Best Addiction and Substance Abuse Grants in North Carolina

Nonprofit and community organizations expanding substance use disorder prevention, treatment, services, or supports in North Carolina can apply for up to US $500,000 annually to address access gaps. North Carolina Department of Health and Human Services supports addiction and substance use disorders programs statewide through at least 12 contracts aimed at building an equitable system of care.

North Carolina nonprofits planning innovative arts or human services projects can apply for the Joy W. Pope Memorial Grant Funds, with awards from US $20,000 - US $100,000 for project-specific work. With a mission to foster innovation, John William Pope Foundation supports capital improvements, program development, equipment, and technology, including initiatives addressing addiction and substance use disorders.

Addiction and substance use researchers working with adult populations that experience health disparities can apply for National Institutes of Health funding to test SBIRT/P approaches. Grants from NIH help North Carolina and other U.S. teams evaluate screening, brief intervention, and referral to treatment or prevention in collaboration with healthcare and community partners.

Nonprofit 501(c)(3) organizations in North Carolina working on addiction and substance use disorders can seek project or capital support to improve prevention, treatment, and recovery services. Focused on education, healthcare/rehabilitation, and human and community services, the Philip L Van Every Foundation offers US $10,000 - US $50,000 for established programs with strong leadership and results.

North Carolina research institutions and healthcare or community partners working on addiction and substance use disorders can access funding through the National Institutes of Health to test SBIRT/P approaches for adults facing health disparities. Projects must prospectively evaluate screening, brief intervention, and referral to treatment or prevention for alcohol, tobacco, and other drug use.

Nonprofit and local government organizations working on addiction and substance use disorders, alcoholism, or drug use disorder can apply for funding, including those in North Carolina if they are Native American organizations. Focused on education, health, public safety, treatment, housing, and related services, the Confederated Tribes of Siletz Indians supports charitable programs across the U.S.

Grants from Amerihealth Caritas Foundation help North Carolina 501(c)(3) nonprofits run project-specific programs addressing addiction and substance use disorders, children’s mental health, and related trauma. Organizations with $300,000–$10 million in revenue that serve Medicaid-enrolled communities can apply for US $100,000 - US $150,000 to improve healing behaviors, health care access, and family empowerment.

The Drug-Free Communities (DFC) Support Program aims to foster collaboration among community coalitions to combat youth substance use. Established by the Drug-Free Communities Act of 1997, it encourages partnerships among various stakeholders, including governmental and non-profit agencies. The program focuses on reducing substance use among youth and promoting protective factors within communities. This funding opportunity is available for those who have completed the initial funding cycle or experienced funding interruptions, supporting their ongoing efforts to create a healthier environment for youth.

The Drug-Free Communities (DFC) Support Program, initiated by the Drug-Free Communities Act of 1997, aims to bolster community coalitions dedicated to preventing youth substance use. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this program focuses on collaboration among various stakeholders, including government and non-profit entities, to effectively reduce substance abuse among youth and promote protective factors within communities.

The HEAL Initiative's Career Development Awards aim to empower early career researchers and clinicians in implementation science. By providing training and funding, this initiative seeks to address substance use prevention and treatment through research projects that align with the HHS Overdose Prevention Strategy. Focused on vital areas such as opioid prescribing, OUD treatment, and recovery support, the program aspires to cultivate a new generation of experts who will significantly impact addiction clinical practices and mentorship.

The Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use initiative aims to enhance prevention services for infectious diseases among people who use drugs (PWUD). It encompasses two components: a biennial survey to assess service gaps and capacity, and increased support for testing and treatment services. The initiative seeks to improve data utilization in service provision, ultimately increasing testing for HBV, HCV, and HIV, and ensuring more PWUD engage in treatment and care.

This funding opportunity invites Small Business Technology Transfer (STTR) grant applications aimed at developing FDA-regulated medical products for patients with opioid and stimulant use disorders. Projects may focus on pharmacotherapeutics or diagnostic devices, including software. The initiative seeks to address the ongoing opioid crisis by supporting innovations that enhance treatment options for individuals and communities affected by these disorders.

The Opioid Crisis Response Program Fellowship, offered by Equal Justice Works, addresses the opioid epidemic by mobilizing public interest lawyers to provide vital civil legal aid to underserved communities affected by Opioid Use Disorder. This two-year fellowship enables attorney fellows to advocate for clients' rights, reduce barriers to treatment, and enhance community education about legal impacts. Through collaboration with various stakeholders, the program aims to improve health outcomes and foster systemic change in the fight against this public health crisis.

Universities, research institutions, and similar organizations focused on substance use and addiction can seek funding to provide skills-development courses and hands-on research experiences, including for North Carolina participants. Focused on building a diverse biomedical and behavioral science workforce, the National Institutes of Health offers up to US $1,250,000 for structured research education programs.

The National Cooperative Drug/Device Discovery/Development Groups (NCDDG) program invites applications to foster innovative research in treating mental disorders and substance use issues. This initiative promotes collaboration between academia and industry, supporting diverse, multidisciplinary projects aimed at developing rational therapies and neurostimulation techniques. Applicants are encouraged to submit Letters of Intent 30 days before the proposal deadline to enhance project alignment with funding goals.

Clinician-scientist training programs in addiction and substance use disorders in North Carolina can apply for institutional career development support, with awards up to US $750,000. Grants from the National Institutes of Health help eligible institutions provide intensive, supervised research training that advances substance use and substance use disorder research toward independent clinical research careers.

Research institutions and teams conducting HIV and substance use studies, including addiction and drug use disorders, can apply for up to US $1,500,000 in funding, including projects based in North Carolina. Focused on high-priority HIV research, the National Institutes of Health invites detailed proposals from basic, clinical, and implementation scientists working with people who use drugs.

The HEAL Initiative aims to combat the opioid crisis through action-oriented research that enhances the translation of addiction epidemiology, prevention, treatment, and recovery services into practice. It prioritizes scalable, evidence-based approaches targeting various levels, including individual and community. The initiative supports a range of methods for research deployment, emphasizing collaboration between researchers and decision-makers to improve outcomes for those affected by addiction and related chronic pain.

The NCDDG program supports innovative research aiming to discover and develop new treatments for mental disorders, including substance use and alcohol use disorders. This initiative encourages collaborations between academic and industry partners to advance neurostimulation techniques and drug/device development. Applicants are invited to submit proposals that focus on specific projects utilizing the U01 mechanism, with a clear emphasis on rationally designed candidate agents and cutting-edge technologies. Letters of Intent are encouraged 30 days prior to the submission deadline.

North Carolina research institutions and clinical trial teams focused on addiction and substance use disorders can access funding through the Food and Drug Administration to study analgesics, anesthetics, and addiction. Awards of US $2,000,000 support clinical trials, outcome measures, neurodevelopmental assessments, and evidence-based plans to improve prescribing for pain, anesthesia, and substance use disorders.

The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.

The NIDA Research Education Program (R25) aims to enhance the training of a workforce skilled in biomedical, behavioral, and clinical research, particularly regarding substance use disorders. This program supports educational activities that prepare clinicians and clinical researchers. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 30 days prior to the full proposal deadline. This initiative does not fund non-research-related clinical training.

The Tobacco, Alcohol, and Cannabis Policy Research for Health Equity grant aims to support research on policies affecting tobacco, alcohol, and cannabis use in the U.S. This initiative focuses on how these policies impact populations facing health disparities. Key components include engaging community organizations to advance equity in cancer prevention. Important deadlines for applications range from February 2025 to October 2027, providing opportunities for both standard and renewal submissions.

Research institutions studying addiction and substance use disorders in the U.S. and territories, including work relevant to North Carolina, can seek pilot or exploratory funding for time-sensitive substance use epidemiology and health services research. US Dept. of Health & Human Services: National Institutes of Health supports projects responding to sudden drug issues, policy shifts, and emerging clinical or justice system opportunities, awarding up to US $275,000.

Research institutions studying addiction and substance use policy can apply for NIH R21 funding of up to US $275,000 in the U.S., including North Carolina. Grants from the National Institutes of Health help organizations examine how tobacco, alcohol, and cannabis policies affect use, exposure, and health disparities to advance cancer prevention and health equity.

The National Institute on Drug Abuse (NIDA) is launching a specialized entrepreneurship program aimed at life science researchers in the field of substance use disorders (SUD). This initiative will equip researchers with essential skills to transform their innovative ideas into viable products, focusing on aspects such as market evaluation, customer discovery, and intellectual property. The course will be delivered in a hybrid format to engage US-based SUD researchers effectively, fostering collaboration and advancing the field.

The Evergreen Foundation Grant supports not-for-profit organizations in Western North Carolina that provide essential services for individuals with behavioral health, intellectual, and developmental disabilities. Established in 1977, the Foundation allocates funding through a competitive grant process, typically issuing 25 to 30 grants annually. Eligible applicants include agencies serving these populations and those with 501(c)(3) status. Priorities include infrastructure support, education, and advocacy, ensuring vital services reach the communities in need.