South Carolina Infrastructure Funding via Appalachian Regional Commission
State and local agencies, local governing boards, nonprofits, tribes, and higher education institutions in eligible Appalachian counties in South Carolina can apply for Appalachian Regional Commission’s Area Development grants to fund critical infrastructure and workforce initiatives. Awards support projects like water and wastewater systems, transportation, broadband, entrepreneurship, worker training, and other business and human capital development efforts.
Appalachian Regional Commission
Workforce Development Grants for Nonprofits from Triangle Community Foundation
South Carolina and regional nonprofits offering education, workforce development, youth enrichment, or community well-being programs can access funding through Triangle Community Foundation’s Clancy & Theys 1949 Fund. Grants up to US $10,000 support initiatives that deliver measurable, lasting community impact, including job readiness, youth programming, and access to healthcare, housing, and essential social services.
Triangle Community Foundation
Creag Foundation Innovation Grants in South Carolina
Nonprofit 501(c)(3) organizations with innovative human services or social problem-solving programs in South Carolina can seek funding to develop or expand their work. Focused on fresh approaches to societal issues, the Creag Foundation invites smaller or evolving organizations to inquire about support, which may include workforce preparation and job readiness initiatives.
Creag Foundation
Youth Development Funding for Nonprofits from Dan Paul Foundation
501(c)(3) nonprofits supporting youth development, education, or welfare, including in South Carolina, can apply for the Dan Paul Foundation’s grants of up to US $15,000 for programs serving children and young people. Funding may support early childhood development, scholarships, child advocacy, homelessness and poverty services, refugee enrichment, and related youth-focused initiatives worldwide.
The Dan Paul Foundation
South Carolina Workforce Funding via Duke Energy Foundation
Nonprofit 501(c)(3) organizations and government entities in South Carolina can seek up to US $20,000 for workforce development, economic mobility, and related community programs. Grants from Duke Energy Foundation help workforce preparation and job readiness initiatives, especially those tied to the energy economy and underserved communities, on a rolling basis in eligible counties.
The Duke Energy Foundation
Workforce Development Funding from Cisco Systems
Nonprofit and nongovernmental organizations using technology for workforce preparation, job readiness, and economic empowerment projects in South Carolina and worldwide can apply for Cisco Systems Foundation’s Global Impact Cash Grants, with awards up to US $100,000. Grants support innovative, early-stage solutions serving mostly economically underserved communities in crisis response, education, economic empowerment, and climate resilience.
Cisco Systems Foundation
Workforce and Community Grants for Nonprofits from State Farm Companies Foundation
South Carolina workforce and job readiness organizations, schools, government programs, and eligible nonprofits can access funding for safety, education, and community development initiatives. Grants from State Farm Companies Foundation support efforts like job training, financial literacy, STEM and K–12 education, affordable housing, disaster preparedness, and community revitalization across the U.S.
State Farm Companies Foundation
William Randolph Hearst Foundation Culture Grants in South Carolina
South Carolina cultural nonprofits offering arts or science programming can access funding through the William Randolph Hearst Foundation for program, capital, and limited general or endowment support. U.S.-based 501(c)(3) institutions such as museums, theaters, symphonies, ballets, and arts schools that serve broad audiences may be eligible, including initiatives that build skills relevant to workforce preparation.
William Randolph Hearst Foundation
South Carolina Community Health Funding via Labcorp
South Carolina nonprofits and other eligible charitable organizations can receive funding for health, education, and community programs that improve people’s well-being. Labcorp Charitable Foundation provides support for initiatives such as healthcare access for underserved populations, STEM education, food pantries, and healthy lifestyle programs, which may include workforce preparation and job readiness components.
Labcorp Charitable Foundation
Workforce Development Grants for South Carolina Health
Healthcare divisions and community organizations in South Carolina’s Spartanburg, Cherokee, Union, and Greenville counties can apply for Spartanburg Regional Healthcare System Foundation grants to support workforce development and related health initiatives. Funding prioritizes projects improving community health, including behavioral health, maternal health, adolescents, and uninsured or underinsured populations in partnership with Spartanburg Regional Healthcare System.
The Spartanburg Regional Healthcare System Foundation
South Carolina Human Services Funding via Gupta Family Foundation
Applications due Jul 31, 2026
Nonprofit organizations helping disadvantaged people become self-reliant can seek US $5,000 - US $250,000 for human and social services, poverty alleviation, disability support, or disaster relief, including work in South Carolina. With a mission to expand opportunity, Gupta Family Foundation provides smaller 501(c)(3)s and qualifying foreign entities with annual or multi-year grants that may support workforce preparation and job readiness efforts.
Gupta Family Foundation
Truist Foundation Support for Workforce Programs
Applications due Aug 7, 2026
Nonprofit 501(c)(3) organizations providing workforce preparation, job readiness, and career pathways programming for adult workers can apply for US $10,000 - US $250,000 in Inspire Awards funding. Truist Foundation provides South Carolina and other eligible state nonprofits with support for training, upskilling, AI literacy, wraparound services, and career navigation in the evolving AI-driven economy.
Truist Foundation Inc
Blue Cross Foundation Support for Health Programs
Letter of inquiry due Aug 7, 2026
South Carolina health-focused nonprofits, government agencies, and tax-exempt educational or research institutions can seek funding to improve health outcomes and expand access to care, especially for economically vulnerable residents. South Carolina workforce and job-readiness programs that address oral health, mental health, or broader community health needs may be eligible for support from Blue Cross and Blue Shield of South Carolina Foundation.
Blue Cross and Blue Shield of South Carolina Foundation
Hansen Family Foundation Workforce Grants in South Carolina
Applications due Sep 11, 2026
South Carolina 501(c)(3) nonprofits offering workforce preparation, education, or related services can access funding through Hansen Family Foundation for programs that advance life, liberty, and the pursuit of happiness. Grants of US $1,000 - US $10,000 support work with children, education, humanitarian needs, and other community-focused initiatives; organizations must have budgets under $1 million and overhead below 25%.
Hansen Family Foundation
Education and Workforce Grants for South Carolina Orgs from South Carolina Student Loan
Applications due Oct 1, 2026
Organizations and academic institutions improving education, career readiness, or workforce development for South Carolina residents can apply for South Carolina Student Loan’s Power: Ed Grant, awarding US $25,000 - US $100,000 for programs serving middle school students through adults. Workforce preparation and job readiness initiatives in South Carolina may be especially competitive.
South Carolina Student Loan
South Carolina Community Funding via Georgia-Pacific Foundation
Applications due Oct 31, 2026
Nonprofit 501(c)(3) organizations, public schools, and qualified local government entities within 30 miles of a Georgia-Pacific manufacturing community in South Carolina can apply for Georgia-Pacific Foundation’s grants to support education, entrepreneurship, community enrichment, and environmental initiatives. Workforce preparation and job readiness programs that fit these focus areas and serve GP communities may be eligible.
Georgia-Pacific Foundation
Youth Workforce Readiness Funding for Nonprofits from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations providing workforce readiness training for at-risk youth near South Carolina TJX locations can seek support for job readiness and related services. The TJX Foundation also funds programs addressing basic needs, academic enrichment, and safety from domestic violence for vulnerable families and children within 15 miles of a TJX store, distribution center, or office.
The Tjx Foundation Inc
American Honda Motor Manufacturing Workforce Grants in South Carolina
Applications due Nov 1, 2026
South Carolina workforce and job-readiness programs focused on manufacturing careers can apply for funding to train a future-ready workforce, including technical skills, data analytics, and automation. Focused on manufacturing workforce development, American Honda Motor invites U.S.-based 501(c)(3) organizations and eligible schools serving Honda communities to request US $25,000 - US $100,000 for hands-on education initiatives.
American Honda Motor Co., Inc.
Max and Victoria Dreyfus Foundation Grants for South Carolina Workforce Programs
Applications due Nov 11, 2026
Max and Victoria Dreyfus Foundation provides South Carolina workforce preparation and job readiness nonprofits with US $1,000 - US $20,000 to support training, education, and related community programs. IRS-qualified U.S. organizations, including those serving youth, seniors, and people with disabilities, may be eligible if a relatively small grant would make a significant impact.
Max and Victoria Dreyfus Foundation
Dr Scholl Foundation Grants for Workforce Programs
Letter of inquiry due Jan 31, 2027
Nonprofit 501(c)(3) organizations can seek project funding for education, social services, health care, civic and cultural, or environmental initiatives from the Dr Scholl Foundation. Grants from Dr Scholl Foundation help South Carolina workforce preparation and job readiness programs that fit these categories, with awards ranging from US $5,000 - US $25,000.
Dr Scholl Foundation
Chick Fil A Foundation Grants for South Carolina Youth Programs
Applications due May 1, 2027
South Carolina workforce preparation and job readiness nonprofits serving underserved youth and families can access funding for education, leadership development, housing, food security, and environmental stewardship projects. Through the True Inspiration Awards, Chick Fil A Foundation offers US $30,000 - US $350,000 to 501(c)(3) organizations in the U.S., plus equivalent charities in Canada, the United Kingdom, and Singapore.
Chick Fil A Foundation Inc
US $850,000 - US $1,000,000
South Carolina Department of Education Charter Grants for South Carolina Schools
Applications due May 8, 2027
New or early-stage charter schools in South Carolina can seek funding to plan, launch, and initially operate high-quality public charter schools, with awards ranging from US $850,000 - US $1,000,000. The South Carolina Department of Education supports planning, curriculum, materials, equipment, professional development, and outreach, prioritizing strong models that address achievement gaps and underserved students.
South Carolina Department of Education
South Carolina Housing Innovation Funding via Enterprise
Applications due May 16, 2027
South Carolina workforce and housing organizations with ready-to-scale affordable housing innovations can seek US $2,000,000 grants to expand proven models. South Carolina workforce preparation programs that improve housing access may be eligible for Enterprise Community Partners’ national Housing Affordability Breakthrough Challenge, which supports design and construction, finance, and service delivery solutions for low- and moderate-income residents.
Enterprise Community Partners Inc
US $500,000 - US $3,000,000
Rural Health System Funding from South Carolina Department of Health and Human Services
Applications due Jun 1, 2027
State government agencies in South Carolina can access funding to strengthen rural health care systems, including facility improvements and workforce training. South Carolina Department of Health and Human Services provides US $500,000 - US $3,000,000 awards to support operational and financial resilience, which may benefit workforce preparation and job readiness efforts within rural healthcare settings.
South Carolina Department of Health and Human Services
South Carolina Department of Education Support for Workforce Education
Applications due Jun 30, 2027
Public school districts and schools in South Carolina can seek funding to pilot innovative programs that boost student achievement and readiness for college, careers, the military, and civic life. Grants from South Carolina Department of Education may benefit workforce preparation efforts through applied learning, workforce development, STEM/STEAM, literacy, and closing achievement gaps, especially in high-poverty, low-achieving schools.
South Carolina Department of Education
Community Partnership Funding for Nonprofits from Mutual of America Foundation
Applications due Jul 1, 2027
Nonprofit organizations in South Carolina with strong, replicable community partnerships can apply for Mutual of America Foundation’s national Community Partnership Award, recognizing collaborations that measurably improve lives. U.S. nonprofits addressing significant social issues through equal public, private, or social sector partnerships may be honored for leadership, impact, and scalable models of community building.
Mutual Of America Foundation
Frances P. Bunnelle Foundation Workforce Grants
Letter of inquiry due Jul 18, 2027
Eligible 501(c)(3) charities, houses of worship, government entities, and fiscally sponsored programs in South Carolina can apply for Frances P. Bunnelle Foundation’s fall Grants for the Common Good, awarding US $2,500 - US $15,000 for general operating or special projects. Georgetown County organizations focused on workforce preparation, poverty, basic needs, or environmental preservation may benefit.
Frances P. Bunnelle Foundation