Best Grants for 501(c)(3) in South Carolina

South Carolina agricultural producers, non-industrial private forest landowners, Tribes, and water management entities can access funding through the Natural Resources Conservation Service to implement conservation practices on working lands. Support covers technical and financial assistance to improve soil health, water and air quality, wildlife habitat, and climate resilience on eligible cropland, rangeland, pasture, and forestland.

Tax-exempt 501(c)(3) and 509(a) organizations working in education, human services, conservation, health, or cultural programs, including those in South Carolina, can apply for McGraw Foundation support. Grants of US $2,000 - US $10,000 may fund general operating support, specific projects, or occasional capital needs, primarily for organizations in the greater Chicago area.

South Carolina agricultural and forest producers seeking to enhance conservation on working lands can receive financial and technical assistance to improve soil, water, wildlife habitat, and overall environmental stewardship. USDA Natural Resources Conservation Service of South Carolina provides annual CSP payments of more than US $4,000 for maintaining and adding conservation practices through five-year whole-operation contracts.

501(c)(3) nonprofits providing community-focused services in areas like education, basic needs, health, environment, or economic opportunity can be nominated for BECU Foundation’s People Helping People Awards, with grants up to Up to US $50,000. Eligible organizations must have direct impact in Charleston County, South Carolina and be nominated by a BECU member.

Graduate students pursuing research in drinking water quality, environmental science, or public health can receive US $3,000 to address current water industry challenges. Focused on applied research outcomes, the Dr. Philip C. Singer Scholarship from American Water Works Association may benefit students connected to 501(c)(3) organizations in South Carolina.

Nonprofit 501(c)(3) public charities working in the Carolinas on education, healthcare, human services, or Jewish values may be eligible for funding to strengthen programs and organizational capacity. With a mission to foster self-sufficiency and lasting change, Leon Levine Foundation provides South Carolina organizations with support for proven, financially sustainable initiatives.

With a mission to protect the planet, American Honda Motor provides South Carolina 501(c)(3) nonprofits and schools with US $25,000 - US $100,000 for environmental programs. Funding supports decarbonization, clean energy, and efficient use of natural resources in communities where Honda associates live and work, including recycling, solar or wind projects, and greenspace initiatives.

South Carolina 501(c)(3) nonprofits and eligible public entities serving a Weyerhaeuser community can seek funding for local programs in areas like affordable housing, youth development, and environmental stewardship. Weyerhaeuser Giving Fund awards more than US $1,000 for projects that address community needs and demonstrate strong local support and impact.

South Carolina 501(c)(3) organizations serving women and children through humanitarian aid, education, health care, or self-sufficiency programs can apply for funding from The Father's Table Foundation. This highly selective grant supports projects that build long-term resilience, including homelessness services, employment assistance, microfinance, food security, and related support, with awards up to US $750,000.

South Carolina 501(c)(3) nonprofits running programs in education, environment, culture, arts, community development, or health and human services can seek US $1,000 - US $15,000 to support specific projects. With a mission to strengthen communities, Dominion Energy Charitable Foundation provides two online grant cycles each year for organizations in its South Carolina service area.

Undergraduate-focused higher education institutions in South Carolina conducting biomedical and health-related research can receive up to US $375,000 to support small-scale projects and student research experiences. The National Institutes of Health funds AREA (R15) awards for colleges that grant baccalaureate science degrees and have historically received limited NIH support, including eligible 501(c)(3) institutions.

South Carolina 501(c)(3) charities managing humanitarian, education, environmental, or arts projects may be eligible for philanthropic support that advances sustainable development and community benefit. Roche supports initiatives worldwide that are locally managed, high quality, and innovative, especially those engaging Roche expertise and employees in social, scientific, community, or contemporary arts activities.

Early-career research scientists at academic or research institutions in eligible low- and middle-income countries can apply for the Emerging Global Leader Award to secure protected time and support for independent clinical trial research. Grants from the National Institutes of Health help South Carolina-based 501(c)(3)s partnering with LMIC investigators participate in global health and disease-focused research collaborations.

Early-career research scientists at academic or research institutions in eligible low- and middle-income countries can apply for the Emerging Global Leader Award from the National Institutes of Health, with approximately US $140,000 to support mentored health research career development. South Carolina-based 501(c)(3) partners collaborating with LMIC investigators may benefit through joint projects and mentorship roles.

Nonprofit 501(c)(3) organizations can seek funding for education-focused programs, with additional support possible for arts, youth, community initiatives, and select environmental or preservation projects. Focused on educational impact, John Ben Snow Memorial Trust invites U.S. nonprofits, including those serving South Carolina, to apply for grants typically ranging from US $5,000 - US $20,000.

South Carolina 501(c)(3) organizations and similar entities hosting medical or scientific congresses, events, or initiatives can seek sponsorship that offers Biogen tangible benefits like exhibits or marketing visibility. Biogen Foundation considers a wide range of disease areas, including neurology, dementia, Alzheimer’s, multiple sclerosis, Parkinson’s, lupus, ALS, stroke, and related conditions.

South Carolina 501(c)(3) organizations working in economic and community development, education and workforce readiness, financial wellness, arts and culture, veterans, or disability services can benefit from Regions Bank’s Matching Gifts for Recent Retirees, offering up to US $1,000 per retiree per year. Eligible nonprofits receive matched donations from recent Regions retirees within the bank’s footprint.

501(c)(3) organizations in South Carolina working in economic development, education, financial wellness, arts and culture, veterans, or disability services can benefit from Regions Bank’s Matching Gifts Program for full-time associates. Eligible nonprofits within the Regions footprint receive matched donations when supported by Regions associates or recent retirees, helping deepen individual charitable contributions.

South Carolina 501(c)(3) nonprofits, government agencies, and tax-exempt educational or research institutions can seek funding to improve health outcomes and expand access to care, especially for economically vulnerable residents. South Carolina health organizations can access funding through Blue Cross Blue Shield of South Carolina Foundation for initiatives in oral health, mental health, primary care, community health education, and related services.

501(c)(3) nonprofits, including those in South Carolina, can seek US $5,000 - US $50,000 from Clif Family Foundation for general operating support of environmental, climate justice, sustainable agriculture, and healthy food access work. Focused on grassroots, community-based change, the foundation prioritizes smaller U.S. organizations advancing regenerative farming, pollution prevention, and inclusive outdoor access.

The Data Center Community Grants Program (US-CBF) supports nonprofit organizations that enhance their local communities surrounding Google data centers. Funding is available for projects focused on education, economic opportunity, bridging the digital divide, sustainability, health, and arts. Grants typically range from $5,000 to $50,000, prioritizing measurable community benefits and innovative approaches. Eligible projects must demonstrate long-term impact, while operational expenses are generally ineligible. This initiative aims to empower underserved groups and foster collaboration within local ecosystems.

The William and Helen Thomas Charitable Trust provides funding to nonprofit organizations focused on education, environmental protection, medical research, and support for the underprivileged. This trust, based in Florida, primarily serves communities in Palm Beach, Martin, and St. Lucie Counties, along with select areas in Appalachia. It seeks to assist public charities classified under Section 501(c)(3) of the Internal Revenue Code, ensuring support for impactful charitable initiatives.

The AmeriHealth Caritas Foundation Grant aims to prevent and mitigate adverse childhood experiences (ACEs) to promote healthier outcomes for children. With a focus on empowering families, healing behaviors, and access to healthcare, the foundation supports nonprofit organizations that provide comprehensive care and resources. Grants range from $100,000 to $250,000, totaling up to $1.945 million for project-specific initiatives. Eligible organizations must be 501(c)(3) nonprofits operating in states where AmeriHealth Caritas Medicaid markets exist.

The Soil and Water Stewardship Scholarship, sponsored by the Community Foundation of Northern Illinois, provides financial support to students pursuing careers in natural resources. Applicants must reside in specific Illinois counties and plan to enroll in a full-time program related to fields such as ecology, hydrology, and conservation. Academic performance is a key consideration in the selection process. For more details, contact the Winnebago County Soil & Water Conservation District.

The Frances P. Bunnelle Foundation offers the Grants for the Common Good in Fall to support organizations in Georgetown County, SC. Grants of up to $15,000 can fund general operations or special projects addressing poverty, basic human needs, economic vitality, and environmental preservation. Eligible entities include IRS-certified 501(c)(3) charities and government bodies, with a limit of one grant per year. Applications must demonstrate impactful use of funds within a nine-month term.

The Spartanburg County Foundation offers Nonprofit Effectiveness Grants of up to $10,000 to enhance the internal capacity of community-based organizations in Spartanburg County. These grants aim to strengthen governance, financial management, and overall organizational effectiveness. Eligible organizations must be recognized 501(c)(3) nonprofits serving Spartanburg residents, demonstrating alignment with the Foundation's mission and measurable impact. The Foundation seeks to promote philanthropy and community engagement, ensuring that funds are utilized to benefit local residents directly.

The Spartanburg County Foundation's Continuous Improvement Grant aims to enhance the lives of Spartanburg County residents by funding nonprofit organizations that focus on quality of life, educational achievement, and economic mobility. Grants of up to $35,000 are available to eligible 501(c)(3) organizations. The foundation prioritizes projects that demonstrate alignment with its mission, utilize data-driven strategies, and foster community engagement, ensuring diverse populations receive necessary support and resources.