Best Pittsburgh Grants for Nonprofits in Pennsylvania

The Zero Suicide Initiative aims to enhance suicide prevention within Indian health systems by implementing the Zero Suicide framework. This program focuses on culturally informed strategies to empower Tribal health systems, fostering leadership, workforce development, and effective suicide risk identification. It emphasizes timely engagement and evidence-based treatment, ensuring continuity of care and quality improvement, ultimately enhancing outcomes for American Indian and Alaska Native individuals at risk for suicide.

The Behavioral Health Integration Initiative aims to enhance the health of American Indian and Alaska Native individuals by expanding access to integrated behavioral health care. It supports Tribal and Urban Indian Organization health systems in providing culturally responsive and trauma-informed services. The initiative focuses on improving care coordination, promoting early identification of mental health issues, and integrating various health services to improve overall health outcomes and quality of life for AI/AN communities.

American Academy of Family Physicians Foundation

The AAFP Foundation focuses on improving health for everyone, and your support makes an immediate impact on the good work we do—from leadership development and education scholarships to funding social and health care services.

The AAFP Foundation strives to create a sense of belonging through an inclusive environment that embraces the family medicine community by recognizing individual uniqueness and contributions to family medicine.

Richard D. Feldman, M.D. Student and Resident Essay Contest

Each year, the Center for the History of Family Medicine (CHFM) sponsors a contest to encourage medical students and family medicine residents to write scholarly essays relevant to the history of family medicine in the United States. The first-place winner will receive $2,000 and the second-place winner will receive a $1,000 award.

We encourage all to apply and are committed to developing scholarly essays relevant to the history of Family Medicine in the United States by medical students and residents who reflect the rich diversity of the specialty and the patients served.

American Brain Foundation

The American Brain Foundation funds research across the spectrum of the brain and nervous system, because it is our best hope for improving treatments, advancing prevention strategies, and discovering cures. Brain diseases, disorders, and injuries are interconnected. When we cure one, we will cure many.

Next Generation Research Grants

The American Brain Foundation’s Next Generation Research Grants (NGRGs) support early career investigators conducting high-quality research aimed at better understanding, treating, and curing brain diseases. These grants are offered in collaboration with disease-focused partner organizations and reflect ABF’s Cure One, Cure Many research philosophy: the belief that breakthroughs in one area of research accelerate progress across many others.

McKnight Clinical Translational Research Scholarship in Cognitive Aging and Age-Related Memory Loss

This award aims to support young investigators in clinical studies relevant to age-related cognitive decline and memory loss. The award also recognizes the importance of rigorous training in clinical research and encourages young investigators to seek opportunities to establish future careers in the area of human cognitive aging.

Please Note: The focus should NOT be on a neurodegenerative dementia (e.g., Alzheimer’s disease); however, proposals that focus on the combined study of cognitive aging and neurodegenerative cognitive changes may be considered.

For the purpose of this scholarship, research is defined as patient-oriented research conducted with human participants, or translational research specifically designed to develop treatments or enhance identification of age-related cognitive decline and memory changes. These may include epidemiologic or behavioral studies, clinical trials, studies of disease mechanisms, the development of new technologies, and health outcomes research. Disease-related studies not directly involving humans are also encouraged if the primary goal is the development of therapies, diagnostic tests, or tools to mitigate age-related cognitive decline and memory loss.

The ASPCA is offering up to $14 million in Spay/Neuter Grants for shelters and clinics across the U.S. to enhance spay/neuter services for vulnerable animals. Proposals can address critical infrastructure needs and major capital projects to increase spay/neuter capacity. Only one application per organization is permitted, and applicants must choose one funding category. The focus is on compelling proposals that meet the most urgent needs.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Andrew Wigton Memorial Scholarship

Andrew Wigton lost his young life in an automobile accident during his senior year at Pleasant High School. His parents and family created this scholarship in 2006 to honor his memory. Special consideration is given to applicants who have been members of the varsity basketball or varsity soccer team, two sports that Andrew loved.

In addition to memorial contributions, this fund is supported by the proceeds of the Dre 5K Run and a golf outing and by Andrew’s parents, friends, and family members.

Seniors of Pleasant High School in the upper 25th percentile of the graduating class are the focus of the Andrew Wigton Memorial Scholarship.

The NSF Core Research in Biological Sciences (BIO Core) program supports innovative research that enhances our understanding of biological systems, from molecular to biome scales. This funding opportunity encourages interdisciplinary proposals and can fund both single and multi-investigator projects. The awards will vary in scope and duration, accommodating exploratory projects and long-term commitments, depending on available funding and alignment with the program's objectives.

The FY 2026 funding opportunity aims to support Indian Tribes and intertribal consortia in implementing approved Nonpoint Source management programs under the Clean Water Act Section 319. This initiative, funded by the EPA, focuses on addressing NPS pollution through best management practices as outlined in Tribal NPS Management Program Plans, ensuring the protection of water resources and promoting sustainability in Tribal lands.

The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.

The National Science Foundation (NSF) is offering funding through the Engineering (ENG) program, focusing on foundational research in civil, mechanical, and manufacturing innovation. Key areas include advanced manufacturing systems, civil infrastructure, and intelligent dynamic systems. The NSF ENG encourages innovative and transformative proposals that may not require immediate commercial outcomes. Award sizes and durations will vary based on budget availability, aiming to support long-term research advancements.

The MPS Astronomical Sciences Research Programs, funded by the National Science Foundation, support innovative research in astronomical sciences. These initiatives aim to enhance our understanding of the universe through core research, technological advancements, and instrumentation. Topics include solar storm prediction, the discovery of exoplanets, and the study of black holes. Proposals should reflect ambitious, transformative ideas that may not require immediate practical outcomes, fostering long-term scientific exploration.

The NSF Expeditions in Computing program aims to foster transformative research in computer and information science. By funding projects up to $15 million over seven years, it encourages multidisciplinary teams to tackle ambitious research agendas that redefine the future of computing. The program supports innovative areas such as new architectures for intelligence, advanced robotics, and next-generation communication, emphasizing the importance of collaboration across various fields to achieve groundbreaking advancements.

The Emerging Frontiers in Research and Innovation (EFRI) program by the NSF aims to support transformative research in wave-based computing, fostering significant advancements in foundational engineering knowledge. With funding opportunities including EAGER awards and four-year grants up to $2 million, EFRI-WBC encourages interdisciplinary collaboration and innovative approaches to address strategic technology priorities. Proposals should articulate their potential long-term impacts on national science and technology missions, promoting a new era in computing methodologies.

The NSF MPS Chemistry Research Programs support groundbreaking research in chemical sciences, encompassing areas such as chemical catalysis, measurement, imaging, and theory. This initiative encourages innovative proposals that can lead to transformative advancements, without the necessity of immediate commercial applications. Researchers interested in exploring foundational concepts that could shape the future of chemistry are invited to submit their ideas for funding.

The National Science Foundation's Engineering Directorate (NSF ENG) promotes groundbreaking research in chemical, bioengineering, energy, and transport systems. Key programs include Chemical Process Systems, Engineering Biological and Biomedical Systems, Energy, Water, and Resource Engineering, and Transport Phenomena. NSF ENG seeks innovative, transformative proposals that push the boundaries of foundational research, regardless of immediate commercial applications, and emphasizes diverse funding opportunities based on availability.

The MPS Materials Research Programs, funded by the National Science Foundation, aim to enhance the understanding of materials and their diverse applications. These programs cover areas such as biomaterials, ceramics, condensed matter physics, and electronic materials. With an emphasis on transformative research, NSF MPS encourages proposals that are innovative and foundational, without the necessity for immediate commercial outcomes, fostering long-term advancements in materials science.

The BJA FY 2026 Kevin and Avonte Program aims to reduce the injuries and fatalities of individuals with dementia and developmental disabilities who wander from safe environments. This funding opportunity supports law enforcement and public safety agencies in implementing locative technologies to track missing individuals and develop programs that enhance safety and facilitate rescues, ultimately ensuring the well-being of vulnerable populations.

The ADCMS Competitive Grant Program, administered by the DOT Federal Highway Administration, aims to incentivize eligible State Departments of Transportation and partners to implement innovative technology in construction projects. This initiative promotes collaboration among various entities, including local governments and private industries, with a required cost share of 20% to enhance project viability and effectiveness. The program encourages joint applications to maximize the impact of technological advancements in the construction sector.

The Cold Chain Grants for Emergency Food Assistance, funded by the Agricultural Marketing Service, aim to support eligible organizations in enhancing cold storage capabilities within the food supply chain. This initiative focuses on providing essential nutrition assistance to low-income individuals through subawards to food banks and nonprofit organizations. By investing in cold storage equipment, the program seeks to improve the management and distribution of food resources, ensuring that vulnerable populations receive adequate support.

The BJA FY 2026 Second Chance Act aims to enhance education and employment opportunities for adults and youth transitioning from incarceration. By funding state, local, and tribal governments, as well as community organizations, this initiative seeks to improve academic and vocational training in prisons. The program focuses on developing marketable skills, leveraging technology, and aligning with local job markets to foster job readiness, improve employment outcomes, and reduce recidivism.

The BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Site-Based Program aims to combat the rising crisis of substance use and overdose deaths. This funding opportunity supports state, local, territorial, and tribal governments in implementing comprehensive responses, including law enforcement initiatives, prevention programs, and recovery services. Applications are due by October 1, 2026, providing a crucial chance to enhance community safety and health through targeted interventions.

The BJA FY 2026 Second Chance Act Family-Based Substance Use Disorder Treatment Program aims to provide essential treatment and recovery support services for parents with substance use disorders (SUD) who have minor children or are pregnant. Eligible applicants include state, local, tribal governments, and nonprofit organizations, which can apply for funding to implement family-based programs in various settings. This initiative seeks to reduce recidivism and enhance reentry outcomes for both parents and their children.

The ONR FY27 Young Investigator Program invites cutting-edge research proposals in priority areas that align with the interests of ONR Program Officers. This federal funding opportunity aims to support innovative projects led by early-career researchers, fostering advancements in science and technology relevant to the Navy. Interested applicants can find detailed eligibility criteria and contact information on the ONR website, encouraging collaboration and engagement in impactful research.

The BJA FY 2026 Local Law Enforcement Crime Gun Intelligence Center Integration Initiative aims to support law enforcement agencies in establishing and expanding Crime Gun Intelligence Centers (CGICs). This initiative encourages interagency collaboration for the effective management and analysis of crime gun evidence, enhancing the ability to swiftly identify crime guns and their sources. In partnership with the ATF, this program seeks to reduce firearm-related crime and improve prosecution outcomes.

The Amy Adina Schulman Memorial Fund

The Amy Adina Schulman Memorial Fund is a Princeton, New Jersey-based endowment fund providing grants to individuals, young adults who volunteer or intern for progressive social action projects or programs in an area of their interest and commitment. The Amy Adina Fund also sponsors a lecture each year on a relevant and timely topic related to its educational mission.

The Amy Adina Schulman Memorial Fund was started in 1987 one year after Amy Adina, 20, died suddenly while a student and activist at Rutgers University. It is a realization of her family and her communities’ desire to celebrate her life, to fulfill her dreams and her potential. Since its inception, almost 1,500 grants have been awarded for work in Africa, Asia, Latin America, the Middle East, and the United States—nearly $1,000,000 in total. The Amy Adina Schulman Memorial Fund is a 501(c)3 nonprofit organization.

About Our Grants

Small grants (depending on length of service), are awarded to as many applicants as possible rather than giving larger amounts to fewer individuals. The number of awards has grown each year thanks to annual contributions as well as to gifts sent to the Fund to honor special occasions and life cycle events.

The Fiscal Year 2027 AmeriCorps Seniors RSVP Competition invites communities to apply for funding aimed at engaging adults aged 55 and older in addressing pressing local needs. Through national service and volunteerism, AmeriCorps strengthens communities and fosters civic engagement. This open competition spans all states and territories, encouraging organizations to harness the skills and expertise of older adults to enhance community well-being and promote a culture of service.

The OVC FY 2026 Services for Victims of Human Trafficking aims to enhance victim service programs across the United States. This initiative supports victims by providing critical services to address their diverse needs, including mental health support and assistance with legal challenges. By funding comprehensive programs, the Office for Victims of Crime seeks to combat human trafficking effectively and promote recovery for affected individuals, ensuring their rights and well-being are prioritized.