions or unlicensed products. Letters of Intent are encouraged and due 30 days prior to the full proposal deadline. All applications must be submitted by 5:00 PM local time of the applicant organization.

The Tribal Transportation Safety Strategy Pilot Program, funded by the Office of the Assistant Secretary for Research and Technology, aims to address high traffic fatality rates among American Indian and Alaska Native populations. With a $2 million budget over three years, the program will create a university-led consortium to develop a strategic safety plan using artificial intelligence for risk analysis, culminating in a pilot project that showcases effective safety infrastructure in a Tribal community.

The National Institute of Mental Health is inviting research applications for the AIDS Research Center program, which includes Developmental Centers and full Research Centers. This initiative aims to enhance interdisciplinary HIV/AIDS research through collaboration and innovative approaches across various scientific domains. The program emphasizes alignment with national strategies and encourages applications from teams skilled in fostering partnerships with diverse stakeholders. Although applications are currently not being solicited, this notice allows potential applicants time to prepare strong proposals.

The TJX Foundation Grants support nonprofit organizations located within 15 miles of a TJX store that align with their community mission. Eligible areas include basic needs, education for at-risk youth, workforce training, and safety from domestic violence. Organizations must be a registered 501(c)(3) for at least 12 months and have a nondiscrimination policy. Applications are invited through a Letter of Inquiry, with funding decisions based on community impact.

The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.

The Cardiovascular & Pulmonary Research Grants aim to support impactful research that enhances cardiovascular and pulmonary health through physical therapy interventions. This grant emphasizes studies that assess patient characteristics, improve health outcomes, and address disparities. Research proposals must align with the 2023 APTA Research Agenda and prioritize clinical relevance, employing various investigative designs. The goal is to foster innovative approaches that significantly reduce cardiovascular disease risks and improve patient care in the U.S.

The Limited Competition NOFO aims to provide ongoing support for specific pathogen-free (SPF) macaque colonies that facilitate vital HIV/AIDS research. Only recipients funded under previous ORIP-supported SPF colony announcements are eligible to apply. These breeding colonies are crucial for maintaining SPF macaques, which are free from certain viruses that could jeopardize research outcomes. The project emphasizes the genetic characterization of macaques to enhance understanding of immune responses related to HIV and SIV.

The OVW Fiscal Year 2026 Tribal Sexual Assault Services Program provides crucial support to Indian Tribes and organizations in addressing sexual assault through intervention and advocacy. This program aims to assist victims of all ages, including youth and children, as well as their families and those affected by the trauma, except for perpetrators. Applications must be submitted by September 3, 2026, at 4:59 PM ET in JustGrants.

The Hearing Health Foundation's Emerging Research Grants (ERG) program supports innovative research in hearing and balance, providing up to $50,000 per year for promising projects. Since 1958, it has fostered early-career researchers and led to significant advancements in the field. Eligible applicants must be affiliated with U.S. institutions and hold relevant advanced degrees. The program emphasizes underfunded areas and encourages applications that expand knowledge and research capabilities in hearing health.

This funding opportunity aims to advance HIV/AIDS research by implementing human new approach methodologies (NAMs) to reduce the reliance on specific pathogen free (SPF) animal models. It emphasizes the integration of NAMs-enabled frameworks for in vitro testing while supporting essential SPF colony resources. The initiative seeks to enhance research rigor and reproducibility through innovative strategies that prioritize human-relevant models, ultimately improving HIV research outcomes and facilitating collaborative development in the field.

The Friends Foundation for the Aging Grant supports innovative and impactful programs aimed at addressing the needs of older adults, particularly within underserved populations. This Quaker foundation prioritizes collaboration and sustainability in its funding efforts. Eligible applicants must be 501(c)(3) public charities focused on enhancing the quality of life for aging individuals. Grants are typically awarded for one year and target organizations that align with the foundation's mission and values.

The Lead-Safe and Healthy Homes Financing Demonstration aims to allocate approximately $10 million for a National Fund Manager to create a national platform that pools public and private capital. This initiative seeks to reduce residential lead exposure, particularly for children, and enhance housing-related health conditions in low-income communities. By leveraging public funds and encouraging private investments, the fund will support local financing programs addressing lead-safe and healthy homes activities effectively.

The Store-Based Giving Program by Ross Stores Foundation supports socioeconomically disadvantaged youth by providing gift cards for school or professional clothing. Organizations must be federal tax-exempt and serve at least 60% low-income youth. Eligible programs include academic achievement and life skills initiatives. Award amounts typically range from $300 to $500, depending on budget and mission alignment. Applications are not accepted from organizations that have received donations within the past 12 months.

The Lead Hazard Reduction Grant Program aims to protect children under six from lead poisoning by funding comprehensive programs that identify and control lead-based paint hazards in eligible housing. This initiative supports states, Native American Tribes, and local governments to undertake necessary actions. Additionally, Healthy Homes Supplemental funding is available to address other health-related housing hazards, ensuring a holistic approach to occupant safety in homes affected by lead hazards.