Best Operating Grants for Nonprofits in Ohio

The DoW Ovarian Cancer Academy Early-Career Investigator Award supports junior faculty in conducting innovative ovarian cancer research. Established in FY09, this unique virtual academy fosters mentorship, collaboration, and networking among Early-Career Investigators (ECIs) and their mentors. Participants engage in monthly webinars and annual workshops, enhancing their research skills while contributing to impactful studies in ovarian cancer. The program aims to cultivate a new generation of highly productive researchers in this critical field.

The William C. Risser Charitable Trust Grants support mental health research, particularly in Schizophrenia. This private foundation assists 501(c)(3) nonprofit organizations across the U.S. with grants typically ranging from $25,000 to $55,000. Administered by Wells Fargo, the Trust awards 1-2 grants annually, focusing on program support for scientific and educational research. Eligible organizations must meet IRS exemption requirements.

The WAEF Scholarships, supported by the Washington Apple Education Foundation, offer over $1 million in educational awards to more than 300 students this year. These scholarships are primarily for individuals with ties to the tree fruit industry in Washington, with a special focus on the Danna Gebbers Guzman Memorial Scholarship, aimed at nursing students. Eligible recipients can use the funds at accredited institutions with nursing programs.

The Zachary Adam Giordan-Lascari Memorial Scholarship, offered by the Community Foundation of Southern New Mexico, supports fathers pursuing physical therapy education at accredited institutes. This scholarship aims to assist students from diverse backgrounds, including those with disabilities and members of the LGBTQIA+ community. With a focus on community impact, this fund exemplifies the Foundation's commitment to enhancing educational opportunities and fostering a thriving future for recipients in Southern New Mexico.

The NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) is designed to support clinical trial planning and implementation for dental, oral, and craniofacial conditions. This funding opportunity encourages applications that propose innovative research strategies within the NIDCR mission. Key deadlines span from February 2025 to January 2028, with emphasis on milestone-driven planning phases leading into possible clinical trial phases.

The Igor Gorin Memorial Award, established in 1993 by the Community Foundation for Southern Arizona, honors the legacy of Igor Gorin by supporting aspiring vocalists. With $382,000 awarded to 49 young talents, this fund provides unrestricted financial assistance for coaching, travel, and auditions. The 2026 award offers up to $12,000, aimed at those overcoming financial barriers to pursue operatic careers, ensuring that exceptional vocalists can thrive in their artistic journeys.

The Cystic Fibrosis Foundation's Student Traineeship Award supports students in engaging with cystic fibrosis research through hands-on projects. With a maximum funding of $4,000 for one year, the program aims to inspire students to pursue careers in CF research or care. Eligible applicants must be enrolled in a degree program and collaborate with a faculty mentor on a relevant project. This initiative also emphasizes the importance of maintaining interest in CF-related research among new generations.

The Cystic Fibrosis Foundation offers a Travel Award Supplement aimed at supporting Ph.D. students, postdoctoral fellows, and junior faculty. This funding of up to $3,000 enables trainees to participate in off-site workshops or training programs to enhance their research skills. Eligible applicants must be active researchers in CF projects, with a minimum of one year of experience. The program excludes conference attendance and for-profit entities, ensuring focused support for advancing cystic fibrosis research.

The Harry Shwachman Clinical Investigator Award, offered by the Cystic Fibrosis Foundation, supports clinically trained physicians transitioning to independent researchers in cystic fibrosis. It provides up to $133,000 per year for three years to facilitate research tailored to individual interests. The funding covers personnel costs and supplies, promoting a strong mentorship during this critical stage of their academic careers.

The Path to a Cure (PTAC) - Postdoc-to-Faculty Transition Award by the Cystic Fibrosis Foundation supports postdoctoral fellows in advancing their research careers in cystic fibrosis. This program offers up to five years of funding, including 3 years for research training and 2 years for transitioning to an independent faculty position, with a maximum support of $110,000 per year. It aims to foster innovative research that develops new therapies for cystic fibrosis.

Community Collaboration Challenge

Applications for the 2026 Community Collaboration Challenge are now open! With support from the Leon Lowenstein Foundation, the Challenge provides $5,000 – $10,000 awards to communities and is designed to support collaboration that expands and pilots evidence-based K-12 student supports in the form of high-impact tutoring, mentoring, student success coaching, postsecondary transition coaching, and/or wraparound/integrated student supports.

The Cystic Fibrosis Foundation offers the Path to a Cure (PTAC) Postdoctoral Research Fellowship Award to support innovative research training in cystic fibrosis (CF). Aimed at enhancing scientific knowledge and facilitating the transition to independent careers, this program funds projects targeting the development of new therapies for CFTR variants. Awards can reach up to $75,000 in the first year and $76,000 in the second year, fostering foundational research that could lead to breakthroughs in CF treatment.

The DoW Military Burn, Patient-Centered Research Award aims to enhance the implementation of burn care research into clinical practice for military settings. The FY26 program supports clinical trials and research that directly benefit burn patients in resource-limited environments, fostering collaborations between experienced researchers and junior scholars. This initiative addresses critical gaps in combat burn care, ensuring effective interventions and guidelines are developed and utilized in operational battlespaces.

The FY26 Military Burn Research Program (MBRP) Discovery Award aims to support groundbreaking research in combat-relevant burn care. This award encourages innovative and exploratory studies that provide new insights and foundational data for future clinical research. The focus is on novel approaches that lay the groundwork for scientific advancements and product development in burn care, ensuring robust preliminary data generation for subsequent research initiatives.

The Pizza Hut Foundation is offering scholarships for students demonstrating financial need and community leadership. Eligible applicants must be U.S. residents aged 17-26, enrolled in accredited post-secondary education for Spring 2026, and maintain a minimum GPA of 2.5. Scholarship amounts range from $500 to $5,000, with distribution to be made in Spring 2026. The application period runs from July 8 to September 5, 2025, with notifications for recipients by November 17, 2025.

The FY26 Military Burn Research Program (MBRP) Technology/Therapeutic Development Award (TTDA) aims to translate promising preclinical findings into burn products for clinical use in challenging environments. This award supports the development of both tangible products, like medical devices, and knowledge products that enhance health outcomes. A new Mentorship Option encourages collaboration between experienced researchers and junior scientists, fostering the next generation of leaders in military burn care research.

This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.

Kickstart Your Project with a Mini-Grant

At H2O for Life, we never want finances to be a barrier to participating in a service project. The H2O for Life Mini-Grants are meant to be a supportive resource for teachers and students who want to kick-start their projects with us. Mini-grants of up to $500 will be awarded to support teachers and students with the necessary funds for their service-learning programs.

Our Mission

H2O for Life offers a service-learning opportunity designed to engage, educate and inspire youth to take action to solve the global water crisis by raising awareness and funds to support implementation of water, sanitation and hygiene education projects for global partner schools.

Since 2007, nearly 1 million students from H2O for Life schools have supported water, sanitation, and hygiene education projects for partner schools in the developing world.

What is H2O for Life doing to address the global water crisis?

H2O for Life’s service-learning opportunities are designed to engage, educate, and inspire youth to become global citizens. Our innovative school-to-school approach helps young people develop a concern for others by taking a major global crisis and scaling it down to a manageable size — one water project in the developing world.

Through the service-learning opportunity we provide, students learn that they can make a tangible difference for the students in their partner school.

About All Points North Foundation

All Points North Foundation is dedicated to navigating communities upward.

All Points North Foundation was founded in 2011 by a family who believes passionately that everyone has a “true North” – a place of achievement – and that everyone should have equal opportunity and access to realize their goals.

Our Vision

We envision a nation where the middle school years are seen as an important, vital time in the lives of youth, and where the public middle school education experience in underserved communities measurably improves

We also envision a nation where the integration of solar benefits families, local economies and the environment.

Our Priorities

All Points North Foundation funds grantees in two areas – public middle school education (grades 6-8) and solar – that have the power to help communities nationwide navigate upward.

Grant Making

All Points North Foundation seeks collaborative partnerships with grantees in our two priority areas.

Education

All Points North Foundation is one of the few foundations focused on public middle school education, defined as grades six through eight. We recognize the vital importance of the middle school years in shaping the future of our nation’s youth.

All Points North Foundation seeks to measurably improve public middle school education in underserved communities, whether urban or rural, through two priorities:

• Funding programs that prepare and retain middle school teachers in an ever-changing education climate.
• Helping students grow both academically and socially/emotionally.

Middle schoolers need a nurturing school environment and expertly trained, passionate teachers who can help foster academic, social and emotional growth.

It’s critical for teachers to be adequately prepared for rapidly changing classrooms and school environments, and to be continuously encouraged and inspired to serve as key role models for middle school students.

It’s also critical for middle school students to be inspired and engaged, and excited to embrace the path of learning ahead. Research clearly indicates the habits and patterns set in middle school forecast success for students in their high school years and beyond.

The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.

The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.

The Kelly A. McAdams Scholarship, offered by the San Luis Obispo County Community Foundation, supports high school seniors, undergraduates, and returning students in their educational pursuits. Established in memory of Kelly A. McAdams, this scholarship aims to empower local students to achieve their academic and career goals. With a commitment to fostering diversity and inclusivity, the foundation encourages applicants from all backgrounds to apply for this opportunity in the 2025-2026 academic year.

The Lois and Duke Williams Memorial Scholarship, offered by the San Luis Obispo County Community Foundation, aims to support students who have faced challenges in their lives and wish to pursue post-secondary education. Open to high school seniors, undergraduates, and returning students, this scholarship represents a commitment to fostering educational opportunities for those who strive for success despite obstacles. Apply now to take your first step towards achieving your dreams!

The Manford and Maude Brown Medical Education Scholarship, offered by the San Luis Obispo County Community Foundation, supports local residents pursuing degrees in medical or healthcare fields. Open to high school seniors, undergraduates, and returning students, this scholarship aims to empower aspiring healthcare professionals in achieving their educational goals. With a commitment to inclusivity and community support, it fosters a brighter future for students in San Luis Obispo County.

The Maureen 'Mo' Clancy Memorial Scholarship supports female students from San Luis Obispo County who have participated in cross country or track and field during high school and are pursuing post-secondary education. This scholarship aims to empower young women, fostering their educational and career aspirations while promoting diversity and inclusion within the community. Applications for the 2025-2026 academic year are welcomed from high school seniors, undergraduates, and returning students.

The Richard J. Weyhrich Leadership Scholarship, offered by the San Luis Obispo County Community Foundation, aims to support high school seniors, undergraduates, and returning students with demonstrated leadership potential. This scholarship, established in memory of Richard Weyhrich, a West Point graduate and U.S. Army officer, provides financial assistance to help students achieve their educational and career aspirations. The foundation fosters an inclusive environment, encouraging all students to apply and reach their full potential.

The Richard K. Sauret Viticulture and Enology Scholarship, offered by the San Luis Obispo County Community Foundation, supports students pursuing degrees in viticulture or enology at a four-year college. This scholarship aims to empower high school seniors, undergraduates, and returning students in San Luis Obispo County. By providing financial assistance, it encourages academic and career advancement, fostering the next generation of leaders in the viticulture and enology fields.