Best Pittsburgh Grants for Nonprofits in Pennsylvania

The NIH Common Fund Data Ecosystem aims to enhance the reusability of biomedical data through collaboration between Common Fund programs and external data resources. This funding opportunity encourages projects that connect various biomedical data ecosystems, including the HEAL Data Ecosystem and the BRAIN Initiative. By fostering partnerships, the initiative seeks to improve the accessibility and interoperability of valuable datasets, ultimately advancing research efforts. Note that clinical trials are excluded from this funding opportunity.

The Domestic Violence Prevention (DVP) grant from the IHS aims to enhance the capacity of Tribes and Urban Indian Organizations to combat domestic and sexual violence. This initiative promotes culturally appropriate, trauma-informed services, focusing on victim advocacy and collaboration across sectors. It addresses critical issues like human trafficking and child maltreatment, ensuring long-term sustainability through evidence-based practices and data sharing, ultimately improving community health and safety for AI/AN populations.

The Urban Indian Health 4-in-1 Program is designed to enhance the health and well-being of urban Native Americans through targeted initiatives in immunization, health promotion, disease prevention, mental health support, and addressing alcohol and substance abuse issues. Funded by the US Dept. of Health & Human Services, this program aims to improve access to essential health services and foster healthier communities among urban Indian populations.

The Youth Regional Treatment Center Aftercare Program aims to support American Indian and Alaska Native youth in maintaining safety, sobriety, and success post-discharge from Youth Regional Treatment Centers. This initiative enhances culturally relevant, community-based aftercare by fostering care coordination, building partnerships, and addressing barriers to improve youth outcomes.

The Urban Indian Health Program - Education & Research collaborates with the US Dept. of Health & Human Services to enhance educational and research opportunities for urban Indian populations. This initiative aims to address health disparities and ensure that urban Indians have access to quality health services and information. By partnering with various urban Indian organizations, the program fosters community engagement and empowers individuals through education and research, ultimately improving health outcomes.

The CAFE Group 

We resource leaders, invest in their genius, and bring people together to reimagine what philanthropy can do.

Founded by Liz and Don Thompson, The CAFE Group is a national nonprofit transforming how change is resourced. 

With a focus on education equity, social capital, and philanthropic transformation, we pair catalytic funding, community-rooted leadership development, and cross-sector collaboration to strengthen the people and institutions shaping a more just future. Everything we do is grounded in relationship, because we believe the way resources move matters just as much as where they land.

The 1954 Project Luminary Award

The 1954 Project Luminary Award celebrates transformational education nonprofit leaders dedicated to serving Black students and communities through powerful investments in their organizations' ability to create lasting change.

The Luminary Experience

Each Luminary organization gets more than funding. Through The 1954 Project, leaders gain a community, a platform, and space to grow with tailored support over the course of the three year journey.​

• $1 Million, Unrestricted: Catalytic funding to expand what’s working.
• Leadership Coaching + Capacity Support: Guidance from peers and experts who are committed to helping you build a lasting, impactful organization.
• National Network: Luminaries join a powerful community of innovators, change-makers, and visionaries driving systemic progress to support students and communities across the U.S.

The 1954 Project’s Impact Areas

We focus on three interconnected areas critical to advancing equity:

• Innovation in Teaching and Learning: Create education models that center Black students through culturally affirming approaches that challenge traditional structures and transform how learning happens, ultimately serving all students. 
• Diversity in Education: Build pathways that increase and sustain Black educators and education leaders who transform where and how students learn.
• Pathways to Economic Mobility: Build pathways to wealth, ownership, and economic power for Black students, families, and communities through innovative educational programming.

Our Selection Criteria

We seek out extraordinary applicants who embody our values and vision across three categories:

Leader: We look for leaders whose influence and vision contribute to the collective well-being and advancement of the Black community. These leaders:

• Are Visionary: They demonstrate a strategic and pragmatic mindset, articulating a transformative vision for significant, positive change.
• Show Demonstrated Commitment: They embody steadfast dedication to your cause, inspiring and influencing others, and galvanizing community involvement.
• Are Adaptive: They assertively tackle challenges, turning setbacks into opportunities for innovation, while maintaining humility and thoughtfulness in problem-solving.

Organization: We look for organizations that drive significant change, anchored by a deep love for people and driven by the genius within communities of color. These organizations: 

• Have a Defined Problem: They clearly identify the issue they are addressing and explain in detail how your organization tackles root causes. 
• Take a Strategic Approach: They have clear, measurable, and achievable organizational goals with a well-defined strategy informed by thorough analysis. 
• Show Demonstrated Impact: They have a tested model that has produced positive results, incorporating continuous learning and iteration. 
• Have a Transformation Plan: They present a clear plan for using the $1M award to advance your organization's mission, vision, and long-term goals. 
• Embrace Collaboration: They use collaborate to build partnerships based on trust, love, and common goals. 

Radical Imagination: We seek leaders who challenge and redesign societal norms to build a just and equitable future. They demonstrate:

• Community-Rooted Leadership: They maintain and cultivate genuine community ties, integrating professional expertise and personal commitment to drive visionary, impactful strategies. 
• Long-Term Commitment: They are in it for the long haul, committing to sustained impact across generations and prioritizing long-lasting solutions over short-term gains. 
• Collectivism: They embody the philosophy of "I am because we are," actively engaging in collaborative networks and fostering community-reflective solutions. 

Foundation for Children with Intellectual and Developmental Disabilities

The FCIDD was founded for the purpose of providing support to organizations that serve individuals with intellectual and developmental disabilities.

Mission Statement: The Foundation supports organizations which enhance the lives of persons with intellectual and developmental disabilities by promoting research, projects, education and advocacy. 

Nonprofit Project Grants

The Foundation for Children with Intellectual and Developmental Disabilities (FCIDD) funds 501(c)(3) organizations working with individuals with intellectual and developmental disabilities of all ages, primarily in the states of Maine, New Hampshire, Vermont, Massachusetts, Rhode Island, Connecticut, New York, New Jersey, Pennsylvania, Ohio, West Virginia, Delaware, Maryland, the District of Columbia, and Virginia. 

Funding Priorities

• Grants will be awarded for the purpose of primarily benefiting, including, or increasing accessibility for individuals with intellectual or development disabilities.
• Grants may be awarded for scholarships or training personnel in the care and education of individuals with developmental and/or intellectual disabilities. 
• Grants shall mainly be distributed to a Charity whose primary purpose or whose project is to support individuals with intellectual or developmental disabilities. A Charity which has a project to benefit individuals with developmental or intellectual disabilities based on financial need shall be awarded the grant money based upon its own objective criteria and without any special preference to members of Civitan or members of their family.

Grant Categories

A grant application typically fits into one of the following categories: Accessibility & Engagement; Educational Spaces; Program Area Improvements; Outreach and Education 

Accessibility & Engagement

For museums, parks, other public spaces without a specific I/DD focus wanting to make property or equipment improvements and additions to better include visitors with I/DD.

Foundation for Children with Intellectual and Developmental Disabilities

The FCIDD was founded for the purpose of providing support to organizations that serve individuals with intellectual and developmental disabilities.

Mission Statement: The Foundation supports organizations which enhance the lives of persons with intellectual and developmental disabilities by promoting research, projects, education and advocacy. 

Nonprofit Project Grants

The Foundation for Children with Intellectual and Developmental Disabilities (FCIDD) funds 501(c)(3) organizations working with individuals with intellectual and developmental disabilities of all ages, primarily in the states of Maine, New Hampshire, Vermont, Massachusetts, Rhode Island, Connecticut, New York, New Jersey, Pennsylvania, Ohio, West Virginia, Delaware, Maryland, the District of Columbia, and Virginia. 

Funding Priorities

• Grants will be awarded for the purpose of primarily benefiting, including, or increasing accessibility for individuals with intellectual or development disabilities.
• Grants may be awarded for scholarships or training personnel in the care and education of individuals with developmental and/or intellectual disabilities. 
• Grants shall mainly be distributed to a Charity whose primary purpose or whose project is to support individuals with intellectual or developmental disabilities. A Charity which has a project to benefit individuals with developmental or intellectual disabilities based on financial need shall be awarded the grant money based upon its own objective criteria and without any special preference to members of Civitan or members of their family.

Grant Categories

A grant application typically fits into one of the following categories: Accessibility & Engagement; Educational Spaces; Program Area Improvements; Outreach and Education 

Educational Spaces

For I/DD serving school programs with a 501(c)(3) or 501(c)(4) attached needing property improvements or equipment/resource purchases to better serve their students with I/DD.

Foundation for Children with Intellectual and Developmental Disabilities

The FCIDD was founded for the purpose of providing support to organizations that serve individuals with intellectual and developmental disabilities.

Mission Statement: The Foundation supports organizations which enhance the lives of persons with intellectual and developmental disabilities by promoting research, projects, education and advocacy. 

Nonprofit Project Grants

The Foundation for Children with Intellectual and Developmental Disabilities (FCIDD) funds 501(c)(3) organizations working with individuals with intellectual and developmental disabilities of all ages, primarily in the states of Maine, New Hampshire, Vermont, Massachusetts, Rhode Island, Connecticut, New York, New Jersey, Pennsylvania, Ohio, West Virginia, Delaware, Maryland, the District of Columbia, and Virginia. 

Funding Priorities

• Grants will be awarded for the purpose of primarily benefiting, including, or increasing accessibility for individuals with intellectual or development disabilities.
• Grants may be awarded for scholarships or training personnel in the care and education of individuals with developmental and/or intellectual disabilities. 
• Grants shall mainly be distributed to a Charity whose primary purpose or whose project is to support individuals with intellectual or developmental disabilities. A Charity which has a project to benefit individuals with developmental or intellectual disabilities based on financial need shall be awarded the grant money based upon its own objective criteria and without any special preference to members of Civitan or members of their family.

Grant Categories

A grant application typically fits into one of the following categories: Accessibility & Engagement; Educational Spaces; Program Area Improvements; Outreach and Education 

Program Area Improvements

For I/DD specific 501(c)(3) or 501(c)(4) looking to add/improve programming potential via equipment and property improvements, updates and additions.

The FCIDD Nonprofit Project Grants are designed to support 501(c)(3) organizations working with individuals with intellectual and developmental disabilities across various states. Grants are awarded for projects that enhance accessibility, provide educational opportunities, and promote community engagement. The foundation encourages collaboration with local Civitan clubs, particularly in October and March funding rounds, while also offering open applications in July. The initiative aims to empower nonprofits to improve the lives of individuals with developmental disabilities.

The 2026 National Urban and Community Forestry Challenge Cost Share Grant Program aims to tackle economic, health, and environmental issues in communities through innovative tree resource utilization. By transforming wood from various sources into valuable products like lumber and biochar, this initiative promotes local economies and enhances community resilience. Projects should align with community forestry plans, adhere to safety standards, and provide job creation opportunities, ultimately fostering sustainable urban forest management and utilization.

The Healthy Tomorrows Partnership for Children Program (HTPCP) aims to enhance access to essential preventive clinical and public health services for children through community-driven initiatives. Funded by the US HHS: Health Resources & Services Administration (HRSA), this program focuses on empowering local communities to implement effective strategies that improve children's health outcomes and promote overall well-being. Projects funded under this initiative will play a vital role in ensuring healthier futures for children.

The Alliance for Innovation on Maternal Health (AIM) program aims to enhance maternal health outcomes by providing technical assistance across all U.S. states and territories. This initiative focuses on implementing best practices to improve safety during childbirth, ultimately saving lives. By supporting jurisdictions and birthing facilities involved in AIM, the program seeks to promote quality improvements in maternal health care, ensuring safer births and better health for mothers and infants.

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

• Promote and support legal research and education;
• Advance the science of jurisprudence;
• Facilitate the administration of justice;
• Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Pathways to the Profession Grant

The Pathways to the Profession Grant Program is designed to support educational, community service, or outreach projects and initiatives that support pathway programs and events that encourage high school, college and law school students, and newer lawyers, particularly those from underrepresented backgrounds, to pursue and succeed in a legal career through educational, networking, mentorship programs and other opportunities. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity) and other organizations to develop and support projects that make a lasting impact on their communities.

Applicants may only receive one (1) Foundation grant per year.

About

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Rett Syndrome (RS) Fund

Help with healthcare costs for Rett syndrome.

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. Check your eligibility with our quick and easy tools below. If this fund is open, apply today for an instant approval decision and use your grant funding right away

About the disease

Rett syndrome (RS or RTT) is a rare, genetic neurological disorder that causes a loss of motor and spoken language skills, as well as other physical and neurologic impairments early in life.

Diagnosis codes

F84.2

The Pulmonary Hypertension Fund, supported by the Patient Advocate Foundation, offers financial assistance for patients dealing with pulmonary hypertension. This fund covers essential healthcare costs, including medication copays and health insurance premiums. Patients must meet specific eligibility criteria, such as having a confirmed diagnosis and appropriate health insurance. Since 1996, the foundation has empowered millions to navigate healthcare challenges, ensuring they receive the care they need without financial burden.

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

• Promote and support legal research and education;
• Advance the science of jurisprudence;
• Facilitate the administration of justice;
• Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Community Outreach Grant

The Community Outreach Grants Program is designed to support projects and initiatives that provide legal services in local communities. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity) and other organizations to develop and support projects that make a lasting impact on their communities.

Applicants may only receive one (1) Foundation grant per year.

The Primary Biliary Cholangitis (PBC) Fund, established by the Patient Advocate Foundation, offers vital financial assistance to patients managing the costs of treatment for primary biliary cholangitis. This fund covers out-of-pocket healthcare expenses such as medication copays and health insurance premiums, enabling individuals to access necessary treatments. Since its inception, the foundation has empowered millions by providing personalized support and resources, aiming to improve patient care and health outcomes.

The Pompe Disease Health Equity Fund, supported by the Patient Advocate Foundation, offers crucial financial assistance to patients diagnosed with Pompe disease. This fund helps cover out-of-pocket healthcare costs, including medication copays and health insurance premiums. Eligibility requires a confirmed diagnosis and treatment plan, along with meeting specific income criteria. With a mission to enhance health equity, the fund empowers patients to access necessary care and improve their quality of life.

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

• Promote and support legal research and education;
• Advance the science of jurisprudence;
• Facilitate the administration of justice;
• Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Civics Education Grant

The Civics Grant Program is designed to support projects and initiatives that promote a wider public understanding of democratic principles, the judicial system and the rule of law. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity), and other organizations to develop and support projects in their communities that foster public understanding of the rights and responsibilities of American citizenship, particularly among younger Americans.

Applicants may only receive one (1) Foundation grant per year.

The Pompe Disease Fund, supported by the Patient Advocate Foundation, offers vital financial assistance to individuals diagnosed with Pompe disease. This fund covers out-of-pocket healthcare costs including medication copays and health insurance premiums. Eligible patients must have a confirmed diagnosis and be receiving treatment or planning to start within 60 days. With over 3.8 million patients helped since its inception, the fund aims to alleviate financial burdens and enhance access to necessary treatments.

Founded in 2016, this program supports nonfiction filmmakers or filmmaking teams working on their first or second feature-length documentary.

In this year-long program, 9 filmmakers will receive:

• $40,000 USD in grant funding for the production of their feature-length film
• Mentorship with Chicken & Egg Films team members
• Two creative retreats focused on career building and creative development
• Travel stipend for director and producer upon acceptance to a forum or market during program year
• Tailored industry meetings and funder connections
• Peer support from their cohort

You do not need a fiscal sponsor to apply for the (Egg)celerator Lab. However, if you are selected for the Lab, you must secure a US fiscal sponsor, or be a 501(c)(3), to receive the funds. If granted, we can help advise on finding a fiscal sponsor. 

Syndax Pharmaceuticals, Inc.

At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. We believe that it takes a community to build a great medicine, and that is why we are working to set the new standard for developing medicines in the field of oncology – one that revolves around collaboration, shared learning, and excellence.

Syndax’s mission is to obtain regulatory approval and commercialize drugs that extend and improve the lives of cancer patients by drawing on the newest scientific research and advances, collaborating with determined problem solvers, and identifying value in overlooked aspects of science.

Educational Funding

At Syndax, we are committed to the goal of supporting objective, balanced and scientifically rigorous education that furthers improvements in science, medicine, and patient care. We accomplish this goal, in part, by providing grants for independent medical education (IME) programs. These can include live, online, and/or enduring programs that educate healthcare providers (HCPs), patients, or caregivers. Programs that are funded via Syndax medical education grants must be primarily dedicated, in both effort and time, to medical, health or scientific topics that are objective, balanced, unbiased, and scientifically rigorous. Medical education grants must never be made with the intent to directly or indirectly reward, influence or encourage the recipient to prescribe, purchase, sell or arrange for any Syndax product.

The Law School Admission Council, Inc. (“LSAC”) is committed to promoting access in legal education and the legal profession. The LSAC Pathway Grant (the “Grant”) program makes awards to nonprofit institutions for programming focused on one or more of the following strategic goals:

• Goal 1: Early Access/Outreach - Introducing the law and careers in law to students, particularly students facing access and opportunity barriers to information and education, before high school graduation
• Goal 2: Supporting Admissions - Ensuring all applicants, including applicants facing access and opportunity barriers to information, education, and other supports/resources, have access, opportunity, and support in the law school admission process
• Goal 3: 1L Retention - Reducing attrition rates and increasing persistence for law students after the first year of law school, particularly students facing access and opportunity barriers to information, education, and other supports/resources

About

Chicken & Egg Films shapes a more equitable and just world with the catalytic power of documentary films by providing funding, mentorship and industry access to a global community of women and gender-expansive filmmakers. Founded in 2005 by Julie Parker Benello, Wendy Ettinger, and Judith Helfand, and helmed today by CEO Jenni Wolfson, our goal is to disrupt and dismantle barriers to filmmaking caused by gender bias.

Research & Development Grant

Now in its fourth year, the Research & Development Grant supports filmmakers from around the world who have directed at least one feature-length documentary and are in the research & development stage of their next feature-length film.

With continued grant-making support by Netflix, the Research & Development Grant supports directors to ideate and plan for their next feature-length film. Many filmmakers invest their personal resources into their films and face funding challenges when entering into the research & development stages of new projects. It is hard to secure funding for a new project without significant sample material, yet producing material without external funding can be almost impossible. To address this challenge, the Research & Development Grant provides financial support to directors during a filmmaking stage that is too often unpaid and unsupported. 

A total of $450,000 USD will be awarded in the following grant amounts:

• $10,000 USD grants for Research
• $20,000 USD grants for Development

The final number of Research Grants vs. Development Grants disbursed will be determined during the selection process, based on the characteristics and strength of the applicant pool for each category.

The purpose of the Research & Development Grant is to support projects at the early stages of their lifecycle. If you have already raised a significant amount of capital (over 35% of your film’s total budget) and have shot and/or edited a substantial amount of footage, you may not be competitive for this grant, unless you can demonstrate very specific needs for the project (such as previously overlooked research activity). 

We have separated the Research Grant from the Development Grant to allow early-stage projects to receive support without the need to submit all the deliverables required for projects in the development phase. 

We recognize that each documentary is unique and that processes for research and development, fundraising, and production can vary widely. The information provided here is not intended as strict eligibility criteria, but rather as general guidelines to help applicants understand the stage at which we aim to provide support for projects. 

The 2026 Chicken & Egg Films Research & Development Grant is generously supported by Netflix.