Best Operating Grants for Nonprofits in Ohio

A Little HOPE, Inc. is a charitable foundation that provides grants to organizations offering bereavement support services and grief counseling for children and young adults who have lost a loved one. The grant amounts vary based on project scope and budget. Applications are by invitation only, sent out each October, and interested organizations should submit an email with necessary details for consideration.

The Vernon L. Odom Fund, established in 1993 by the Akron Community Foundation, honors civil rights leader Vernon L. Odom. It supports programs that enhance diversity and improve the quality of life in local minority communities. With nearly $245,000 in grants awarded, the fund addresses specific needs of minority groups in Akron, promoting education and advocacy. As the minority population grows, the fund continues to play a vital role in fostering community empowerment and ensuring Odom's legacy endures.

The William L. and Diane C. Wilson Scholarship for Karst Science, established in 2002, honors the legacy of William L. Wilson and aims to support innovative karst scientists. Funded by Diane C. Wilson, it provides a one-time award of $2,500 and recognition at the KWI spring banquet. Eligible candidates must be enrolled in a master's program focused on karst science and its subfields, while PhD students are excluded. This scholarship fosters the growth of new talent in karst research.

The Alice M. Ditson Fund supports recording projects that aim to document and promote the music of younger, lesser-known American composers. The fund prioritizes living composers of classical concert music, especially those in the early stages of their careers, while also recognizing established composers who deserve greater visibility. Eligible applicants include organizations with a fiscal sponsor or non-profit status, and projects must involve significant contemporary American music.

This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.

The Investigator Initiated Research (IIR) Grants program by the Anesthesia Patient Safety Foundation aims to enhance patient safety in anesthesia care through innovative research. Grants up to $200,000 (or $300,000 with waiver) are available for projects addressing critical safety issues, with a focus on studies leading to measurable improvements in outcomes. The program encourages collaboration and creativity, prioritizing research that lacks alternative funding sources, while also supporting junior investigators with mentorship opportunities.

The BJA FY26 Body-Worn Camera Policy and Implementation Program aims to assist law enforcement agencies in acquiring body-worn cameras and establishing comprehensive BWC programs. This initiative addresses the increasing demand for reliable video evidence in criminal cases, enhancing documentation and prosecutorial outcomes. By utilizing BWCs, agencies can deter assaults on officers and protect them against false accusations, ultimately improving community trust and accountability in law enforcement practices.

The National Multiple Sclerosis Society offers the Sylvia Lawry Physician Fellowships to support MDs in acquiring essential clinical trial training. This fellowship aims to enhance expertise in conducting complex trials for MS therapies, fostering skills in protocol design, patient recruitment, and data analysis. Applicants must have relevant medical training and be engaged in ongoing MS clinical research. The program is vital for addressing the increasing demand for trained professionals in MS clinical trials, contributing to advancements in treatment.

LSC’s Basic Field Grants aim to enhance access to civil legal services for low-income individuals across the U.S. and territories. These grants support eligible organizations for up to three years through a competitive application process. The funding is allocated to specific service areas, which change annually, and focuses on providing comprehensive legal assistance. The program includes three types of service areas, ensuring diverse populations, including agricultural and Native American communities, receive necessary legal support.

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Scholarships

Cherokee Nation Foundation offers a diverse range of scholarships to help reverse the trend of rising student debt. Students may receive up to two CNF scholarships per academic year. All opportunities are reserved for Cherokee Nation citizens, unless otherwise noted in the description.

Bill Rabbit Legacy Art Scholarship

Applicant must be enrolled in an accredited, four-year, higher education institution pursuing a degree in fine arts or art education with a minimum 3.0 GPA. Accepted focuses include drawing, painting, sculpture, pottery, traditional beadwork and textiles. Three pictures of artwork must be included with application for consideration. This is a one-year scholarship reserved for Cherokee Nation and United Keetoowah Band citizens residing within the Cherokee Nation jurisdictional area.

The Anderson Foundation for Autism Grant supports organizations aiming to enhance the quality of life for individuals with autism. Grants of up to $50,000 are available for qualified 501(c)(3) organizations, enabling them to implement impactful programs. The foundation not only funds its own initiatives but also extends support to other entities dedicated to similar goals. This initiative emphasizes a collaborative approach to improving autism care and support.

The Tommy Wells Foundation Grant supports youth aged 4-18 in music and hockey programs by providing financial assistance. As a 501(c)(3) nonprofit, the Foundation raises funds to honor Tommy Wells' legacy. Organizations in the greater Nashville, TN area are preferred for funding. The TWF encourages applicants to request funds for those who will benefit most, ensuring accountability by requiring confirmation of fund usage within a year.

The Bay Area Lyme Foundation's Emerging Leader Award supports innovative research in Lyme disease, offering two $150,000 grants to post-doctoral and early-career scientists. Applicants are encouraged to propose proof-of-concept projects that enhance diagnostics or therapeutics. The award seeks to attract talent and foster scientific leadership in biomedical sciences. Evaluation criteria include the potential for novel therapies, scientific rationale, and support from institutions. This opportunity is ideal for those new to tickborne disease research.

The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22) aims to support postdoctoral fellows from underrepresented backgrounds in transitioning to tenure-track positions. This award provides essential funding for salary and research support for three years, enabling candidates to establish independent biomedical careers. Key deadlines for applications range from February 2025 to October 2027, ensuring ample opportunity for eligible researchers to secure funding for their career development.

The ACS Award for Encouraging Women Into Careers in the Chemical Sciences recognizes individuals who promote women's interests in chemistry, fostering their professional development. The award includes a $5,000 cash prize, a certificate, and a $10,000 grant to an academic institution designated by the recipient. Additionally, up to $1,500 for travel expenses to the award presentation will be reimbursed. This initiative highlights the importance of diversity in the chemical sciences and supports women's career advancement.

The Celiac Disease Foundation offers the Jocelyn Silvester Rising Villus Student Research Award to encourage medical students and residents to pursue celiac disease research. This prestigious award provides a $5,000 stipend for a 10-week mentored research experience across North America, honoring Dr. Jocelyn Silvester's contributions to the field. Recipients must secure a mentor and maintain good standing in their academic programs, ensuring a commitment to advancing celiac disease research.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Lionel and Muzzie Wood Family Scholarship Fund

The Muzzie Wood Scholarship was established in loving memory of Muzzie by her family after she passed away on March 16, 2001. In 2010, the name of the fund changed to the Lionel and Muzzie Wood Family Scholarship Fund and its support of Battle Creek area students expanded. Muzzie enjoyed spending time with her husband, Woody, their three daughters, stepson, and eight grandchildren. She loved the outdoors, flower and vegetable gardening, sewing, remodeling, fishing, and turkey and duck hunting. Her husband laughingly recalls a time she wore her sneakers in the river, knee-deep, and caught a salmon bare handed! Muzzie always had a smile on her face and gave more than she received. Woody, enjoys an active and blessed life rarely missing an opportunity for fun and fellowship at the Y Center of Battle Creek and spending time with family and friends, This scholarship is awarded to graduating seniors within Calhoun County who are members of a Missouri Synod Lutheran Church. If there are no eligible members, members of a Christian-based church may also be considered.

The Our Village Grants by the Jack and Jill of America Foundation aim to support 501(c)(3) non-profit organizations dedicated to uplifting African American families. These grants focus on programs that address educational and economic disparities, particularly those exacerbated by the pandemic. Initiatives may include digital learning resources, tutoring, and support for health and food security. The foundation prioritizes organizations that align with their mission to create lasting positive impacts in under-resourced communities.

The Lucille M. Tiro Scholarship, offered by the Delaware Community Foundation, provides a one-time award of $1,000 to a graduating female senior from the Indian River School District. Applicants must demonstrate high academic achievement and financial need, with preference given to those pursuing degrees in the Arts. This scholarship is part of a broader initiative by DCF, which awarded a record $850,000 to 245 students for the 2024-2025 school year, fostering educational opportunities in Delaware.

The Cloutier-Valenti Legacy Scholarship, funded by the Delaware Community Foundation, offers a one-time award of $1,000 to graduating seniors from selected high schools in Delaware. Eligible students must enroll in an accredited institution, demonstrate financial need, and show involvement in community activities. The scholarship aims to support students pursuing degrees in science, contributing to the foundation's mission of enhancing educational opportunities and equity in the community.

The Eleanor B. and Henry H. Stroud, M.D. Memorial Scholarship, offered by the Delaware Community Foundation, provides a one-time award of $5,000 to Delaware residents pursuing medical degrees. This scholarship emphasizes excellence, ethics, and compassion in medicine, along with financial need and academic promise. Eligible applicants can reapply for up to four annual awards, with special consideration for those demonstrating innovation in medicine. The DCF awarded a record $850,000 in scholarships to 245 students for the 2024-2025 academic year.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Louis E. Maddalena Battle Creek Area Scholarship

The Louis E. Maddalena Battle Creek Area Scholarship Fund has been established for the purpose of providing scholarships to greater Battle Creek area public and private high school graduating seniors and graduates, pursuing post-secondary educational opportunities, who have accepted to or are enrolled at a 2-year or 4-year college or university, technical or trade school. Preference will be given to graduating seniors.

The Joseph James Scholarship, managed by 10,000 Degrees, offers support to students from Bayside Martin Luther King Jr. Academy who graduated between 2013 and 2019. Eligible candidates can receive funding for up to two years, depending on their attendance duration. This scholarship aims to combat educational segregation and provides recipients with access to vital internship opportunities, enhancing their career readiness and skill development in various fields.

The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) grant invites applications for mid-phase clinical trials focusing on natural products such as botanicals and dietary supplements. It aims to advance scientific knowledge by determining optimal dosing and patient responses. Applicants must provide preliminary data demonstrating bioavailability and measurable impacts on target engagement. This initiative will not support efficacy trials for cancer treatments and encourages early contact with NCCIH scientific contacts.

Delaware Art & Design Scholarship

Awards:

• One time award of $20,000. Students may reapply each year.

The NCCIH Natural Product Early Phase Clinical Trial Award supports innovative clinical trials of natural products, such as botanicals and dietary supplements, with a strong scientific basis. Applications are encouraged to explore optimal delivery methods and combinations with other treatments. Funding is available for up to three years to assess the impact on target engagement and clinical outcomes, aiming to translate basic science findings into practical clinical applications.

The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33) invites research proposals for early phase clinical trials of natural products, including botanicals and dietary supplements, emphasizing scientific validity for further testing. Applicants may receive up to three years of funding for pharmacokinetics and bioavailability studies, with potential for an additional three years to evaluate clinical outcomes. This initiative aims to optimize natural product delivery through innovative study designs.