Best Large Grants for Nonprofit Organizations in South Carolina

The Edna Mae Scholarship, offered by the Community Foundation of Southern New Mexico, aims to support women from rural communities in their pursuit of higher education at vocational community colleges or universities. This scholarship is open to applicants actively enrolled in any form of higher education, including undergraduate and vocational programs, with a special focus on assisting those in need. Applicants must be graduating high school seniors or currently enrolled students.

The Drops of Hope Giving Program, initiated by Vapur, aims to enhance environmental sustainability by reducing single-use plastics. This initiative collaborates with organizations to donate thousands of reusable bottles globally, promoting access to clean water. Eligible applicants include registered 501(c)3 nonprofit organizations or those offering marketing opportunities in exchange for contributions. The program reflects Vapur's commitment to innovative, portable products that inspire active lifestyles, fostering a healthier planet.

The Presbyterian Committee on the Self-Development of People Grant Program supports projects led by economically disadvantaged communities to combat poverty and injustice. By promoting justice, building stronger communities, and advocating for economic equity, this program empowers individuals and groups to address the root causes of their struggles. The initiative seeks sustainable solutions that respect the environment and reject violence, fostering long-term positive change in society.

The Rocky Talkie Search and Rescue Award, sponsored by the American Alpine Club, provides $75,000 annually to support underfunded Search and Rescue (SAR) teams in the U.S. and Canada. The initiative aims to enhance community awareness of the vital contributions made by volunteer SAR members. Grants include $10,000 for five selected teams and a special $25,000 award for the Featured Rescue of the Year, spotlighting exceptional volunteer-led rescue operations and their impact on mountain safety.

The E. Rhodes and Leona B. Carpenter Foundation, established in 1975, supports public charities with a focus on Asian art, performing arts in Richmond, VA, and graduate theological education. The Foundation prioritizes requests from organizations with historical ties to the Carpenters and those promoting LGBTQ+ inclusion and community health. It aims to enhance cultural exchange through art exhibitions, particularly in the US and China, while excluding support for private education and large public charities.

The John William Pope Foundation offers annual grants to support public policy research promoting a free-market economy and individual liberty under the rule of law. Emphasizing the importance of property rights and personal initiative, the foundation welcomes proposals from tax-exempt organizations, particularly those impacting public policy in North Carolina. By focusing on long-term solutions rather than short-term aid, the foundation aims to empower communities and foster sustainable economic growth.

The National Institute on Aging is announcing a Notice of Funding Opportunity for the Claude D. Pepper Older Americans Independence Centers (OAICs) award. This initiative aims to establish centers of excellence in geriatrics research and education to enhance the independence of older adults. Applicants are encouraged to identify a research focus that fosters collaboration and education in aging. Though applications are not currently being accepted, this notice allows potential applicants to prepare meaningful projects. The P30 activity code will be utilized.

The Pershing Square Sohn Cancer Prize is awarded to early-career scientists in the New York area who are pursuing innovative cancer research. Established by the Pershing Square Foundation in partnership with The Sohn Conference Foundation, the prize offers $250,000 annually for up to three years. With a commitment of over $49 million since 2013, the Alliance aims to accelerate cancer cures by fostering collaborations between academia and industry, providing a unique network and access to vital resources for groundbreaking research.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Robert J. and Norma E. Bazzett Scholarship

This scholarship has been made possible by the generosity of Robert J. and Norma E. Bazzett, who established the Robert J. and Norma E. Bazzett Scholarship of the Community Foundation for Mason County.

Robert, a 1959 graduate of Ludington High School, said he always had the idea in the back of his mind to establish a scholarship fund for the “average” student. “I always felt there was a need for that,” Robert said, “because there are a lot of kids like me that were just average C students in high school. We were cut out of the scholarship picture because our grades weren’t good enough, but that didn’t mean we were not worthy of a scholarship.”

The Americana Foundation's American Heritage Grant aims to support projects that broaden inclusivity in early American art and narratives, especially for underrepresented groups. Recognizing the historical significance of Americana, the foundation prioritizes initiatives that promote understanding and appreciation of America's diverse heritage. Eligible applicants include nonprofit organizations and municipal entities. The foundation encourages innovative projects that reinterpret early American material culture, fostering a deeper connection to the past for future generations.

The Community Foundation Martin – St. Lucie’s (TCFMSL) Fundholders, Friends and Partners are proud to present scholarship opportunities for graduating seniors and adults looking to upskill. Each scholarship has distinct criteria.

Jenn DuBey Career & Technical Education Scholarship

All residents of Martin or St. Lucie County.

Awards

• $Cost of program taken into account Full and partial scholarships available.

The Pre-College Education Grant from the United States-Japan Foundation aims to foster mutual understanding between young Americans and Japanese through innovative educational projects. The Foundation supports K-12 initiatives that enhance teacher training, develop curriculum materials, and promote Japanese language instruction. With a focus on engaging underserved regions and utilizing technology, this grant encourages collaborative efforts to build networks among educators and students, ensuring a rich exchange of cultural knowledge and experiences.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Adam Murphy Scholarship

This scholarship has been made possible by the generosity of Memorial Medical Center West Michigan Medical Staff for Tim and Anne Murphy, who created the Adam Murphy Scholarship of the Community Foundation for Mason County.

Adam was a gifted and talented young man. He had a sharp wit and a sense of humor. Adam was a beloved student at Ludington Area Catholic School, where he attended through the eighth grade, and was a freshman at Ludington High School at the time of his passing. He was a board designer and a member of the Varsity Quiz Bowl Team at Ludington High School. Adam actively participated in Spelling Bees and Math Counts and was a state finalist in the You Be the Chemist competition. Family and Faith were also of the utmost importance in his life.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Alberta Muzzin Chamber Alliance of Mason County Scholarship

This scholarship has been made possible by the generosity of the Ludington & Scottville Chamber of Commerce, which established the Alberta Muzzin Chamber of Commerce Scholarship Fund of the Community Foundation for Mason County.

The Make a SPLASH! Grant Contest invites municipal entities and non-profits in the U.S. to apply for the Inclusive Design Award. This award recognizes splash pads that prioritize inclusivity and accessibility. Winners will receive a customized Life Floor safety surface, valued at $50-65k, promoting community engagement and safety. With two opportunities to win, this initiative aims to enhance splash pad designs, ensuring they cater to all individuals. Join us in making splash pads safer and more accessible for everyone!

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Everett J. Liebetreu Education Scholarship

This scholarship has been made possible by the generosity of Everett J. Liebetreu, who established the Everett J. Liebetreu Scholarship of the Community Foundation for Mason County.

The McCarthey Dressman Education Foundation offers Teacher Development Grants to support K-12 educators in enhancing their classroom instruction. With grants up to $10,000 per year, individuals or small teams can implement innovative teaching strategies that foster critical inquiry and improve student engagement. This initiative aims to boost educational experiences for diverse learners, encouraging teachers to document and share their methods, ultimately promoting a culture of continuous professional growth.

The Emergency Medicine Interest Group Grant (EMIG), funded by the Society for Academic Emergency Medicine Foundation, supports medical student interest groups in enhancing emergency medicine education. Grants of up to $500 are awarded for one year, with potential for renewal. Eligible applicants include established or developing EMIGs at medical schools, focusing on educational initiatives. This grant aims to foster innovation in teaching methodologies and support resources for students pursuing education in emergency medicine.

The National Register Internship Travel Scholarship, funded by the American Psychological Foundation, offers financial assistance to psychology doctoral students for relocation to their predoctoral internship sites. This scholarship supports diverse applicants who are in good standing in accredited programs and have secured internships recognized by the APA or CPA. By alleviating relocation costs, the scholarship aims to facilitate the professional development of future psychologists.

The Paul E. Henkin School Psychology Travel Grant, offered by the American Psychological Foundation, provides up to $1,500 for student members of APA Division 16. This funding helps cover registration, lodging, and travel expenses for attending the APA Annual Convention. It encourages applicants from diverse backgrounds and requires a commitment to a career in school psychology. Eligible applicants must be current student members of APA Division 16 and cannot use the funds for food or materials not included in registration.

The Division 39 Marsha D. McCary Fund Grant for Psychoanalysis aims to enhance public understanding of psychoanalysis and its applications in various fields. This grant supports initiatives that promote psychoanalytic education, research, and services, especially benefiting early career professionals and underserved populations. The American Psychological Foundation encourages applicants from diverse backgrounds to apply, ensuring a broad representation within the field. This initiative fosters the ongoing development of psychoanalysis as a vital discipline in psychology.

The ASTRO Residents/Fellows in Radiation Oncology Seed Grant aims to advance the research careers of residents and fellows focusing on radiation oncology through funding basic, translational, and clinical research. It encourages innovative projects that enhance patient care and improve health care delivery, including cancer research and understanding radiation effects on tissues. This grant is supported by the American Society for Radiation Oncology, which seeks to foster impactful research in this vital medical field.

The OJP FY 2026 Special Attorneys Program aims to enhance the prosecutorial capacity of state, local, Tribal, and territorial agencies by assigning qualified prosecutors as Special Attorneys. These prosecutors will investigate and prosecute fraud and other crimes committed by aliens in the U.S., as well as drug and human trafficking cases. This initiative, coordinated with federal authorities, seeks to strengthen intergovernmental collaboration and ensure effective enforcement of criminal laws.

The Venturous Capital Grants aim to empower small and medium-sized not-for-profit theaters to produce bold and experimental new plays. Grants range from $5,000 to $35,000, covering extraordinary costs that enable productions to thrive. The program supports text-based, author-driven works that are ambitious, challenging, and innovative, while emphasizing the importance of playwright compensation and adhering to AEA standards. This initiative fosters creativity and helps overcome financial barriers in theater production.

About Us

We are one of over 900 community foundations in the US. We serve the 7 county Pee Dee region of South Carolina. Our mission is to improve the quality of life in our area of the state.

Who We Are

Eastern Carolina Community Foundation, founded in 2006, is the newest community foundation in South Carolina. We have a permanent endowment to meet the changing needs of the Pee Dee.

• We foster philanthropy.
• We build resources for nonprofits.
• We support our local communities.

South East Express Scholarship

In 2019, to commemorate its 25th anniversary, South East Express, Inc. in Timmonsville, SC, established a permanent endowed scholarship at Eastern Carolina Community Foundation. The award is designated for a graduating senior from Florence One High Schools in Florence County, SC where the company is located. In addition, South East Express also plans to sponsor a paid summer internship for the winning applicant to learn more about the company and how it impacts the quality of life in Florence County.

The DoW Rare Cancers Concept Award for FY26 promotes groundbreaking ideas in rare cancer research. This award encourages innovative applications that explore novel courses of investigation without requiring preliminary data. Unique to this program is the prohibition against mentioning the Principal Investigator or collaborators in the proposal materials, ensuring an unbiased review process. This funding opportunity aims to advance scientific discovery in the rare cancer domain.

The Mission Boost Grants (MBG) by the American Cancer Society aim to enhance cancer research by funding projects that translate into human testing. These grants support investigators at all levels, offering resources for innovative clinical projects. The program consists of two funding stages: Stage I focuses on developing clear milestones for new treatments, while Stage II supports patient testing, ultimately contributing to advancements in cancer care and treatment.