Best Addiction and Substance Abuse Grants in Puerto Rico

The HEAL Initiative aims to identify new druggable targets for pain within the understudied proteome. This funding opportunity invites applications for pilot projects that generate preliminary data and tools for exploring these targets. The initiative seeks to enhance research on understudied proteins related to pain management, providing essential funding for biochemical and biological work. This NOFO is part of the NIH's broader effort to develop novel medications that address various aspects of opioid addiction and its consequences.

The NIAAA Integrative Neuroscience Initiative on Alcoholism (INIA) aims to renew support for two research consortia focusing on the biological mechanisms of excessive alcohol consumption and Alcohol Use Disorder (AUD). By utilizing advanced technologies and fostering collaboration across multiple sites, this initiative seeks to standardize neurofunctional measures and enhance reproducibility in findings. Investigators are encouraged to prepare for future applications to this NOFO, which will utilize the U24 activity code.

The Academic Research Enhancement Award (AREA) supports small-scale research grants for institutions with limited NIH funding, emphasizing biomedical research experiences for undergraduates. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over the past seven years. This initiative aims to enhance the research environment at these institutions, fostering student involvement in research activities.

The Siletz Tribal Charitable Contribution Fund, established by the Confederated Tribes of Siletz Indians, has distributed over $16.3 million in grants since 1999. It supports charitable organizations and local governments in eleven Oregon counties, as well as Native American initiatives across the U.S. The fund prioritizes education, health, public safety, addiction prevention, housing, arts, and environmental preservation, ensuring the Tribe's commitment to community support and cultural heritage.

The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.

The HEAL Initiative aims to address the complex interplay between chronic pain and opioid use disorder (OUD), affecting 40-60% of OUD patients. Through the IMPOWR initiative, this funding opportunity seeks to develop integrated care strategies that enhance treatment delivery at health systems levels. By identifying effective interventions and collaborative care models, the initiative strives to improve patient outcomes in managing both chronic pain and OUD, while emphasizing the roles of various healthcare professionals in this integrated approach.

The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.

The OJJDP FY 2026 Community and Schools Youth Drug Prevention Program aims to combat youth substance use through comprehensive prevention strategies. This initiative invites applications from states, local governments, and nonprofit organizations to develop programs that educate and support youth in schools and community settings. By fostering collaboration with law enforcement and community coalitions, the program seeks to build capacity and implement effective interventions to protect the well-being of American youth.

The OJJDP FY 2026 Juvenile Drug Treatment Court Program aims to enhance juvenile drug treatment courts (JDTCs) across the U.S. by supporting states, local courts, and Tribal governments. This initiative focuses on improving outcomes for youth dealing with substance use disorders or co-occurring mental health issues. The program underscores the commitment of the Office of Justice Programs to strengthen community safety and provide vital resources for effective intervention and support.

The BJA FY 2026 Veterans Treatment Court Program aims to enhance operations for veterans in the criminal justice system, focusing on reducing substance use, including opioids and alcohol. It integrates treatment for substance use and mental health disorders within a judicial framework, targeting high-risk veterans. This initiative not only addresses public safety concerns but also aims to provide necessary support and resources for veterans dealing with issues like PTSD and traumatic brain injury, fostering rehabilitation and recovery.

The BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Training and Technical Assistance (TTA) aims to enhance the capacity of grantees through dedicated training. It addresses critical operational issues related to overdose responses, targeting illicit opioids and stimulants. The program underscores the U.S. Department of Justice's commitment to public safety, law enforcement support, and the fight against substance misuse. Applications are due by November 9, 2026.

The BJA FY 2026 Adult Treatment Court Program aims to enhance Adult Treatment Court operations, focusing on preventing overdoses and reducing substance use among high-risk adults in the criminal justice system. The program integrates judicial supervision, substance use disorder treatment, and recovery support services to improve outcomes for participants. This funding opportunity from the U.S. Department of Justice highlights the commitment to public safety and addressing critical issues like the opioid crisis.

The NIDA Avenir Program aims to cultivate innovative leaders in addiction science by funding exceptional early stage investigators (ESIs) embarking on pioneering research. Launched in 2015, this initiative encourages high-risk, high-reward mechanistic studies related to Substance Use Disorders (SUDs) across diverse scientific domains. Applications from new investigators and those outside addiction research are welcomed, fostering interdisciplinary approaches that enhance understanding of SUD mechanisms. The program supports ESIs who may lack preliminary data but demonstrate potential for impactful contributions.

The Building Communities of Recovery program aims to enhance access to long-term recovery support for individuals facing substance use disorders and co-occurring mental health issues. By empowering organizations to mobilize community resources, this initiative fosters a collaborative environment that promotes sustained recovery. Funded by the Substance Abuse and Mental Health Services Administration, the program emphasizes the importance of community connections in the recovery process, ensuring that individuals receive the support they need to thrive.

The State Pilot Program for Treatment for Pregnant and Postpartum Women aims to enhance the state's capacity to deliver integrated and evidence-based services for substance use disorders and maternal mental health. The initiative focuses on supporting pregnant and postpartum women and their families, ensuring they receive comprehensive care tailored to their unique needs. Funded by the Substance Abuse and Mental Health Services Administration, this program is a vital step toward improving health outcomes for vulnerable populations.

The Emergency Department Alternatives to Opioids Program aims to implement practices that offer alternatives to opioid treatments in hospitals. This initiative focuses on reducing the harmful consequences of opioid use for pain management, promoting safer treatment options, and minimizing the risk of opioid misuse and overdose. Specifically, it targets healthcare organizations to enhance their pain care strategies, ultimately contributing to better patient safety and health outcomes.

The Providers Clinical Support System – Universities program aims to equip graduate-level health professional students with the necessary skills to understand, identify, intervene, and treat patients with substance use disorders. By focusing on practical training and comprehensive education, this initiative prepares future practitioners to effectively address the challenges associated with substance misuse, ensuring they are well-prepared upon obtaining their licenses.

The Rural Communities Opioid Response Program - Evaluation aims to assess the effectiveness of behavioral health strategies in rural settings. By developing evaluation tools and resources, this initiative seeks to empower local communities in their health initiatives, ensuring that future programs are informed by comprehensive evaluations. Funded by the Health Resources and Services Administration, the program highlights the importance of tailored approaches to address opioid-related challenges in rural areas.

The CDC has announced funding for FY 2027 to enhance state capacity in alcohol epidemiology and prevent excessive alcohol use through the NOFO CDC-RFA-DP-27-0072. This initiative aims to equip states with essential tools and knowledge for effective public health measures against excessive alcohol use, a major preventable cause of death in the U.S. The program will also provide expert technical assistance and training on effective prevention strategies over a 5-year performance period.

The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.

The Tobacco Centers of Regulatory Science (TCORS) program, supported by the NIH and FDA, aims to foster research centers that enhance the scientific understanding of tobacco regulation. These centers will conduct hypothesis-driven projects on critical topics such as addiction, health effects, and marketing. By providing a multidisciplinary approach, TCORS seeks to inform public health strategies and ensure effective implementation of the Family Smoking Prevention and Tobacco Control Act.

The CDC's NCIPC is seeking research proposals to tackle implementation challenges in providing linkage to care services for individuals with opioid use disorder (OUD). This initiative encourages partnerships with public health entities and local healthcare champions to create actionable, evidence-based strategies. The goal is to enhance care access and ensure comprehensive overdose prevention services are available in real-world healthcare settings, thereby improving outcomes for those at risk of opioid overdose.

The ASCAP Foundation Mariana & Paul Williams "Sunlight of the Spirit" Award supports organizations dedicated to addiction recovery through music. Established by the ASCAP Foundation and Paul Williams, the award recognizes efforts that improve lives affected by addiction. Eligible nominees must be 501(c)(3) organizations with a commitment to music-based recovery. The award includes a $5,000 prize to further their impactful work in the community, fostering healing through the therapeutic power of music.

The Innovation in Behavioral Health (IBH) Model (the “Model”) is an eight-year, voluntary service delivery and payment model promoting integrated care in behavioral health (BH) settings. The IBH Model will test the impact of a value-based payment (VBP) model aligned across Medicaid and Medicare that supports an integrated care delivery framework in specialty BH organizations and settings for adult Medicaid, Medicare, and dually eligible beneficiaries with moderate to severe mental health conditions and/or substance use disorders (SUDs).The Centers for Medicare & Medicaid Services (CMS), through its Center for Medicare & Medicaid Innovation (Innovation Center), will select up to eight state Medicaid agencies (SMAs) to participate in the Model. Implementation will begin in January 2025 and end in December 2032. The Model will have an eight-year performance period, which will be comprised of a three-year Pre-Implementation Period along with a five-year Implementation Period. Up to $7.5 million dollars in cooperative agreement award funding will be available to each selected Recipient over the course of the eight years. 

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

About Samba RecoverySamba Recovery is dedicated to empowering individuals recovering from alcoholism and drug addiction by restoring confidence and fostering resilience. Through a foundation of compassion, support, and holistic care, we guide individuals toward renewed health and wellness, meaningful relationships, and the discovery of their inner strengths—assisting them to achieve their fullest potential.Hope for Addiction ScholarshipSamba Recovery’s Hope for Addiction Scholarship is an annual $1,000 award dedicated to encouraging more young people to join the fight against addiction by pursuing degrees that directly support individuals and families affected by substance use disorders.

We welcome applications from all eligible students, with special encouragement for those who are in recovery themselves or who have been impacted by addiction within their families.Application requirements:

• Proof of college enrollment or acceptance
• Pursuing a degree with the goal of working with individuals and/or families impacted by addiction
• Completed application form
• An original 500 to 1000 word essay on how you are planning to use your degree to help individuals and families struggling with addiction, and why helping those affected by substance use disorder is important to you

The HEAL Initiative's Career Development Awards aim to empower early career researchers and clinicians in implementation science. By providing training and funding, this initiative seeks to address substance use prevention and treatment through research projects that align with the HHS Overdose Prevention Strategy. Focused on vital areas such as opioid prescribing, OUD treatment, and recovery support, the program aspires to cultivate a new generation of experts who will significantly impact addiction clinical practices and mentorship.