Best Rapid City Grants for Nonprofits in South Dakota

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For technically ambitious or higher-risk, earlier-stage concepts focused on feasibility testing, assay or workflow prototyping, and initial cost-reduction validation. Intended approaches that require focused development to demonstrate viability.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For concepts with preliminary feasibility evidence that are ready to advance from prototype toward an integrated workflow—optimizing performance, broadening assay or pathogen coverage, and generating more robust cost-reduction and performance data.

Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows

Catalyzing Innovation through Partnerships

At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.

About this Challenge

This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).

Award Structure and Funding Level

To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:

For more mature concepts aimed at workflow refinement, performance optimization, and generation of proof-of-concept and validation data in relevant public-health use cases in LMICs.

About The American Chestnut Foundation:

Our mission is to return the iconic American chestnut to its native range.

Our vision is a robust eastern forest returned to its splendor.

Small Grants Program

Are you looking for funding to support your American chestnut research? External small grants offer recipients a variety of benefits such as professional development and an expanded network. Grant activities contribute to the continuous renewal and development of faculty and staff, to the education and motivation of students, and achievement of our mutual interest — restoration of the American chestnut. This is a small grants program. TACF does not ordinarily fund projects in excess of $10,000.

Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre

Our Mission and Goals

The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).

ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:

• Subsidizing new, emerging, and underserved student theatre programs;
• Creating paths for theatre educators to develop new skills; and
• Commissioning research to showcase the value of a theatre education.

Grants for Educators & Theatre Programs

A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.

For EdTA Members

Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.

Production Grants

Show-specific financial assistance for educational theatre programs

The Wilder Estate: The Long Christmas Dinner Festival Grant

In 1931, Thornton Wilder wrote The Long Christmas Dinner, a moving, funny, and ingeniously theatrical one-act play created specifically for student theater groups. In just 40 minutes, a single holiday meal becomes a 90-year journey through four generations of a family, exploring time, tradition, family, and the stories we tell about our lives.

In 2026, the Wilder Estate is launching The Long Christmas Dinner Festival, a national holiday celebration bringing schools, cultural organizations, and audiences together around this remarkable play.

Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre

Our Mission and Goals

The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).

ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:

• Subsidizing new, emerging, and underserved student theatre programs;
• Creating paths for theatre educators to develop new skills; and
• Commissioning research to showcase the value of a theatre education.

Grants for Educators & Theatre Programs

A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.

For EdTA Members

Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.

Production Grants

Show-specific financial assistance for educational theatre programs

Music Theatre International: Heart of Rock and Roll "The Power of Love" Grant

Heart of Rock and Roll features a book by Jonathan Abrams and music and lyrics by Huey Lewis and his pop-rock band, Huey Lewis and the News, with new orchestrations of their music by Brian Usifer.

Selected schools will host intergenerational community events or outreach programs of their own design — because just as Huey Lewis’s music has always brought people together, school theatre has the power to do the same.

The CIF Capacity Builder Awards by Endeavor Health focus on enhancing community health through strategic investments. With over $38.5 million allocated to local partnerships, these awards aim to address critical areas like healthcare access, food insecurity, and workforce development. Designed for nonprofit organizations, the awards range from $100,000 to $500,000 annually for 1-2 years, fostering long-term community impact and advancing health equity in the service areas.

About American-Scandinavian Foundation (ASF)The American-Scandinavian Foundation (ASF) promotes firsthand exchange of intellectual and creative influence between the United States and the Nordic countries: Denmark, Finland, Iceland, Norway, and Sweden. ASF offers fellowships, cultural grants, internships/training, publications, exhibitions and other public programs reinforcing the strong relationships between the two regions, honoring their shared values, and appreciating their differences.ASF Public Projects GrantThe American-Scandinavian Foundation promotes the cultures of the Nordic countries in the United States and American culture in the Nordic countries by encouraging programs that will enhance public appreciation of culture, art, and thought. In establishing priorities, the Foundation considers the lasting benefits that may be achieved by any grant and favors projects where its contribution will complement support from other sources. 

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Newman-Galas Entrepreneurial Initiative

The Harold Newman and David Galas Entrepreneurial Initiative provides financial and professional support to Hertz Fellows who propose the most innovative entrepreneurial projects, with particular emphasis on collaboration among fellows. Awardees receive investments up to $25,000 to fund their work and receive mentoring from successful entrepreneurs within the fellows community.

Fueling Entrepreneurs

The initiative was established by honorary Hertz Fellow Harold Newman, a former member of our board of directors and a long-time supporter of and generous donor to the foundation. Newman changed the name to the Harold Newman and David Galas Entrepreneurial Initiative in honor of David Galas, a Hertz Fellow and chairman of the board. Through Newman’s substantial endowment, this award has helped enterprising fellows co-found 11 companies and develop new technologies with real-world impact.

The funds are provided with no strings attached, only the expectation that project leaders will be motivated to share their success with the foundation.

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Hertz Thesis Prize

The Hertz Thesis Prize recognizes fellows who publish exemplary doctoral theses with applications to real-world problems. Winners receive a $5,000 honorarium.

Exemplary Graduate Work

Since 1981, more than 60 fellows have been recognized with the Hertz Thesis Prize. Much of their work has led to successful patents, the formation of influential companies and contributed solutions to some of our most pressing challenges.

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Hertz Foundation Travel Fund

The Hertz Foundation Travel Fund provides financial support to Hertz Fellows to advance their professional growth through conference travel and interdisciplinary engagement. Awardees receive a lump sum of $2,000 for domestic or $5,000 for international travel.

Supporting professional development

Established in 2025, this funding provides Fellows with critical support to enhance their career and professional development. Funding is designated to support travel to attend technical conferences, interdisciplinary or entrepreneurial convenings and workshops or seminars that catalyze new career paths, research directions or cross-sector collaborations.

About NIF

Advancing Equality for All Israelis

The New Israel Fund (NIF) helps Israel live up to its founders’ vision of a society that ensures complete equality to all its inhabitants. Our aim is to advance liberal democracy, including freedom of speech and minority rights, and to fight the inequality, injustice and extremism that diminish Israel.

From Israel’s first rape crisis centers, to fighting discrimination, NIF-funded organizations have driven positive social change and furthered justice and equality. NIF has provided over $350 million to more than 950 organizations since our inception in 1979.

Naomi Chazan Global Activism Fellowship

Want to travel to Israel/Palestine while advancing equality, democracy, and peace for all?

The New Israel Fund’s Naomi Chazan Global Activism Fellowship offers a one-of-a-kind opportunity to visit Israel/Palestine, meet frontline Israeli and Palestinian activists, and learn about issues of war, peace, and inequality by seeing the reality on the ground. 

Fellows will visit Israel/Palestine on November 3-10, 2026.

This trip is a great opportunity to learn alongside peers and friends (ages 21 – 35). NIF is based on the simple idea that those of us who share a commitment to Israel/Palestine and to progressive values can join together to work for equality, freedom, and human rights. You will join a cohort of participants from the U.S. and Canada building relationships across borders to be sustained for years to come.

Following the trip, participants are expected to organize at least two NIF events in their home communities, with support from NIF staff. These events could look like a report-back highlighting the participants’ learnings from the trip, educational programs featuring NIF grantees/partners, or something else entirely that is tailored to the intellectual, emotional, and spiritual needs of the fellow’s communities.

The program is subsidized by generous donors in the NIF community. All “on-the-ground” costs—your hotel accommodation and almost all meals—will be covered by NIF. Participants are responsible for purchasing their own airfare and travel/health insurance. If the cost of airfare is a barrier for you, please apply anyway. Limited airfare subsidies may be available.

About Us

The Arthur L. Carter Journalism Institute at NYU

We want to educate those who agree. Opportunities abound in the media world, but at NYU Journalism, the opportunity to do compelling work that informs, engages, and matters to the societies in which we live drives our faculty, motivates our students, and shapes our approach.

Those who find this their calling will discover encouragement, support, and an endless amount to learn at NYU. Our graduates are able to work anywhere their talents take them, and they do. Students come here not only to gain competence in the journalist’s craft but also the tools to make it better than it is. And those two things are the essence of what we teach.

Matthew Power Literary Reporting Award

Matthew Power was an award-winning journalist who reported empathetically on the human condition. He died in March 2014, while on assignment in Uganda.

About the Award

The Matthew Power Literary Reporting Award is a grant of $15,000 to support the work of a promising early-career nonfiction journalist on a story that uncovers truths about the human condition.

Offered for the first time in 2015, the Award has been endowed by individuals and organizations touched by the life and work of Matthew Power, a wide-roving and award-winning journalist who sought to live and share the experience of the individuals and places on which he was reporting. Power, a longtime friend of the Arthur L. Carter Journalism Institute, died in March 2014, while on assignment in Uganda.

The award proceeds from the recognition that many important stories need to be reported from afar, and that publications do not always have the resources to send a journalist where the story is. The money need not be used exclusively for travel, but we expect that most successful applications will include such expenses. A panel of NYU journalism professors, outside writers, and editors will review the proposals. Finalists will be asked to take part in an interview online.

The judges will be interested in perpetuating Power’s legacy, as his former editor Roger Hodge put it, of “strong, character-driven narratives with detailed scenes and lyrical description.” Power was always open to the absurdity that often attends politics and international affairs; he was always searching, as he put it, for “the human truth beneath the sorry facts.” Power’s ultimate ambition, he added, was literary beauty.

That said, judges will be looking for a journalist as singular in his or her own approach as Power was in his. In addition to longform print projects, we will consider audio projects involving substantial reporting and running over 20 minutes in length. The award will not fund proposals to report on armed conflicts where journalists are already imperiled, nor projects that are mainly investigatory. The winner will normally receive visiting scholar privileges at NYU, including library access.

Literary Arts Project Grants

As part of its Literary Arts Initiative, South Arts is pleased to announce Literary Arts Project Grants supporting literary arts organizations and small presses that focus on contemporary literary arts.

These grants advance South Arts’ commitment to amplifying the literary traditions and artistic practices of the American South by directly supporting the development, production, and public engagement of high-quality literary projects.

Literary Arts Project Grants support projects in poetry, fiction, creative or literary nonfiction, young readers’ literature, and drama (scriptwriting). Projects must demonstrate artistic excellence, editorial rigor, and meaningful public or community impact.

Award Amount

South Arts will award up to $5,000 per project to eligible literary arts organizations and small presses.

Hendrix-Murphy Foundation

Enhancing literature & language at Hendrix College since 1978.

In homage to Bertie Wilson Murphy’s passion for the study and appreciation of literature and language, the Hendrix-Murphy Foundation at Hendrix College was founded in 1978 with an endowment by her son, Charles H. Murphy, Jr., former CEO of Murphy Oil Corporation. Mrs. Murphy was a 1905 graduate of Galloway Women’s College in Searcy, Ark., which merged with Hendrix College in Conway in the 1930s. Charles H. Murphy, Jr., was a member of the Hendrix Board of Trustees and served as chair. 

The Foundation's programs are overseen by a Board of Directors that is headed by the president of the College and includes Murphy family members, the provost, and representatives from the Hendrix Board of Trustees.

The Hendrix-Murphy Book Award

Hendrix is proud to offer the Hendrix-Murphy Book Award to an outstanding high school junior who demonstrates distinguished scholarship or leadership in literary studies (English, creative writing, foreign languages, or drama).

Hendrix-Murphy Book Award recipients will receive a copy of Poems to Read: A New Favorite Poems Anthology, edited by Robert Pinsky and Maggie Dietz.

Students may be nominated by their English, languages, creative writing, or drama teacher or guidance counselor by using the required form.

The 1890 Institution Teaching, Research, and Extension Capacity Building Grants Program aims to enhance the capabilities of eligible institutions by fostering collaboration with federal and non-federal entities. This initiative supports the White House's commitment to promote excellence at Historically Black Colleges and Universities (HBCUs). By strengthening institutional teaching, research, and extension capacities, the program helps ensure that HBCUs can effectively contribute to innovative solutions in education and community development.

The Cancer Prevention and Control Programs aim to enhance cancer outcomes by funding partnerships among national, state, territorial, and tribal organizations. These initiatives focus on evidence-based strategies for cancer surveillance, prevention, and control, specifically targeting breast and cervical cancer screening for underserved populations. Through collaboration, the program seeks to improve clinical services and cancer survivorship, ultimately striving towards the vision of 'All People Free of Cancer' by leveraging resources and community involvement.

The NIH Director's New Innovator Award supports creative early-stage investigators pursuing innovative research with transformative potential for science relevant to the NIH mission. Applications are encouraged across all NIH-related fields, enhancing support for emerging talent. This award is part of the NIH Common Fund's High-Risk, High-Reward Research Program, which aims to cultivate groundbreaking research and foster the next generation of scientists.

The Residential Treatment for Pregnant and Postpartum Women program aims to deliver essential services to women facing substance use disorders. By offering comprehensive residential treatment options, the program supports both recovery and the well-being of mothers and their children. Funded by the Substance Abuse and Mental Health Services Administration, this initiative addresses the unique challenges of pregnant and postpartum women, ensuring they receive the care necessary for a successful recovery journey.

The Providers Clinical Support System – Universities program aims to equip graduate-level health professional students with the necessary skills to understand, identify, intervene, and treat patients with substance use disorders. By focusing on practical training and comprehensive education, this initiative prepares future practitioners to effectively address the challenges associated with substance misuse, ensuring they are well-prepared upon obtaining their licenses.

The NIH Director's Pioneer Award (DP1) encourages innovative research by funding exceptional scientists. This award is designed for groundbreaking projects that diverge from the investigator's current work and address significant scientific challenges relevant to the NIH mission. Applications are invited across all NIH-relevant fields, promoting high-risk, high-reward research that could transform our understanding of critical scientific areas.

The NIH Director's Early Independence Award empowers exceptional early-career researchers to embark on independent research careers immediately after their doctoral degree or post-graduate clinical training. This initiative accelerates the transition to independence, promoting innovative research across various fields aligned with the NIH mission. As part of the NIH Common Fund's High-Risk, High-Reward Research Program, it encourages groundbreaking studies that could significantly advance health-related knowledge.

The NIH Director's Transformative Research Award encourages innovative research that challenges conventional ideas. This award supports bold scientists and teams aiming to create groundbreaking technologies and new clinical approaches, ultimately transforming scientific paradigms. As part of the NIH Common Fund's High-Risk, High-Reward Research Program, it seeks to fund high-impact projects that have the potential to significantly advance science and technology.

The Emergency Department Alternatives to Opioids Program aims to implement practices that offer alternatives to opioid treatments in hospitals. This initiative focuses on reducing the harmful consequences of opioid use for pain management, promoting safer treatment options, and minimizing the risk of opioid misuse and overdose. Specifically, it targets healthcare organizations to enhance their pain care strategies, ultimately contributing to better patient safety and health outcomes.

Request for Proposals: Launchpad Funds

Background

Coefficient Giving is increasing its giving, primarily to prepare for the billions of dollars in new philanthropic capital that may become available in the coming years. Our increased giving in global health and wellbeing is a temporary surge, with two objectives: to smooth funding and pull forward initiatives we expect to be cost-effective, and to help create an ecosystem of regrantors and implementers with the capacity to allocate this new money as cost-effectively as possible. Additional context on our scaling is provided in this blog post. 

With new potential capital on the way, we want to increase the supply of actionable and fundable plans to address some of the world’s hardest problems. We’re looking for specific, credible strategies to convert funding into measurable progress. Our ideal funds are:

However, we are also open to funds that are thematic and don’t have a quantified goal — for example, a fund organized around a promising type of intervention. Such funds still need to be led by a single, identifiable person who is accountable for the fund’s direction.

Through this request for EOIs, we aim to seed or scale Launchpad Funds that can grow to $100m+ over the next few years. We don’t seek scale for its own sake; it is a proxy for the ambition of the fund, and a signal that the problem is large and tractable enough to justify deploying significantly more capital over time.

What we will fund

• We expect to support established ideas that have either not yet secured anchor support or could significantly scale beyond their existing level of funding.
• This funding can cover operating expenses, but we expect most of it to be used for activities that make progress on the fund’s goals — whether through regranting or direct implementation.
• For exceptional proposals, we may consider funding levels beyond $50m. We anticipate higher funding levels will involve more thought partnership from our team.
• While we don’t expect to make grants longer than 36 months, funded proposals may later be considered for additional funding beyond the initial period.

The NASA Innovative Advanced Concepts (NIAC) Phase I program invites proposals for groundbreaking aerospace concepts, aiming to transform potential in aeronautics. This initiative supports innovative research through multiple award phases, focusing on Phase I requirements and evaluation criteria. A virtual forum will be held on October 7, 2026, to discuss the Appendix’s details and clarify submission guidelines. Additional information will be available on the NSPIRES page, ensuring participants are well-informed about the process.

The National Parks Business Plan Internship aims to enhance the operational health of national parks through a graduate-level program that trains students in business management and NPS operations. Participants will engage in substantive analysis, gain insights into park management, and promote federal careers in conservation. This initiative seeks to involve underrepresented graduate students from disciplines such as business administration and public policy, fostering a commitment to stewardship of public lands.