Best Large Grants for Nonprofit Organizations in New York

The Lake Erie Environmental Justice Grant, awarded by the Ohio Lake Erie Commission, aims to support restoration projects in historically underserved communities within Ohio's Lake Erie watershed. Funded through the U.S. EPA’s Great Lakes Environmental Justice Grant Program, this initiative focuses on enhancing stormwater management, strengthening coastal resilience, and advancing environmental justice. With a significant grant of up to $750,000, OLEC collaborates with partners like Black Environmental Leaders and Rural Action to ensure equitable resource distribution and impactful outcomes.

The Les Mehrhoff Botanical Research Award, established by the New England Botanical Society, supports innovative botanical research that enhances our understanding of New England's flora. Open to applicants without membership, it prioritizes projects lacking traditional funding sources. Eligible expenses include fieldwork, lab supplies, and moderate stipends. This award encourages researchers to explore unconventional inquiries and fosters a deeper appreciation for the diverse plant life in northeastern North America.

What does this program do?

It provides loans and grants to Microenterprise Development Organizations (MDOs) to:

• To help microenterprises startup and growth through a Rural Microloan Revolving Fund.
• Provide training and technical assistance to microloan borrowers and micro entrepreneurs.

What is an eligible area?

• Rural areas outside a city or town with a population of fewer than 50,000 residents. Urbanized areas near a city of 50,000 or more may not be eligible.
• The borrower’s headquarters may be based within a larger city so long as the project service area is located in an eligible rural area.
• The lender may be located anywhere.

 What kind of funding is available? 

• Grants are available to provide technical assistance to rural micro-entrepreneurs or microenterprises, up to $205,000 annually. Funding at the requested level is not guaranteed, and at least 15 percent matching funds are required.
• Loans of $50,000 to $500,000 may be used for establishing a Rural Microloan Revolving Fund managed by the Microenterprise Development Organization.
• Total aggregate debt is capped at $2.5 million.

Microenterprise Development Organizations must demonstrate experience in managing a Revolving Loan Fund, or:

• Certify that it or its employees have received education and training from a qualified microenterprise development training entity so that the applicant has the capacity to manage such a revolving loan fund.
• Demonstrate that it is actively and successfully participating as an intermediary lender in good standing under the U.S. Small Business Administration (SBA) Microloan Program or other similar loan programs as determined by the Administrator.

What are the loan terms?

• Maximum term is 20 years.
• Two-year payment deferral.
• Must establish a loan loss reserve fund.

What terms are required on loans to ultimate recipients?

• Up to $50,000.
• Fixed interest rate.
• Limited to 75 percent of project cost.

How may the funds be used?

Microlenders may make microloans for qualified business activities and expenses including, but not limited to:

• Working capital.
• Debt refinancing.
• Purchasing equipment and supplies.
• Improving real estate.

The Mother Cabrini Health Foundation's Access to Healthcare Grant Program aims to enhance equitable access to healthcare across New York State. By addressing barriers faced by underserved populations, the foundation supports initiatives that ensure all individuals receive necessary health services. Grants typically begin at $75,000, focusing on direct service programs that align with the Catholic Church's ethical principles. This funding is crucial for organizations dedicated to improving healthcare outcomes for disadvantaged communities.

New York Department of State

The New York Department of State’s core mission is to provide a better quality of life and expand opportunities for all New Yorkers by fostering community revitalization, catalyzing economic growth through business formation, protecting consumers, helping new Americans, supporting local governments, assisting individuals and families to achieve upward economic mobility, and ensuring safety and integrity through the regulation of licensed occupations and the development of building standards and codes.

Community Resilience and Flood Risk Reduction Grants

The NYS Department of State (Department or DOS), through the Clean Water, Clean Air and Green Jobs Environmental Bond Act of 2022 (Bond Act), is soliciting applications from eligible applicants through the New York State Consolidated Funding Application (CFA) for Community Resilience and Flood Risk Reduction Grants. These grants will enhance community resilience and reduce flood risk through the implementation of the following project types:

• Coastal Rehabilitation and Resilience Projects
• Inland Flooding and Local Waterfront Revitalization Program (LWRP) Implementation Projects 

State assistance awarded and paid shall not exceed 90% of the total eligible project costs set forth in the application and as approved by the Department.

Community Resilience and Flood Risk Reduction Grant implementation projects may include completion of final design and construction, or construction-only for eligible projects. Projects should prioritize nature-based and natural solutions where feasible and provision of co-benefits. 

Coastal Rehabilitation and Resilience Projects

Coastal Rehabilitation and Resilience Projects align with the Coastal Zone Management Act of 19721; a federal law with the goal to guide development in a manner that preserves, protects, and where possible, restores or enhances the uses and resources of the nation’s coastal zone. The National Oceanic and Atmospheric Administration (NOAA) approved New York State’s Coastal Management Program (NYS CMP)2 in 1982, which provides a framework for federal and State agency decision-making for actions that have a reasonably foreseeable effect on the State’s coastal uses and resources. The State’s coastal area includes but is not limited to waters and lands bordering the St. Lawrence, Niagara, and Lower Hudson Rivers, the Great Lakes, Long Island Sound, and all tidal waters.3 DOS is the delegated state agency administrator of the NYS CMP, which implements the Coastal Zone Management Act on behalf of NOAA.

The Climate Justice Fellowship, funded by NYSERDA, invites organizations to host a full-time fellow for one year to advance climate justice and clean energy initiatives in Disadvantaged Communities. Eligible fellows, who must be NYS residents from Priority Populations, will receive a salary and professional development support. NYSERDA aims to fund approximately 150 fellowships by 2026, with a total budget of $6 million. Host employers must apply to confirm eligibility and facilitate fellows' projects.

Ending Epidemics Education, Training and Technical Assistance Services

The intent of this Request for Applications is to support a comprehensive statewide training initiative to strengthen the capacity of local public health agencies, hospitals, community-based organizations, healthcare providers, peer workers, educators, and other partners to improve outcomes for the AIDS Institute’s strategic health priorities. The goal is to reduce health inequities by implementing training and education interventions, such as in-person or virtual trainings, conferences, seminars, digital learning tools, and capacity building initiatives that will prepare providers with the knowledge and skills to mount an effective response to the syndemics of HIV, viral hepatitis, sexually transmitted infections, and substance use disorders. Building upon a foundation of health equity, other priorities for training include the health concerns of the LGBTQAI+ population, the concerns of persons living with HIV across the lifespan (noting the diversity in needs depending on age-related concerns), as well as training around legal and policy initiatives for these syndemic health issues and populations at risk. 

Ending Epidemics in New York State

In June 2014, NYS announced a three-point plan to end the AIDS epidemic in NYS.12 This plan provided a roadmap to significantly reduce HIV infections to a historic low by the end of 2020, with the goal of achieving the first ever decrease in HIV prevalence. The plan also aimed to improve the  health of all HIV positive New Yorkers and was the first jurisdictional effort of its kind in the U.S.

The three points highlighted in the plan are:

• Identify persons with HIV who remain undiagnosed and get them linked to care;
• Link and retain persons diagnosed with HIV in health care to maximize viral suppression;
• Increase access to Pre-Exposure Prophylaxis (PrEP) for persons who are HIV negative.

New York State has been laying groundwork for ending the AIDS epidemic since the disease emerged in the early 1980s. New York State’s response to the HIV/AIDS epidemic has involved the development of comprehensive service delivery systems that evolved over time in sync with the evolution of AIDS from a terminal illness to a manageable chronic disease. This strategy enabled the state to implement new technologies as they were introduced, including new treatments, new diagnostic tests and, more recently, PrEP (pre-exposure prophylaxis). Due to the historic and robust State response over the last 36 years, New York State has bent the curve on the HIV epidemic, reversing the decades-long increase in the number of people in New York State that are diagnosed with HIV. 

Available Funding

Up to $3,094,000 annually in New York State and HRI funding is available to support programs funded through this RFA (total of $15,470,000 in New York State and HRI funding for five (5) years). 

The External Collaborative Research (ECR) program by Boehringer Ingelheim invites academic and community scientists to propose collaborative studies aimed at protocol development and result publication. This program offers potential drug and financial support, excluding direct salary for the Principal Investigator. Budgets must represent fair market value and will be negotiated further. Research interests span therapeutic areas including Cardio-Renal-Metabolic, Mental Health, Dermatology, and Oncology, encouraging innovative solutions to unmet medical needs.

The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.

The Resilient and Connected Appalachians Grant Program, offered by The Nature Conservancy, provides up to $100,000 for projects that acquire land and easements throughout the Appalachian region. This program emphasizes equitable conservation, aiming to support historically marginalized communities and enhance access to nature while addressing climate change impacts. Projects must demonstrate community engagement and align with the program's goals to protect vital habitats and foster resilience in the face of environmental challenges.

New York Department of Transportation (NYCDOT)

It is the mission of NYSDOT to provide a safe, reliable, equitable, and resilient transportation system that connects communities, enhances quality of life, protects the environment, and supports the economic well-being of New York State.

Transportation Alternatives Program

Background

The New York State Department of Transportation (NYSDOT) is making available up to $97.4 million to support bicycle, pedestrian, multi-use path and active transportation-related projects and programs that support the goals of NYSDOT’s Transportation Master Plan 2050 and New York’s nation-leading Climate Leadership and Community Protection Act (CLCPA). Projects selected under this solicitation will support the Department’s commitment to community-centered transportation by providing safe, reliable, equitable and resilient transportation systems. Selected projects will also connect communities, enhance the quality of life, protect the environment, and support the economic wellbeing of New York State. These funds, made available to the State through the Federal Highway Administration (FHWA) and administered by NYSDOT, are provided through the Transportation Alternatives Program (TAP).

The National Sea Grant Law Center is inviting proposals for the Coastal Resilience Program to research laws and policies addressing coastal resilience challenges such as sea level rise and flooding. With a funding cap of $150,000 over two years, this initiative aims to assess the effectiveness of existing policies and promote informed decision-making in coastal management. Up to two projects will be selected for funding, supporting innovative solutions to enhance community resilience against environmental threats.

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

The Fred and Barbara Erb Family Foundation is dedicated to fostering a healthy Great Lakes ecosystem and a vibrant Southeast Michigan community. Since its inception, it has invested over $180 million in environmental, cultural, and educational initiatives. As it transitions to spend down its assets by 2034, the Foundation aims to make bold, impactful investments that address urgent community needs and promote sustainable development.

The Norfolk Southern In-Kind Donation Grant supports organizations seeking physical donations of materials that align with their focus areas, including safety, sustainability, workforce development, and thriving communities. This grant is available year-round, with no application deadline. Recipients must be located within Norfolk Southern territory and are encouraged to apply for resources that will enhance their community projects and initiatives, fostering growth and resilience.

The Giants Foundation Grant supports nonprofit organizations focused on community issues, health improvement, and youth empowerment. Established in 1993 by the New York Giants, the foundation aims to provide financial assistance to eligible organizations in the NY, NJ, and CT areas. Eligible applicants must be 501(c)(3) nonprofits and either youth organizations or those using funds for youth-related programming in health, education, fitness, or football. This grant fosters positive impacts in the community.

New York State Energy Research and Development Authority

The New York State Energy Research and Development Authority (NYSERDA) offers objective information and analysis, innovative programs, technical expertise, and support to help New Yorkers increase energy efficiency, save money, use renewable energy, and reduce reliance on fossil fuels. A public benefit corporation, NYSERDA has been advancing energy solutions and working to protect the environment since 1975.

Clean Energy Career Awareness Program: Teaching Resources & Educator Training

Description

The New York State Energy Research and Development Authority (NYSERDA) requests proposals from firms that will help advance a Clean Energy Career Awareness Program to serve New York State (NYS) students, youths, and teachers. Proposal will be considered by contractors who wish to provide workforce development and training services for either or both of the following Pillars:

• Pillar 1 - Clean Energy Teaching Resources: A web-based platform that contains freely accessible clean energy educational resources responsive to the needs of NYS students and teachers.
• Pillar 2 - Clean Energy Educator Training: Professional development opportunities for NYS educators to advance their understanding of clean energy in NYS.

For Pillar 1, NYSERDA seeks proposer with experience and expertise in clean energy, curriculum curation, and web design. The proposer shall develop webpage(s) that contain freely accessible clean energy educational resources that are responsive to the needs of NYS students and teachers. The proposer shall maintain the webpage(s) regularly to ensure accuracy and timeliness of resources.

For Pillar 2, NYSERDA seeks proposer with experience and expertise in both clean energy and professional development for educators. The proposer shall develop and deliver professional development opportunities for at least 2,000 unique NYS educators to advance their understanding of clean energy in NYS and remove the barriers to understanding the benefits of clean energy. The proposer shall ensure 50+% of participating educators serve and/or are from NYS Disadvantaged Communities (DAC) and/or Priority District Schools.   

A total of $5,750,000 is available, with $750,000 designated for Pillar 1 and $5,000,000 designated for Pillar 2.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

The Karen Colina Wilson Foundation Grant supports programs for children, youth, and women, enhancing their health and well-being through education, art, literature, and music. Established in 2006, the foundation aims to make a positive difference in their lives, particularly in Southern and Western Wayne County, Michigan. Grants typically range from $500 to $10,000, often as matching funds, fostering broader fundraising efforts by local nonprofit organizations.

The NYS Community Development Block Grant (CDBG) supports low- and moderate-income communities through funding for various activities such as public facilities, economic development, and community planning. Applications are accepted on a rolling basis, and compliance with public participation requirements is essential. The program aims to enhance housing opportunities and economic growth in smaller municipalities, providing technical assistance to ensure effective use of funds for community development.

New York State Homes and Community Renewal

HCR develops, preserves and protects affordable housing and invests in economically vibrant communities. We work with many private, public and nonprofit partners to create safe, healthy and affordable housing opportunities for all New Yorkers.

HCR is charged with carrying out Governor Hochul’s new $25 billion, five-year, comprehensive housing plan to increase housing supply by creating or preserving 100,000 affordable homes across New York including 10,000 with support services for vulnerable populations, plus the electrification of an additional 50,000 homes.

Community Development Block Grant

The NYS Community Development Block Grant or CDBG Program is a unique source of federal funding for Cities, Town, Villages, and Counties to assist low- and moderate-income communities, households, and people.

CDBG funding assistance can include everything from drinking water and sanitary sewer projects to grants for home repair, senior and community center improvements to grants to small business for start-up and expansion.

The NYS CDBG program provides financial assistance to eligible cities, towns, and villages with populations under 50,000 and counties with an area population under 200,000, in order to develop viable communities by providing decent, affordable housing, and suitable living environments, as well as expanding economic opportunities, principally for persons of low and moderate income. 

Expert technical assistance is always available to help your community apply for and administer CDBG funds, and to help direct assistance to where it is needed most.

Eligible Activities

CDBG funding may be used for eligible activities as outlined below. This is not intended to be an exhaustive list of eligible activities and applicants are encouraged to develop projects in response to local need that may not fit neatly in any one category. In these cases, applicants are encouraged to contact OCR for additional guidance prior to applying.

Funding is available for the following activities: 1) Public Facility; 2) Community Planning; 3) Economic Development - Stand-Alone Business Assistance; 4) Economic Development - Microenterprise Assistance; and 5) Imminent Threat.

Economic Development

CDBG funds may be used to assist a specific, stand-alone business or to assist a community to establish a microenterprise assistance program to support multiple businesses.

Microenterprise Assistance

Funding is provided to eligible communities to provide entrepreneurial training and financial assistance to forprofit businesses with five (5) or fewer employees, including the owner(s), for an identified CDBG eligible activity which will result in the creation or retention of permanent, private sector job opportunities, principally for persons from low-moderate income families. Businesses under this category may also meet HUD requirements if owned by a documented low to moderate income person.

The Long Island Sound Study Research Grant Program, managed by Connecticut Sea Grant and New York Sea Grant, aims to fund research that supports effective management of Long Island Sound's resources. The program prioritizes actionable research addressing anthropogenic stressors while enhancing ecosystem health. A 50% non-federal match is required for funding, ensuring collaboration and sustainability. Applicants are encouraged to align their proposals with the themes outlined in the Comprehensive Conservation and Management Plan, facilitating informed decision-making for the region's environmental future.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

The Champions in Action Grant, offered by the Citizens Charitable Foundation, supports nonprofit organizations in California, Massachusetts, New Jersey, New York City, Pennsylvania, Rhode Island, and Southern Florida. This funding, totaling $50,000, aims to empower nonprofits addressing social challenges through innovative solutions. With an application deadline extended to August 22, 2025, eligible organizations can gain not only financial support but also media coverage and volunteer assistance to enhance their community impact.

The Agriculture Energy Audit Program, offered by NYSERDA, assists eligible farms in New York with energy efficiency measures through no-cost energy audits conducted by Flexible Technical Assistance Consultants. This program supports various farm types, including dairies and greenhouses, and provides benchmarking reports for greenhouse facilities. By promoting energy efficiency, the program aims to help farmers save money and reduce fossil fuel dependence, contributing to environmental sustainability.

The Scherman Foundation's Democracy Program champions the empowerment of Black, Indigenous, and People of Color (BIPOC) communities. It focuses on enhancing civic engagement, safeguarding voting rights, and reforming democratic processes to ensure inclusivity and accountability. By supporting locally-rooted organizations in key states, the foundation aims to build a more equitable democracy where diverse voices are heard and political power is reclaimed by those historically marginalized. This program is pivotal for advancing racial justice and fostering systemic change.

The NHLBI Career Transition Award (K22) program supports postdoctoral fellows in transitioning their research to extramural institutions. The program includes a mentored intramural phase (up to two years) followed by an extramural phase (three years), totaling five years of support. Applications have multiple deadlines, including October 12, 2024, and February 12, 2025, among others. Successful transition depends on the awardee's progress during the mentored phase, evaluated by NHLBI.