Best Addiction and Substance Abuse Grants in North Carolina

The OJJDP FY 2026 Community and Schools Youth Drug Prevention Program aims to combat youth substance use through comprehensive prevention strategies. This initiative invites applications from states, local governments, and nonprofit organizations to develop programs that educate and support youth in schools and community settings. By fostering collaboration with law enforcement and community coalitions, the program seeks to build capacity and implement effective interventions to protect the well-being of American youth.

The BJA FY 2026 Tribal Justice Training and Technical Assistance Program aims to enhance Tribal justice systems through specialized technical support. This funding opportunity addresses critical issues such as violent crime and substance-use related crime, including opioids. By assisting federally recognized Indian Tribes, the program promotes the development of sustainable legal and corrections infrastructure while fostering collaboration with federal, state, and local partners. Applications are due by October 28, 2026, at 8:59 p.m. ET.

The MOORE Equity in Mental Health Community Grants Program, initiated by the American Psychiatric Association Foundation, aims to enhance mental health services for young people of color. With grants up to $10,000 over two years, it supports community organizations addressing mental health and substance use inequities. Eligible applicants include non-profits with a focus on culturally relevant care and sustainable solutions. The program fosters collaboration and awareness through innovative initiatives aimed at improving access to essential mental health services.

The Innovation in Behavioral Health (IBH) Model (the “Model”) is an eight-year, voluntary service delivery and payment model promoting integrated care in behavioral health (BH) settings. The IBH Model will test the impact of a value-based payment (VBP) model aligned across Medicaid and Medicare that supports an integrated care delivery framework in specialty BH organizations and settings for adult Medicaid, Medicare, and dually eligible beneficiaries with moderate to severe mental health conditions and/or substance use disorders (SUDs).The Centers for Medicare & Medicaid Services (CMS), through its Center for Medicare & Medicaid Innovation (Innovation Center), will select up to eight state Medicaid agencies (SMAs) to participate in the Model. Implementation will begin in January 2025 and end in December 2032. The Model will have an eight-year performance period, which will be comprised of a three-year Pre-Implementation Period along with a five-year Implementation Period. Up to $7.5 million dollars in cooperative agreement award funding will be available to each selected Recipient over the course of the eight years. 

The ASCAP Foundation Mariana & Paul Williams "Sunlight of the Spirit" Award supports organizations dedicated to addiction recovery through music. Established by the ASCAP Foundation and Paul Williams, the award recognizes efforts that improve lives affected by addiction. Eligible nominees must be 501(c)(3) organizations with a commitment to music-based recovery. The award includes a $5,000 prize to further their impactful work in the community, fostering healing through the therapeutic power of music.

The Academic Research Enhancement Award (AREA) supports small-scale research grants for institutions with limited NIH funding, emphasizing biomedical research experiences for undergraduates. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over the past seven years. This initiative aims to enhance the research environment at these institutions, fostering student involvement in research activities.

The NAILBA Charitable Foundation Grant aims to support small, well-managed U.S. charities that assist those in need, particularly children. Grants are available to organizations with backing from a NAILBA member and that meet specific criteria, such as nonsectarian operation and appropriate fiscal accountability. Since its inception in 2002, the foundation has invested in community transformation by funding initiatives that directly engage in beneficial services, thereby enhancing the welfare of underprivileged groups.

The Alvah H. and Wyline P. Chapman Foundation offers grants to support charitable, educational, and community-focused initiatives, primarily in Florida and Georgia. Eligible applicants must be IRS-recognized 501(c)(3) organizations. The foundation prioritizes projects that address children's welfare, education, multicultural understanding, substance abuse prevention, and homelessness. Grants typically do not exceed $15,000, and proposals must be endorsed by a Foundation Director. Interested parties should submit a Letter of Inquiry for consideration.

The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.

Agility Grants, initiated by the National Council on Problem Gambling, aim to minimize gambling-related harm through funding nonprofit organizations for innovative prevention programs. These grants focus on addressing gaps in services and enhancing existing initiatives. Eligible applicants include U.S.-based 501(c)(3) organizations, with priority given to projects targeting at-risk populations. The program emphasizes community impact and requires evaluations to assess effectiveness, fostering collaboration and awareness within diverse communities affected by gambling.

The APA Foundation's Helping Hands Grants provide up to $5,000 to medical schools for projects aimed at improving mental health education and assistance in under-served communities. Initiated in 2005, this program empowers medical students to lead initiatives that promote awareness of mental illness and encourage community service, particularly among minority populations. By partnering with community agencies, these projects foster a deeper interest in psychiatry while addressing critical mental health needs.

The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.

The Unifour Foundation Endowment Fund, established in 1998, supports qualified charitable organizations in Alexander, Burke, Caldwell, and Catawba counties. With over $3 million awarded since 1991, grants typically range from $5,000 to $10,000. The fund prioritizes projects addressing early childhood education, mental health, and community needs like housing and food insecurity. Eligible organizations include 501(c)(3) charities and local government units, with applications open to those serving the designated areas.

The Jennie K. Scaife Charitable Foundation Grant focuses on enhancing family support, women's and children's health, and animal welfare. It aims to fund programs that promote beneficial human-animal interactions and early intervention in addiction prevention. Eligible organizations must have a valid 501(c)(3) designation. Grants align with at least one of the foundation's focus areas, ensuring impactful contributions to community welfare and well-being.

The Elevance Health Foundation's Behavioral Health Grant aims to address significant challenges in mental health and substance use disorders. With a commitment of up to $90 million over three years, the Foundation seeks partnerships with nonprofits to enhance treatment access, promote prevention strategies, and alleviate loneliness among affected individuals. This initiative emphasizes innovative solutions and measurable outcomes, targeting both national and local programs, particularly in states with pressing health disparities.

The HEAL Initiative aims to address the complex interplay between chronic pain and opioid use disorder (OUD), affecting 40-60% of OUD patients. Through the IMPOWR initiative, this funding opportunity seeks to develop integrated care strategies that enhance treatment delivery at health systems levels. By identifying effective interventions and collaborative care models, the initiative strives to improve patient outcomes in managing both chronic pain and OUD, while emphasizing the roles of various healthcare professionals in this integrated approach.

FY25 Veterans Treatment Court Program

Executive Summary

This NOFO will support the implementation and enhancement of veterans treatment court (VTC) operations. VTCs connect veterans who come in contact with the justice system to treatment for substance use disorders (SUD), mental health disorders (MHD), co-occurring mental health and substance use disorders (MHSUD), post-traumatic stress disorder (PTSD), and traumatic brain injury (TBI). Funding supports service coordination, and recovery support services. VTCs integrate mandatory drug testing, incentives and sanctions, and transitional services in judicially supervised criminal court settings that have jurisdiction over veterans with behavioral health treatment needs. These courts aim to reduce recidivism and overdose fatalities, while increasing access to treatment and recovery support that leads to long-term recovery.

Category 1 supports the planning and implementation and/or launch of a VTC. These courts will support core capacity and provide critical behavioral health treatment, case management and coordinated judicial supervision, sanctions and incentives, and other supportive services, such as transitional housing, peer recovery services, relapse prevention and employment services, that can reduce recidivism.

Program Description

Planning and Implementation grants are available to eligible jurisdictions ready to commit to a 6- month planning phase followed by an implementation and/or launch of a VTC that supports core capacity and provides critical behavioral health treatment, case management and coordinated judicial supervision, sanctions and incentives, and other supportive services, such as transitional housing, peer recovery services, relapse prevention and employment services, that can reduce recidivism, including serving veterans who cannot or do not have access to Department of Veterans Affairs (VA) services

The ICRG Seed Grant supports innovative research aimed at understanding and treating gambling disorders. With a focus on pilot studies, secondary data analysis, and developing new methodologies, it encourages both established and early-career researchers to apply for funding up to $40,000. The grant emphasizes the importance of addressing critical issues in gambling research while ensuring the inclusion of diverse participant groups. This initiative aims to enhance public education and promote responsible gaming practices.

The NCRG Large Grant, provided by the International Center for Responsible Gaming, supports high-quality research on gambling disorders and responsible gambling. Eligible applicants can request up to $75,000 annually for a maximum of 24 months, totaling $187,500. The grant emphasizes scientific rigor through its advisory board, ensuring only the best proposals receive funding. This initiative aims to advance understanding and treatment of gambling-related issues through peer-reviewed research.

The Cabarrus County Community Foundation Grant Cycle aims to enhance local initiatives through competitive grantmaking. The Foundation prioritizes projects that address community needs in areas such as Arts & Culture, Education, Environment, Health, and Housing. Eligible organizations include 501(c)(3) nonprofits and educational institutions serving Cabarrus County residents. Note that applications for specific food-related programs will not be accepted this year, as the focus is on sustainable food options and nutrition.

The Patient-Centered Outcomes Research Institute (PCORI) will announce the Phased Large Awards for Comparative Effectiveness Research on December 2, 2025. This funding aims to support high-quality, patient-centered comparative clinical effectiveness research projects. The initiative encourages applicants to engage with patients and stakeholders to address critical healthcare dilemmas and improve decision-making. Projects should compare established clinical alternatives with evidence of efficacy, targeting vital health issues across diverse populations.

The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.

The Bernau Family Foundation Grant aims to enhance individual lives and foster positive leadership through funding initiatives that provide long-term solutions. Grants are awarded to IRS-designated public charities or nonprofits, emphasizing projects that promote civic responsibility, education, and mentor programs. The foundation prioritizes smaller organizations that encourage meaningful community engagement and constructive change, ensuring a lasting impact on society.

The John William Pope Foundation provides annual grants focusing on human services and the arts, primarily in North Carolina's Wake and Vance Counties. Established in 1986, the Foundation promotes self-reliance and community responsibility, funding initiatives that address critical social challenges. By prioritizing private resources over government funding, it fosters creative expression and supports nonprofits that empower individuals and families. The Foundation's mission is to ensure future generations have equal opportunities for success.

The Albert G. and Olive H. Schlink Foundation, established in 1966, has significantly impacted Ohio's nonprofit sector by increasing its annual grant distribution from an initial $500 to over $1.4 million in 2023. The Foundation prioritizes organizations with ties to Erie and Huron Counties and emphasizes thoughtful evaluation of all grant applications. With a focus on community needs, it continues to honor the founders' legacy while adapting to the evolving demands of local nonprofits.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.