Best Orange County Grants for Nonprofits in Indiana

Family and Social Services Administration of Indiana

We are steadfast in our mission to break the cycle of poverty by providing Hoosiers with the healthcare, social services, and support necessary to achieve lasting economic independence. Through thoughtfully designed and fiscally sustainable programs, we equip individuals and families with the resources and opportunities they need to build stability, reclaim dignity, and secure long-term success.

School Age Child Care Grant

The Office of Early Childhood and Out of School Learning will support licensed/regulated school-age child care programs in public school corporations, as authorized by IC 12-17-12, or a child care program that is also a not-for-profit organization, exempt from federal income taxation under Section 501(c) (3) of the Internal Revenue Code. Applicants may request a maximum of $40,000 per county. As outlined in IC 12-17-12-16, awarded Grants cannot exceed 90% of the Grantee’s total annual program operating costs. This is a cost reimbursement grant; thus, no funds will be disbursed in advance.

Programs must have been open and operating their school-age child care program for at least one (1) full year preceding the date of application for the School Age Child Care grant and remain in good standing through the entire grant period, and serve children between the ages of five (5) and fifteen (15) years which includes:

• Before and/or after school care offered during the regular school year or during the summer, if summer school is offered.
• Care provided during periods when school is not in session, excluding summer break
• Before and/or after school care for children who attend kindergarten (enrolled in either a full-day or half-day program).

Our Mission: To advance opportunity, affordability, and stability in housing

Individual Development Account (IDA) Program

The Individual Development Account (IDA) Program is an asset development program that assists low-moderate income individuals and families in breaking trends of generational poverty, improving their quality of life, and attaining self-sufficiency through matched savings incentive, education, and building personal financial skills. IDA was established in 1997 through Indiana State legislation (I.C. 4-4-28) and is currently fully State-funded. IDA is administered locally by non-profit community-based organizations with oversight by IHCDA.

Program Summary

Individual Development Accounts are matched savings accounts designed to encourage lowincome families to save for the purchase of an asset. Participants in the program are required to successfully complete financial education as well as training related to a specific asset purchase.

The program round comprises four program years. The round should be broken down as follows: three years for a participant to save, and one year for the IDA Administrator to work on some combination of the following: enrollment, asset purchase, account close-out and reporting.

The objective of the IDA Program is to assist people with limited means in achieving financial independence and becoming financially self-sufficient by providing them the skills to:

• Develop a budget and set goals
• Establish regular saving habits
• Invest in assets

Community Services Block Grant (CSBG)

The Community Services Block Grant (CSBG) is a federally funded investment that provides funds to States, territories, tribes, and local agencies to support services and activities that reduce poverty and empower low-income families and individuals to achieve self-sufficiency. To help Hoosiers in need, IHCDA is mandated to disseminate CSBG funding to selected community action agencies statewide. Nationally, more than 1000 local community action agencies fight poverty and build self-sufficiency for strong families and communities. 

The Community Services Block Grant Act (CSBG) (49 U.S.C. 9901 et seq.) is a noncompetitive federally funded block grant offered through the U.S. Department of Health and Human Services (HHS). The program is meant to support the national network of Community Action Agencies (CAAs) and their work to alleviate the causes and conditions of poverty.

The federal Community Action Program was founded in 1964 by the Economic Opportunity Act (EOA), as part of President Lyndon B. Johnson’s War on Poverty. Originally, federal Community Action Program funds flowed directly to local public and private CAAs. In 1981, Congress repealed the federal Community Action Program and replaced it with CSBG, a state-administered block grant.

Community action's mission is to address the issues of poverty and to increase the self-sufficiency of low-income families. They offer a broad range of anti-poverty programs and work collaboratively with other agencies to build a network of support for Indiana’s most vulnerable populations. CSBG programs include:

• Housing and related services.
• Reduction of Poverty.
• Revitalization of low-income communities.
• Empowering low-income families and individuals in rural and urban areas to become self-sufficient.

Emergency Solutions Grant (ESG)

The Emergency Solutions Grant (ESG) provides funding for essential services, operations, and homeless prevention activities to emergency homeless shelters, transitional housing for the homeless, and day/night homeless shelters. These programs provide basic needs of shelter, food, clothing, and other necessities, and many also provide case management, referrals, rental assistance, and other services to individuals and/or families who are in need of assistance.

The Housing Opportunities for Persons with AIDS (HOPWA) program, administered by the Indiana Housing and Community Development Authority (IHCDA), provides crucial housing funding to non-profit organizations assisting individuals and families affected by AIDS/HIV. Available in 77 counties across Indiana, it prioritizes agencies dedicated to supporting these vulnerable populations, ensuring they receive the necessary resources and support to thrive in their communities.

About Us

Indiana State Parks traces its history back to 1916. Colonel Richard Lieber, an Indianapolis businessman and German immigrant, recommended that a state park system be created as part of Indiana’s celebration of its centennial. Lieber became a national leader in the state parks movement and assisted other states in forming their own systems as well. He became the first Director of the Indiana Department of Conservation, serving for more than a decade.

Indiana Trails Program

The Indiana Trails Program (ITP) is a grant program to support the development of trails throughout the state. The program uses state funds to help connect Hoosiers to outdoor recreation opportunities and natural environments without needing to rely on the use of a vehicle.

How much grant funding is available to applicants?

• The Indiana Trails Program will provide a maximum of 80% reimbursement for eligible projects, up to the maximum grant award amount. The applicant must have at least 20% of the total project cost available at the point of application.
• The grant request minimum is $100,000, and the maximum is $400,000.

About Us

The Indiana Arts Commission (IAC) is an agency of state government, and its funding comes from the Indiana General Assembly and the National Endowment for the Arts (NEA).

A core component to the Indiana Arts Commission’s commitment to investing in the state’s vibrant and rich arts and culture sector are grants, which support people and communities through arts organizations and arts projects.

America250 Grant Program

About the Program

In anticipation of the 250th anniversary of the signing of the Declaration of Independence, the Indiana Arts Commission accepted applications for arts projects, in any discipline, that celebrate American history and connect participants to that history.

The America250 Grant Program is a one-time program made possible through funding from the National Endowment for the Arts and the Indiana General Assembly.

Applicants could request up to $5,000. No matching funds are required.

Applicants recommended for funding will receive the full amount requested and are eligible to be paid in full at the beginning of the grant period provided they are in good standing and supply required information in a timely manner.

Lilly Foundation

To extend Lilly’s charitable reach and impact, the Eli Lilly and Company Foundation (Lilly Foundation) was established in 1968 and is supported by donations from Eli Lilly and Company.

The Foundation is a tax-exempt, private foundation supporting programs that align with its philanthropic priorities.

Grantmaking Approach

The Lilly Foundation’s work is guided by a charitable vision of a world where every person has an opportunity to live their healthiest life. Through grantmaking focused on Lilly Foundation’s charitable vision, grants can serve as a catalyst for closing gaps and empowering individuals and communities to thrive.

All proposals should demonstrate clear alignment with at least one focus area and include charitable outcomes that are measurable and consistent with the Foundation’s long-term charitable goals.

Global Health, K-12 STEM Education and Economic Mobility Grant

Focus Areas

Global Health

Lilly Foundation, through its charitable grants, aims to support permissible charitable efforts to improve access to quality healthcare for resource-limited communities in low- and lower-middleincome countries (L/LMICs) and in the United States. Strengthening access to care is essential for enhancing community well-being and supporting economic stability in resource-limited settings.

The Global Health focus area aims to close gaps in quality healthcare by supporting charitable solutions that improve access, bring care closer to where people live, and address the high burden of non-communicable diseases (NCDs) in resource-limited settings. To the extent permissible, the Foundation prioritizes charitable efforts related to cardiometabolic health in resource-limited settings.

K-12 STEM Education

The K-12 STEM Education focus area aims to close the gaps for students from low-income communities by supporting programs that foster new pathways and pipelines to STEM education through focused K-12 efforts, concentrating on the critical middle school years. The Foundation’s K-12 STEM Education grants are focused on initiatives that benefit Marion County, Indiana.

Economic Mobility

The Economic Mobility focus area supports charitable and educational programs that strengthen workforce readiness, postsecondary and skills-based educational pathways, and housing stability to promote long-term prosperity. This support is focused on Marion County, Indiana, with the goal of improving economic opportunity for low-income communities and advancing community well-being.

The Services * Training * Officers * Prosecutors* (STOP) Violence Against Women Formula Grant Program (STOP Formula Grant Program) supports local communities, including Indian tribal governments and Alaska Native villages, in their efforts to develop and strengthen effective responses to victims of domestic violence, dating violence, sexual assault (including adult survivors of child sexual abuse), and stalking. This also includes victims of domestic violence, dating violence, sexual assault, or stalking who are also victims of trafficking and female genital mutilation or cutting, or forced marriage.

This program is authorized by the Violence Against Women Act (VAWA) and is administered through the Office on Violence Against Women (OVW) and authorized by 34 U.S.C § 10441 et seq.

Funded by the U.S Department of Health and Human Services, the Social Services Block Grant (SSBG) program works to assist residential domestic violence programs in providing emergency shelter to survivors of domestic violence and their dependents. The goal of the program is to help offset the cost of certain operational expenses to include housing, food and other basic necessities in order to give domestic violence shelters more flexibility and the potential to expand services in other areas, based on their needs.

ICJI awards SSBG dollars to supplement federal Family Violence and Prevention Services Act (FVPSA) grants and state Domestic Violence Prevention and Treatment (DVPT) grants, supporting comprehensive initiatives that address the needs of domestic violence victims in Indiana. SSBG funding is distributed to emergency domestic violence programs that provide emergency shelter services in the form of overnight shelter and congregate meals.

A “shelter night” is considered a unit rate for the indirect and direct costs expended per night, per client in the shelter facility. SSBG funding is the only funding source provided by ICJI that is solely dedicated to supporting domestic violence programs’ emergency shelter operations.

The DoW Kidney Cancer Early-Career Scholar Award is a unique initiative by the Academy of Kidney Cancer Investigators, established in FY19. It aims to foster innovative kidney cancer research through a mentoring program that pairs early-career scholars with experienced mentors. This program not only enhances research capabilities but also builds a robust network of kidney cancer researchers. By supporting promising scholars, the initiative aspires to advance the field and improve treatment outcomes for kidney cancer patients.

The NIAID aims to enhance our understanding of the interplay between chronic and infectious diseases through innovative precision systems biology research. By utilizing advanced technologies such as multi-omics and artificial intelligence, the initiative focuses on uncovering critical pathways that connect infections to chronic health issues. This multidisciplinary approach leverages longitudinal patient data to inform and improve prevention and treatment strategies, ultimately seeking to provide insights into disease progression and host-pathogen interactions.

The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses Grant

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and organizations actively participating in the warm-up ring (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) are invited to apply for a grant to support an increase in capacity and/or efficiency of programs aimed at adopting out retired Thoroughbred racehorses. 

Funding requests for this grant initiative should focus on:

Activities that increase capacity, decrease length of stay, reduce cost of care or increase efficiencies, and/or improve humane outcomes in other ways. Examples:

• Training programs
• Programs that engage new adopters and grow the market share for adoption
• Medical make-ready or rehabilitation with a focus on innovation and/or sustainability
• Collaborations with other equine industry organizations to increase support for retired racehorses

Proposals will be evaluated on their potential (within the 12-month grant term) to: 

• Increase capacity (the number of horses that can be rehabilitated, trained, and placed)
• Decrease length of stay
• Decrease cost of care
• Reduce risk, harm or suffering for retired racehorses

Requests may be for the creation of new programs or the expansion of existing programs. Programs that test innovative ideas are welcome.

Grant Amounts

Grants will generally range from $10,000-$40,000, with a maximum individual grant amount of $60,000. The total funding amount available for this grant opportunity is $200,000. 

Eligibility

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and active Warm-Up Ring participants (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) whose mission or operations focus significantly on serving retired Thoroughbred racehorses are eligible to apply for this grant opportunity. Adoption organizations must be up to date on reporting data biannually to the Equine Welfare Data Collective (EWDC). If you’re unsure about your eligibility, you may contact therighthorse@aspca.org to confirm before applying.   

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) was founded on the belief that animals are entitled to kind and respectful treatment by humans. We invite all voices to join us in working together to improve the lives of animals in need.

The ASPCA Right Horse Grants aim to enhance equine adoptions and support community equines by funding programs that boost shelter capacity or assist in keeping owned equines in their homes. Grants between $5,000 and $50,000 are available, with a total funding pool of up to $750,000. Eligible applicants include ASPCA Right Horse Adoption Partners and organizations committed to the welfare of retired Thoroughbred racehorses. Proposals should clearly outline the objectives and expected impacts.

Driving University Impact: Expanding the Public Exchange Network Grant

How the Public Exchange Network Works

No single university – even a large R1 – has enough faculty expertise available to meet the needs of every partner. The Public Exchange Network was designed to help universities work together seamlessly to build robust partnerships and generate more collective impact. Universities joining the network are independent but affiliated members, with full control over their own program and project portfolios. As a national network with local, on-the-ground capacity, Public Exchange Network members can also share approaches that work, scale solutions to common problems, and build cross-regional partnerships together. 

As an institutional partner in the Public Exchange Network, universities will build capacity to develop, test and implement solutions to the most urgent problems in their regions and beyond. Universities joining the Public Exchange Network get:

• The tools, templates and training they need to start right away;
• A shared brand they can plug into on day one;
• A network of faculty, past and potential partners and philanthropic relationships, benefitting everyone in the network. 

Public Exchange Network Expansion grants will cover 75-80% of the minimum estimated annual costs for two years to launch a new Public Exchange. To launch a Public Exchange, universities must have the following in place: (1) a staff executive director with experience launching and leading social impact partnerships, (2) a project seed fund, and (3) a modest operations budget. We also recommend some in-kind project management support from an existing university staff member. The grant includes a two-year Public Exchange Executive Director (ED) compensation subsidy of $300,000 to launch the Public Exchange on campus, and a 2-year license to use the Public Exchange brand. New Public Exchange Network members will also receive ongoing support and guidance from current Public Exchange leadership and staff at USC and WashU, including recruitment support and intensive training for hiring and onboarding an executive director, a sub-site on the Public Exchange website, incubation and project management support from current Public Exchange staff, and a suite of tools for developing and implementing Public Exchange projects.

The FY26 Neurofibromatosis Research Program's Synergistic Idea Award supports innovative research on neurofibromatosis (NF) through collaborative efforts of two or three Principal Investigators (PIs). By leveraging their unique perspectives, these PIs will tackle significant questions in NF research. Applicants must provide relevant preliminary or published data to support their proposals, ensuring a strong foundation for impactful research outcomes.

The DoW Neurofibromatosis Investigator-Initiated Research Award addresses critical needs in neurofibromatosis research, aiming to enhance patient care through innovative projects. It supports various research phases, excluding clinical trials, and encourages collaboration between scientists and clinicians. The funding mechanism includes two levels based on participation in optional features, such as the Open Science Initiative and collaboration with qualified partners, promoting data sharing and collaborative research efforts.

The FY26 Neurofibromatosis Research Academy – Scholar Award supports early-career independent investigators focusing on neurofibromatosis research. Scholars are required to be within 10 years of their terminal degree and must designate a Career Guide for mentorship, fostering collaboration. This initiative aims to advance impactful research and develop skilled researchers in a supportive environment, addressing critical areas of emphasis in neurofibromatosis research.

The FY26 Neurofibromatosis Research Program's Exploration-Hypothesis Development Award encourages innovative, high-risk research concepts in neurofibromatosis (NF). This award aims to support groundbreaking studies that will pave the way for future scientific inquiries. Proposals should present a well-defined, testable hypothesis grounded in sound scientific rationale. While preliminary data is encouraged, it is not a prerequisite for submission, allowing researchers to explore novel paradigms and perspectives in NF research.

The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.

About Henry L. Hillman Foundation

Henry L. Hillman Foundation inspires, invests in, and leverages great ideas to improve the quality of life in Pittsburgh and southwestern Pennsylvania.

Backup Power When Your Community Needs It

The Powered & Prepared Initiative seeks proposals from nonprofit and municipal organizations in southwestern Pennsylvania for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Southwestern Pennsylvania is increasingly impacted by severe weather events that cause widespread power outages and disruptions. The Powered & Prepared Initiative, supported by Henry L. Hillman Foundation, seeks proposals from nonprofit and municipal organizations for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Building the Future Workforce Challenge

Awarding $5 million and the opportunity to test bold, tech‑forward solutions that strengthen the advanced manufacturing and industry technician workforce—today and for the future.

About the Challenge

Caterpillar knows preparing the workforce for the future is urgent. Communities, employers, and industry need new ways to close advancing skill gaps. The Building the Future Workforce Challenge invites fresh perspectives from all sectors to rethink training. Up to five teams will be awarded $1 million each for sustainable, tech‑forward solutions that strengthen today’s—and tomorrow’s—advanced manufacturing and industry technician talent pipelines.

What types of solutions are you looking for?

The Building the Future Workforce Challenge aims to identify, test, and scale innovative, sustainable solutions that will address today’s and tomorrow’s advanced manufacturing and industry technician skill gaps. A core requirement of any solution is that it remains relevant amid evolving technology—ensuring that breakthrough innovation and human potential rise together.

Strong proposals for Building the Future Workforce Challenge will meet four criteria outlined in the scoring rubric, and proposed solutions must focus on one or more of the following solution categories for Building the Future Workforce Challenge:

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders 

There remains a scientific gap in understanding of the role of anti-TFP Imediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Geographic Scope

Brazil, China, Europe, Israel, Japan, Saudi Arabia, South Korea, Turkey, USA

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

Pediatric Hidradenitis Suppurativa Challenge Grant

Hidradenitis suppurativa (HS) is a devastating chronic inflammatory disease that manifests as recurrent painful nodules under the skin in the intertriginous areas of the body. It is associated with significant impacts on quality of life, psychosocial well-being, and long-term health outcomes of patients as well as consequences for families and caregivers. HS is prevalent, affecting between 1 and 4% of the population beginning in adolescence and persisting into adulthood. Despite the impact of HS, it remains underdiagnosed, undertreated, and understudied particularly in the pediatric and adolescent populations. Contributing to this dynamic are unknowns related to a complex disease etiology, stigma associated with HS symptoms (e.g., sweating, itching, and scarring commonly in the genital region), and limited treatment options to date with even fewer available for children under the age of 12.

To address the needs of children and adolescents living with HS, the Pediatric Dermatology Research Alliance (PeDRA), HS Connect, and the HS Foundation are offering the 2026 Pediatric HS Challenge Grant to support an early-to-mid career investigator for a one-year project focused on a high-priority, patient-centric research topic.

Focus

Proposals should address one or more of the following high-priority research topics:

• Predicting treatment effectiveness and risk utilizing real world evidence and/or experience
• Early disease and factors involved in severe disease development
• Optimizing surgical and procedural approaches to minimize pain, shorten healing time, and reduce recurrence
• Improving recruitment of diverse and representative populations for clinical studies, trials and advanced therapeutics

Funding:

• Up to $50,000 to support one year of research
• One award anticipated for this funding cycle