Best Large Grants for Nonprofit Organizations in South Carolina

Society of Toxicology

Founded in 1961, the Society of Toxicology (SOT) is a professional and scholarly organization of scientists from academic institutions, government, and industry representing the great variety of scientists who practice toxicology in the US and abroad. The Society’s mission is to create a safer and healthier world by advancing the science and increasing the impact of toxicology. SOT operates under four guiding principles:

• Serving the needs of the scientific discipline and our members to enhance human, animal, and environmental health.
• Life-long learning and intellectual scientific stimulation.
• Diversity of representation in all activities of the Society.
• Integrity.

BMSS Perry J. Gehring Biological Modeling Endowment Award

The Biological Modeling Specialty Section (BMSS) will present the Perry J. Gehring Biological Modeling Award at the BMSS Business Meeting and Reception during the SOT Annual Meeting. This award is made possible by the Perry J. Gehring Biological Modeling Award Fund of the SOT Endowment, and it will consist of a plaque and a cash award.

Research areas of interest include all aspects of biologically based modeling and simulation, including but not limited to: modeling of complex biological systems, biological insights gained through model development and application, model validation, and mathematical/statistical/computational approaches to biological modeling.

Applicants for this award will be considered for all BMSS awards for which graduate students and postdoctoral scholars are eligible.

The DoW Ovarian Cancer Pilot Award fosters innovative research that challenges existing paradigms in ovarian cancer. It aims to propel groundbreaking discoveries and advancements in the field. Notably, the award prioritizes originality over scientific merit alone, ensuring that innovative ideas are at the forefront. The application process includes a blinded pre-application screening to maintain confidentiality and integrity, encouraging fresh perspectives in ovarian cancer research.

The Columbus Hilltop Lions Community Service Scholarship Fund, established by The Columbus Foundation in 1943, aims to support high school seniors from the Hilltop area of Columbus who demonstrate a strong commitment to community service. The scholarship offers $2,000 over two years to eligible candidates who have completed at least 30 hours of volunteer service. This initiative reflects the foundation's long-standing dedication to enhancing the quality of life in central Ohio.

The Ian Van Heyde Memorial Culinary Scholarship Fund, established by Stephen and Nancy Van Heyde, honors their son Ian, a culinary arts student from Whetstone High School. This fund provides scholarships to students pursuing postsecondary education in culinary arts, food management, or restaurant management. Award amounts start at $1,500, aimed at supporting talented individuals from central Ohio's public culinary programs. Previous recipients are encouraged to apply again, fostering continued growth in the culinary field.

The FY26 Breast Cancer Research Program's Transformative Breast Cancer Consortium Award fosters significant collaborations that aim to revolutionize care for individuals affected by breast cancer. This award supports a multidisciplinary consortium of leading scientists, clinicians, and advocates to tackle major challenges in breast cancer research. Proposals must address at least one of the program's overarching challenges and demonstrate a transformative impact that cannot be achieved by individual investigators alone.

Geological Society of America 

The Geological Society of America (GSA), founded in 1888, is a global scientific society with members from academia, government, and industry in more than 100 countries. Through its meetings, publications, and programs, GSA enhances the professional growth of geoscientists at all career levels, encourages cooperative research among earth, life, planetary, and social scientists, fosters public dialogue on geoscience issues, and promotes the geosciences in the service of humankind. GSA is headquartered in Boulder, Colorado, USA.

Jack Kleinman Memorial Award for Volcano Research

The Jack Kleinman Memorial Award for Volcano Research represents a partnership between GSA and the U.S. Geological Survey (USGS) to recognize early-career scientists conducting high-impact research in volcanology. The award was created in memory of Jack Kleinman—a USGS Cascades Volcano Observatory scientist known for his commitment to collecting high-quality field data and who relished a challenge, inspired enthusiasm in others, and delighted in the natural world. The award honors students who demonstrate these same qualities in their scientific explorations.

Up to US$5,000 may be awarded to undergraduate, graduate, and aspiring graduate students, regardless of current enrollment status. Successful proposals typically focus on geologic, geochemical, geophysical, or hazards investigations with an emphasis on fieldwork. Cooperation with a staff member from the USGS Volcano Science Center is encouraged and given considerable weight in the selection process.

Funding is intended to defray the costs of field-focused studies, such as travel to field sites, living expenses during fieldwork, field supplies, and analytical costs. Awardees are invited to present their results in the USGS Kleinman Seminar Series and attend the Awards Ceremony at the GSA annual meeting.

The Stanley Fahn Junior Faculty Award, offered by the Parkinson's Foundation, supports early-career scientists in Parkinson's research. With $300,000 in funding over three years, it aims to bridge the gap for junior faculty transitioning to independent research. Eligible applicants must hold a PhD or MD and be U.S. or Canadian faculty members. This award promotes innovative research proposals that advance understanding and treatment of Parkinson's disease, fostering the next generation of scientists in this critical field.

The Installed Building Products Building for Tomorrow Scholarship, established by The Columbus Foundation, aims to support employees and their families in pursuing educational goals. Award amounts include $5,000 annually for the duration of a program or degree, with a special $10,000 scholarship for a candidate demonstrating the highest financial need. Open to anyone attending accredited institutions in the U.S., preference is given to those in construction-related fields.

Our Mission

The Mission of Kids Chance of Nebraska is to provide financial support to further the education of the children of Nebraska workers who have been severely injured, totally disabled or killed as a result of employment related injuries or occupational diseases. It is the goal of Kids’ Chance of Nebraska to make a difference in the lives of these children by providing scholarships to help eligible students achieve both their educational goals and their families’ dreams.

Scholarship Application Process

Kids’ Chance of Nebraska (KCNE) provides college scholarships to the children of Nebraska workers who have been severely or fatally injured in a workplace-related accident. KCNE awards as many scholarships as the current year’s funding will allow.

We open our application portal twice a year, Fall and Winter.

About All Points North Foundation

All Points North Foundation is dedicated to navigating communities upward.

All Points North Foundation was founded in 2011 by a family who believes passionately that everyone has a “true North” – a place of achievement – and that everyone should have equal opportunity and access to realize their goals.

Our Vision

We envision a nation where the middle school years are seen as an important, vital time in the lives of youth, and where the public middle school education experience in underserved communities measurably improves

We also envision a nation where the integration of solar benefits families, local economies and the environment.

Our Priorities

All Points North Foundation funds grantees in two areas – public middle school education (grades 6-8) and solar – that have the power to help communities nationwide navigate upward.

Grant Making

All Points North Foundation seeks collaborative partnerships with grantees in our two priority areas.

Education

All Points North Foundation is one of the few foundations focused on public middle school education, defined as grades six through eight. We recognize the vital importance of the middle school years in shaping the future of our nation’s youth.

All Points North Foundation seeks to measurably improve public middle school education in underserved communities, whether urban or rural, through two priorities:

• Funding programs that prepare and retain middle school teachers in an ever-changing education climate.
• Helping students grow both academically and socially/emotionally.

Middle schoolers need a nurturing school environment and expertly trained, passionate teachers who can help foster academic, social and emotional growth.

It’s critical for teachers to be adequately prepared for rapidly changing classrooms and school environments, and to be continuously encouraged and inspired to serve as key role models for middle school students.

It’s also critical for middle school students to be inspired and engaged, and excited to embrace the path of learning ahead. Research clearly indicates the habits and patterns set in middle school forecast success for students in their high school years and beyond.

The Community Foundation of Carroll County supports nearly 70 academic, sports, special circumstances, and 4-H scholarships. Search scholarships by name, or sort by application type.

Christopher H Knorr Memorial Scholarship

In July of 2022, Chris Knorr unexpectedly passed away. Chris Knorr was a loving father, baseball/softball/basketball coach in the area, an active member of his church, and a friendly face to all in the community. Chris always believed everyone should follow their heart and make an impact in any way possible. Our goal is to raise money for scholarships for South Carroll, Century and Liberty High School that goes to 1 or 2 seniors at each school who is involved in the community and made an impact, and to continue on his legacy.

• Scholarships are one time only.
• The amount of the award will vary based upon the earnings of the fund, minimum $500 per scholarship.
• The money shall be transmitted by the Foundation directly to the desired college or university and applied directly to the student's tuition and books. The monies shall not be remitted to the scholarship winner.

Youth Service America

Youth Service America believes that youth, communities, and our democracy thrive when we all work together for the common good. YSA is a leading global nonprofit that activates young people, ages 5-25, to find their voice, take action, and acquire powerful civic and 21st Century skills as they solve problems facing their communities. YSA supports its activation campaigns with grants, training and resources, and recognition programs for young people and their adult champions. Youth-led projects use Awareness, Service, Advocacy, and Philanthropy (ASAP) strategies to create social and environmental change.

We Serve To Remember Grants

Projects that Engage 100 Youth Volunteers

YSA’s We Serve to Remember 9/11 Day of Service Grants are for organizations, schools, and youth changemakers ages 5-25 to lead service projects on or around September 11, 2026. Programming efforts should also honor and pay tribute to those who lost their lives on September 11, 2001, their families, and those who rose in service in response to that tragedy. (We suggest starting with eleven reflections about 9/11/01 and related ideas for service or service-learning projects.)

Grantees are required to engage at least 100 youth as volunteers in planning and implementing the service activities.

What are we looking for?

• Projects must be youth-led;
• Projects must include elements to honor and pay tribute to those who lost their lives on 9/11, their families, and those who rose in service in response;
• Projects must take place on or around September 11th National Day of Service and Remembrance (Friday, September 11, 2026) – between Friday, September 4 and Friday, September 18;
• Project organizers must make their best effort to recruit and engage youth volunteers who are not usually asked to serve;

Grantees are also required to provide evidence of volunteer participation and number of hours served. Approved documention includes sign in sheets, copies of pre-and-post-surveys, or reports from school attendance or volunteer management system. These documents must contain a unique identifier for each volunteer, such as the volunteer’s full first and last name, their full first name and last initial, or a volunteer/student ID number.

Reflecting on the spirit of togetherness that brought people together in the days, weeks, and months after September 11th, we are especially looking for ideas that bring together all members of the community.

About PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

Our Mission

PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.

Addressing Sensory Health Needs Across the Lifespan PCORI Funding

The Patient-Centered Outcomes Research Institute (PCORI) intends to issue the Addressing Sensory Health Needs Across the Lifespan PCORI Funding Announcement (PFA) seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects that focus on advancing care and outcomes across the lifespan for people living with sensory health conditions. Proposed CER projects should inform health decisions for people with sensory disorders, their families and care partners in the United States experiencing high burdens and practice variations in sensory health care and outcomes. 

Research Initiative Highlights

This topical PFA will solicit applications proposing to address patient-centered CER questions that will fill evidence gaps in the areas of screening, treatment, support services and interventions that address health outcomes associated with sensory conditions.

PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAEs). The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach.

• Increasing screening and early detection for people with sensory health conditions
• Improving treatment and care coordination for people with sensory health conditions
• Enhancing support services to improve mental health and address stigma experienced by individuals with sensory health conditions, their families and their care partners

In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes. 

The AABCF Research Grants, offered by the American Association of Birth Centers Foundation, provide funding up to $5,000 for research projects focused on the birth center model of care. Open to individuals and organizations, these grants aim to enhance knowledge and practices in maternity and women's health care. Projects must demonstrate a clear plan and ability to complete the research on schedule, ensuring impactful contributions to the field.

The Pediatric Cancer Research Foundation (PCRF) is dedicated to funding innovative research aimed at curing childhood cancer. With a focus on collaborative efforts, PCRF has contributed over $51 million since 1982, significantly improving survival rates for childhood cancers. The Translational Research Grant supports cutting-edge clinical trials and therapeutic approaches, enhancing the journey from laboratory discoveries to patient care. This initiative underscores the urgent need for effective treatments, offering hope for children diagnosed with cancer and their families.

The FY26 Vision Research Program's Investigator-Initiated Research Award (IIRA) offers funding for innovative research addressing eye injury and visual dysfunction due to military exposure. This award supports preclinical to early translational studies aligned with specific focus areas. Unique features include two funding levels and a Partnering Principal Investigator Option. Applications undergo rigorous peer review based on research rationale, strategy, and impact, with potential for sharing with the National Eye Institute for additional funding consideration.

The FY26 Vision Research Program Clinical Trial Award supports the swift execution of clinical trials aimed at improving treatments for service-connected eye injuries and visual dysfunction. This award emphasizes the need for regulatory compliance, including IND/IDE submissions, and requires documentation confirming the application's active status by March 1, 2027. Review criteria focus on clinical impact, research feasibility, recruitment strategies, and ethical considerations, ensuring relevance to military health.

The DoW Vision Research Program's FY26 Translational Research Award aims to accelerate the development of innovative drugs, devices, or clinical guidelines ready for clinical trials. It supports preclinical studies and pilot trials, ensuring alignment with specified VRP Focus Areas. Key features include a requirement for regulatory expertise in drug/device development and a unique Partnering Principal Investigator option. Review criteria focus on research rationale, strategy, feasibility, and impact, enhancing military health outcomes.

About NCCF

For more than 50 years, NCCF has been taking on tough problems to improve the quality-of-life in Northwest CT by supporting nonprofits that speak to the charitable passions of our generous donors.

NCCF is a Community Foundation, a tax-exempt public charity that enables donors to establish funds that support the work of local nonprofits through grants and provide scholarships to local students.

NCCF's Board and Staff champion the causes you care about with smart grant-making designed specifically to adapt over time and provide highly attentive, knowledgeable, and compassionate service that brings donors and organizations together to address community issues.

Scholarship Opportunities and Applications

Through the generosity of fundholders and donors, NCCF has awarded more than half a million dollars in scholarships to assist students in Northwest Connecticut with the cost of higher education.

Michele Farley Pittler Scholarship

• Academic Focus: Unspecified
• Award Average: $1,000

Nebraska Community Foundation

Nebraska Community Foundation was established in 1994 by a group of visionaries determined to empower communities throughout the state to grow and prosper. They believed that with the right tools and resources, people could build the hometowns of their dreams.

Through philanthropy, our team helps communities develop strong local economies, high quality of life, and abundant leadership and volunteer opportunities. We empower local leaders to identify community assets, invest in their own resources, and bring about their own positive change. 

BCAFF Scholarships

The Butler County Area Foundation Fund is offering three scholarships to graduating seniors who meet individual scholarship criteria. These scholarships are the Butler County Clinic Scholarship (medical field major); Charles O. & Grace M. Stoops Scholarship in Agricultural or Environmental Studies; and Butler County Area Foundation Fund Scholarship.

Charles O. & Grace M. Stoops Scholarship in Agricultural or Environmental Studies

• Funding for this scholarship through the Butler County Area Foundation Fund has been provided by a gift of Grace M. Stoops and the late Charles O. Stoops of Montecito, California. Scholarship funds are available for students whose major field of study is agricultural or environmental studies.

• Two $1000 scholarships will be awarded annually to resident graduates of David City High School, Aquinas High School, or East Butler High School. Additionally, a student who is a resident of Butler County who attends a school outside of Butler County, is also eligible. Each applicant may be an entering freshman or an upperclassman enrolled for post-secondary education at an accredited school of higher education in the general areas of agriculture or environmental studies.

• Each scholarship must be used at a post-secondary accredited school of higher education.

• Scholarship funds will be paid directly to the school after the student has successfully completed the first semester.

UNCF Health Careers Scholarship

The UNCF Health Careers Scholarship Program is designed to assist in the development of a more diverse workforce in health professions in Greater Cleveland. University Hospitals, Cleveland Clinic and Kaiser Foundation are partnering with UNCF to develop an endowed scholarship for students of CSSM (Cleveland School of Science and Medicine) at John Hay High School who plan to enter the health professions.

Eligible students will receive a $5,000 merit-based scholarship in the Academic Year 2026-2027. Award recipients may be eligible for renewals for the subsequent years provided they continue to meet the criteria.

The Mae Casali Bonvicini Scholarship, offered by the Northwest Connecticut Community Foundation, supports Torrington High School graduating seniors aiming for higher education. With awards ranging from $400 to $1,500, this scholarship is designed to ease financial burdens for students who are U.S. citizens or permanent residents in the NCCF’s service area. For over 50 years, NCCF has dedicated itself to enhancing the quality of life in Northwest Connecticut through grants and scholarships.

Each year, Innovia awards over $400,000 in scholarships to deserving students like you who are college-bound or pursuing vocational or technical training. Single scholarship awards range between $500 and $4,000.

Spokane Area Swimming Adam England Memorial Scholarship

Graduating high school seniors in all counties served by the Foundation are eligible to apply. Applicants must have participated in competitive swimming meets while in high school and must submit a letter of recommendation from a coach confirming participation in these swimming meets. Applicants must have a minimum 3.5 GPA and plan to enroll in post-high school program at full-time status.

CAAM Fellowship

Maker and project development opportunity with a focus on nurturing mentor-fellow relationships within the Asian American documentary community.

The CAAM Fellowship Program aims to support documentary filmmakers developing Asian American stories by pairing selected Fellows with accomplished professionals as Mentors for six months to nurture both a project and the Fellow’s career in documentary filmmaking. 

These Mentors will be working one on one with their Fellows on their documentary projects and engage in virtual and in-person opportunities to nurture the full cohort. 

This year’s CAAM Fellowship is an opportunity to support filmmakers in the Midwest, a region that has been home to Asian Americans since before the U.S. was founded, especially for key sub-communities, such as the Hmong American community in Minneapolis, Michigan’s Muslim American communities, along with many others. This Fellowship continues CAAM’s commitment to uplifting nuanced, community-centered storytelling across the country.

The Fellowship includes one-on-one mentor meetings, monthly cohort gatherings, and participation in programs like the CAAMFest Filmmaker Summit and Ready, Set, Pitch! — building a lasting community of documentary makers.

The Women's Initiative for Screening and Health (WISH) aims to enhance women's health by improving access to preventive services. It focuses on updating HRSA-supported guidelines, increasing awareness of these guidelines, and promoting their adoption in clinical practice. By collaborating with healthcare providers, academic institutions, and patient organizations, WISH strives to implement a comprehensive strategy that benefits women's health across their lifespan.

United Institute for Theatre Technology

The United States Institute for Theatre Technology (USITT) connects performing arts design and technology communities to ensure a vibrant dialog among practitioners, educators, and students.

Driven by our core values of inclusion, excellence, and responsibility, we provide mentorship programs, exhibit opportunities, grant funding, awards, and other opportunities for our members and for the entertainment industry. 

Emerging Digital Design Showcase

USITT is seeking expressions of interest from students and early-career creatives to participate in the Emerging Digital Design Showcase during the USITT26 Annual Conference & Stage Expo. Presented on the main USITT Awards Stage, this curated showcase highlights the next generation of digital and graphic designers working in performance, live events, and immersive environments.

This year’s showcase is inspired by the ocean, coastal environments, and the world beneath the surface — reflecting both the Long Beach location and the ideas of depth, motion, and interconnectedness inherent in live performance. Designers are encouraged to interpret the theme broadly rather than literally.

This showcase is not a competition; rather, it is intended as a platform for visibility, mentorship, and the celebration of emerging voices within the USITT community.

The Edward W. Diskavich Scholarship, established by the Northwest Connecticut Community Foundation, honors the legacy of Edward W. Diskavich. It aims to support students from Oliver Wolcott Technical High School who are U.S. citizens or permanent residents in the service area. With awards ranging from $300 to $1,000, this scholarship helps alleviate the financial burden of higher education for deserving students, reflecting NCCF's commitment to enhancing community well-being through accessible educational opportunities.