Best Operating Grants for Nonprofits in Ohio

The WCCF: Employment Resource Fund Grant aims to enhance workforce development in Wayne County by providing financial support to local non-profits that offer employment programs. Established in 1987, this fund assists individuals in gaining the skills necessary for better job opportunities. It is open to tax-exempt non-profits and government entities that directly benefit the community. The foundation prioritizes initiatives that empower adults to secure sustainable employment.

The Care Camps Grant supports children with cancer by funding medically supervised oncology camps that provide joy, hope, and healing through outdoor experiences. With the mission to foster a sense of community and shared healing, Care Camps Foundation aims to serve every child and family affected by pediatric cancer in the US and Canada. By collaborating with donors and volunteers, the foundation ensures that each contribution maximizes benefits for the families in need.

The Bee Foundation For Brain Aneurysm Prevention (TBF) invites proposals that further the mission of reducing the number of deaths caused by brain aneurysms. Proposals directed at understanding the early detection, pathophysiology, genetic predisposition, or treatment will take priority. Proposals from a variety of disciplines (including but not limited to translational Neurosciences, Neurosurgery, Neurology, Radiology, Genetics) are encouraged and multidisciplinary proposals that illustrate a multi-faceted approach will be weighted highly.The purpose of this program is to promote novel approaches to the early detection and prevention of ruptured cerebral aneurysms, or early emergency and critical care treatment (excluding device therapies). We invite proposals that test an innovative hypothesis or develop new outcomes via interdisciplinary or translational research. Applications with more than one investigator must indicate how the different expertise of the co-investigators will contribute to the overall goals of the project.  Grant Funding:

• $20-25,000 total amount to be distributed, but not limited to only 1 awarded applicant
• Applicants may request up to $25,000

The Patient-Centered Outcomes Research Institute (PCORI) will announce funding for patient-centered comparative clinical effectiveness research (CER) studies focusing on rare diseases. This initiative encourages collaboration and aims to fill critical research gaps affecting approximately 30 million Americans with rare diseases. Applications can request up to $12 million over five years, including coverage for patient care costs. This funding opportunity is set to open on August 12, 2025, with a focus on addressing pressing patient-centered CER questions.

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Women in Leadership of Central Illinois Scholarship Fund

The Women in Leadership of Central Illinois Scholarship Fund was established by the Women in Leadership of Central Illinois to provide scholarship support for women in the Tri-County (Peoria) area, who are pursuing secondary or post-graduate education or certification at an accredited college or university.

Women in Leadership Mission

To promote leadership among women by providing mentoring, networking, and educational opportunities.

The Columbus Foundation

In 1943, during the darkness of World War II, a group of passionate citizens, led by Columbus businessman Harrison M. Sayre, envisioned a way to improve the well-being of the community and the quality of life in central Ohio. With little more than this sound idea and faith, The Columbus Foundation was established.

Our Mission

To assist donors and others in strengthening and improving our community for the benefit of all its residents.

Craig Memorial Scholarship Fund

This scholarship fund was established by the family of John E. Craig, Jr. and Larry William Craig. Both John and Larry were extremely gifted musicians. John was a noted musician in the central Ohio community, studying at the Berklee College of Music in Boston at the time of his death. A well-known musician and businessman, Larry excelled at playing the piano and worked with his father in Craig & Sons Wrecking Company. This scholarship fund will provide support to students who are pursuing careers in musical arts, theatre or drama.

The Marian and Wayne Sinsel Scholarship, established by Marian Sinsel to honor her late husband Wayne, provides financial support to hearing impaired residents of Appalachian Ohio or Fairfield County. This scholarship aims to assist candidates who are 22 years or younger and plan to pursue education at a post-secondary institution in the U.S. with a minimum award of $1,000, ensuring it does not displace existing state or federal funding.

The NIDCD Early Career Research (ECR) Award (R21) provides support for emerging researchers focused on hearing, balance, smell, taste, voice, speech, or language. This award is designed to help scientists establish their independent research careers and is not intended for thesis or dissertation work. The funding can be utilized for various projects, including secondary data analysis and the development of new research methodologies, facilitating the transition to larger R01 applications.

The Jane Tschappat Nursing Advancement Scholarship, established by The Columbus Foundation, aims to support nurses pursuing advanced education in Ohio. Initiated in 1943, it honors Jane Tschappat, a dedicated nurse and public health leader. Eligible candidates must be enrolled in accredited programs, hold a valid RN license, and demonstrate financial need. The scholarship offers a minimum award of $1,000, empowering nurses to navigate the evolving healthcare landscape and enhance their professional qualifications.

The Hearst Foundation: Education Grant aims to support outstanding nonprofits that promote education across various levels, focusing primarily on higher education. With a minimum grant size of $100,000, the foundation prioritizes organizations demonstrating significant impact and sustainability. They support innovative educational models, professional development, and scholarships, specifically targeting underserved populations. Since the 1940s, the foundation has evolved while maintaining its commitment to fostering healthy and productive lives for all individuals in the United States.

The Career Guidance for Trainees Grant, offered by the Burroughs Wellcome Fund, aims to enhance the career development of early career administrators focused on PhD scientists. This grant supports a workshop that equips participants with research evaluation skills to create impactful career-focused interventions. Participants will receive a $15,000 grant to implement their projects, develop networks, and share findings at national meetings, fostering a diverse scientific workforce essential for research innovation and public service.

The Brett Candela Lacrosse Scholarship, established by the family of Brett Candela, honors his passion for lacrosse and supports central Ohio players pursuing higher education. A standout athlete from Columbus, Brett was recognized for his leadership and competitiveness in lacrosse and basketball. This scholarship aims to invest in student-athletes who embody his values of dedication, teamwork, and perseverance, ensuring that the next generation of lacrosse players can achieve their educational goals while upholding Brett's legacy.

About Pfizer

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement, or education) to improve patient outcomes in areas of unmet medical need that are aligned with medical and/or scientific strategies.

About the American Headache Society

The American Headache Society strives to improve the lives of people impacted by migraine and other headache disorders. The AHS is a professional society of health care providers dedicated to the study and treatment of headache and face pain. The Society’s objective is to promote the exchange of information and ideas concerning the causes and treatments of headache and related painful disorders. Educating physicians, health professionals, and the public while encouraging scientific research are the primary functions of the Society.

Quality Improvement and/or Research Grants: Migraine and Women’s Health

Migraine is a prevalent and debilitating neurological disease that disproportionately affects women, impacting quality of life, productivity, and overall health. Recognizing the need for innovative solutions and enhanced care, Pfizer and the American Headache Society (AHS) are collaborating to offer a new grant opportunity inviting proposals for collaborative quality improvement and research projects focused on migraine and women's health. This Request for Proposals (RFP) aims to foster high-impact research and initiatives that advance scientific understanding, improve patient outcomes, and address gaps in care. Projects should also contribute to the core goal of the AHS – improving the lives of people impacted by migraine and other headache disorders.

Objectives

• To advance research in migraine and women's health through collaborative pre-clinical and clinical projects
• To promote quality improvement initiatives that enhance diagnosis, treatment, and management of migraine in women
• To encourage multidisciplinary approaches that integrate clinical expertise, patient-centered care, and innovative research methodologies
• To generate measurable and actionable outcomes that contribute to improved standards of care and inform future research directions for women with migraine

31Heroes

On August 6, 2011, a tragedy shook the military community and Americans everywhere. In a single instance, America lost 30 military service members, many of whom were members of the Navy SEAL community—and one military K9– when a CH-47 Chinook helicopter, call sign Extortion 17, was downed in Afghanistan.

Established to honor the 31 Americans killed in action on August 6, 2011, 31Heroes serves to impact the lives of our nation’s heroes and their families, while remembering the fallen, through athletic endeavors and competitive fundraising events.

Our Mission: The mission of 31Heroes is to raise money and awareness through social and athletic events to support the families of Extortion 17 and honor their legacy by funding treatment for Veterans suffering from mental health issues.

Our Focus

Our goal is to create opportunities for the families of Extortion 17 to create healthier lifestyles and to provide financial relief in times of need. We consider it our responsibility to make a positive impact in the lives of each family. Whether through grants we provide, or through partnering with other non-profit organizations that offer programs or services that we do not, we are devoted to the families and creating a legacy the men of Extortion 17 would be proud of.

Guidelines

• Individual limits will not exceed $3750 annually
• Family Grants range from $750 to the maximum range of $1500
• Family members must submit an online application for consideration
• Applications may be submitted at any time during this funding cycle
• Priority and funding will be based on the Primary Next of Kin list

Lifestyle Grants

Lifestyle Grants are aimed at improving health and lifestyle via physical fitness, nutrition, holistic treatment, etc. Limit for this grant is $1500

Batten Disease Support, Research, and Advocacy (BDSRA) Foundation

BDSRA is dedicated to funding research for treatments and cures, providing family support services, advancing education, raising awareness, and advocating for legislative action. Founded in 1987, by parents seeking to build a network for those diagnosed with Batten disease, BDSRA is now the largest support and research organization dedicated to Batten disease in North America. BDSRA believes that to effectively unravel the mysteries of Batten disease, the worlds of medical science, research, and families must work together toward a common goal: discover treatments and cures while assuring a better quality of life for those living with the disease.

Batten Family Help Grant

The BDSRA Foundation is committed to supporting families of all CLN types in all aspects of their fight against Batten, including the financial challenges they face. BDSRA understands that families in our community caring for people with Batten disease are often faced with financial challenges that further interfere with their well-being.

We offer grants to help cover the costs associated with battling Batten disease, such as emergency travel, loss of employment, hospital bills, and other challenges our families might face.

The GEMSSTAR for Emergency Medicine Supplemental Funding Program provides up to $25,000 over two years to support emergency medicine physicians who have received the NIA GEMSSTAR grant. This program aims to enhance the Professional Development Plan of GEMSSTAR awardees, ensuring they receive the necessary funding for their research endeavors. Eligibility is limited to those who have completed their clinical specialty training and are based at U.S. institutions, with funding contingent upon available resources.

The Native American Research Centers for Health (NARCH) program supports federally-recognized American Indian and Alaska Native Tribes and organizations in advancing health-related research. It aims to enhance research careers and infrastructure through a competitive application process. Funded by the US Dept. of Health & Human Services, this initiative invites eligible entities to apply, ensuring that only high-quality proposals undergo peer review for potential funding.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a Notice of Funding Opportunity (NOFO) under the NIH HEAL initiative to enhance research on joint health and pain. This initiative aims to refine the understanding of joint tissues and pain mechanisms, expand clinical phenotyping, and support preclinical testing of novel therapies. Collaborations among experts in neurobiology, pain science, and rheumatic diseases are encouraged to foster innovative solutions for joint pain management.

The AACR June L. Biedler Prize for Cancer Journalism

Prize Summary

The AACR June L. Biedler Prize for Cancer Journalism was established by the AACR in 2015 to raise awareness of the critical role that the media play in educating the public about cancer and cancer research.

Funded by a major bequest to the AACR from cancer research pioneer Dr. June L. Biedler, a scientist, mentor, and former member of the AACR Board of Directors, this prize showcases outstanding examples of cancer journalism and recognizes individual professional journalists who have produced accurate, informative, and compelling stories that enhance the public’s understanding of cancer, cancer research, cancer advocacy, or cancer policy.

The prize provides an unrestricted cash award of $5,000 and a commemorative award.

Categories

Each submission may be considered for only one category, as selected by the candidate on the application form.

Applicants may submit in any of the following categories:

Prize Acceptance

Awardees will be able to accept the prize during the AACR Annual Meeting 2027 in Orlando, April 2-7, 2027.

Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations. 

Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.

Leonard G. McLeod Theatre Scholarship

Receiving a diploma from any high school in Cumberland County.

The JADE Learning Electrical Technologies Scholarship supports students enrolled in North Carolina technical or occupational schools focused on electrical systems technologies. Eligible candidates include undergraduates, graduates, and apprentices who demonstrate financial need and strong academic performance. The scholarship application requires careful attention to specific donor-defined eligibility criteria. Applications open on December 16, 2025, and close on March 3, 2026, with preference given to those pursuing a two-year associate’s degree.

The Multiple Sclerosis Clinical Care Physician Fellowship: Pediatric Care, offered by the National Multiple Sclerosis Society, aims to enhance the training of physicians in providing specialized care for pediatric patients with MS. This one-year post-residency program emphasizes direct patient care and multidisciplinary collaboration. Participants will learn under the supervision of MS specialists, gaining essential skills to improve clinical practices and contribute to the MS community, ultimately leading to better outcomes for those affected by this condition.

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Lawrence & Phyllis DeWolfe Scholarship

Established by the family and friends of Mr. and Mrs. Lawrence DeWolfe to provide college scholarships to graduating seniors from Blue Ridge, Lackawanna Trail, and Mountain View school districts who will major in agriculture, education, a STEM field or law enforcement.

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Cody Albert Memorial Scholarship

Established by Dale and Linda Albert in memory of their son Cody to provide a college scholarship to students from Susquehanna County who will major in the Visual Arts, Psychology, or Physical Therapy and who have overcome anxiety, depression, or other adversity.

The Sidney R. Baer, Jr. Foundation offers Clinical Research Grants to support advancements in the treatment and understanding of schizophrenia and bipolar disorder. Focused on organizations with IRS tax-exempt status, these grants aim to enhance mental health services and research. By funding initiatives in cognitive and behavioral sciences, the foundation seeks to improve the lives of those affected by serious mental illness, ensuring they receive the support and resources necessary for a better quality of life.

Society of Hospital Medicine (SHM)

The Society of Hospital Medicine (SHM) is dedicated to promoting high-value care and achieving optimal outcomes for acutely ill patients. As part of this mission, SHM seeks to address inequities in acute patient care and contribute to a greater dialogue on this important issue. As the home for hospitalists, SHM activates and engages our community to

• Advocate for our specialty, our members, and the diverse patients we serve.
• Promote high-value care and optimal outcomes for acutely ill patients.
• Meet the evolving educational needs of a dynamic specialty.
• Cultivate an inclusive community for hospitalists and support career growth and wellbeing.
• Advance the research and innovation of healthcare delivery, quality, safety, and experience across the care continuum.

SHM’s Excellence in Teamwork Award

This award is presented in recognition of exemplary quality improvement initiatives in hospital medicine that engage the full patient care team. The award is intended to highlight outstanding team approaches to implementing interventions that improve patient care and safety but is particularly interested in projects related to the core competencies in hospital medicine and SHM’s quality improvement resource rooms. 

Recipients of the Excellence in Teamwork in Quality Improvement Award receive recognition at SHM Converge 2026 and complimentary registration for up to 4 team members.

The Cooperative Development Fund Grant supports cooperative development, research, and technical assistance for cooperatives focused on seniors, international development, and affordable housing. Grants, typically ranging from $20,000 to $30,000, are awarded once a year, with a two-stage application process: a concept paper followed by a full proposal for selected applicants. Up to two grants are awarded annually, with decisions announced shortly after the Advisory Board meeting in January.