Best Grants for 501(c)(3) in Ohio

Ohio 501(c)(3) organizations serving children, families in need, or advancing medical research can seek grants to support education, health and human services, arts and culture, environmental initiatives, and community programs. With a mission to enhance quality of life, Sam J Frankino Foundation provides more than US $1,000 for impactful projects primarily in Northeast Ohio counties.

Ohio 501(c)(3) organizations working in education, human services, conservation, health, or cultural programs can apply for McGraw Foundation support; typical awards range from US $2,000 - US $10,000. Grants, generally for organizations in the greater Chicago area, may fund general operations, specific projects, or occasional capital needs across these focus areas.

Agricultural and forest producers in Ohio seeking to enhance environmental stewardship on working lands can receive technical and financial assistance to improve soil, water, wildlife habitat, and overall operation resilience. Focused on conservation, USDA Natural Resources Conservation Service of Ohio offers five-year CSP contracts that support existing practices and fund additional conservation activities across entire operations.

Nonprofit organizations serving community needs in Ohio’s Pickaway County can apply for flexible funding to enhance local quality of life across areas like education, health, human services, and community development. Pickaway County Community Foundation provides competitive, donor-supported grants for public charitable purposes, with guidelines, priorities, and funding availability varying from year to year.

Agricultural producers, non-industrial private forest owners, Tribes, and water management entities in Ohio can receive financial and technical assistance to implement conservation practices on working lands. USDA Natural Resources Conservation Service of Ohio’s EQIP program supports projects that improve water and air quality, soil health, wildlife habitat, energy efficiency, and overall sustainable agriculture, which may benefit 501(c)(3) partners in the state.

Graduate students researching drinking water quality, environmental science, or public health can receive US $3,000 to advance projects with practical impact for the water industry. Focused on water-related research, American Water Works Association invites Ohio-based or Ohio-serving scholars to apply for the Dr. Philip C. Singer Scholarship supporting timely, actionable graduate work.

Grassroots resident groups in Cleveland and East Cleveland can receive US $500 - US $5,000 to run neighborhood-based projects in arts and culture, community building, or senior and intergenerational activities. Focused on resident-led initiatives, Suite 1300 Services invites Ohio community groups, including emerging 501(c)(3) efforts, to strengthen local connections and improve quality of life.

Ohio 501(c)(3) nonprofits working on economic and workforce advancement, safe and affordable housing, or community arts and culture may be eligible for this program. Grants from US Bancorp Foundation help organizations in designated U.S. Bank communities, with priority for those led by people of color and addressing multiple “work, home, and play” pillars.

With a mission to support environmental sustainability, American Honda Motor provides Ohio 501(c)(3) nonprofits and schools with US $25,000 - US $100,000 for decarbonization, clean energy, and efficient resource-use programs. Eligible projects must primarily benefit communities near Honda operations, such as energy upgrades, solar or wind installations, recycling, composting, and other conservation initiatives.

Nonprofit charitable organizations in Ohio working on affordable housing, education, workforce readiness, or small business growth can apply for KeyBank Foundation’s grants of US $10,000 - US $25,000. Grants from KeyBank Foundation help 501(c)(3) groups strengthen neighbors, expand educational access, build financial literacy, and improve employment outcomes in communities where KeyBank operates.

Ohio 501(c)(3) organizations serving women and children through humanitarian aid, education, health care, or social services can apply for funding to build self-sufficiency and resilience. The Father's Table Foundation provides up to US $750,000 for programs such as homelessness support, employment readiness, food security, microfinance, child welfare, and anti-human trafficking initiatives.

Undergraduate students in Ohio pursuing environmental science or environmental engineering degrees can receive merit-based scholarships supporting tuition, fees, books, PPE, tools, instruments, and field equipment. Focused on environmental and engineering disciplines, the Ohio Environmental Protection Agency offers up to US $5,000 for juniors and seniors and up to US $2,500 for two-year programs.

Ohio 501(c)(3) charities and eligible educational or religious organizations can access funding and in-kind support for community programs through The Caesars Foundation. Support may benefit initiatives in social equity and education, climate change and food security, or responsible play and mental health, particularly in Franklin County communities served by Caesars properties.

Ohio schools, park districts, conservation groups, local governments, and other organizations with a federal tax ID can receive up to US $7,500 for aquatic education and stewardship programs in Ohio. Focused on aquatic ecosystem education, the Ohio Department of Natural Resources invites 501(c)(3) and similar organizations to propose hands-on learning experiences that are open to all citizens.

Undergraduate-focused higher education institutions in Ohio conducting biomedical research can apply for NIH Academic Research Enhancement Awards to support small-scale projects and student research experiences. The US Dept. of Health & Human Services National Institutes of Health provides up to US $375,000 to institutions that award baccalaureate science degrees and have limited prior NIH funding.

Ohio 501(c)(3) nonprofits focused on economic mobility or affordable housing can access funding and a two-year leadership development program through Bank Of America Charitable Foundation’s Neighborhood Builders Program. Eligible organizations must be financially sound, have a three-year impact plan, be based in an eligible Ohio market, and commit senior and emerging leaders to the training.

Local education agencies and community-based organizations in Ohio can use this grant for high-quality after-school, summer, and expanded learning time programs serving students from economically disadvantaged families in low-performing schools. The Ohio Department of Education and Workforce funds multi-year initiatives focused on academics, youth development, and family engagement, which may include 501(c)(3) nonprofit providers as eligible partners.

Early-career research scientists at academic or research institutions in eligible low- and middle-income countries can apply for the Emerging Global Leader Award to support mentored clinical research and career development. Grants from the National Institutes of Health help Ohio-based 501(c)(3)s partnering with LMIC investigators advance global health projects across areas like cancer, cardiovascular disease, mental health, and environmental health, with awards around Approximately US $140,000.

Ohio 501(c)(3) organizations working in education, environmental conservation, or community health and vitality can seek project support that benefits communities where Cleveland-Cliffs operates. Grants from Cleveland Cliffs Foundation help nonprofits expand STEM education, restore land and water, improve public health, and strengthen underserved neighborhoods in these local areas.

Perrigo Company Charitable Foundation Grant

The Perrigo Foundation is committed to empowering individuals and global communities by supporting programs and organizations that promote health, well-being, and education. We aim to prepare students and young adults for the workforce, providing accessible career pathways that inspire and empower individuals to reach their full potential. The Foundation is proudly funded by Perrigo Company plc.

Mission Statement

To provide financial support to non-profit organizations that promote our commitment to enhancing the health, well-being and education of individuals and families in the communities in which Perrigo operates. 

Vision Statement

To help improve and positively impact communities by improving access to quality health services, creating educational opportunities, and supporting the needs of the under-served.

Giving Back to Our Communities

Healthcare

We are providing program stability and capacity building for key community agencies, supporting local nonprofits to improve the quality and accessibility of services, and increasing the quality of mental health services, especially for children and families. 

Education

 Education, post-secondary scholarships, and support for first-generation and low-income students primarily focused on a STEM career, advancement for STEM curriculum, and resources in the K-12 classrooms. 

Supporting the Underserved

Community engagement and well-being, ensuring access to basic human necessities such as food, housing, end-of-life support, and necessary social services.

Nonprofit and charitable organizations with 501(c)(3) or 170(c)(1) status serving communities in Ohio can seek program-specific support for low- and moderate-income residents. Focused on community revitalization, services, affordable housing, and economic development, Huntington National Bank invites partners—by local invitation—to advance financial empowerment, food security, digital inclusion, workforce development, and related equity-focused initiatives.

The Fogarty Emerging Global Leader Award supports early career research scientists from low- or middle-income countries (LMIC) by providing research funding and mentored career development for three to five years. This program encourages LMIC scientists in health-related fields to develop projects aligned with their country's health priorities, fostering independent research careers within their institutions. Applications are welcomed from junior faculty members, enhancing global health research and capacity in LMICs.

The Ohio AmeriCorps Formula Grants, administered by ServeOhio, engage over 80,000 Americans annually in meaningful service across various sectors. These grants support local nonprofits and community organizations in addressing critical needs in education, health, and the environment. By participating in AmeriCorps, members gain valuable skills and experience while earning educational scholarships, fostering stronger communities through civic engagement and volunteerism.

About CommonSpirit

A calling that defines and unites

At CommonSpirit Health, we passionately care for the most vulnerable, relentlessly innovate how and where healing can happen and believe in uniting to benefit the common good. Our expansive network spans diverse communities, uniquely positioning us to meet their changing needs, improve population health and help chart the path to health equity.

Our mission, vision and values inform every aspect of our work each day and remind us that we serve our patients, their families, our communities – and each other. Our community health, research and home health programs help us address the primary barriers to healthier communities.

Sponsorship requests

We’re proud to support nonprofits that expand access to care, advance health equity and healthier communities. Learn more about our priorities.

Supporting our communities

CommonSpirit Health and our local facilities support nonprofit organizations that share our mission, vision and values. We give priority to programs that improve access to care and promote health equity and healthier communities.

CommonSpirit is proud to support nonprofit organizations that help improve the health and well-being of our communities. Guided by our mission, vision and values, we prioritize projects that focus on advancing health equity, improving access to care and improving community wellness.

The Joyce Foundation's Environment Grants focus on addressing critical environmental challenges in the Great Lakes region, such as climate change and water safety. The foundation prioritizes equitable, carbon-free energy solutions and clean water access for all communities. Grants are awarded to organizations committed to environmental justice and innovation in climate policy, particularly in Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin, ensuring that the voices of affected communities guide project development.

The John Ben Snow Memorial Trust Grant supports educational programs and initiatives that assist individuals demonstrating financial need. Founded in 1975, it prioritizes funding for organizations that enhance educational opportunities, arts, culture, and community initiatives, particularly for youth and disadvantaged populations. The Trust encourages proposals from 501(c)(3) organizations, with grants typically ranging from $10,000 to $20,000. It also considers limited proposals in disabilities, environmental protection, and historic preservation, focusing on educational impact.

The SHF Responsive Grant Program, offered by Sisters Health Foundation, supports projects aimed at enhancing healthy eating, active living, thriving neighborhoods, and mental health in the Mid-Ohio Valley. Eligible applicants include 501(c)(3) nonprofits and public institutions targeting specific counties in West Virginia and Ohio. The program prioritizes evidence-based strategies to promote health and well-being, foster community resources, and improve access to essential services, making it a vital resource for local organizations seeking funding.