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Best Large Grants for Nonprofit Organizations in New York

Find the perfect Large Grants for Nonprofit Organizations in New York on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in New York in the United States.

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$2.80B

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$5K

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10,000+ grants
$2.80B total
$5K median

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AWWA Scholarship Program - Woodard & Curran Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $5,000
The AWWA Scholarship Program, specifically the Woodard & Curran Scholarship, offers a $5,000 merit-based award annually to undergraduate or graduate students focused on water-related fields. This initiative aims to support historically marginalized communities, including women and BIPOC students, promoting equity in the water industry. With clean water being essential for community health, this scholarship reflects AWWA's commitment to nurturing the next generation of water professionals.
Water Resource Management Environment Academic Scholarship Programs

Black Giving Collective Grant

Rochester Area Community Foundation
Private
Genesee County, New York, Livingston County, New York +6 more
US $5,000 - US $15,000
The Black Giving Collective (BGC) champions Black-led initiatives in the eight-county region of Rochester, New York, addressing systemic disparities within the Black community. Guided by the 2024 State of Black Rochester report, BGC provides grants ranging from $5,000 to $15,000, focusing on program support, capacity building, technology, and community engagement. Organizations must have Black leadership or membership to apply, ensuring that funding directly impacts and uplifts the community.
Black American Services Black American Culture & Heritage Economic Services & Development +5 more

Fair Housing Initiatives Program - Education and Outreach Initiative (362880)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
American Samoa, Guam +4 more
US $175,000 - US $2,500,000
The Fair Housing Initiatives Program (FHIP), established by Congress in 1988, aims to fund organizations to combat discriminatory housing practices. The Education and Outreach Initiative (EOI) educates stakeholders about their rights under fair housing laws. Key components include the National Media Campaign, which promotes fair housing awareness nationally, and local programs that support community-based outreach. HUD oversees the process, ensuring compliance and monitoring of funded initiatives to enhance fair housing practices.
Basic Human Needs Real Estate & Housing Equitable & Affordable Housing +1 more

Kalamazoo Valley Chapter - George L. Disborough TU Research Grant Fund

Trout Unlimited, Inc.
Private
Caribbean, Mexico +1 more
Up to US $2,500
The Kalamazoo Valley Chapter's George L. Disborough TU Research Grant Fund, established in 1990, aims to support graduate-level research on trout habitat and conservation projects aligned with Trout Unlimited's mission. This fund seeks innovative studies on coldwater salmonids and their environments, with a preference for projects conducted in Michigan. It is open to U.S. citizens or permanent residents enrolled in accredited institutions, promoting efforts that enhance the quality of aquatic resources.
Ichthyology (Fish) Fisheries Freshwater Conservation

Teams to Promote Aging in Place in OMH Supportive Housing (TPAP) Grant

New York State Office of Mental Health
State/Local Government
Allegany County, New York, Broome County, New York +42 more
US $300,000 - US $1,500,000

Teams to Promote Aging in Place in OMH Supportive Housing (TPAP) 

Request for Proposals

The purpose of “Teams to Promote Aging in Place in OMH Supportive Housing or TPAP” Geriatric Demonstration Project is to facilitate supportive housing residents aging in place based on their priorities and preferences who are age 55 years and older, as well as residents younger than 55 years living with complex medical conditions that necessitate homecare. Older adults living in OMH supportive housing are at risk of losing community tenure due to emerging unmet care coordination, cross service system navigation, and homecare needs compounded by lack of connection to social determinants of health (SDOH) resources, and community and natural supports. Grant funding will support an enhanced home care rate, provision of at least one paid peer professional, and enhanced care coordination with the local office for aging and community partners that addresses social determinants of health and social engagement needs. OMH supportive housing residents identified as at risk for losing community tenure will be supported by an interdisciplinary care team of (1) an OMH supportive housing case manager, (2) a local office for aging case manager, (3) a homecare professional, and (4) at least one mental health or substance use/gambling peer professional who will collaborate with the residents to identify outstanding service and social needs. This will build a person-centered, holistic plan that is based on the older adult’s priorities and preferences for aging in place. A peer professional in this RFP is defined as a person certified, or provisionally certified, as a mental health Peer Specialist through the New York Peer Specialist Certification Board or a person certified, or provisionally certified, as a substance use/gambling Recovery Peer Advocate through the New York Certification Board. Grantees will also be required to collaborate with community-based organizations across service systems, including mental health, aging, substance use, and gambling harms, that also address social determinants of health and social engagement needs, such as, but not limited to, Social Care Networks, Rural Health Networks, Cornell Cooperative Extension, Older Adult Rural Support Program, Regional Economic Development Councils, or Downtown Revitalization Initiatives. This may include projects focused on community inclusion, the Dwyer Veterans Peer-to-Peer Support Program, club houses, OASAS and OMH recovery centers, older adult centers, faith-based, civic, arts, cultural organizations, etc. To foster sharing of best practices in meeting the holistic needs of OMH supportive housing residents, grantees and their partners will participate in virtual and in-person learning collaboratives that include crossdisciplinary training curriculum consisting of trainings chosen in consultation with the chosen grantees and the Geriatric Interagency Mental Health Substance Use Disorder Planning Council and the Master Plan for Aging advisory groups.

Wrap around funding will be available to provide services and goods not covered through existing reimbursement channels that support aging in place in OMH supportive housing. Examples include, but are not limited to, non-medical transportation, memberships to community groups and/or gyms, continuing education, supplies to support personal interests and hobbies, large print calendars, pill containers, and mobility aids. Wrap-around funding can also be used to provide technological support based on the residents’ needs and preferences. Examples include equipment (laptops, computers, personal devices, and/or internet access), online communities and devices to support engagement (Virtual Senior Centers, GetSetUp, Discover Live interactive virtual tours, animatronic pets, and online support through self-help and peer support groups), and technology literacy classes (for email, video chats with friends, children, grandchildren, etc., banking, patient portals, and education on fraud protection) are additional supports to help people use technology to age in place.

This RFP can be used to expand or enhance existing aging programs in OMH supportive housing or can be used to develop a new program that meets all the program requirements. OMH CR-SROs awarded the “Aging in Place Pilot” grant MH253015 may also apply for this grant for their supportive housing programs.

All types of proposals will be evaluated using the same criteria and applicants must identify the geographic designation they will serve, rural or non-rural. Rural counties in NYS are listed in the table below.

Aging / Gerontology Supportive Housing & Shelters Health Disparities & Social Determinants of Health +2 more

Biogen General Grants

Biogen Foundation Inc.
Corporate
United States
Unspecified amount

Biogen General Grants

Funding to support a project or program that does not fit any of the other defined grant categories.

Biosimilars Neurological Diseases & Disorders Musculoskeletal Diseases +2 more

Kaiser Permanente Center for Gun Violence Research and Education Grant Program

Kaiser Permanente Advisory Services
Private
United States
Up to US $300,000
The Kaiser Permanente Center for Gun Violence Research and Education Grant Program aims to transform the landscape of gun violence research and education by funding initiatives that address community firearm violence and suicide. This program focuses on partnering with affected communities, integrating healthcare approaches, and providing substantial funding to enhance research capacity and intervention effectiveness. With funding available in two categories, the initiative seeks to promote evidence-based solutions that foster community healing and well-being.
Gun Violence Prevention Suicide Prevention

Robert and Joan Dircks Foundation Grant Program

Robert & Joan Dircks Foundation
Private
United States
US $1,000 - US $15,000
The Robert and Joan Dircks Foundation Grant Program supports non-profit organizations in New Jersey that provide opportunities for disadvantaged individuals. With grants ranging from $1,000 to $15,000, the foundation focuses on innovative programs that solve critical issues rather than operational needs. Eligible organizations must be tax-exempt under section 501(c)(3) of the Internal Revenue Code. The foundation does not fund political activities, cultural projects, or operating budgets, ensuring resources directly benefit those in need.
Children With Disabilities Poverty Alleviation & Services Disability Care & Services +3 more

The Alice M. Ditson Fund: Organizational Support - Spring Deadline

The Alice M. Ditson Fund
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Alice M. Ditson Fund provides organizational support for professional performing ensembles and institutions committed to advancing the work of younger and relatively unknown living American composers. Grants are available for general operating or project support, emphasizing contemporary American classical concert music. Eligibility includes organizations without non-profit status if sponsored by a 501(c)(3) entity, while projects featuring American music are prioritized. This funding opportunity encourages innovative performances and fosters greater recognition of emerging talents in the classical music sphere.
Classical Music Opera Dance

Bass Pro Shops Large Grant

Friends of Reservoirs
Private
United States
Up to US $100,000
The Friends of Reservoirs: Large Grant supports fish habitat enhancement projects in manmade reservoirs, promoting conservation and partnerships. With approximately $250,000 in Federal funding and $500,000 from Bass Pro Shops, grants up to $75,000 are available. Projects must match funding and can be multi-year, with specific caps on subsequent funding. This initiative aims to address habitat impairments and enrich community quality of life through improved fishing opportunities.
Habitat & Ecosystem Restoration Fisheries Freshwater Conservation +1 more

Friends of Reservoirs: Mossback Grant

Friends of Reservoirs
Private
United States
US $1,000
The Friends of Reservoirs: Mossback Grant offers three grants of $1,000 in Mossback products to eligible members of Friends of Reservoirs organizations. Sponsored by Mossback Fish Habitat, these grants aim to enhance structural habitat in public waters. The total retail value is approximately $1,500. Applicants must cover freight costs, and a $25 application fee applies to each submission. This initiative supports habitat restoration efforts across member organizations.
Habitat & Ecosystem Restoration Fisheries Freshwater Conservation

NAFC Capacity Fund

National Association of Free and Charitable Clinics Inc
Private
United States
US $20,000 - US $30,000

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Capacity Fund

The NAFC Capacity Fund supports investments that strengthen clinic and pharmacy infrastructure and organizational effectiveness. This funding is designed to help NAFC members build the systems, tools, and capabilities needed to operate more efficiently, improve quality, and expand their ability to serve patients over time.

Medical Education & Professional Training Telemedicine & Telehealth Health Facilities & Clinics +2 more

NIHCM: Research Grants

The National Institute for Health Care Management
Private
United States
US $50,000 - US $60,000
The NIHCM Foundation is seeking innovative research proposals that address critical issues in U.S. health care, particularly focusing on drug pricing, provider consolidation, health care delivery, chronic disease management, and the role of artificial intelligence. Projects should aim to improve affordability and quality of care. We welcome submissions from a variety of researchers and organizations, with a preference for studies that can be completed within one year.
Health Policy & Advocacy Health Care Access & Delivery Health Disparities & Social Determinants of Health +4 more

NIDA Research Education Program for Clinical Researchers and Clinicians (R25 Clinical Trial Not Allowed) (357168)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $350,000
The NIDA Research Education Program (R25) aims to enhance the training of a workforce skilled in biomedical, behavioral, and clinical research, particularly regarding substance use disorders. This program supports educational activities that prepare clinicians and clinical researchers. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the full proposal deadline. This initiative does not fund non-research-related clinical training.
Addiction & Substance Use Disorders Medical Education & Professional Training Drug Use Disorder

Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional) (358116)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The Limited Competition Small Grant Program for NIDDK K01/K08/K23/K25 recipients offers funding opportunities for pilot studies and feasibility research. This program aims to support researchers transitioning to independent investigator roles by providing resources for small projects that can yield preliminary data for future R01 applications. Key deadlines for applications range from February 2025 through January 2028, with specific dates for standard, renewal, and AIDS-related applications.
Diabetes Kidney Diseases Digestive System Health & Diseases

Watershed Association Professional Development Mini-Grants

Lake Champlain Basin Program
State/Local Government
Addison County, Vermont, Bennington County, Vermont +13 more
Up to US $500
The Watershed Association Professional Development Mini-Grants support staff and volunteers of watershed organizations in the Lake Champlain Basin. These grants cover costs for professional development activities aimed at enhancing water quality and organizational capacity. Eligible organizations include 501c3 nonprofits focused on water stewardship. Preference is given to those with previous LCBP contracts exceeding $4,000. Applications are accepted monthly, with awards announced shortly after deadlines.
Freshwater Conservation Water Resource Management

Live Más Scholarship

Taco Bell Foundation Inc
Private
United States
Unspecified amount
The Live Más Scholarship, offered by the Taco Bell Foundation, supports students aged 16-26 pursuing higher education and workforce readiness. Emphasizing passion and impact, applicants showcase how their interests drive positive change in their communities. The foundation is dedicated to breaking down educational barriers, fostering creativity across various fields including arts, technology, and entrepreneurship. This initiative empowers young dreamers to turn their aspirations into actionable goals, creating meaningful contributions to society.
Education - Higher Education Vocational & Trade Education Career / College Preparation +2 more

NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Not Allowed) (357995)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Not Allowed) invites proposals for high-risk, multi-center observational studies on diseases relevant to NIDDK's mission. Applicants are encouraged to consult with NIDDK staff and must complete planning activities before submission. Key deadlines for applications span from February 2025 to October 2026, with optional Letters of Intent due 30 days prior to full proposals.
Diabetes Kidney Diseases Digestive System Health & Diseases

Medication Therapy Management (MTM) Initiative Grant

National Association of Free and Charitable Clinics Inc
Private
United States
US $30,000

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

Medication Therapy Management (MTM) Initiative

The Medication Therapy Management (MTM) Initiative, supported by the McKesson Foundation and administered by the NAFC, aims to improve medication access, adherence, and patient understanding among uninsured and medically underserved populations. Individuals without health insurance often face significant barriers to obtaining prescription medications and receiving the counseling necessary to manage chronic conditions effectively. Through this initiative, NAFC will provide $30,000 grants to member free and charitable clinics and pharmacies to establish or expand Medication Therapy Management programs aligned with recommendations from the American Pharmacists Association. Funding will support activities such as staff certification in MTM, development of standardized protocols, and patient education to help individuals better understand their medications, manage side effects, and support overall treatment plans. By strengthening pharmacist-led care and improving communication between providers and patients, this initiative seeks to enhance medication adherence, improve chronic disease management, and advance better health outcomes for vulnerable patient populations.

Chronic Illnesses Patient Care & Services Health Care Access & Delivery +3 more

MMUF Dissertation Grant

Institute for Citizens & Scholars
Private
United States
Up to US $30,000
The MMUF Dissertation Grant, funded by the Mellon Foundation, supports doctoral candidates who are alumni of the Mellon Mays Undergraduate Fellowship. This grant aids scholars in completing their dissertations, ensuring diverse perspectives are represented in academia. With up to $30,000 for a 12-month period, the program encourages candidates to secure additional funding from their institutions. The initiative aims to bolster access to education and foster understanding among varied backgrounds, ultimately enhancing the academic landscape.
Humanities & Social Science Art & Culture Religion & Spirituality +11 more

NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional) (351679)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The NIDA Mentored Clinical Scientist Development Program Award aims to foster research independence in clinician scientists by providing intensive supervised research training and career development in the field of substance use and substance use disorder. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submission for this essential funding opportunity.
Addiction & Substance Use Disorders Medical Education & Professional Training Drug Use Disorder

The Affirm Cares Employee Foundation Grant

Affirm Cares
Private
American Samoa, Guam +4 more
Unspecified amount
The Affirm Cares Employee Foundation Grant, established by Affirm, aims to support non-profit organizations making a significant impact in financial literacy, community enrichment, and technology education. Grants range from $1,000 to $10,000, focusing on sustainable initiatives that empower communities and alleviate housing insecurity. Eligible applicants must be 501(c)(3) designated non-profits operating within the U.S. The foundation prioritizes measurable outcomes in its funding efforts, fostering civic engagement and vibrant communities.
Homelessness Services Civic Engagement & Education Financial Literacy +5 more

Melanoma Research Resident and Fellowship Grant

Melanoma Research Foundation
Private
United States
Up to US $10,000
The Melanoma Research Resident and Fellowship Grant offers $10,000 to support early-career residents and fellows in conducting clinical or laboratory research focused on melanoma. This grant encourages innovative approaches to understanding prevention, detection, and treatment of melanoma, including special emphasis on ocular melanoma. Eligible candidates must have a qualified mentor and conduct research at a U.S. institution. This initiative aims to enhance the landscape of melanoma research and foster the next generation of researchers.
Cancer / Oncology Skin Diseases & Dermatology Eye Diseases & Disorders +1 more

Rapid Response Opioid And Pain Management ECHO Funding Opportunity

Association of State and Territorial Health Officials (ASTHO)
Association/Society
American Samoa, Guam +4 more
Up to US $140,000
The Rapid Response Opioid and Pain Management ECHO Funding Opportunity by the Association of State and Territorial Health Officials (ASTHO) aims to enhance clinician training in effective pain management strategies. This initiative focuses on non-opioid treatments, substance use screening, and risk reduction counseling, promoting compassionate care while addressing public health challenges and ensuring continuity for patients affected by prescription disruptions. The program seeks to improve overall health outcomes and reduce risks associated with opioid use.
Drug Use Disorder Chronic / Acute Pain

William Brewster Memorial Award

American Ornithological Society
Association/Society
United States
Unspecified amount
The William Brewster Memorial Award, awarded by the American Ornithological Society, recognizes exemplary contributions to ornithological science through a significant body of work on Western Hemisphere birds published in the last decade. This prestigious award honors the legacy of William Brewster, a founding member of the American Ornithologists' Union, and includes a medal and honorarium funded by the William Brewster Memorial Fund. Nominations are open to all, fostering diversity in ornithology.
Ornithology Ornithological Conservation

Richard and Mary Myerly Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Richard and Mary Myerly Scholarship, offered by the Community Foundation of Washington County, MD, supports low-income students pursuing careers in photography or fine arts at accredited institutions. Established in memory of Richard and Mary Myerly, this scholarship invites applications from students in Washington County and surrounding areas, promoting educational opportunities and honoring community values. With over 100 scholarships available, this initiative aims to empower the next generation of artists and photographers.
Education - Higher Education Education - High School Academic Scholarship Programs +4 more

Large Grants for Nonprofit Organizations in New York Highlights

Looking for large grants for nonprofit organizations in New York?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in New York recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in New York

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Large Grants for Nonprofit Organizations in New York grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Large Grants for Nonprofit Organizations in New York over $25K in average grant size

100+ Large Grants for Nonprofit Organizations in New York over $50K in average grant size

38 Large Grants for Nonprofit Organizations in New York supporting general operating expenses

200+ Large Grants for Nonprofit Organizations in New York supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in New York?

Most grants are due in the third quarter.

Q1
26.5%
Q2
21.7%
Q3
27.4%
Q4
24.4%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in New York?

Grants are most commonly $52,500.

$300 $300 Min.
$52,500 $52.5 K Median
$870,598 $870.6 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for New York?

Grants are most commonly $123,825.

$123,825

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in New York year over year?

In 2024, funders in New York awarded a total of 270,645 grants.

2022 258,176

2023 259,835

2024 270,645

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in New York given out in New York, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in New York changing over time?

Funding has increased by 16.44%.

2022 $28,202,880,598

2023 $28,659,853,906
1.62%

2024 $33,370,589,734
16.44%

New York Counties That Receive the Most Funding

How does grant funding vary by county?

New York County, Kings County, and Nassau County receive the most funding.

County Total Grant Funding in 2024
New York County $21,403,401,202
Kings County $2,517,718,693
Nassau County $2,484,899,697
Tompkins County $2,194,408,740
Rockland County $1,906,062,935